Research Output 1981 2018

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2018

Analogous detection of circulating tumor cells using the AccuCyte®-CyteFinder® system and ISET system in patients with locally advanced and metastatic prostate cancer

van der Toom, E. E., Groot, V. P., Glavaris, S. A., Gemenetzis, G., Chalfin, H. J., Wood, L. D., Wolfgang, C. L., de la Rosette, J. J. M. C. H., de Reijke, T. M. & Pienta, K. J. Jan 1 2018 (Accepted/In press) In : Prostate.

Research output: Research - peer-reviewArticle

Circulating Neoplastic Cells
Prostatic Neoplasms
Vimentin
Cell Count
Cell Size
Molecular Imaging
Prostatic Neoplasms
Radiotherapy
Recurrence
2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acid
Carcinoid Tumor
Prostatic Neoplasms
human glutamate carboxypeptidase II
Positron-Emission Tomography
Prostatic Neoplasms
Tomography
human glutamate carboxypeptidase II
Lymph Nodes
2017

A Bayesian hierarchical model for prediction of latent health states from multiple data sources with application to active surveillance of prostate cancer

Coley, R. Y., Fisher, A. J., Mamawala, M., Carter, H. B., Pienta, K. J. & Zeger, S. L. Jun 1 2017 In : Biometrics. 73, 2, p. 625-634 10 p.

Research output: Research - peer-reviewArticle

Bayesian Hierarchical Model
Prostate Cancer
Surveillance
Health
Prediction
Prostatic Neoplasms
Radiotherapy
Observation
Radiation
Therapeutics

A surface tension magnetophoretic device for rare cell isolation and characterization

van der Toom, E. E., Verdone, J. E., Jun, C., Petrisor, D., Lim, S., de la Rosette, J. J. M. C. H., de Reijke, T. M., Gorin, M. A., Pienta, K. J. & Stoianovici, D. Feb 1 2017 In : Medical Oncology. 34, 2, 22

Research output: Research - peer-reviewArticle

Surface Tension
Cell Separation
Equipment and Supplies
Staining and Labeling
Neoplasms

Biomanufacturing Seamless Tubular and Hollow Collagen Scaffolds with Unique Design Features and Biomechanical Properties

Singh, A., Lee, D., Sopko, N., Matsui, H., Sabnekar, P., Liu, X., Elisseeff, J., Schoenberg, M. P., Pienta, K. & Bivalacqua, T. J. 2017 (Accepted/In press) In : Advanced Healthcare Materials.

Research output: Research - peer-reviewArticle

Cell surface Thomsen-Friedenreich proteome profiling of metastatic prostate cancer cells reveals potential link with cancer stem cell-like phenotype

Li, F., Glinskii, O. V., Mooney, B. P., Rittenhouse-Olson, K., Pienta, K. J. & Glinsky, V. V. Jan 1 2017 In : Oncotarget. 8, 58, p. 98598-98608 11 p.

Research output: Research - peer-reviewArticle

Neoplastic Stem Cells
Proteome
Prostatic Neoplasms
Phenotype
Stem Cells
Circulating Neoplastic Cells
Castration
Androgen Receptors
Prostatic Neoplasms
Messenger RNA

Identifying global expression patterns and key regulators in epithelial to mesenchymal transition through multi-study integration

Parsana, P., Amend, S. R., Hernandez, J., Pienta, K. J. & Battle, A. Jun 26 2017 In : BMC Cancer. 17, 1, 447

Research output: Research - peer-reviewArticle

Epithelial-Mesenchymal Transition
Genes
Gene Expression
Prostatic Neoplasms
Cell Line

Patterns of uptake of prostate-specific membrane antigen (PSMA)-targeted 18F-DCFPyL in peripheral ganglia

Werner, R. A., Sheikhbahaei, S., Jones, K. M., Javadi, M. S., Solnes, L. B., Ross, A. E., Allaf, M. E., Pienta, K. J., Lapa, C., Buck, A. K., Higuchi, T., Pomper, M. G., Gorin, M. A. & Rowe, S. P. Aug 22 2017 (Accepted/In press) In : Annals of Nuclear Medicine. p. 1-7 7 p.

Research output: Research - peer-reviewArticle

Ganglia
human glutamate carboxypeptidase II
Prostatic Neoplasms
Sympathetic Ganglia
Aorta

Pearls and pitfalls in clinical interpretation of prostate-specific membrane antigen (PSMA)-targeted PET imaging

Sheikhbahaei, S., Afshar-Oromieh, A., Eiber, M., Solnes, L. B., Javadi, M. S., Ross, A. E., Pienta, K. J., Allaf, M. E., Haberkorn, U., Pomper, M. G., Gorin, M. A. & Rowe, S. P. Aug 1 2017 (Accepted/In press) In : European Journal of Nuclear Medicine and Molecular Imaging. p. 1-20 20 p.

Research output: Research - peer-reviewArticle

human glutamate carboxypeptidase II
Molecular Imaging
Normal Distribution
Prostatic Neoplasms
Patient Care

Prostate Cancer Local Recurrence Detected With Both 18F-Fluciclovine and PSMA-targeted 18F-DCFPyL PET/CT

Gorin, M. A., Pienta, K. J., Pomper, M. G. & Rowe, S. P. 2017 (Accepted/In press) In : Urology.

Research output: Research - peer-reviewArticle

Prostatic Neoplasms
Recurrence
1-amino-3-fluorocyclobutane-1-carboxylic acid
Positron Emission Tomography Computed Tomography
Prostate-Specific Antigen
Positron-Emission Tomography
human glutamate carboxypeptidase II
Prostatic Neoplasms
Information Systems

RB loss promotes prostate cancer metastasis

Thangavel, C. , Boopathi, E. , Liu, Y. , Haber, A. , Ertel, A. , Bhardwaj, A. , Addya, S. , Williams, N. , Ciment, S. J. , Cotzia, P. , Dean, J. L. , Snook, A. , McNair, C. , Price, M. , Hernandez, J. R. , Zhao, S. G. , Birbe, R. , McCarthy, J. B. , Turley, E. A. , Pienta, K. J. & 4 others Feng, F. Y., Dicker, A. P., Knudsen, K. E. & Den, R. B. Feb 15 2017 In : Cancer Research. 77, 4, p. 982-995 14 p.

Research output: Research - peer-reviewArticle

Prostatic Neoplasms
Neoplasm Metastasis
Neoplasms
Phenotype
Critical Pathways
Liver
Lacrimal Apparatus
Kidney
Submandibular Gland
Parotid Gland

Tenascin-C and integrin α9 mediate interactions of prostate cancer with the bone microenvironment

Martin, R. S., Pathak, R., Jain, A., Jung, S. Y., Hilsenbeck, S. G., Piña-Barba, M. C., Sikora, A. G., Pienta, K. J. & Rowley, D. R. Nov 1 2017 In : Cancer Research. 77, 21, p. 5977-5988 12 p.

Research output: Research - peer-reviewArticle

Tenascin
Bone Neoplasms
Integrins
Prostatic Neoplasms
Neoplasm Metastasis

The identification of macrophage-enriched glycoproteins using glycoproteomics

Zarif, J. C., Yang, W., Hernandez, J. R., Zhang, H. & Pienta, K. J. Jun 1 2017 In : Molecular and Cellular Proteomics. 16, 6, p. 1029-1037 9 p.

Research output: Research - peer-reviewArticle

Glycoproteins
Macrophages
Prostatic Neoplasms
Neoplasms
Membrane Glycoproteins

The prostate metastasis suppressor gene NDRG1 differentially regulates cell motility and invasion

Sharma, A., Mendonca, J., Ying, J., Kim, H. S., Verdone, J. E., Zarif, J. C., Carducci, M., Hammers, H., Pienta, K. J. & Kachhap, S. 2017 In : Molecular Oncology. 11, 6, p. 655-669 15 p.

Research output: Research - peer-reviewArticle

myc Genes
Tumor Suppressor Genes
Cell Movement
Prostate
Down-Regulation

TWIST1-WDR5-hottip regulates Hoxa9 chromatin to facilitate prostate cancer metastasis

Malek, R., Gajula, R. P., Williams, R. D., Nghiem, B., Simons, B. W., Nugent, K., Wang, H., Taparra, K., Lemtiri-Chlieh, G., Yoon, A. R., True, L., An, S. S., DeWeese, T. L., Ross, A. E., Schaeffer, E. M., Pienta, K. J., Hurley, P. J., Morrissey, C. & Tran, P. T. Jun 15 2017 In : Cancer Research. 77, 12, p. 3181-3193 13 p.

Research output: Research - peer-reviewArticle

Chromatin
Prostatic Neoplasms
Neoplasm Metastasis
Prostate
Phenotype

Uptake of the prostate-specific membrane antigen-targeted PET radiotracer 18F-DCFPyL in elastofibroma dorsi

Gorin, M. A., Mareshdeh, W., Ross, A. E., Allaf, M. E., Pienta, K. J., Pomper, M. G. & Rowe, S. P. Jul 12 2017 (Accepted/In press) In : Nuclear Medicine Communications.

Research output: Research - peer-reviewArticle

Prostatic Neoplasms
human glutamate carboxypeptidase II
2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acid
Thoracic Wall
2016

Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer

Stoyanova, T. , Riedinger, M. , Lin, S. , Faltermeier, C. M. , Smith, B. A. , Zhang, K. X. , Going, C. C. , Goldstein, A. S. , Lee, J. K. , Drake, J. M. , Rice, M. A. , Hsu, E. C. , Nowroozizadeh, B. , Castor, B. , Orellana, S. Y. , Blum, S. M. , Cheng, D. , Pienta, K. J. , Reiter, R. E. , Pitteri, S. J. & 2 others Huang, J. & Witte, O. N. Oct 18 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 42, p. E6457-E6466

Research output: Research - peer-reviewArticle

Castration
Prostatic Neoplasms
Neoplasms
Prostate
Epithelial-Mesenchymal Transition

A Novel Approach for Performing Bone Marrow Aspiration at the Time of Radical Prostatectomy

Tosoian, J. J., Reyes, D. K., Gorin, M. A., Hortopan, S., Partin, A. W., Pienta, K. J., Ross, A. E. & Schaeffer, E. M. May 1 2016 In : Urology Case Reports. 6, p. 45-46 2 p.

Research output: Research - peer-reviewArticle

Prostatectomy
Prostatic Neoplasms
Bone Marrow
Pubic Bone
Therapeutics

A phase 2 trial of salvage radiation and concurrent weekly docetaxel after a rising prostate-specific antigen level after radical prostatectomy

Jackson, W. C., Feng, F. Y., Daignault, S., Hussain, M., Smith, D., Cooney, K., Pienta, K., Jolly, S., Hollenbeck, B., Olson, K. B., Sandler, H. M., Ray, M. E. & Hamstra, D. A. Jan 1 2016 In : Advances in Radiation Oncology. 1, 1, p. 59-66 8 p.

Research output: Research - peer-reviewArticle

docetaxel
Salvage Therapy
Prostate-Specific Antigen
Prostatectomy
Radiotherapy

A phased strategy to differentiate human CD14+ monocytes into classically and alternatively activated macrophages and dendritic cells

Zarif, J. C., Hernandez, J. R., Verdone, J. E., Campbell, S. P., Drake, C. G. & Pienta, K. J. Jul 1 2016 In : BioTechniques. 61, 1, p. 33-41 9 p.

Research output: Research - peer-reviewArticle

Dendritic Cells
Monocytes
Macrophages
Cytokines
In Vitro Techniques

A simple selection-free method for detecting disseminated tumor cells (DTCs) in murine bone marrow

Valkenburg, K. C., Amend, S. R., Verdone, J. E., van der Toom, E. E., Hernandez, J. R., Gorin, M. A. & Pienta, K. J. 2016 In : Oncotarget. 7, 43, p. 69794-69803 10 p.

Research output: Research - peer-reviewArticle

Bone Marrow
Neoplasms
Neoplasm Metastasis
Biological Phenomena
Bone Neoplasms

Beyond Seed and Soil: Understanding and Targeting Metastatic Prostate Cancer; Report From the 2016 Coffey-Holden Prostate Cancer Academy Meeting

Miyahira, A. K., Roychowdhury, S., Goswami, S., Ippolito, J. E., Priceman, S. J., Pritchard, C. C., Sfanos, K. S., Subudhi, S. K., Simons, J. W., Pienta, K. J. & Soule, H. R. 2016 (Accepted/In press) In : Prostate.

Research output: Research - peer-reviewArticle

Prostatic Neoplasms
Seeds
Soil
Therapeutics
DNA Repair-Deficiency Disorders

Circulating tumour cells as biomarkers of prostate, bladder, and kidney cancer

Gorin, M. A., Verdone, J. E., van der Toom, E., Bivalacqua, T. J., Allaf, M. E. & Pienta, K. J. Nov 22 2016 (Accepted/In press) In : Nature Reviews Urology.

Research output: Research - peer-reviewArticle

Circulating Neoplastic Cells
Kidney Neoplasms
Urinary Bladder Neoplasms
Prostatic Neoplasms
Biomarkers
Prostatic Neoplasms
Immunohistochemistry
human glutamate carboxypeptidase II

Development of an Automated and Sensitive Microfluidic Device for Capturing and Characterizing Circulating Tumor Cells (CTCs) from Clinical Blood Samples

Gogoi, P., Sepehri, S., Zhou, Y., Gorin, M. A., Paolillo, C., Capoluongo, E., Gleason, K., Payne, A., Boniface, B., Cristofanilli, M., Morgan, T. M., Fortina, P., Pienta, K. J., Handique, K. & Wang, Y. 2016 In : PloS one. 11, 1, p. e0147400

Research output: Research - peer-reviewArticle

Microfluidics
Tumors
Blood
Cells
Lab-On-A-Chip Devices

Disseminated tumor cells and dormancy in prostate cancer metastasis

Van der Toom, E. E., Verdone, J. E. & Pienta, K. J. Aug 1 2016 In : Current Opinion in Biotechnology. 40, p. 9-15 7 p.

Research output: Research - peer-reviewArticle

Prostatic Neoplasms
Neoplasm Metastasis
Neoplasms
Tumors
Cells

DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis

Lee, E., Wang, J., Yumoto, K., Jung, Y., Cackowski, F. C., Decker, A. M., Li, Y., Franceschi, R. T., Pienta, K. J. & Taichman, R. S. Sep 1 2016 In : Neoplasia. 18, 9, p. 553-566 14 p.

Research output: Research - peer-reviewArticle

Epithelial-Mesenchymal Transition
Neoplastic Stem Cells
Methyltransferases
Mesenchymal Stromal Cells
Prostatic Neoplasms

Multidisciplinary intervention of early, lethal metastatic prostate cancer: Report from the 2015 Coffey-Holden Prostate Cancer Academy Meeting

Miyahira, A. K., Lang, J. M., Den, R. B., Garraway, I. P., Lotan, T. L., Ross, A. E., Stoyanova, T., Cho, S. Y., Simons, J. W., Pienta, K. J. & Soule, H. R. Feb 1 2016 In : Prostate. 76, 2, p. 125-139 15 p.

Research output: Research - peer-reviewArticle

Prostatic Neoplasms
Clinical Trials
Molecular Imaging
Tumor Biomarkers
Early Diagnosis

Murine hind limb long bone dissection and bone marrow isolation

Amend, S. R., Valkenburg, K. C. & Pienta, K. J. Apr 1 2016 In : Journal of Visualized Experiments. 2016, 110, e53936

Research output: Research - peer-reviewArticle

Dissection
Extremities
Bone Marrow
Bone and Bones
Bone

Murine prostate micro-dissection and surgical castration

Valkenburg, K. C., Amend, S. R. & Pienta, K. J. May 11 2016 In : Journal of Visualized Experiments. 2016, 111, e53984

Research output: Research - peer-reviewArticle

Castration
Dissection
Prostate
Microdissection
Testosterone

Nucleolin Staining May Aid in the Identification of Circulating Prostate Cancer Cells

Chalfin, H. J., Verdone, J. E., van der Toom, E. E., Glavaris, S., Gorin, M. A. & Pienta, K. J. Sep 16 2016 (Accepted/In press) In : Clinical Genitourinary Cancer.

Research output: Research - peer-reviewArticle

Circulating Neoplastic Cells
Prostatic Neoplasms
Staining and Labeling
nucleolin
Leukocytes

Oligometastatic prostate cancer: definitions, clinical outcomes, and treatment considerations

Tosoian, J. J., Gorin, M. A., Ross, A. E., Pienta, K. J., Tran, P. T. & Schaeffer, E. M. Oct 11 2016 (Accepted/In press) In : Nature Reviews Urology.

Research output: Research - peer-reviewArticle

Prostatic Neoplasms
Neoplasm Metastasis
Therapeutics
Literature
Poisons
Positron-Emission Tomography
Prostatic Neoplasms
human glutamate carboxypeptidase II
Molecular Imaging
Therapeutics

Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters

Cheung, K. J., Padmanaban, V., Silvestri, V., Schipper, K., Cohen, J. D., Fairchild, A. N., Gorin, M. A., Verdone, J. E., Pienta, K. J., Bader, J. S. & Ewald, A. J. Feb 16 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 7, p. E854-E863

Research output: Research - peer-reviewArticle

Keratin-14
Breast Neoplasms
Neoplasm Metastasis
Neoplasms
Circulating Neoplastic Cells

Prediction of the Pathologic Gleason Score to Inform a Personalized Management Program for Prostate Cancer

Coley, R. Y., Zeger, S. L., Mamawala, M., Pienta, K. J. & Carter, H. B. 2016 (Accepted/In press) In : European Urology.

Research output: Research - peer-reviewArticle

Neoplasm Grading
Prostatic Neoplasms
Prostatectomy
Biopsy
Area Under Curve
Glutamate Carboxypeptidase II
Technetium Tc 99m Medronate
Whole Body Imaging
Bone Neoplasms
Sodium Fluoride

Risk prediction tool for grade re-classification in men with favourable-risk prostate cancer on active surveillance

Mamawala, M. M., Rao, K., Landis, P., Epstein, J. I., Trock, B. J., Tosoian, J. J., Pienta, K. J. & Carter, H. B. 2016 (Accepted/In press) In : BJU International.

Research output: Research - peer-reviewArticle

Prostatic Neoplasms
Odds Ratio
Biopsy
Nomograms
Decision Support Techniques

Role of biobanking in urology: A review

Chalfin, H. J., Fabian, E., Mangold, L., Yeater, D. B., Pienta, K. J. & Partin, A. W. 2016 (Accepted/In press) In : BJU International.

Research output: Research - peer-reviewArticle

Urology
Diagnostic Test Approval
Precision Medicine
Translational Medical Research
Ethics

Stability of the hybrid epithelial/mesenchymal phenotype

Jolly, M. K., Tripathi, S. C., Jia, D., Mooney, S. M., Celiktas, M., Hanash, S. M., Mani, S. A., Pienta, K. J., Ben-Jacob, E. & Levine, H. May 10 2016 In : Oncotarget. 7, 19, p. 27067-27084 18 p.

Research output: Research - peer-reviewArticle

Epithelial-Mesenchymal Transition
Phenotype
Neoplasms
Epithelial Cells
Circulating Neoplastic Cells
2015

Aerobic glycolysis, motility, and cytoskeletal remodeling

Verdone, J. E., Zarif, J. C. & Pienta, K. J. Jan 15 2015 In : Cell cycle (Georgetown, Tex.). 14, 2, p. 169-170 2 p.

Research output: Research - peer-reviewArticle

Epithelial-Mesenchymal Transition
Neoplastic Stem Cells
Glycolysis
Tumor Cell Line
Cytoskeleton

Alternative CD44 splicing identifies epithelial prostate cancer cells from the mesenchymal counterparts

Hernandez, J. R., Kim, J. J., Verdone, J. E., Liu, X., Torga, G., Pienta, K. J. & Mooney, S. M. May 1 2015 In : Medical Oncology. 32, 5, p. 1-9 9 p.

Research output: Research - peer-reviewArticle

Alternative Splicing
Prostatic Neoplasms
Epithelial-Mesenchymal Transition
Flow Cytometry
Western Blotting

A phase 3 trial of 2 years of androgen suppression and radiation therapy with or without adjuvant chemotherapy for high-risk prostate cancer: Final results of radiation therapy oncology group phase 3 randomized trial NRG oncology RTOG 9902

Rosenthal, S. A. , Hunt, D. , Sartor, A. O. , Pienta, K. J. , Gomella, L. , Grignon, D. , Rajan, R. , Kerlin, K. J. , Jones, C. U. , Dobelbower, M. , Shipley, W. U. , Zeitzer, K. , Hamstra, D. A. , Donavanik, V. , Rotman, M. , Hartford, A. C. , Michalski, J. , Seider, M. , Kim, H. , Kuban, D. A. & 2 others Moughan, J. & Sandler, H. Oct 1 2015 In : International Journal of Radiation Oncology, Biology, Physics. 93, 2, p. 294-302 9 p.

Research output: Research - peer-reviewArticle

Radiation Oncology
Adjuvant Chemotherapy
Androgens
Prostatic Neoplasms
Radiotherapy

Beyond immune checkpoint blockade: New approaches to targeting host-tumor interactions in prostate cancer: Report from the 2014 Coffey-Holden Prostate Cancer Academy Meeting

Miyahira, A. K., Kissick, H. T., Bishop, J. L., Takeda, D. Y., Barbieri, C. E., Simons, J. W., Pienta, K. J. & Soule, H. R. Mar 1 2015 In : Prostate. 75, 4, p. 337-347 11 p.

Research output: Research - peer-reviewArticle

Prostatic Neoplasms
Neoplasms
Immunotherapy
Tumor Microenvironment
Therapeutics

Bone marrow macrophages support prostate cancer growth in bone

Soki, F. N., Cho, S. W., Kim, Y. W., Jones, J. D., Park, S. I., Koh, A. J., Entezami, P., Daignault-Newton, S., Pienta, K. J., Roca, H. & McCauley, L. K. 2015 In : Oncotarget. 6, 34, p. 35782-35796 15 p.

Research output: Research - peer-reviewArticle

Bone Development
Prostatic Neoplasms
Bone Marrow
Macrophages
Bone and Bones