Kellie Smith

Instructor

20132018
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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HIV-1 Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Cytotoxic T-Lymphocytes Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Immunotherapy Medicine & Life Sciences
Dendritic Cells Medicine & Life Sciences
Epitopes Medicine & Life Sciences
Non-Small Cell Lung Carcinoma Medicine & Life Sciences

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Research Output 2013 2018

Neoadjuvant PD-1 blockade in resectable lung cancer

Forde, P. M. , Chaft, J. E. , Smith, K. N. , Anagnostou, V. , Cottrell, T. R. , Hellmann, M. D. , Zahurak, M. , Broderick, S. , Yang, S. C. , Jones, D. R. , Battafarano, R. J. , Velez, M. J. , Rekhtman, N. , Olah, Z. , Verde, F. , Naidoo, J. , Marrone, K. A. , Guo, H. , Sidhom, J. W. , Zhang, J. & 15 others Caushi, J. X., Chan, H. Y., Scharpf, R. B., White, J., Gabrielson, E., Wang, H., Rosner, G. L., Rusch, V., Wolchok, J. D., Merghoub, T., Taube, J. M., Velculescu, V. E., Topalian, S. L., Brahmer, J. R. & Pardoll, D. M. May 24 2018 In : New England Journal of Medicine. 378, 21, p. 1976-1986 11 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Clone Cells
Neoplasms
Non-Small Cell Lung Carcinoma
T-Lymphocytes

Evolution of neoantigen landscape during immune checkpoint blockade in non-small cell lung cancer

Anagnostou, V. , Smith, K. N. , Forde, P. M. , Niknafs, N. , Bhattacharya, R. , White, J. , Zhang, T. , Adleff, V. , Phallen, J. , Wali, N. , Hruban, C. , Guthrie, V. B. , Rodgers, K. , Naidoo, J. , Kang, H. , Sharfman, W. , Georgiades, C. , Verde, F. , Illei, P. , Li, Q. K. & 9 others Gabrielson, E., Brock, M. V., Zahnow, C. A., Baylin, S. B., Scharpf, R. B., Brahmer, J. R., Karchin, R., Pardoll, D. M. & Velculescu, V. E. Mar 1 2017 In : Cancer Discovery. 7, 3, p. 264-276 13 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Neoplasms
T-Lymphocytes
Mutation
T-Cell Antigen Receptor

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

Le, D. T. , Durham, J. N. , Smith, K. N. , Wang, H. , Bartlett, B. R. , Aulakh, L. K. , Lu, S. , Kemberling, H. , Wilt, C. , Luber, B. S. , Wong, F. , Azad, N. S. , Rucki, A. A. , Laheru, D. , Donehower, R. , Zaheer, A. , Fisher, G. A. , Crocenzi, T. S. , Lee, J. J. , Greten, T. F. & 26 others Duffy, A. G., Ciombor, K. K., Eyring, A. D., Lam, B. H., Joe, A., Kang, S. P., Holdhoff, M., Danilova, L., Cope, L., Meyer, C., Zhou, S., Goldberg, R. M., Armstrong, D. K., Bever, K. M., Fader, A. N., Taube, J., Housseau, F., Spetzler, D., Xiao, N., Pardoll, D. M., Papadopoulos, N., Kinzler, K. W., Eshleman, J. R., Vogelstein, B., Anders, R. A. & Diaz, L. A. Jul 28 2017 In : Science. 357, 6349, p. 409-413 5 p.

Research output: Contribution to journalArticle

Death Domain Receptors
DNA Mismatch Repair
Neoplasms
Disease-Free Survival
Turcot syndrome

Quantifying the anti-tumor immune response in patients receiving immunotherapy

Caushi, J. X. & Smith, K. N. 2017 In : Discovery Medicine. 24, 130, p. 59-68 10 p.

Research output: Contribution to journalArticle

Immunotherapy
Neoplasms
Therapeutics
Biomarkers
Population

Effective cytotoxic T lymphocyte targeting of persistent HIV-1 during antiretroviral therapy requires priming of naive CD8+ T cells

Smith, K. N., Mailliard, R. B., Piazza, P. A., Fischer, W., Korber, B. T., Fecek, R. J., Ratner, D., Gupta, P., Mullins, J. I. & Rinaldob, C. R. 2016 In : mBio. 7, 3, e00473-16

Research output: Contribution to journalArticle

Cytotoxic T-Lymphocytes
HIV-1
T-Lymphocytes
Dendritic Cells
Therapeutics