Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

HIV-1 Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Cytotoxic T-Lymphocytes Medicine & Life Sciences
Immunotherapy Medicine & Life Sciences
Dendritic Cells Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Epitopes Medicine & Life Sciences
Death Domain Receptors Medicine & Life Sciences

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Research Output 2013 2017

Evolution of neoantigen landscape during immune checkpoint blockade in non-small cell lung cancer

Anagnostou, V. , Smith, K. N. , Forde, P. M. , Niknafs, N. , Bhattacharya, R. , White, J. , Zhang, T. , Adleff, V. , Phallen, J. , Wali, N. , Hruban, C. , Guthrie, V. B. , Rodgers, K. , Naidoo, J. , Kang, H. , Sharfman, W. , Georgiades, C. , Verde, F. , Illei, P. , Li, Q. K. & 9 others Gabrielson, E., Brock, M. V., Zahnow, C. A., Baylin, S. B., Scharpf, R. B., Brahmer, J. R., Karchin, R., Pardoll, D. M. & Velculescu, V. E. Mar 1 2017 In : Cancer Discovery. 7, 3, p. 264-276 13 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Neoplasms
T-Lymphocytes
Mutation
T-Cell Antigen Receptor

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

Le, D. T. , Durham, J. N. , Smith, K. N. , Wang, H. , Bartlett, B. R. , Aulakh, L. K. , Lu, S. , Kemberling, H. , Wilt, C. , Luber, B. S. , Wong, F. , Azad, N. S. , Rucki, A. A. , Laheru, D. , Donehower, R. , Zaheer, A. , Fisher, G. A. , Crocenzi, T. S. , Lee, J. J. , Greten, T. F. & 26 others Duffy, A. G., Ciombor, K. K., Eyring, A. D., Lam, B. H., Joe, A., Kang, S. P., Holdhoff, M., Danilova, L., Cope, L., Meyer, C., Zhou, S., Goldberg, R. M., Armstrong, D. K., Bever, K. M., Fader, A. N., Taube, J., Housseau, F., Spetzler, D., Xiao, N., Pardoll, D. M., Papadopoulos, N., Kinzler, K. W., Eshleman, J. R., Vogelstein, B., Anders, R. A. & Diaz, L. A. Jul 28 2017 In : Science. 357, 6349, p. 409-413 5 p.

Research output: Contribution to journalArticle

Death Domain Receptors
DNA Mismatch Repair
Neoplasms
Disease-Free Survival
Turcot syndrome

Quantifying the anti-tumor immune response in patients receiving immunotherapy

Caushi, J. X. & Smith, K. N. 2017 In : Discovery Medicine. 24, 130, p. 59-68 10 p.

Research output: Contribution to journalArticle

Immunotherapy
Neoplasms
Therapeutics
Biomarkers
Population

Effective cytotoxic T lymphocyte targeting of persistent HIV-1 during antiretroviral therapy requires priming of naive CD8+ T cells

Smith, K. N., Mailliard, R. B., Piazza, P. A., Fischer, W., Korber, B. T., Fecek, R. J., Ratner, D., Gupta, P., Mullins, J. I. & Rinaldob, C. R. 2016 In : mBio. 7, 3, e00473-16

Research output: Contribution to journalArticle

Cytotoxic T-Lymphocytes
HIV-1
T-Lymphocytes
Dendritic Cells
Therapeutics

Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis

Housseau, F., Wu, S., Wick, E. C., Fan, H., Wu, X., Llosa, N. J., Smith, K. N., Tam, A., Ganguly, S., Wanyiri, J. W., Iyadorai, T., Malik, A. A., Roslani, A. C., Vadivelu, J. S., Van Meerbeke, S., Huso, D. L., Pardoll, D. M. & Sears, C. L. Apr 15 2016 In : Cancer Research. 76, 8, p. 2115-2124 10 p.

Research output: Contribution to journalArticle

Th17 Cells
Colon
Carcinogenesis
Bacteroides fragilis
T-Lymphocytes