Keith Pratz

Associate Professor

20052018
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Research Output 2005 2018

Phase 1 study of quizartinib in combination with induction and consolidation chemotherapy in patients with newly diagnosed acute myeloid leukemia

Altman, J. K., Foran, J. M., Pratz, K. W., Trone, D., Cortes, J. E. & Tallman, M. S. Feb 1 2018 In : American Journal of Hematology. 93, 2, p. 213-221 9 p.

Research output: Contribution to journalArticle

Consolidation Chemotherapy
Induction Chemotherapy
Acute Myeloid Leukemia
Standard of Care
Drug Therapy

Safety and preliminary efficacy of venetoclax with decitabine or azacitidine in elderly patients with previously untreated acute myeloid leukaemia: a non-randomised, open-label, phase 1b study

DiNardo, C. D., Pratz, K. W., Letai, A., Jonas, B. A., Wei, A. H., Thirman, M., Arellano, M., Frattini, M. G., Kantarjian, H., Popovic, R., Chyla, B., Xu, T., Dunbar, M., Agarwal, S. K., Humerickhouse, R., Mabry, M., Potluri, J., Konopleva, M. & Pollyea, D. A. Feb 1 2018 In : The Lancet Oncology. 19, 2, p. 216-228 13 p.

Research output: Contribution to journalArticle

decitabine
Azacitidine
Acute Myeloid Leukemia
Safety
4-(4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-((tetrahydro-2H-pyran-4-ylmethyl)amino)phenyl)sulfonyl)-2-(1H-pyrrolo(2,3-b)pyridin-5-yloxy)benzamide

Acute myeloid leukemia, version 3.2017: Clinical practice guidelines in oncology

O'Donnell, M. R. , Tallman, M. S. , Abboud, C. N. , Altman, J. K. , Appelbaum, F. R. , Arber, D. A. , Bhatt, V. , Bixby, D. , Blum, W. , Coutre, S. E. , De Lima, M. , Fathi, A. T. , Fiorella, M. , Foran, J. M. , Gore, S. D. , Hall, A. C. , Kropf, P. , Lancet, J. , Maness, L. J. , Marcucci, G. & 14 others Martin, M. G., Moore, J. O., Olin, R., Peker, D., Pollyea, D. A., Pratz, K., Ravandi, F., Shami, P. J., Stone, R. M., Strickland, S. A., Wang, E. S., Wieduwilt, M., Gregory, K. & Ogba, N. Jul 1 2017 In : JNCCN Journal of the National Comprehensive Cancer Network. 15, 7, p. 926-957 32 p.

Research output: Contribution to journalReview article

Practice Guidelines
Acute Myeloid Leukemia
Leukemia
Guidelines
Therapeutics

Acute myeloid leukemia in the elderly: therapeutic options and choice

Webster, J. A. & Pratz, K. W. Jun 2 2017 (Accepted/In press) In : Leukemia and Lymphoma. p. 1-14 14 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Therapeutics
Comorbidity
Age Groups
Transplants

Adaptation to TKI treatment reactivates ERK signaling in tyrosine kinase–driven leukemias and other malignancies

Bruner, J. K., Ma, H. S., Li, L., Qin, A. C. R., Rudek, M. A., Jones, R. J., Levis, M. J., Pratz, K. W., Pratilas, C. A. & Small, D. Oct 15 2017 In : Cancer Research. 77, 20, p. 5554-5563 10 p.

Research output: Contribution to journalArticle

Protein-Tyrosine Kinases
Leukemia
Neoplasms
Acute Myeloid Leukemia
Mitogen-Activated Protein Kinase Kinases