Justin T Lessler

Associate Professor

20022019
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Research Output 2002 2019

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Article
2019
Decision Trees
beta-Lactamases
Bacteremia
Infection
Pharmaceutical Preparations

Cholera prevention and control in refugee settings: Successes and continued challenges

Shannon, K., Hast, M., Azman, A., Legros, D., McKay, H. & Lessler, J. T., Jun 1 2019, In : PLoS neglected tropical diseases. 13, 6, p. e0007347

Research output: Contribution to journalArticle

Open Access
Refugees
Cholera
Open Access
Motor Vehicles
Health Status
Public Health
Obesity
Smoking

Differential mobility and local variation in infection attack rate

Haw, D. J., Cummings, D. A. T., Lessler, J. T., Salje, H., Read, J. M. & Riley, S., Jan 1 2019, In : PLoS Computational Biology. 15, 1, p. e1006600

Research output: Contribution to journalArticle

Population Density
Infection
population density
Attack
Incidence

Estimating cholera incidence with cross-sectional serology

Azman, A., Lessler, J. T., Luquero, F. J., Bhuiyan, T. R., Khan, A. I., Chowdhury, F., Kabir, A., Gurwith, M., Weil, A. A., Harris, J. B., Calderwood, S. B., Ryan, E. T., Qadri, F. & Leung, D. T., Jan 1 2019, In : Science translational medicine. 11, 480, aau6242.

Research output: Contribution to journalArticle

Cholera
Serology
Vibrio cholerae O1
Incidence
Area Under Curve

Improved inference of time-varying reproduction numbers during infectious disease outbreaks

Thompson, R. N., Stockwin, J. E., van Gaalen, R. D., Polonsky, J. A., Kamvar, Z. N., Demarsh, P. A., Dahlqwist, E., Li, S., Miguel, E., Jombart, T., Lessler, J., Cauchemez, S. & Cori, A., Jan 1 2019, (Accepted/In press) In : Epidemics. 100356.

Research output: Contribution to journalArticle

Open Access
Disease Outbreaks
Reproduction
Ebola Hemorrhagic Fever
Coronavirus Infections
Infectious Disease Transmission

Mapping vaccination coverage to explore the effects of delivery mechanisms and inform vaccination strategies

Utazi, C. E., Thorley, J., Alegana, V. A., Ferrari, M. J., Takahashi, S., Metcalf, C. J. E., Lessler, J. T., Cutts, F. T. & Tatem, A. J., Dec 1 2019, In : Nature communications. 10, 1, 1633.

Research output: Contribution to journalArticle

Open Access
vaccines
Immunization
delivery
Vaccination
Vaccines

Measles and the canonical path to elimination

Graham, M., Winter, A. K., Ferrari, M., Grenfell, B., Moss, W. J., Azman, A., Metcalf, C. J. E. & Lessler, J. T., Jan 1 2019, In : Science. 364, 6440, p. 584-587 4 p.

Research output: Contribution to journalArticle

Open Access
Measles
Disease Outbreaks
Vaccination
Epidemiology
Demography

Perfect counterfactuals for epidemic simulations

Kaminsky, J., Keegan, L. T., Jessica E Metcalf, C. & Lessler, J. T., Jan 1 2019, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 374, 1776, 20180279.

Research output: Contribution to journalArticle

Animals
Disease Outbreaks
infectious diseases
prunes
Uncertainty

Risk factors for household vector abundance using indoor CDC light traps in a high malaria transmission area of Northern Zambia

Hast, M. A., Stevenson, J. C., Muleba, M., Chaponda, M., Kabuya, J. B., Mulenga, M., Lessler, J. T., Shields, T. M., Moss, W. J. & Norris, D., Jan 1 2019, In : American Journal of Tropical Medicine and Hygiene. 101, 1, p. 126-136 11 p.

Research output: Contribution to journalArticle

Zambia
Centers for Disease Control and Prevention (U.S.)
Malaria
Anopheles
Anopheles gambiae

Surveillance and the global fight against cholera: Setting priorities and tracking progress

Azman, A., Moore, S. M. & Lessler, J. T., Jan 1 2019, In : Vaccine.

Research output: Contribution to journalArticle

Open Access
cholera
Vibrio cholerae
Cholera
Vaccines
vaccines

The use of GPS data loggers to describe the impact of spatio-temporal movement patterns on malaria control in a high-transmission area of northern Zambia

Hast, M., Searle, K. M., Chaponda, M., Lupiya, J., Lubinda, J., Sikalima, J., Kobayashi, T., Shields, T. M., Mulenga, M., Lessler, J. T. & Moss, W. J., Aug 19 2019, In : International Journal of Health Geographics. 18, 1, 19.

Research output: Contribution to journalArticle

Open Access
Malaria control
Zambia
Malaria
Global positioning system
Spraying
2018

A spatial regression model for the disaggregation of areal unit based data to high-resolution grids with application to vaccination coverage mapping

Utazi, C. E., Thorley, J., Alegana, V. A., Ferrari, M. J., Nilsen, K., Takahashi, S., Metcalf, C. J. E., Lessler, J. T. & Tatem, A. J., Jan 1 2018, (Accepted/In press) In : Statistical Methods in Medical Research.

Research output: Contribution to journalArticle

Disaggregation
Vaccination
Spatial Model
Regression Model
Coverage

Benefits and challenges in using seroprevalence data to inform models for measles and rubella elimination

Winter, A. K., Martinez, M. E., Cutts, F. T., Moss, W. J., Ferrari, M. J., Mckee, A., Lessler, J. T., Hayford, K., Wallinga, J. & Metcalf, C. J. E., Jul 2 2018, In : Journal of Infectious Diseases. 218, 3, p. 355-364 10 p.

Research output: Contribution to journalArticle

Rubella
Seroepidemiologic Studies
Measles
Immunity
Disease Eradication

Challenges and opportunities in disease forecasting in outbreak settings: A case study of measles in Lola Prefecture, Guinea

Graham, M., Suk, J. E., Takahashi, S., Jessica Metcalf, C., Paez Jimenez, A., Prikazsky, V., Ferrari, M. J. & Lessler, J. T., Jan 1 2018, In : American Journal of Tropical Medicine and Hygiene. 98, 5, p. 1489-1497 9 p.

Research output: Contribution to journalArticle

Guinea
Measles
Disease Outbreaks
Uncertainty
Immunization Programs

Characterizing the impact of spatial clustering of susceptibility for measles elimination

Truelove, S. A., Graham, M., Moss, W. J., Metcalf, C. J. E., Ferrari, M. J. & Lessler, J. T., Jan 1 2018, (Accepted/In press) In : Vaccine.

Research output: Contribution to journalArticle

Measles
Cluster Analysis
Vaccination
vaccination
Population

Contact tracing performance during the Ebola epidemic in Liberia, 2014-2015

Swanson, K. C., Altare, C., Wesseh, C. S., Nyenswah, T., Ahmed, T., Eyal, N., Hamblion, E. L., Lessler, J., Peters, D. H. & Altmann, M., Sep 1 2018, In : PLoS Neglected Tropical Diseases. 12, 9, e0006762.

Research output: Contribution to journalArticle

Liberia
Contact Tracing
Ebola Hemorrhagic Fever
Logistic Models
Contact Dermatitis

High resolution age-structured mapping of childhood vaccination coverage in low and middle income countries

Utazi, C. E., Thorley, J., Alegana, V. A., Ferrari, M. J., Takahashi, S., Metcalf, C. J. E., Lessler, J. T. & Tatem, A. J., Mar 14 2018, In : Vaccine. 36, 12, p. 1583-1591 9 p.

Research output: Contribution to journalArticle

childhood
Vaccination
income
vaccination
Measles

Mapping the burden of cholera in sub-Saharan Africa and implications for control: an analysis of data across geographical scales

Lessler, J. T., Moore, S. M., Luquero, F. J., McKay, H., Grais, R., Henkens, M., Mengel, M., Dunoyer, J., M'bangombe, M., Lee, E. C., Djingarey, M. H., Sudre, B., Bompangue, D., Fraser, R. S. M., Abubakar, A., Perea, W., Legros, D. & Azman, A., Jan 1 2018, (Accepted/In press) In : The Lancet.

Research output: Contribution to journalArticle

Africa South of the Sahara
Cholera
Incidence
Djibouti
Eritrea

Micro-hotspots of risk in urban cholera epidemics

Azman, A., Luquero, F. J., Salje, H., Mbaïbardoum, N. N., Adalbert, N., Ali, M., Bertuzzo, E., Finger, F., Toure, B., Massing, L. A., Ramazani, R., Saga, B., Allan, M., Olson, D., Leglise, J., Porten, K. & Lessler, J. T., Jan 1 2018, In : Journal of Infectious Diseases. 218, 7, p. 1164-1168 5 p.

Research output: Contribution to journalArticle

Cholera
Chad
Democratic Republic of the Congo

Quantifying the Risk and Cost of Active Monitoring for Infectious Diseases

Reich, N. G., Lessler, J. T., Varma, J. K. & Vora, N. M., Dec 1 2018, In : Scientific Reports. 8, 1, 1093.

Research output: Contribution to journalArticle

Communicable Diseases
Costs and Cost Analysis
Smallpox
Disease Outbreaks
Public Health

Reconstruction of antibody dynamics and infection histories to evaluate dengue risk

Salje, H., Cummings, D. A. T., Rodriguez-Barraquer, I., Katzelnick, L. C., Lessler, J. T., Klungthong, C., Thaisomboonsuk, B., Nisalak, A., Weg, A., Ellison, D., Macareo, L., Yoon, I. K., Jarman, R., Thomas, S., Rothman, A. L., Endy, T. & Cauchemez, S., May 31 2018, In : Nature. 557, 7707, p. 719-723 5 p.

Research output: Contribution to journalArticle

Dengue
Asymptomatic Infections
Antibodies
Infection
Confidence Intervals

Revealing Measles Outbreak Risk with a Nested Immunoglobulin G Serosurvey in Madagascar

Winter, A. K., Wesolowski, A., Mensah, K. J., Ramamonjiharisoa, M. B., Randriamanantena, A. H., Razafindratsimandresy, R., Cauchemez, S., Lessler, J. T., Ferrari, M. J., Metcalf, C. J. E. & Héraud, J. M., Oct 1 2018, In : American Journal of Epidemiology. 187, 10, p. 2219-2226 8 p.

Research output: Contribution to journalArticle

Madagascar
Measles
Disease Outbreaks
Immunoglobulin G
Immunity

The epidemiology of cholera in Zanzibar: Implications for the zanzibar comprehensive cholera elimination plan

Bi, Q., Abdalla, F. M., Masauni, S., Reyburn, R., Msambazi, M., Deglise, C., Von Seidlein, L., Deen, J., Jiddawi, M. S., Olson, D., Nemes, I., Taib, J. A., Lessler, J. T., Andemichael, G. R. & Azman, A., Oct 15 2018, In : Journal of Infectious Diseases. 218, p. S173-S180

Research output: Contribution to journalArticle

Tanzania
Cholera
Epidemiology
Disease Outbreaks
Incidence

The potential impact of case-area targeted interventions in response to cholera outbreaks: A modeling study

Finger, F., Bertuzzo, E., Luquero, F. J., Naibei, N., Touré, B., Allan, M., Porten, K., Lessler, J. T., Rinaldo, A. & Azman, A., Feb 1 2018, In : PLoS Medicine. 15, 2, e1002509.

Research output: Contribution to journalArticle

Cholera
Disease Outbreaks
Cholera Vaccines
Water Purification
Anti-Bacterial Agents

Timescales of influenza A/H3N2 antibody dynamics

Kucharski, A. J., Lessler, J. T., Cummings, D. A. T. & Riley, S., Aug 20 2018, In : PLoS Biology. 16, 8, e2004974.

Research output: Contribution to journalArticle

influenza
Human Influenza
antibodies
Antibodies
Infection

Vacuna oral contra el cólera para la prevención y el control del cólera, Malawi

Translated title of the contribution: Oral cholera vaccine in cholera prevention and control, MalawiM’Bangombe, M., Pezzoli, L., Reeder, B., Kabuluzi, S., Msyamboza, K., Masuku, H., Ngwira, B., Cavailler, P., Grandesso, F., Palomares, A., Beck, N., Shaffer, A., MacDonald, E., Senbete, M., Lessler, J. T., Moore, S. M. & Azman, A., Jun 1 2018, In : Bulletin of the World Health Organization. 96, 6, p. 428-436 9 p.

Research output: Contribution to journalArticle

Cholera Vaccines
Malawi
Cholera
Sanitation
Disease Outbreaks
2017

Bacterial Infections in Neonates Following Mupirocin-Based MRSA Decolonization: A Multicenter Cohort Study

Pierce, R., Bryant, K., Elward, A., Lessler, J. T. & Milstone, A., Aug 1 2017, In : Infection Control and Hospital Epidemiology. 38, 8, p. 930-936 7 p.

Research output: Contribution to journalArticle

Mupirocin
Methicillin-Resistant Staphylococcus aureus
Bacterial Infections
Multicenter Studies
Cohort Studies

Cohort Profile: A study of influenza immunity in the urban and rural Guangzhou region of China: the Fluscape Study

Jiang, C. Q., Lessler, J. T., Kim, L., Kwok, K. O., Read, J. M., Wang, S., Tan, L., Hast, M., Zhu, H., Guan, Y., Riley, S. & Cummings, D. A., Apr 1 2017, In : International Journal of Epidemiology. 46, 2, p. e16

Research output: Contribution to journalArticle

cohort analysis
influenza
health survey
vaccination
histology

Demographics, epidemiology and the impact of vaccination campaigns in a measles-free world – Can elimination be maintained?

Prada, J. M., Metcalf, C. J. E., Takahashi, S., Lessler, J. T., Tatem, A. J. & Ferrari, M., Mar 13 2017, In : Vaccine. 35, 11, p. 1488-1493 6 p.

Research output: Contribution to journalArticle

Immunization Programs
Measles
epidemiology
Immunization
immunization

Dengue diversity across spatial and temporal scales: Local structure and the effect of host population size

Salje, H., Lessler, J. T., Berry, I. M., Melendrez, M. C., Endy, T., Kalayanarooj, S., A-Nuegoonpipat, A., Chanama, S., Sangkijporn, S., Klungthong, C., Thaisomboonsuk, B., Nisalak, A., Gibbons, R. V., Iamsirithaworn, S., MacAreo, L. R., Yoon, I. K., Sangarsang, A., Jarman, R. G. & Cummings, D. A. T., Mar 24 2017, In : Science. 355, 6331, p. 1302-1306 5 p.

Research output: Contribution to journalArticle

Dengue
Population Density
Thailand
Genotype
Population

El Niño and the shifting geography of cholera in Africa

Moore, S. M., Azman, A., Zaitchik, B. F., Mintz, E. D., Brunkard, J., Legros, D., Hill, A., McKay, H., Luquero, F. J., Olson, D. & Lessler, J. T., Apr 25 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 17, p. 4436-4441 6 p.

Research output: Contribution to journalArticle

Geography
Cholera
Eastern Africa
Incidence
Southern Africa

High hepatitis e seroprevalence among displaced persons in South Sudan

Azman, A., Bouhenia, M., Iyer, A. S., Rumunu, J., Laku, R. L., Wamala, J. F., Rodriguez-Barraquer, I., Lessler, J. T., Gignoux, E., Luquero, F. J., Leung, D. T., Gurley, E. & Ciglenecki, I., 2017, In : American Journal of Tropical Medicine and Hygiene. 96, 6, p. 1296-1301 6 p.

Research output: Contribution to journalArticle

Hepatitis E virus
Seroepidemiologic Studies
Hepatitis
Immunoglobulin G
Virus Diseases

HIV prevention efforts and incidence of HIV in Uganda

Grabowski, M. K., Serwadda, D. M., Gray, R. H., Nakigozi, G., Kigozi, G., Kagaayi, J., Ssekubugu, R., Nalugoda, F., Lessler, J., Lutalo, T., Galiwango, R. M., Makumbi, F., Kong, X., Kabatesi, D., Alamo, S. T., Wiersma, S., Sewankambo, N. K., Tobian, A. A. R., Laeyendecker, O., Quinn, T. C. & 3 others, Reynolds, S. J., Wawer, M. J. & Chang, L. W., Nov 30 2017, In : New England Journal of Medicine. 377, 22, p. 2154-2166 13 p.

Research output: Contribution to journalArticle

Uganda
HIV
Incidence
Virus Diseases
Male Circumcision

Impact of interventions and the incidence of ebola virus disease in Liberia - Implications for future epidemics

Kirsch, T. D., Moseson, H., Massaquoi, M., Nyenswah, T. G., Goodermote, R., Rodriguez-Barraquer, I., Lessler, J., Cumings, D. A. T. & Peters, D. H., 2017, In : Health Policy and Planning. 32, 2, p. 205-214 10 p.

Research output: Contribution to journalArticle

Ebola Hemorrhagic Fever
Liberia
Incidence
United Nations
United States Agency for International Development
Methicillin
Neonatal Intensive Care Units
Staphylococcus aureus
Confidence Intervals
Pressure

Protection against cholera from killed whole-cell oral cholera vaccines: A systematic review and meta-analysis

Bi, Q., Ferreras, E., Pezzoli, L., Legros, D., Ivers, L. C., Date, K., Qadri, F., Digilio, L., Sack, D. A., Ali, M., Lessler, J. T., Luquero, F. J. & Azman, A., 2017, (Accepted/In press) In : The Lancet Infectious Diseases.

Research output: Contribution to journalArticle

Cholera Vaccines
Cholera
Meta-Analysis
Vaccines
Observational Studies

Rubella vaccination in India: identifying broad consequences of vaccine introduction and key knowledge gaps

WINTER, A. K., PRAMANIK, S., Lessler, J. T., FERRARI, M., GRENFELL, B. T. & METCALF, C. J. E., Dec 4 2017, (Accepted/In press) In : Epidemiology and Infection. p. 1-13 13 p.

Research output: Contribution to journalArticle

Congenital Rubella Syndrome
Rubella Vaccine
Rubella
India
Vaccination

Simulations for designing and interpreting intervention trials in infectious diseases

Halloran, M. E., Auranen, K., Baird, S., Basta, N. E., Bellan, S. E., Brookmeyer, R., Cooper, B. S., DeGruttola, V., Hughes, J. P., Lessler, J. T., Lofgren, E. T., Longini, I. M., Onnela, J. P., Özler, B., Seage, G. R., Smith, T. A., Vespignani, A., Vynnycky, E. & Lipsitch, M., Dec 29 2017, In : BMC Medicine. 15, 1, 223.

Research output: Contribution to journalArticle

Communicable Diseases
Emerging Communicable Diseases
Population
Epidemiology
Economics

The geography of measles vaccination in the African Great Lakes region

Takahashi, S., Metcalf, C. J. E., Ferrari, M. J., Tatem, A. J. & Lessler, J. T., May 25 2017, In : Nature Communications. 8, 15585.

Research output: Contribution to journalArticle

Great Lakes Region
Great Lakes (North America)
geography
Geography
Measles
2016

A Clinical Decision Tree to Predict Whether a Bacteremic Patient is Infected with an Extended-Spectrum β-Lactamase-Producing Organism

Antibacterial Resistance Leadership Group, Oct 1 2016, In : Clinical Infectious Diseases. 63, 7, p. 896-903 8 p.

Research output: Contribution to journalArticle

Decision Trees
Bacteremia
Anti-Bacterial Agents
Carbapenems
Klebsiella

A comparison of hemagglutination inhibition and neutralization assays for characterizing immunity to seasonal influenza A

Truelove, S., Zhu, H., Lessler, J. T., Riley, S., Read, J. M., Wang, S., Kwok, K. O., Guan, Y., Jiang, C. Q. & Cummings, D. A. T., Nov 1 2016, In : Influenza and other Respiratory Viruses. 10, 6, p. 518-524 7 p.

Research output: Contribution to journalArticle

Hemagglutination
Human Influenza
Immunity
Orthomyxoviridae
Serum

Case Study in Evaluating Time Series Prediction Models Using the Relative Mean Absolute Error

Reich, N. G., Lessler, J., Sakrejda, K., Lauer, S. A., Iamsirithaworn, S. & Cummings, D. A. T., Jul 2 2016, In : American Statistician. 70, 3, p. 285-292 8 p.

Research output: Contribution to journalArticle

Time Series Prediction
Time Series Models
Prediction Model
Metric
Prediction

Challenges in Real-Time Prediction of Infectious Disease: A Case Study of Dengue in Thailand

Reich, N. G., Lauer, S. A., Sakrejda, K., Iamsirithaworn, S., Hinjoy, S., Suangtho, P., Suthachana, S., Clapham, H. E., Salje, H., Cummings, D. A. T. & Lessler, J. T., Jun 15 2016, In : PLoS Neglected Tropical Diseases. 10, 6, e0004761.

Research output: Contribution to journalArticle

Dengue
Thailand
Communicable Diseases
Public Health
Incidence

Effectiveness of one dose of oral cholera vaccine in response to an outbreak: a case-cohort study

Azman, A., Parker, L. A., Rumunu, J., Tadesse, F., Grandesso, F., Deng, L. L., Lino, R. L., Bior, B. K., Lasuba, M., Page, A. L., Ontweka, L., Llosa, A. E., Cohuet, S., Pezzoli, L., Sodjinou, D. V., Abubakar, A., Debes, A., Mpairwe, A. M., Wamala, J. F., Jamet, C. & 5 others, Lessler, J. T., Sack, D. A., Quilici, M. L., Ciglenecki, I. & Luquero, F. J., Nov 1 2016, In : The Lancet Global Health. 4, 11, p. e856-e863

Research output: Contribution to journalArticle

Cholera Vaccines
Cholera
Disease Outbreaks
Cohort Studies
Vaccines

Estimating infectious disease transmission distances using the overall distribution of cases

Salje, H., Cummings, D. A. T. & Lessler, J. T., Dec 1 2016, In : Epidemics. 17, p. 10-18 9 p.

Research output: Contribution to journalArticle

Infectious Disease Transmission
Contact Tracing
Disease Outbreaks
Mouth
Information Dissemination

Estimating the severity and subclinical burden of middle east respiratory syndrome coronavirus infection in the Kingdom of Saudi Arabia

Lessler, J. T., Salje, H., Van Kerkhove, M. D., Ferguson, N. M., Cauchemez, S., Rodriquez-Barraquer, I., Hakeem, R., Jombart, T., Aguas, R., Al-Barrak, A. & Cummings, D. A. T., Apr 1 2016, In : American Journal of Epidemiology. 183, 7, p. 657-663 7 p.

Research output: Contribution to journalArticle

Coronavirus Infections
Saudi Arabia
Confidence Intervals
Statistical Models
Middle East Respiratory Syndrome Coronavirus

Forty years of dengue surveillance at a tertiary pediatric hospital in Bangkok, Thailand, 1973-2012

Nisalak, A., Clapham, H. E., Kalayanarooj, S., Klungthong, C., Thaisomboonsuk, B., Fernandez, S., Reiser, J., Srikiatkhachorn, A., Macareo, L. R., Lessler, J. T., Cummings, D. A. T. & Yoon, I. K., Jun 1 2016, In : American Journal of Tropical Medicine and Hygiene. 94, 6, p. 1342-1347 6 p.

Research output: Contribution to journalArticle

Pediatric Hospitals
Dengue
Thailand
Dengue Virus
Tertiary Care Centers

Heterogeneity of the HIV epidemic in agrarian, trading, and fishing communities in Rakai, Uganda: an observational epidemiological study

Chang, L., Grabowski, M., Ssekubugu, R., Nalugoda, F., Kigozi, G., Nantume, B., Lessler, J. T., Moore, S. M., Quinn, T. C., Reynolds, S. J., Gray, R. H., Serwadda, D. & Wawer, M. J., Aug 1 2016, In : The Lancet HIV. 3, 8, p. e388-e396

Research output: Contribution to journalArticle

Uganda
Observational Studies
Epidemiologic Studies
HIV
National Institute of Allergy and Infectious Diseases (U.S.)

How social structures, space, and behaviors shape the spread of infectious diseases using chikungunya as a case study

Salje, H., Lessler, J. T., Paul, K. K., Azman, A., Rahman, M. W., Rahman, M., Cummings, D., Gurley, E. & Cauchemez, S., Nov 22 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 47, p. 13420-13425 6 p.

Research output: Contribution to journalArticle

Communicable Diseases
Uncertainty
Disease Outbreaks
Bangladesh
Rural Population