Justin S Hanes


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Nanoparticles Medicine & Life Sciences
Mucus Medicine & Life Sciences
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Pharmaceutical Preparations Medicine & Life Sciences
Genes Engineering & Materials Science
Polymers Medicine & Life Sciences
Microspheres Medicine & Life Sciences
Lung Medicine & Life Sciences

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Research Output 1994 2018

An Adeno-Associated Viral Vector Capable of Penetrating the Mucus Barrier to Inhaled Gene Therapy

Duncan, G. A., Kim, N., Colon-Cortes, Y., Rodriguez, J., Mazur, M., Birket, S. E., Rowe, S. M., West, N. E., Livraghi-Butrico, A., Boucher, R. C., Hanes, J., Aslanidi, G. & Suk, J. S., Jun 15 2018, In : Molecular Therapy - Methods and Clinical Development. 9, p. 296-304 9 p.

Research output: Contribution to journalArticle

Genetic Therapy
Cystic Fibrosis

Development of rectal enema as microbicide (DREAM): Preclinical progressive selection of a tenofovir prodrug enema

Hoang, T., Date, A. A., Ortiz, J. O., Young, T. W., Bensouda, S., Xiao, P., Marzinke, M., Rohan, L., Fuchs, E. J., Hendrix, C., Gumber, S., Villinger, F., Cone, R. A., Hanes, J. & Ensign, L. M., Jan 1 2018, (Accepted/In press) In : European Journal of Pharmaceutics and Biopharmaceutics.

Research output: Contribution to journalArticle

Anti-Infective Agents
Sexual Behavior

Effects of enzymatic degradation on dynamic mechanical properties of the vitreous and intravitreal nanoparticle mobility

Huang, D., Chen, Y. S., Xu, Q., Hanes, J. & Rupenthal, I. D., Jun 15 2018, In : European Journal of Pharmaceutical Sciences. 118, p. 124-133 10 p.

Research output: Contribution to journalArticle

Retinal Diseases
Fluorescence Spectrometry

Fate of PEGylated antibody fragments following delivery to the lungs: Influence of delivery site, PEG size and lung inflammation

Patil, H. P., Freches, D., Karmani, L., Duncan, G. A., Ucakar, B., Suk, J. S., Hanes, J., Gallez, B. & Vanbever, R., Feb 28 2018, In : Journal of Controlled Release. 272, p. 62-71 10 p.

Research output: Contribution to journalArticle

Immunoglobulin Fragments
Immunoglobulin Fab Fragments

Hypo-osmolar formulation of tenofovir (TFV) enema promotes uptake and metabolism of TFV in tissues, leading to prevention of SHIV/SIV infection

Xiao, P., Gumber, S., Marzinke, M. A., Date, A. A., Hoang, T., Hanes, J., Ensign, L. M., Wang, L., Rohan, L., Fuchs, E. J., Hendrix, C. & Villinger, F., Jan 1 2018, In : Antimicrobial Agents and Chemotherapy. 62, 1, e01644-17

Research output: Contribution to journalArticle