Research Output 2004 2017

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2017

Extra-epitopic hepatitis C virus polymorphisms confer resistance to broadly neutralizing antibodies by modulating binding to scavenger receptor B1

El-Diwany, R., Cohen, V. J., Mankowski, M. C., Wasilewski, L. N., Brady, J. K., Snider, A. E., Osburn, W. O., Murrell, B., Ray, S. C. & Bailey, J. R. Feb 1 2017 In : PLoS Pathogens. 13, 2, e1006235

Research output: Research - peer-reviewArticle

Scavenger Receptors
Neutralizing Antibodies
Hepacivirus
difluprednate
Epitopes
2016

Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute hepatitis C virus infection in mice

Keck, Z. Y., Wang, Y., Lau, P., Lund, G., Rangarajan, S., Fauvelle, C., Liao, G. C., Holtsberg, F. W., Warfield, K. L., Aman, M. J., Pierce, B. G., Fuerst, T. R., Bailey, J. R., Baumert, T. F., Mariuzza, R. A., Kneteman, N. M. & Foung, S. K. H. Dec 1 2016 In : Hepatology. 64, 6, p. 1922-1933 12 p.

Research output: Research - peer-reviewArticle

Virus Diseases
Hepacivirus
Monoclonal Antibodies
Antiviral Agents
Antibodies

A hepatitis C virus envelope polymorphism confers resistance to neutralization by polyclonal sera and broadly neutralizing monoclonal antibodies

Wasilewski, L. N., El-Diwany, R., Munshaw, S., Snider, A. E., Brady, J. K., Osburn, W. O., Ray, S. C. & Bailey, J. R. 2016 In : Journal of Virology. 90, 7, p. 3773-3782 10 p.

Research output: Research - peer-reviewArticle

Hepatitis C virus
neutralizing antibodies
neutralization
monoclonal antibodies
genetic polymorphism

Factors Associated With the Control of Viral Replication and Virologic Breakthrough in a Recently Infected HIV-1 Controller

Walker-Sperling, V. E., Pohlmeyer, C. W., Veenhuis, R. T., May, M., Luna, K. A., Kirkpatrick, A. R., Laeyendecker, O., Cox, A. L., Carrington, M., Bailey, J. R., Arduino, R. C. & Blankson, J. N. Jul 6 2016 (Accepted/In press) In : EBioMedicine.

Research output: Research - peer-reviewArticle

HIV-1
T-cells
Viruses
Controllers
Chemical activation

Hepatitis C virus resistance to broadly neutralizing antibodies measured using replication-competent virus and pseudoparticles

Wasilewski, L. N., Ray, S. C. & Bailey, J. R. Nov 1 2016 In : Journal of General Virology. 97, 11, p. 2883-2893 11 p., 000608

Research output: Research - peer-reviewArticle

Virus Replication
Neutralizing Antibodies
Hepacivirus
Proteins
Epitopes
2015
Virus Diseases
MicroRNAs
Hepacivirus
Hepatocytes
Hepatitis C virus
Neutralizing Antibodies
Coinfection
Hepacivirus
Antibody Formation
HIV

Naturally selected hepatitis C virus polymorphisms confer broad neutralizing antibody resistance

Bailey, J. R., Wasilewski, L. N., Snider, A. E., El-Diwany, R., Osburn, W. O., Keck, Z., Foung, S. K. H. & Ray, S. C. Jan 2 2015 In : Journal of Clinical Investigation. 125, 1, p. 437-447 11 p.

Research output: Research - peer-reviewArticle

Neutralizing Antibodies
Hepacivirus
Cluster Analysis
Sequence Analysis
Vaccines
2014

Clearance of hepatitis C infection is associated with the early appearance of broad neutralizing antibody responses

Osburn, W. O., Snider, A. E., Wells, B. L., Latanich, R., Bailey, J. R., Thomas, D. L., Cox, A. L. & Ray, S. C. 2014 In : Hepatology. 59, 6, p. 2140-2151 12 p.

Research output: Research - peer-reviewArticle

Hepatitis C
Neutralizing Antibodies
Antibody Formation
Infection
Genotype
2013

Multi-step inhibition explains HIV-1 protease inhibitor pharmacodynamics and resistance

Rabi, S. A., Laird, G. M., Durand, C. M., Laskey, S., Shan, L., Bailey, J. R., Chioma, S., Moore, R. D. & Siliciano, R. F. Sep 3 2013 In : Journal of Clinical Investigation. 123, 9, p. 3848-3860 13 p.

Research output: Research - peer-reviewArticle

HIV Protease Inhibitors
Protease Inhibitors
Human immunodeficiency virus 1 p16 protease
Life Cycle Stages
Reverse Transcription
2012

Computational reconstruction of bole1a, a representative synthetic hepatitis C virus subtype 1a genome

Munshaw, S., Bailey, J. R., Liu, L., Osburn, W. O., Burke, K. P., Cox, A. L. & Ray, S. C. May 2012 In : Journal of Virology. 86, 10, p. 5915-5921 7 p.

Research output: Research - peer-reviewArticle

Hepatitis C virus
genome
Hepacivirus
Genome
genes

Constraints on viral evolution during chronic hepatitis C virus infection arising from a common-source exposure

Bailey, J. R., Laskey, S., Wasilewski, L. N., Munshaw, S., Fanning, L. J., Kenny-Walsh, E. & Ray, S. C. Dec 2012 In : Journal of Virology. 86, 23, p. 12582-12590 9 p.

Research output: Research - peer-reviewArticle

Chronic Hepatitis C
Virus Diseases
Hepacivirus
Infection
chronic hepatitis C
2011
Highly Active Antiretroviral Therapy
HIV-1
T-Lymphocytes
Viral Load
HIV Infections

Unstimulated primary CD4+ T cells from HIV-1-positive elite suppressors are fully susceptible to HIV-1 entry and productive infection

Rabi, S. A., O'Connell, K. A., Nikolaeva, D., Bailey, J. R., Jilek, B. L., Shen, L., Page, K. R., Siliciano, R. F. & Blankson, J. N. Jan 2011 In : Journal of Virology. 85, 2, p. 979-986 8 p.

Research output: Research - peer-reviewArticle

Human immunodeficiency virus 1
T-lymphocytes
infection
HIV long-term survivors
HIV-1
2010

Control of HIV-1 in elite suppressors despite ongoing replication and evolution in plasma virus

O'Connell, K. A., Brennan, T. P., Bailey, J. R., Ray, S. C., Siliciano, R. F. & Blankson, J. N. Jul 2010 In : Journal of Virology. 84, 14, p. 7018-7028 11 p.

Research output: Research - peer-reviewArticle

Cytotoxic T-Lymphocytes
HIV-1
Viruses
Human immunodeficiency virus 1
viruses

Evolution of the HIV-1 nef gene in HLA-B*57 Positive Elite Suppressors

Salgado, M., Brennan, T. P., O'Connell, K. A., Bailey, J. R., Ray, S. C., Siliciano, R. F. & Blankson, J. N. Nov 8 2010 In : Retrovirology. 7, 94

Research output: Research - peer-reviewArticle

nef Genes
gag Genes
HIV-1
HLA-B57 antigen
Silent Mutation

Raltegravir-induced cerebellar ataxia

Reiss, K. A., Bailey, J. R., Pham, P. A. & Gallant, J. E. Nov 13 2010 In : AIDS. 24, 17, p. 2757 1 p.

Research output: Research - peer-reviewArticle

2009

Elite suppressor-derived hiv-1 envelope glycoproteins exhibit reduced entry efficiency and kinetics

Lassen, K. G., Lobritz, M. A., Bailey, J. R., Johnston, S., Nguyen, S., Lee, B., Chou, T., Siliciano, R. F., Markowitz, M. & Arts, E. J. Apr 2009 In : PLoS Pathogens. 5, 4

Research output: Research - peer-reviewArticle

HIV-1
Glycoproteins
CCR5 Receptors
env Gene Products
Virus Internalization

Elucidating the elite: mechanisms of control in HIV-1 infection

O'Connell, K. A., Bailey, J. R. & Blankson, J. N. Dec 2009 In : Trends in Pharmacological Sciences. 30, 12, p. 631-637 7 p.

Research output: Research - peer-reviewArticle

HIV Infections
HIV-1
T-Lymphocytes
T-cells
Controllers

Evidence of CD8+ T-cell-mediated selective pressure on human immunodeficiency virus type 1 nef in HLA-B*57+ elite suppressors

Bailey, J. R., Brennan, T. P., O'Connell, K. A., Siliciano, R. F. & Blankson, J. N. Jan 2009 In : Journal of Virology. 83, 1, p. 88-97 10 p.

Research output: Research - peer-reviewArticle

Human immunodeficiency virus 1
T-lymphocytes
HIV long-term survivors
HIV-1
T-Lymphocytes
2008
HLA Antigens
Viral Load
HIV-1
T-Lymphocytes
Virus Replication
Viremia
HIV-1
Human immunodeficiency virus 1
HIV long-term survivors
viremia

Transmission of human immunodeficiency virus type 1 from a patient who developed AIDS to an elite suppressor

Bailey, J. R., O'Connell, K., Yang, H. C., Han, Y., Xu, J., Jilek, B., Williams, T. M., Ray, S. C., Siliciano, R. F. & Blankson, J. N. Aug 2008 In : Journal of Virology. 82, 15, p. 7395-7410 16 p.

Research output: Research - peer-reviewArticle

HIV-1
Acquired Immunodeficiency Syndrome
T-Lymphocytes
Human immunodeficiency virus 1
HIV long-term survivors
2007

Evolution of HIV-1 in an HLA-B*57-positive patient during virologic escape

Bailey, J. R., Zhang, H., Wegweiser, B. W., Yang, H. C., Herrera, L., Ahonkhai, A., Williams, T. M., Siliciano, R. F. & Blankson, J. N. Jul 1 2007 In : Journal of Infectious Diseases. 196, 1, p. 50-55 6 p.

Research output: Research - peer-reviewArticle

HIV-1
T-Lymphocytes
Mutation
HLA-B57 antigen
T-Lymphocyte Epitopes

Isolation and characterization of replication-competent human immunodeficiency virus type 1 from a subset of elite suppressors

Blankson, J. N., Bailey, J. R., Thayil, S., Yang, H. C., Lassen, K., Lai, J., Gandhi, S. K., Siliciano, J. D., Williams, T. M. & Siliciano, R. F. Mar 2007 In : Journal of Virology. 81, 5, p. 2508-2518 11 p.

Research output: Research - peer-reviewArticle

Human immunodeficiency virus 1
HIV long-term survivors
HIV-1
Genes
viruses
2006

Crosscurrents in HIV-1 evolution

Blankson, J. N., Bailey, J. R. & Siliciano, R. F. Feb 2006 In : Nature Immunology. 7, 2, p. 121-122 2 p.

Research output: Research - peer-reviewArticle

T-Lymphocyte Epitopes
Viral Proteins
HIV-1
Epitopes
Immunity
HIV-1
Epitopes
Maintenance
Mutation
HLA-B57 antigen
Human immunodeficiency virus 1
neutralizing antibodies
viruses
therapeutics
HIV long-term survivors

Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells.

Lassen, K. G., Ramyar, K. X., Bailey, J. R., Zhou, Y. & Siliciano, R. F. Jul 2006 In : PLoS Pathogens. 2, 7

Research output: Research - peer-reviewArticle

HIV-1
RNA
T-Lymphocytes
Polypyrimidine Tract-Binding Protein
Highly Active Antiretroviral Therapy

Planning for the HPV vaccine and its impact on cervical cancer prevention

Bailey, J. & Cymet, T. C. 2006 In : Comprehensive Therapy. 32, 2, p. 102-105 4 p.

Research output: Research - peer-reviewArticle

Papillomaviridae
Papillomavirus Vaccines
Uterine Cervical Neoplasms
Neoplasms
Penile Neoplasms

Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4+ T cells

Bailey, J. R., Sedaghat, A. R., Kieffer, T., Brennan, T., Lee, P. K., Wind-Rotolo, M., Haggerty, C. M., Kamireddi, A. R., Liu, Y., Lee, J., Persaud, D., Gallant, J. E., Cofrancesco, J., Quinn, T. C., Wilke, C. O., Ray, S. C., Siliciano, J. D., Nettles, R. E. & Siliciano, R. F. Jul 2006 In : Journal of Virology. 80, 13, p. 6441-6457 17 p.

Research output: Research - peer-reviewArticle

viremia
Human immunodeficiency virus 1
T-lymphocytes
clones
viruses
2004

Analysis of human immunodeficiency virus type 1 transcriptional elongation in resting CD4+ T cells in vivo

Lassen, K. G., Bailey, J. R. & Siliciano, R. F. Sep 2004 In : Journal of Virology. 78, 17, p. 9105-9114 10 p.

Research output: Research - peer-reviewArticle

HIV-1
T-Lymphocytes
Human immunodeficiency virus 1
T-lymphocytes
therapeutics
Glycogen Synthase Kinase 3
Protein Precursors
Capsid Proteins
Cytomegalovirus
Phosphorylation

Mechanisms of HIV-1 escape from immune responses and antiretroviral drugs

Bailey, J., Blankson, J. N., Wind-Rotolo, M. & Siliciano, R. F. Aug 2004 In : Current Opinion in Immunology. 16, 4, p. 470-476 7 p.

Research output: Research - peer-reviewArticle

HIV-1
Pharmaceutical Preparations
B-Lymphocyte Epitopes
T-Lymphocyte Epitopes
Drug Combinations