Justin Bailey

Associate Professor

20042020

Research output per year

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Research Output

Article

Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute hepatitis C virus infection in mice

Keck, Z. Y., Wang, Y., Lau, P., Lund, G., Rangarajan, S., Fauvelle, C., Liao, G. C., Holtsberg, F. W., Warfield, K. L., Aman, M. J., Pierce, B. G., Fuerst, T. R., Bailey, J., Baumert, T. F., Mariuzza, R. A., Kneteman, N. M. & Foung, S. K. H., Dec 1 2016, In : Hepatology. 64, 6, p. 1922-1933 12 p.

Research output: Contribution to journalArticle

A hepatitis C virus envelope polymorphism confers resistance to neutralization by polyclonal sera and broadly neutralizing monoclonal antibodies

Wasilewski, L. N., El-Diwany, R., Munshaw, S., Snider, A. E., Brady, J. K., Osburn, W. O., Ray, S. C. & Bailey, J. R., Jan 1 2016, In : Journal of virology. 90, 7, p. 3773-3782 10 p.

Research output: Contribution to journalArticle

Analysis of human immunodeficiency virus type 1 transcriptional elongation in resting CD4+ T cells in vivo

Lassen, K. G., Bailey, J. R. & Siliciano, R. F., Sep 1 2004, In : Journal of virology. 78, 17, p. 9105-9114 10 p.

Research output: Contribution to journalArticle

An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein

Flyak, A. I., Ruiz, S. E., Salas, J., Rho, S., Bailey, J. R. & Bjorkman, P. J., Mar 2020, In : eLife. 9, e53169.

Research output: Contribution to journalArticle

Open Access

Approaches, Progress, and Challenges to Hepatitis C Vaccine Development

Bailey, J., Barnes, E. & Cox, A., Jan 1 2019, In : Gastroenterology. 156, 2, p. 418-430 13 p.

Research output: Contribution to journalArticle

Broadly Neutralizing Antibodies Targeting New Sites of Vulnerability in Hepatitis C Virus E1E2

Colbert, M. D., Flyak, A. I., Ogega, C. O., Kinchen, V. J., Massaccesi, G., Hernandez, M., Davidson, E., Doranz, B. J., Cox, A. L., Crowe, J. E. & Bailey, J. R., Jul 15 2019, In : Journal of virology. 93, 14

Research output: Contribution to journalArticle

Broadly neutralizing antibodies with few somatic mutations and hepatitis C virus clearance

Bailey, J. R., Flyak, A. I., Cohen, V. J., Li, H., Wasilewski, L. N., Snider, A. E., Wang, S., Learn, G. H., Kose, N., Loerinc, L., Lampley, R., Cox, A. L., Pfaff, J. M., Doranz, B. J., Shaw, G. M., Ray, S. C. & Crowe, J. E., May 4 2017, In : JCI Insight. 2, 9

Research output: Contribution to journalArticle

Open Access

Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection

Kinchen, V. J., Zahid, M. N., Flyak, A. I., Soliman, M. G., Learn, G. H., Wang, S., Davidson, E., Doranz, B. J., Ray, S. C., Cox, A. L., Crowe, J. E., Bjorkman, P. J., Shaw, G. M. & Bailey, J. R., Nov 14 2018, In : Cell Host and Microbe. 24, 5, p. 717-730.e5

Research output: Contribution to journalArticle

Can Broadly Neutralizing Monoclonal Antibodies Lead to a Hepatitis C Virus Vaccine?

Kinchen, V. J., Cox, A. & Bailey, J., Jan 1 2018, (Accepted/In press) In : Trends in Microbiology.

Research output: Contribution to journalArticle

Clearance of hepatitis C infection is associated with the early appearance of broad neutralizing antibody responses

Osburn, W. O., Snider, A. E., Wells, B. L., Latanich, R., Bailey, J. R., Thomas, D. L., Cox, A. L. & Ray, S. C., Jun 2014, In : Hepatology. 59, 6, p. 2140-2151 12 p.

Research output: Contribution to journalArticle

CMPK2 and BCL-G are associated with type 1 interferon–induced HIV restriction in humans

El-Diwany, R., Soliman, M., Sugawara, S., Breitwieser, F., Skaist, A., Coggiano, C., Sangal, N., Chattergoon, M. A., Bailey, J., Siliciano, R. F., Blankson, J. N., Ray, S. C., Wheelan, S., Thomas, D. L. & Balagopal, A., Aug 1 2018, In : Science advances. 4, 8, eaat0843.

Research output: Contribution to journalArticle

Computational reconstruction of bole1a, a representative synthetic hepatitis C virus subtype 1a genome

Munshaw, S., Bailey, J. R., Liu, L., Osburn, W. O., Burke, K. P., Cox, A. L. & Ray, S. C., May 1 2012, In : Journal of virology. 86, 10, p. 5915-5921 7 p.

Research output: Contribution to journalArticle

Constraints on viral evolution during chronic hepatitis C virus infection arising from a common-source exposure

Bailey, J. R., Laskey, S., Wasilewski, L. N., Munshaw, S., Fanning, L. J., Kenny-Walsh, E. & Ray, S. C., Dec 1 2012, In : Journal of virology. 86, 23, p. 12582-12590 9 p.

Research output: Contribution to journalArticle

Control of HIV-1 in elite suppressors despite ongoing replication and evolution in plasma virus

O'Connell, K. A., Brennan, T. P., Bailey, J. R., Ray, S. C., Siliciano, R. F. & Blankson, J. N., Jul 1 2010, In : Journal of virology. 84, 14, p. 7018-7028 11 p.

Research output: Contribution to journalArticle

Elite suppressor-derived hiv-1 envelope glycoproteins exhibit reduced entry efficiency and kinetics

Lassen, K. G., Lobritz, M. A., Bailey, J. R., Johnston, S., Nguyen, S., Lee, B., Chou, T., Siliciano, R. F., Markowitz, M. & Arts, E. J., Apr 1 2009, In : PLoS pathogens. 5, 4

Research output: Contribution to journalArticle

Evidence of CD8+ T-cell-mediated selective pressure on human immunodeficiency virus type 1 nef in HLA-B*57+ elite suppressors

Bailey, J. R., Brennan, T. P., O'Connell, K. A., Siliciano, R. F. & Blankson, J. N., Jan 1 2009, In : Journal of virology. 83, 1, p. 88-97 10 p.

Research output: Contribution to journalArticle

Evolution of HIV-1 in an HLA-B*57-positive patient during virologic escape

Bailey, J. R., Zhang, H., Wegweiser, B. W., Yang, H. C., Herrera, L., Ahonkhai, A., Williams, T. M., Siliciano, R. F. & Blankson, J. N., Jul 1 2007, In : Journal of Infectious Diseases. 196, 1, p. 50-55 6 p.

Research output: Contribution to journalArticle

Evolution of the HIV-1 nef gene in HLA-B*57 Positive Elite Suppressors

Salgado, M., Brennan, T. P., O'Connell, K. A., Bailey, J. R., Ray, S. C., Siliciano, R. F. & Blankson, J. N., Nov 8 2010, In : Retrovirology. 7, 94.

Research output: Contribution to journalArticle

Extra-epitopic hepatitis C virus polymorphisms confer resistance to broadly neutralizing antibodies by modulating binding to scavenger receptor B1

El-Diwany, R., Cohen, V. J., Mankowski, M. C., Wasilewski, L. N., Brady, J. K., Snider, A. E., Osburn, W., Murrell, B., Ray, S. C. & Bailey, J., Feb 1 2017, In : PLoS Pathogens. 13, 2, e1006235.

Research output: Contribution to journalArticle

Factors Associated With the Control of Viral Replication and Virologic Breakthrough in a Recently Infected HIV-1 Controller

Walker-Sperling, V. E., Pohlmeyer, C. W., Terilli Veenhuis, R., May, M., Luna, K. A., Kirkpatrick, A. R., Laeyendecker, O. B., Cox, A., Carrington, M., Bailey, J., Arduino, R. C. & Blankson, J. N., Jul 6 2016, (Accepted/In press) In : EBioMedicine.

Research output: Contribution to journalArticle

HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design

Flyak, A. I., Ruiz, S., Colbert, M. D., Luong, T., Crowe, J. E., Bailey, J. R. & Bjorkman, P. J., Nov 14 2018, In : Cell Host and Microbe. 24, 5, p. 703-716.e3

Research output: Contribution to journalArticle

Hepatitis C virus resistance to broadly neutralizing antibodies measured using replication-competent virus and pseudoparticles

Wasilewski, L. N., Ray, S. C. & Bailey, J., Nov 1 2016, In : Journal of General Virology. 97, 11, p. 2883-2893 11 p., 000608.

Research output: Contribution to journalArticle

Isolation and characterization of replication-competent human immunodeficiency virus type 1 from a subset of elite suppressors

Blankson, J. N., Bailey, J. R., Thayil, S., Yang, H. C., Lassen, K., Lai, J., Gandhi, S. K., Siliciano, J. D., Williams, T. M. & Siliciano, R. F., Mar 1 2007, In : Journal of virology. 81, 5, p. 2508-2518 11 p.

Research output: Contribution to journalArticle

Long-term remission despite clonal expansion of replication-competent HIV-1 isolates

Terilli Veenhuis, R., Kwaa, A. K., Garliss, C. C., Latanich, R., Salgado, M., Pohlmeyer, C. W., Nobles, C. L., Gregg, J., Scully, E., Bailey, J., Bushman, F. D. & Blankson, J. N., Sep 20 2018, In : JCI insight. 3, 18

Research output: Contribution to journalArticle

Open Access

Multi-step inhibition explains HIV-1 protease inhibitor pharmacodynamics and resistance

Rabi, S. A., Laird, G. M., Durand, C. M., Laskey, S., Shan, L., Bailey, J. R., Chioma, S., Moore, R. D. & Siliciano, R. F., Sep 3 2013, In : Journal of Clinical Investigation. 123, 9, p. 3848-3860 13 p.

Research output: Contribution to journalArticle

Naturally selected hepatitis C virus polymorphisms confer broad neutralizing antibody resistance

Bailey, J. R., Wasilewski, L. N., Snider, A. E., El-Diwany, R., Osburn, W. O., Keck, Z., Foung, S. K. H. & Ray, S. C., Jan 2 2015, In : Journal of Clinical Investigation. 125, 1, p. 437-447 11 p.

Research output: Contribution to journalArticle

No recovery of replication-competent HIV-1 from human liver macrophages

Kandathil, A., Sugawara, S., Goyal, A., Durand, C., Quinn, J., Sachithanandham, J., Cameron, A. M., Bailey, J., Perelson, A. S. & Balagopal, A., Oct 1 2018, In : Journal of Clinical Investigation. 128, 10, p. 4501-4509 9 p.

Research output: Contribution to journalArticle

Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells

Lassen, K. G., Ramyar, K. X., Bailey, J. R., Zhou, Y. & Siliciano, R. F., Aug 4 2006, In : PLoS pathogens. 2, 7, p. 650-661 12 p.

Research output: Contribution to journalArticle

Planning for the HPV vaccine and its impact on cervical cancer prevention

Bailey, J. & Cymet, T. C., Aug 1 2006, In : Comprehensive therapy. 32, 2, p. 102-105 4 p.

Research output: Contribution to journalArticle

Plasma deconvolution identifies broadly neutralizing antibodies associated with hepatitis C virus clearance

Kinchen, V. J., Massaccesi, G., Flyak, A. I., Mankowski, M. C., Colbert, M. D., Osburn, W. O., Ray, S. C., Cox, A. L., Crowe, J. E. & Bailey, J. R., Aug 13 2019, In : The Journal of clinical investigation. 130

Research output: Contribution to journalArticle

Open Access

Prolonged control of replication-competent dual- tropic human immunodeficiency virus-1 following cessation of highly active antiretroviral therapy.

Salgado, M., Rabi, S. A., O'Connell, K. A., Buckheit, R. W., Bailey, J. R., Chaudhry, A. A., Breaud, A. R., Marzinke, M. A., Clarke, W., Margolick, J. B., Siliciano, R. F. & Blankson, J. N., Dec 1 2011, In : Retrovirology. 8, 1 p.

Research output: Contribution to journalArticle

Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4+ T cells

Bailey, J. R., Sedaghat, A. R., Kieffer, T., Brennan, T., Lee, P. K., Wind-Rotolo, M., Haggerty, C. M., Kamireddi, A. R., Liu, Y., Lee, J., Persaud, D., Gallant, J. E., Cofrancesco, J., Quinn, T. C., Wilke, C. O., Ray, S. C., Siliciano, J. D., Nettles, R. E. & Siliciano, R. F., Jul 1 2006, In : Journal of virology. 80, 13, p. 6441-6457 17 p.

Research output: Contribution to journalArticle

Synergistic anti-HCV broadly neutralizing human monoclonal antibodies with independent mechanisms

Mankowski, M. C., Kinchen, V. J., Wasilewski, L. N., Flyak, A. I., Ray, S. C., Crowe, J. E. & Bailey, J. R., Jan 2 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 1, p. E82-E91

Research output: Contribution to journalArticle

Transmission of human immunodeficiency virus type 1 from a patient who developed AIDS to an elite suppressor

Bailey, J. R., O'Connell, K., Yang, H. C., Han, Y., Xu, J., Jilek, B., Williams, T. M., Ray, S. C., Siliciano, R. F. & Blankson, J. N., Aug 1 2008, In : Journal of virology. 82, 15, p. 7395-7410 16 p.

Research output: Contribution to journalArticle

Unstimulated primary CD4+ T cells from HIV-1-positive elite suppressors are fully susceptible to HIV-1 entry and productive infection

Rabi, S. A., O'Connell, K. A., Nikolaeva, D., Bailey, J. R., Jilek, B. L., Shen, L., Page, K. R., Siliciano, R. F. & Blankson, J. N., Jan 1 2011, In : Journal of virology. 85, 2, p. 979-986 8 p.

Research output: Contribution to journalArticle

Chapter

Hepatitis C virus

Ray, S. C., Bailey, J. & Thomas, D. L., May 21 2013, Fields Virology: Sixth Edition. Wolters Kluwer Health Adis (ESP), Vol. 1.

Research output: Chapter in Book/Report/Conference proceedingChapter

Standardized method for the study of antibody neutralization of HCV pseudoparticles (HCVpp)

Bailey, J., Urbanowicz, R. A., Ball, J. K., Law, M. & Foung, S. K. H., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 441-450 10 p. (Methods in Molecular Biology; vol. 1911).

Research output: Chapter in Book/Report/Conference proceedingChapter

Comment/debate

Crosscurrents in HIV-1 evolution

Blankson, J. N., Bailey, J. R. & Siliciano, R. F., Feb 1 2006, In : Nature Immunology. 7, 2, p. 121-122 2 p.

Research output: Contribution to journalComment/debate

Editorial

Broadly neutralizing antibodies against hepatitis C virus: location, location, location

Skinner, N. E. & Bailey, J. R., Jan 1 2020, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalEditorial

Open Access
Letter

Raltegravir-induced cerebellar ataxia

Reiss, K. A., Bailey, J. R., Pham, P. A. & Gallant, J. E., Nov 13 2010, In : AIDS. 24, 17, 1 p.

Research output: Contribution to journalLetter

Review article

Defining breadth of hepatitis C virus neutralization

Kinchen, V. J. & Bailey, J., Aug 2 2018, In : Frontiers in Immunology. 9, AUG, 1703.

Research output: Contribution to journalReview article