Research Output 2004 2018

2018

Can Broadly Neutralizing Monoclonal Antibodies Lead to a Hepatitis C Virus Vaccine?

Kinchen, V. J., Cox, A. L. & Bailey, J. R. Jan 1 2018 (Accepted/In press) In : Trends in Microbiology.

Research output: Contribution to journalArticle

Neutralizing Antibodies
Hepacivirus
Vaccines
Monoclonal Antibodies
Virus Diseases

Synergistic anti-HCV broadly neutralizing human monoclonal antibodies with independent mechanisms

Mankowski, M. C., Kinchen, V. J., Wasilewski, L. N., Flyak, A. I., Ray, S. C., Crowe, J. E. & Bailey, J. R. Jan 2 2018 In : Proceedings of the National Academy of Sciences of the United States of America. 115, 1, p. E82-E91

Research output: Contribution to journalArticle

Neutralizing Antibodies
Hepacivirus
Monoclonal Antibodies
Vaccines
Genotype
2017

Extra-epitopic hepatitis C virus polymorphisms confer resistance to broadly neutralizing antibodies by modulating binding to scavenger receptor B1

El-Diwany, R., Cohen, V. J., Mankowski, M. C., Wasilewski, L. N., Brady, J. K., Snider, A. E., Osburn, W. O., Murrell, B., Ray, S. C. & Bailey, J. R. Feb 1 2017 In : PLoS Pathogens. 13, 2, e1006235

Research output: Contribution to journalArticle

Scavenger Receptors
Neutralizing Antibodies
Hepacivirus
Epitopes
Monoclonal Antibodies
2016

Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute hepatitis C virus infection in mice

Keck, Z. Y., Wang, Y., Lau, P., Lund, G., Rangarajan, S., Fauvelle, C., Liao, G. C., Holtsberg, F. W., Warfield, K. L., Aman, M. J., Pierce, B. G., Fuerst, T. R., Bailey, J. R., Baumert, T. F., Mariuzza, R. A., Kneteman, N. M. & Foung, S. K. H. Dec 1 2016 In : Hepatology. 64, 6, p. 1922-1933 12 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepacivirus
Monoclonal Antibodies
Antiviral Agents
Hepatovirus

A hepatitis C virus envelope polymorphism confers resistance to neutralization by polyclonal sera and broadly neutralizing monoclonal antibodies

Wasilewski, L. N., El-Diwany, R., Munshaw, S., Snider, A. E., Brady, J. K., Osburn, W. O., Ray, S. C. & Bailey, J. R. 2016 In : Journal of Virology. 90, 7, p. 3773-3782 10 p.

Research output: Contribution to journalArticle

Hepatitis C virus
Neutralizing Antibodies
neutralizing antibodies
neutralization
Hepacivirus

Factors Associated With the Control of Viral Replication and Virologic Breakthrough in a Recently Infected HIV-1 Controller

Walker-Sperling, V. E., Pohlmeyer, C. W., Veenhuis, R. T., May, M., Luna, K. A., Kirkpatrick, A. R., Laeyendecker, O., Cox, A. L., Carrington, M., Bailey, J. R., Arduino, R. C. & Blankson, J. N. Jul 6 2016 (Accepted/In press) In : EBioMedicine.

Research output: Contribution to journalArticle

T-cells
Viruses
HIV-1
Controllers
Natural Killer Cells

Hepatitis C virus resistance to broadly neutralizing antibodies measured using replication-competent virus and pseudoparticles

Wasilewski, L. N., Ray, S. C. & Bailey, J. R. Nov 1 2016 In : Journal of General Virology. 97, 11, p. 2883-2893 11 p., 000608

Research output: Contribution to journalArticle

Virus Replication
Neutralizing Antibodies
Hepacivirus
Proteins
Epitopes
2015
Hepatitis C virus
Virus Diseases
MicroRNAs
microRNA
Hepacivirus
Neutralizing Antibodies
Coinfection
Hepacivirus
Antibody Formation
HIV

Naturally selected hepatitis C virus polymorphisms confer broad neutralizing antibody resistance

Bailey, J. R., Wasilewski, L. N., Snider, A. E., El-Diwany, R., Osburn, W. O., Keck, Z., Foung, S. K. H. & Ray, S. C. Jan 2 2015 In : Journal of Clinical Investigation. 125, 1, p. 437-447 11 p.

Research output: Contribution to journalArticle

Neutralizing Antibodies
Hepacivirus
Cluster Analysis
Sequence Analysis
Vaccines
2014

Clearance of hepatitis C infection is associated with the early appearance of broad neutralizing antibody responses

Osburn, W. O., Snider, A. E., Wells, B. L., Latanich, R., Bailey, J. R., Thomas, D. L., Cox, A. L. & Ray, S. C. 2014 In : Hepatology. 59, 6, p. 2140-2151 12 p.

Research output: Contribution to journalArticle

Hepatitis C
Neutralizing Antibodies
Antibody Formation
Genotype
Virus Diseases
2013

Hepatitis C virus

Ray, S. C., Bailey, J. R. & Thomas, D. L. May 21 2013 Fields Virology: Sixth Edition. Wolters Kluwer Health Adis (ESP), Vol. 1

Research output: Chapter in Book/Report/Conference proceedingChapter

Hepacivirus

Multi-step inhibition explains HIV-1 protease inhibitor pharmacodynamics and resistance

Rabi, S. A., Laird, G. M., Durand, C. M., Laskey, S., Shan, L., Bailey, J. R., Chioma, S., Moore, R. D. & Siliciano, R. F. Sep 3 2013 In : Journal of Clinical Investigation. 123, 9, p. 3848-3860 13 p.

Research output: Contribution to journalArticle

HIV Protease Inhibitors
Protease Inhibitors
Life Cycle Stages
Reverse Transcription
env Gene Products
2012

Computational reconstruction of bole1a, a representative synthetic hepatitis C virus subtype 1a genome

Munshaw, S., Bailey, J. R., Liu, L., Osburn, W. O., Burke, K. P., Cox, A. L. & Ray, S. C. May 2012 In : Journal of Virology. 86, 10, p. 5915-5921 7 p.

Research output: Contribution to journalArticle

Hepatitis C virus
Hepacivirus
Genome
genome
epitopes

Constraints on viral evolution during chronic hepatitis C virus infection arising from a common-source exposure

Bailey, J. R., Laskey, S., Wasilewski, L. N., Munshaw, S., Fanning, L. J., Kenny-Walsh, E. & Ray, S. C. Dec 2012 In : Journal of Virology. 86, 23, p. 12582-12590 9 p.

Research output: Contribution to journalArticle

chronic hepatitis C
Hepatitis C virus
Chronic Hepatitis C
Virus Diseases
Hepacivirus
2011
Highly Active Antiretroviral Therapy
HIV-1
Viral Load
T-Lymphocytes
HIV Infections

Unstimulated primary CD4+ T cells from HIV-1-positive elite suppressors are fully susceptible to HIV-1 entry and productive infection

Rabi, S. A., O'Connell, K. A., Nikolaeva, D., Bailey, J. R., Jilek, B. L., Shen, L., Page, K. R., Siliciano, R. F. & Blankson, J. N. Jan 2011 In : Journal of Virology. 85, 2, p. 979-986 8 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus 1
HIV-1
T-lymphocytes
T-Lymphocytes
Infection
2010

Control of HIV-1 in elite suppressors despite ongoing replication and evolution in plasma virus

O'Connell, K. A., Brennan, T. P., Bailey, J. R., Ray, S. C., Siliciano, R. F. & Blankson, J. N. Jul 2010 In : Journal of Virology. 84, 14, p. 7018-7028 11 p.

Research output: Contribution to journalArticle

Cytotoxic T-Lymphocytes
Human immunodeficiency virus 1
HIV-1
Viremia
cytotoxic T-lymphocytes

Evolution of the HIV-1 nef gene in HLA-B*57 Positive Elite Suppressors

Salgado, M., Brennan, T. P., O'Connell, K. A., Bailey, J. R., Ray, S. C., Siliciano, R. F. & Blankson, J. N. Nov 8 2010 In : Retrovirology. 7, 94

Research output: Contribution to journalArticle

nef Genes
gag Genes
HIV-1
Viral Load
Epitopes

Raltegravir-induced cerebellar ataxia

Reiss, K. A., Bailey, J. R., Pham, P. A. & Gallant, J. E. Nov 13 2010 In : AIDS. 24, 17, p. 2757 1 p.

Research output: Contribution to journalArticle

Pyridazines
Pyrrolidinones
Cerebellar Ataxia
HIV Infections
HIV-1
2009

Elite suppressor-derived hiv-1 envelope glycoproteins exhibit reduced entry efficiency and kinetics

Lassen, K. G., Lobritz, M. A., Bailey, J. R., Johnston, S., Nguyen, S., Lee, B., Chou, T., Siliciano, R. F., Markowitz, M. & Arts, E. J. Apr 2009 In : PLoS Pathogens. 5, 4

Research output: Contribution to journalArticle

HIV-1
Glycoproteins
CCR5 Receptors
env Gene Products
Virus Internalization

Elucidating the elite: mechanisms of control in HIV-1 infection

O'Connell, K. A., Bailey, J. R. & Blankson, J. N. Dec 2009 In : Trends in Pharmacological Sciences. 30, 12, p. 631-637 7 p.

Research output: Contribution to journalArticle

T-cells
HIV Infections
HIV-1
T-Lymphocytes
Controllers

Evidence of CD8+ T-cell-mediated selective pressure on human immunodeficiency virus type 1 nef in HLA-B*57+ elite suppressors

Bailey, J. R., Brennan, T. P., O'Connell, K. A., Siliciano, R. F. & Blankson, J. N. Jan 2009 In : Journal of Virology. 83, 1, p. 88-97 10 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus 1
HIV-1
T-lymphocytes
T-Lymphocytes
Viruses
2008
HLA Antigens
Viral Load
HIV-1
T-Lymphocytes
Virus Replication
Viremia
Human immunodeficiency virus 1
HIV-1
viremia
Cytidine Deaminase

Transmission of human immunodeficiency virus type 1 from a patient who developed AIDS to an elite suppressor

Bailey, J. R., O'Connell, K., Yang, H. C., Han, Y., Xu, J., Jilek, B., Williams, T. M., Ray, S. C., Siliciano, R. F. & Blankson, J. N. Aug 2008 In : Journal of Virology. 82, 15, p. 7395-7410 16 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus 1
HIV-1
Acquired Immunodeficiency Syndrome
T-Lymphocytes
T-lymphocytes
2007

Evolution of HIV-1 in an HLA-B*57-positive patient during virologic escape

Bailey, J. R., Zhang, H., Wegweiser, B. W., Yang, H. C., Herrera, L., Ahonkhai, A., Williams, T. M., Siliciano, R. F. & Blankson, J. N. Jul 1 2007 In : Journal of Infectious Diseases. 196, 1, p. 50-55 6 p.

Research output: Contribution to journalArticle

HIV-1
T-Lymphocytes
Mutation
T-Lymphocyte Epitopes
Viral Load

Isolation and characterization of replication-competent human immunodeficiency virus type 1 from a subset of elite suppressors

Blankson, J. N., Bailey, J. R., Thayil, S., Yang, H. C., Lassen, K., Lai, J., Gandhi, S. K., Siliciano, J. D., Williams, T. M. & Siliciano, R. F. Mar 2007 In : Journal of Virology. 81, 5, p. 2508-2518 11 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus 1
HIV-1
INDEL Mutation
Defective Viruses
Viremia
2006

Crosscurrents in HIV-1 evolution

Blankson, J. N., Bailey, J. R. & Siliciano, R. F. Feb 2006 In : Nature Immunology. 7, 2, p. 121-122 2 p.

Research output: Contribution to journalArticle

T-Lymphocyte Epitopes
Viral Proteins
HIV-1
Epitopes
Immunity
HIV-1
Epitopes
Maintenance
Mutation
Viruses
Highly Active Antiretroviral Therapy
Human immunodeficiency virus 1
Neutralizing Antibodies
neutralizing antibodies
HIV-1

Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells.

Lassen, K. G., Ramyar, K. X., Bailey, J. R., Zhou, Y. & Siliciano, R. F. Jul 2006 In : PLoS Pathogens. 2, 7

Research output: Contribution to journalArticle

Polypyrimidine Tract-Binding Protein
HIV-1
RNA
Highly Active Antiretroviral Therapy
T-Lymphocytes

Planning for the HPV vaccine and its impact on cervical cancer prevention

Bailey, J. & Cymet, T. C. 2006 In : Comprehensive Therapy. 32, 2, p. 102-105 4 p.

Research output: Contribution to journalArticle

Papillomaviridae
Papillomavirus Vaccines
Uterine Cervical Neoplasms
Penile Neoplasms
Asymptomatic Infections

Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4+ T cells

Bailey, J. R., Sedaghat, A. R., Kieffer, T., Brennan, T., Lee, P. K., Wind-Rotolo, M., Haggerty, C. M., Kamireddi, A. R., Liu, Y., Lee, J., Persaud, D., Gallant, J. E., Cofrancesco, J., Quinn, T. C., Wilke, C. O., Ray, S. C., Siliciano, J. D., Nettles, R. E. & Siliciano, R. F. Jul 2006 In : Journal of Virology. 80, 13, p. 6441-6457 17 p.

Research output: Contribution to journalArticle

Viremia
viremia
Human immunodeficiency virus 1
HIV-1
Clone Cells
2004

Analysis of human immunodeficiency virus type 1 transcriptional elongation in resting CD4+ T cells in vivo

Lassen, K. G., Bailey, J. R. & Siliciano, R. F. Sep 2004 In : Journal of Virology. 78, 17, p. 9105-9114 10 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus 1
HIV-1
T-lymphocytes
T-Lymphocytes
Highly Active Antiretroviral Therapy
Glycogen Synthase Kinase 3
Cytomegalovirus
Protein Precursors
Capsid Proteins
coat proteins

Mechanisms of HIV-1 escape from immune responses and antiretroviral drugs

Bailey, J., Blankson, J. N., Wind-Rotolo, M. & Siliciano, R. F. Aug 2004 In : Current Opinion in Immunology. 16, 4, p. 470-476 7 p.

Research output: Contribution to journalArticle

HIV-1
B-Lymphocyte Epitopes
T-Lymphocyte Epitopes
Drug Combinations
Pharmaceutical Preparations