Jun Yang

Research output

Research output per year 2007 2020 2021 2022 2023

• 29 Article
• 2 Comment/debate
• 1 Letter
• 1 Review article

Research output per year

Research output per year

Search results

• 2023

  Insulin-like growth factor binding Protein-4: A novel indicator of pulmonary arterial hypertension severity and survival

  Torres, G., Yang, J., Griffiths, M., Brandal, S., Damico, R., Vaidya, D., Simpson, C. E., Pauciulo, M. W., Nichols, W. C., Ivy, D. D., Austin, E. D., Hassoun, P. M. & Everett, A. D., Apr 2023, In: Pulmonary Circulation. 13, 2, e12235.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Insulin-Like Growth Factor Binding Protein 4 100%
  • Pulmonary Arterial Hypertension 76%
  • Survival 36%
  • Somatomedins 19%
  • Cohort Studies 12%

• Low-affinity insulin-like growth factor binding protein 7 and its association with pulmonary arterial hypertension severity and survival

  Torres, G., Lancaster, A. C., Yang, J., Griffiths, M., Brandal, S., Damico, R., Vaidya, D., Simpson, C. E., Martin, L. J., Pauciulo, M. W., Nichols, W. C., Ivy, D. D., Austin, E. D., Hassoun, P. M. & Everett, A. D., Jul 2023, In: Pulmonary Circulation. 13, 3, e12284.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • insulin-like growth factor binding protein-related protein 1 100%
  • Pulmonary Arterial Hypertension 69%
  • Carrier Proteins 49%
  • Survival 32%
  • Insulin-Like Growth Factor Binding Proteins 25%

• Parkinson's disease fluid biomarkers for differential diagnosis of atypical parkinsonian syndromes

  Yang, J., Idowu, A., Rosenthal, L. & Mao, X., Feb 2023, In: Clinical and Translational Discovery. 3, 1, e150.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Parkinsonian Disorders 100%
  • Parkinson Disease, Familial, Type 1 82%
  • Biological Marker 82%
  • Parkinson Disease 76%
  • Differential Diagnosis 70%
• 2022

  Biomarkers of Pulmonary Hypertension Are Altered in Children with Down Syndrome and Pulmonary Hypertension

  Griffiths, M., Yang, J., Vaidya, D., Nies, M., Brandal, S., Ivy, D. D., Hickey, F., Wolter-Warmerdam, K., Austin, E. D., Mullen, M., Pauciulo, M. W., Lutz, K. A., Rosenzweig, E. B., Hirsch, R., Yung, D., Nichols, W. C. & Everett, A. D., Feb 2022, In: Journal of Pediatrics. 241, p. 68-76.e3

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Down Syndrome 100%
  • Pulmonary Hypertension 95%
  • Biomarkers 62%
  • Child 41%
  • Galectin 3 19%

• Cellular sources of interleukin-6 and associations with clinical phenotypes and outcomes in pulmonary arterial hypertension

  Simpson, C. E., Chen, J. Y., Damico, R. L., Hassoun, P. M., Martin, L. J., Yang, J., Nies, M., Griffiths, M., Vaidya, D., Brandal, S., Pauciulo, M. W., Lutz, K. A., Coleman, A. W., Austin, E. D., Ivy, D. D., Nichols, W. C. & Everett, A. D., Apr 1 2022, In: European Respiratory Journal. 59, 4, 1901761.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pulmonary Arterial Hypertension 100%
  • Interleukin-6 65%
  • Phenotype 51%
  • Pulmonary Artery 15%
  • Smooth Muscle Myocytes 14%

• COL18A1 genotypic associations with endostatin levels and clinical features in pulmonary arterial hypertension: a quantitative trait association study

  Simpson, C. E., Griffiths, M., Yang, J., Nies, M. K., Vaidya, D., Brandal, S., Martin, L. J., Pauciulo, M. W., Lutz, K. A., Coleman, A. W., Austin, E. D., Ivy, D. D., Nichols, W. C., Everett, A. D., Hassoun, P. M. & Damico, R. L., Apr 1 2022, In: ERJ Open Research. 8, 2, 00725-2021.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

• Galectin-4 as a Novel Biomarker of Neonatal Intestinal Injury

  Fundora, J. B., Zhu, J., Yanek, L. R., Go, M., Shakeel, F., Brooks, S. S., Yang, J., Hackam, D. J., Everett, A. D. & Shores, D. R., Mar 2022, In: Digestive diseases and sciences. 67, 3, p. 863-871 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Galectin 4 100%
  • Biomarkers 35%
  • Necrotizing Enterocolitis 27%
  • Spontaneous Perforation 26%
  • Wounds and Injuries 26%

• Hepatoma-derived growth factor is associated with pulmonary vascular remodeling and PAH disease severity and survival

  Yang, J., Ambade, A. S., Nies, M., Griffiths, M., Damico, R., Vaidya, D., Brandal, S., Pauciulo, M. W., Lutz, K. A., Coleman, A. W., Nichols, W. C., Austin, E. D., Ivy, D., Hassoun, P. M. & Everett, A. D., Jan 2022, In: Pulmonary Circulation. 12, 1, e12007.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • hepatoma-derived growth factor 100%
  • Vascular Remodeling 65%
  • Pulmonary Arterial Hypertension 65%
  • Survival 30%
  • Lung 29%

• Proteomics discovery of pulmonary hypertension biomarkers: Insulin-like growth factor binding proteins are associated with disease severity

  Nies, M. K., Yang, J., Griffiths, M., Damico, R., Zhu, J., Vaydia, D., Fu, Z., Brandal, S., Austin, E. D., Ivy, D. D., Hassoun, P. M., Van Eyk, J. E. & Everett, A. D., Apr 2022, In: Pulmonary Circulation. 12, 2, e12039.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Insulin-Like Growth Factor Binding Proteins 100%
  • Pulmonary Arterial Hypertension 89%
  • Pulmonary Hypertension 75%
  • Proteomics 70%
  • Biomarkers 49%
• 2021

  Angiostatic peptide, endostatin, predicts severity in pediatric congenital heart disease–associated pulmonary hypertension

  Daly, C. M., Griffiths, M., Simpson, C. E., Yang, J., Damico, R. L., Vaidya, R. D., Williams, M., Brandal, S., Jone, P. N., Polsen, C., Ivy, D. D., Austin, E. D., Nichols, W. C., Pauciulo, M. W., Lutz, K., Nies, M. K., Rosenzweig, E. B., Hirsch, R., Yung, D. & Everett, A. D., Oct 19 2021, In: Journal of the American Heart Association. 10, 20, e021409.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Angiostatic Proteins 100%
  • Endostatins 69%
  • Pulmonary Hypertension 48%
  • Heart 31%
  • Pediatrics 31%

• Cenobamate treatment of focal-onset seizures: Quality of life and outcome during up to eight years of treatment

  Elizebath, R., Zhang, E., Coe, P., Gutierrez, E. G., Yang, J. & Krauss, G. L., Mar 2021, In: Epilepsy and Behavior. 116, 107796.

  Research output: Contribution to journal › Article › peer-review

  • Seizures 100%
  • Quality of Life 83%
  • Partial Epilepsy 27%
  • Therapeutics 21%
  • Drug Resistant Epilepsy 13%

• Dysregulated miRNAs mark Parkinson’s disease progression

  Rosenthal, L. S., Yang, J. & Mao, X., Mar 2021, In: Nature Aging. 1, 3, p. 241-242 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Proteomic discovery in sickle cell disease: Elevated neurogranin levels in children with sickle cell disease

  Lance, E. I., Faulcon, L. M., Fu, Z., Yang, J., Whyte-Stewart, D., Strouse, J. J., Barron-Casella, E., Jones, K., Van Eyk, J. E., Casella, J. F. & Everett, A. D., Sep 2021, In: Proteomics - Clinical Applications. 15, 5, 2100003.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neurogranin 100%
  • Sickle Cell Anemia 64%
  • Proteomics 53%
  • Plasma 36%
  • Cerebral Infarction 27%

• ST2 Is a Biomarker of Pediatric Pulmonary Arterial Hypertension Severity and Clinical Worsening

  Griffiths, M., Yang, J., Simpson, C. E., Vaidya, D., Nies, M., Brandal, S., Damico, R., Ivy, D. D., Austin, E. D., Pauciulo, M. W., Lutz, K. A., Rosenzweig, E. B., Hirsch, R., Yung, D., Nichols, W. C. & Everett, A. D., Jul 2021, In: CHEST. 160, 1, p. 297-306 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pulmonary Arterial Hypertension 100%
  • Pulmonary Hypertension 67%
  • Pulmonary Artery 62%
  • Biomarkers 55%
  • Pediatrics 54%

• The angiostatic peptide endostatin enhances mortality risk prediction in pulmonary arterial hypertension

  Simpson, C. E., Griffiths, M., Yang, J., Nies, M. K., Vaidya, R. D., Brandal, S., Martin, L. J., Pauciulo, M. W., Lutz, K. A., Coleman, A. W., Austin, E. D., Ivy, D. D., Nichols, W. C., Everett, A. D., Hassoun, P. M. & Damico, R. L., Oct 1 2021, In: ERJ Open Research. 7, 4, 00378-2021.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Angiostatic Proteins 100%
  • Endostatins 69%
  • Pulmonary Arterial Hypertension 57%
  • Mortality 24%
  • Cardiology 8%
• 2020

  Association of Neurodevelopmental Outcomes with Environmental Exposure to Cyclohexanone during Neonatal Congenital Cardiac Operations: A Secondary Analysis of a Randomized Clinical Trial

  Everett, A. D., Buckley, J. P., Ellis, G., Yang, J., Graham, D., Griffiths, M., Bembea, M. & Graham, E. M., May 2020, In: JAMA Network Open. 3, 5, e204070.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • cyclohexanone 100%
  • Environmental Exposure 62%
  • Randomized Controlled Trials 38%
  • Language 18%
  • Newborn Infant 13%
  3 Scopus citations

• Cellular sources of IL-6 and associations with clinical phenotypes and outcomes in PAH

  Simpson, C. E., Chen, J. Y., Damico, R. L., Hassoun, P. M., Martin, L. J., Yang, J., Nies, M., Griffiths, M., Dhananjay Vaidya, R., Brandal, S., Pauciulo, M. W., Lutz, K. A., Coleman, A. W., Austin, E. D., Ivy, D. D., Nichols, W. C. & Everett, A. D., Apr 1 2020, In: European Respiratory Journal. 55, 4

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pulmonary Arterial Hypertension 100%
  • Interleukin-6 65%
  • Phenotype 51%
  • Pulmonary Artery 15%
  • Smooth Muscle Myocytes 14%
  6 Scopus citations

• Correction: Endostatin and ST2 are predictors of pulmonary hypertension disease course in infants (Journal of Perinatology, (2020), 40, 11, (1625-1633), 10.1038/s41372-020-0671-8)

  Griffiths, M., Yang, J., Everett, A. D., Jennings, J. M., Freire, G., Williams, M., Nies, M., McGrath-Morrow, S. A. & Collaco, J. M., Nov 1 2020, In: Journal of Perinatology. 40, 11, p. 1729 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Perinatology 100%
  • Endostatins 91%
  • Pulmonary Hypertension 63%
  • Lung Diseases 57%
  • Pediatrics 41%

• Elevated Interleukin-6 Levels Predict Clinical Worsening in Pediatric Pulmonary Arterial Hypertension

  Chen, J. Y., Griffiths, M., Yang, J., Nies, M. K., Damico, R. L., Simpson, C. E., Vaidya, R. D., Brandal, S., Ivy, D. D., Austin, E. D., Nichols, W. C., Pauciulo, M. W., Lutz, K., Rosenzweig, E. B., Hirsch, R., Yung, D. & Everett, A. D., Aug 2020, In: Journal of Pediatrics. 223, p. 164-169.e1

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pulmonary Arterial Hypertension 100%
  • Interleukin-6 65%
  • Pediatrics 54%
  • National Heart, Lung, and Blood Institute (U.S.) 14%
  • Familial Primary Pulmonary Hypertension 13%

• Endostatin and ST2 are predictors of pulmonary hypertension disease course in infants

  Griffiths, M., Yang, J., Everett, A. D., Jennings, J. M., Freire, G., Williams, M., Nies, M., McGrath-Morrow, S. A. & Collaco, J. M., Nov 1 2020, In: Journal of Perinatology. 40, 11, p. 1625-1633 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Endostatins 100%
  • Pulmonary Hypertension 70%
  • Lung Diseases 63%
  • pro-brain natriuretic peptide (1-76) 34%
  • Right Ventricular Dysfunction 11%

• Insulin-like growth factor binding protein-2: A new circulating indicator of pulmonary arterial hypertension severity and survival

  Yang, J., Griffiths, M., Nies, M. K., Brandal, S., Damico, R., Vaidya, D., Tao, X., Simpson, C. E., Kolb, T. M., Mathai, S. C., Pauciulo, M. W., Nichols, W. C., Ivy, D. D., Austin, E. D., Hassoun, P. M. & Everett, A. D., Oct 6 2020, In: BMC medicine. 18, 1, 268.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Insulin-Like Growth Factor Binding Protein 2 100%
  • Pulmonary Arterial Hypertension 82%
  • Survival 39%
  • Pulmonary Artery 16%
  • Smooth Muscle Myocytes 15%
  1 Scopus citations

• Noninvasive Prognostic Biomarkers for Left-Sided Heart Failure as Predictors of Survival in Pulmonary Arterial Hypertension

  Simpson, C. E., Damico, R. L., Hassoun, P. M., Martin, L. J., Yang, J., Nies, M. K., Vaidya, R. D., Brandal, S., Pauciulo, M. W., Austin, E. D., Ivy, D. D., Nichols, W. C. & Everett, A. D., Jun 2020, In: CHEST. 157, 6, p. 1606-1616 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pulmonary Arterial Hypertension 100%
  • pro-brain natriuretic peptide (1-76) 79%
  • Heart Failure 62%
  • Biomarkers 55%
  • Survival 47%
  5 Scopus citations

• Normative values for circulating intestinal fatty acid binding protein and calprotectin across gestational ages

  Shores, D. R., Fundora, J., Go, M., Shakeel, F., Brooks, S., Alaish, S. M., Yang, J., Sodhi, C. P., Hackam, D. J. & Everett, A., May 26 2020, In: BMC Pediatrics. 20, 1, 250.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Leukocyte L1 Antigen Complex 100%
  • Fatty Acid-Binding Proteins 94%
  • Gestational Age 62%
  • Premature Infants 40%
  • Serum 14%
  2 Scopus citations

• Pediatric pulmonary hypertension: insulin-like growth factor-binding protein 2 is a novel marker associated with disease severity and survival

  Griffiths, M., Yang, J., Nies, M., Vaidya, D., Brandal, S., Williams, M., Matsui, E. C., Grant, T., Damico, R., Ivy, D., Austin, E. D., Nichols, W. C., Pauciulo, M. W., Lutz, K., Rosenzweig, E. B., Hirsch, R., Yung, D. & Everett, A. D., Dec 2020, In: Pediatric research. 88, 6, p. 850-856 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Insulin-Like Growth Factor Binding Protein 2 100%
  • Pulmonary Hypertension 70%
  • Pediatrics 45%
  • Somatomedins 37%
  • Pulmonary Arterial Hypertension 20%
• 2016

  Hepatoma-derived growth factor predicts disease severity and survival in pulmonary arterial hypertension

  Yang, J., Nies, M. K., Fu, Z., Damico, R., Korley, F. K., Hassoun, P. M., Ivy, D. D., Austin, E. D. & Everett, A. D., Nov 15 2016, In: American journal of respiratory and critical care medicine. 194, 10, p. 1264-1272 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • hepatoma-derived growth factor 100%
  • Pulmonary Arterial Hypertension 65%
  • Survival 30%
  • Brain Natriuretic Peptide 11%
  • Mortality 7%
  7 Scopus citations
• 2015

  Serum neurogranin measurement as a biomarker of acute traumatic brain injury

  Yang, J., Korley, F. K., Dai, M. & Everett, A. D., Sep 1 2015, In: Clinical Biochemistry. 48, 13-14, p. 843-848 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neurogranin 100%
  • Traumatic Brain Injury 57%
  • Brain Injuries 56%
  • Biological Marker 52%
  • Intracranial 46%
  15 Scopus citations
• 2013

  Identification and characterization of citrulline-modified brain proteins by combining HCD and CID fragmentation

  Jin, Z., Fu, Z., Yang, J., Troncosco, J., Everett, A. D. & Van Eyk, J. E., Sep 2013, In: Proteomics. 13, 17, p. 2682-2691 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • CID 87%
  • Citrulline 81%
  • Fragmentation 51%
  • Dissociation 44%
  • Brain 30%
  34 Scopus citations

• The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression

  Jelicic, K., Cimbro, R., Nawaz, F., Huang, D. W., Zheng, X., Yang, J., Lempicki, R. A., Pascuccio, M., Van Ryk, D., Schwing, C., Hiatt, J., Okwara, N., Wei, D., Roby, G., David, A., Hwang, I. Y., Kehrl, J. H., Arthos, J., Cicala, C. & Fauci, A. S., Dec 2013, In: Nature Immunology. 14, 12, p. 1256-1265 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Human immunodeficiency virus 1 gp120 protein 100%
  • B-Lymphocytes 42%
  • Cell Proliferation 36%
  • HIV-1 32%
  • Humoral Immunity 19%
  68 Scopus citations
• 2011

  Mitotic phosphorylation activates hepatoma-derived growth factor as a mitogen

  Everett, A. D., Yang, J., Rahman, M., Dulloor, P. & Brautigan, D. L., Apr 13 2011, In: BMC Cell Biology. 12, 15.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • hepatoma-derived growth factor 100%
  • Mitogens 56%
  • Phosphorylation 38%
  • Phosphoproteins 11%
  • Mitosis 9%
  11 Scopus citations
• 2010

  Development and clinical evaluation of a multi-purpose mAb and a sandwich ELISA test for hepatoma-derived growth factor in lung cancer patients

  Zhang, A., Long, W., Guo, Z., Liu, G., Hu, Z., Huang, Y., Li, Y., Grabinski, T. M., Yang, J., Zhao, P. X., Everett, A. D., Zhang, Y. & Cao, B. B., Apr 2010, In: Journal of Immunological Methods. 355, 1-2, p. 61-67 7 p.

  Research output: Contribution to journal › Article › peer-review

  • hepatoma-derived growth factor 100%
  • Lung Neoplasms 44%
  • Enzyme-Linked Immunosorbent Assay 39%
  • Serum 12%
  • Immunohistochemistry 9%
  9 Scopus citations
• 2009

  Hepatoma-derived Growth Factor Represses SET and MYND Domain Containing 1 Gene Expression through Interaction with C-terminal Binding Protein

  Yang, J. & Everett, A. D., Mar 6 2009, In: Journal of molecular biology. 386, 4, p. 938-950 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • MYND Domains 100%
  • hepatoma-derived growth factor 97%
  • C-terminal binding protein 91%
  • PR-SET Domains 83%
  • Gene Expression 32%
  30 Scopus citations
• 2008

  The isolation of novel mesenchymal stromal cell chemotactic factors from the conditioned medium of tumor cells

  Lin, S. Y., Yang, J., Everett, A. D., Clevenger, C. V., Koneru, M., Mishra, P. J., Kamen, B., Banerjee, D. & Glod, J., Oct 15 2008, In: Experimental cell research. 314, 17, p. 3107-3117 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chemotactic Factors 100%
  • Conditioned Culture Medium 90%
  • Mesenchymal Stem Cells 79%
  • Chemotaxis 40%
  • Neoplasms 28%
  42 Scopus citations
• 2007

  Hepatoma derived growth factor binds DNA through the N-terminal PWWP domain

  Yang, J. & Everett, A. D., Oct 31 2007, In: BMC Molecular Biology. 8, 101.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • hepatoma-derived growth factor 100%
  • DNA 31%
  • DNA-Binding Proteins 11%
  • Conserved Sequence 8%
  • Chromatin Immunoprecipitation 7%
  50 Scopus citations