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Research Output 1996 2019

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2019

Activation of BMP Signaling by FKBP12 Ligands Synergizes with Inhibition of CXCR4 to Accelerate Wound Healing

Peiffer, B. J., Qi, L., Ahmadi, A. R., Wang, Y., Guo, Z., Peng, H., Sun, Z. L. & Liu, J., May 16 2019, In : Cell Chemical Biology. 26, 5, p. 652-661.e4

Research output: Contribution to journalArticle

Tacrolimus Binding Protein 1A
Tacrolimus
Wound Healing
Chemical activation
Ligands

Discovery of a Potent GLUT Inhibitor from a Library of Rapafucins by Using 3D Microarrays

Guo, Z., Cheng, Z., Wang, J., Liu, W., Peng, H., Wang, Y., Rao, A. V. S., Li, R. J., Ying, X., Korangath, P., Liberti, M. V., Li, Y., Xie, Y., Hong, S. Y., Schiene-Fischer, C., Fischer, G., Locasale, J. W., Sukumar, S., Zhu, H. & Liu, J. O., Nov 25 2019, In : Angewandte Chemie - International Edition. 58, 48, p. 17158-17162 5 p.

Research output: Contribution to journalArticle

Microarrays
Glucose
Cells
Enzyme inhibition
Facilitative Glucose Transport Proteins

One-step Heck Reaction Generates Nonimmunosuppressive FK506 Analogs for Pharmacological BMP Activation

Wang, Y., Peiffer, B. J., Su, Q. & Liu, J., Sep 12 2019, In : ACS Medicinal Chemistry Letters. 10, 9, p. 1279-1283 5 p.

Research output: Contribution to journalArticle

Tacrolimus
Chemical activation
Pharmacology
Calcineurin
Tacrolimus Binding Protein 1A

Pharmacologic activation of Lytic Epstein-Barr Virus gene expression without virion production

Lee, J., Kosowicz, J. G., Hayward, S. D., Desai, P., Stone, J., Lee, J. M., Liu, J. & Ambinder, R. F., Oct 1 2019, In : Journal of virology. 93, 20, e00998-19.

Research output: Contribution to journalArticle

Human herpesvirus 4
Human Herpesvirus 4
virion
Virion
viral proteins

Pharmacophore-Directed Retrosynthesis Applied to Rameswaralide: Synthesis and Bioactivity of Sinularia Natural Product Tricyclic Cores

Truax, N. J., Ayinde, S., Van, K., Liu, J. & Romo, D., Sep 20 2019, In : Organic Letters. 21, 18, p. 7394-7399 6 p.

Research output: Contribution to journalArticle

Bioactivity
Biological Products
Bearings (structural)
Anthozoa
Structure-Activity Relationship
2018

Astemizole inhibits mTOR signaling and angiogenesis by blocking cholesterol trafficking

Lyu, J., Yang, E. J., Head, S. A., Ai, N., Zhang, B., Wu, C., Li, R. J., Liu, Y., Chakravarty, H., Zhang, S., Tam, K. Y., Dang, Y., Kwon, H. J., Ge, W., Liu, J. & Shim, J. S., Jun 23 2018, In : International Journal of Biological Sciences. 14, 10, p. 1175-1185 11 p.

Research output: Contribution to journalArticle

Astemizole
trafficking
Sirolimus
angiogenesis
Cholesterol

Novel Tetrazole-Containing Analogues of Itraconazole as Potent Antiangiogenic Agents with Reduced Cytochrome P450 3A4 Inhibition

Li, Y., Pasunooti, K. K., Li, R. J., Liu, W., Head, S. A., Shi, W. Q. & Liu, J., Dec 27 2018, In : Journal of Medicinal Chemistry. 61, 24, p. 11158-11168 11 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Angiogenesis Inhibitors
Itraconazole
Azoles
AMP-Activated Protein Kinases

Prolyl 4-hydroxylase 2 promotes B-cell lymphoma progression via hydroxylation of Carabin

Jiang, W., Zhou, X., Li, Z., Liu, K., Wang, W., Tan, R., Cong, X., Shan, J., Zhan, Y., Cui, Z., Jiang, L., Li, Q., Shen, S., Bai, M., Cheng, Y., Li, B., Tan, M., Ma, D. K., Liu, J. & Dang, Y., Mar 22 2018, In : Blood. 131, 12, p. 1325-1336 12 p.

Research output: Contribution to journalArticle

Prolyl Hydroxylases
Hydroxylation
B-Cell Lymphoma
Cells
Lymphoma, Large B-Cell, Diffuse

Rapamycin-inspired macrocycles with new target specificity

Guo, Z., Hong, S. Y., Wang, J., Rehan, S., Liu, W., Peng, H., Das, M., Li, W., Bhat, S., Peiffer, B., Ullman, B. R., Tse, C. M., Tarmakova, Z., Schiene-Fischer, C., Fischer, G., Coe, I., Paavilainen, V. O., Sun, Z. L. & Liu, J., Jan 1 2018, (Accepted/In press) In : Nature Chemistry.

Research output: Contribution to journalArticle

Tacrolimus Binding Proteins
Sirolimus
Calcineurin
Proteins
Equilibrative Nucleoside Transporter 1

Repurposing tofacitinib as an anti-myeloma therapeutic to reverse growth-promoting effects of the bone marrow microenvironment

Lam, C., Ferguson, I. D., Mariano, M. C., Lin, Y. H. T., Murnane, M., Liu, H., Smith, G. A., Wong, S. W., Taunton, J., Liu, J., Mitsiades, C. S., Hann, B. C., Aftab, B. T. & Wiita, A. P., Jul 3 2018, In : Haematologica. 103, 7, p. 1218-1228 11 p.

Research output: Contribution to journalArticle

Bone Marrow
Mesenchymal Stromal Cells
United States Food and Drug Administration
Growth
Therapeutics

Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP)

Bauer, L., Ferla, S., Head, S. A., Bhat, S., Pasunooti, K. K., Shi, W. Q., Albulescu, L., Liu, J., Brancale, A., van Kuppeveld, F. J. M. & Strating, J. R. P. M., Aug 1 2018, In : Antiviral Research. 156, p. 55-63 9 p.

Research output: Contribution to journalArticle

Picornaviridae
Itraconazole
Structure-Activity Relationship
Antiviral Agents
Cardiovirus

USP9X controls translation efficiency via deubiquitination of eukaryotic translation initiation factor 4A1

Li, Z., Cheng, Z., Raghothama, C., Cui, Z., Liu, K., Li, X., Jiang, C., Jiang, W., Tan, M., Ni, X., Pandey, A., Liu, J. & Dang, Y., Jan 25 2018, In : Nucleic Acids Research. 46, 2, p. 823-839 17 p.

Research output: Contribution to journalArticle

Eukaryotic Initiation Factor-4A
Eukaryotic Initiation Factors
Ubiquitin
Peptide Hydrolases
Messenger RNA
2017

Drug modulators of B cell signaling pathways and Epstein-Barr virus lytic activation

Kosowicz, J. G., Lee, J., Peiffer, B., Guo, Z., Chen, J., Liao, G., Diane Hayward, S., Liu, J. & Ambinder, R. F., Aug 1 2017, In : Journal of Virology. 91, 16, e00747-17.

Research output: Contribution to journalArticle

Virus Activation
Human herpesvirus 4
Human Herpesvirus 4
B-lymphocytes
B-Lymphocytes

Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth

Lyu, J., Yang, E. J., Head, S. A., Ai, N., Zhang, B., Wu, C., Li, R. J., Liu, Y., Yang, C., Dang, Y., Kwon, H. J., Ge, W., Liu, J. & Shim, J. S., Nov 28 2017, In : Cancer Letters. 409, p. 91-103 13 p.

Research output: Contribution to journalArticle

Endothelial Cells
Cholesterol
Pharmacology
Growth
Neoplasms

Simultaneous targeting of NPC1 and VDAC1 by itraconazole leads to synergistic inhibition of MTOR signaling and angiogenesis

Head, S. A., Shi, W. Q., Yang, E. J., Nacev, B. A., Hong, S. Y., Pasunooti, K. K., Li, R. J., Shim, J. S. & Liu, J., Jan 1 2017, In : ACS Chemical Biology. 12, 1, p. 174-182 9 p.

Research output: Contribution to journalArticle

Itraconazole
AMP-Activated Protein Kinases
Cholesterol
Chemical activation
Mutagenesis
2016

Antidepressant indatraline induces autophagy and inhibits restenosis via suppression of mTOR/S6 kinase signaling pathway

Cho, Y. S., Yen, C. N., Shim, J. S., Kang, D. H., Kang, S. W., Liu, J. & Kwon, H. J., Oct 3 2016, In : Scientific Reports. 6, 34655.

Research output: Contribution to journalArticle

Ribosomal Protein S6 Kinases
Autophagy
Antidepressive Agents
Neurotransmitter Uptake Inhibitors
Smooth Muscle Myocytes

Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs

Fox, J. M., Moynihan, J. R., Mott, B. T., Mazzone, J. R., Anders, N., Brown, P. A., Rudek-Renaut, M., Liu, J., Boger, R., Posner, G. H., Civin, C. I. & Chen, X., 2016, In : Oncotarget. 7, 6, p. 7268-7279 12 p.

Research output: Contribution to journalArticle

Leukemia
Pharmaceutical Preparations
SCID Mice
Antimalarials
Artemisinins

Characterization of 2-hydroxy-1-naphthaldehyde isonicotinoyl hydrazone as a novel inhibitor of methionine aminopeptidases from Mycobacterium tuberculosis

John, S. F., Aniemeke, E., Ha, N. P., Chong, C. R., Gu, P., Zhou, J., Zhang, Y., Graviss, E. A., Liu, J. & Olaleye, O. A., Dec 1 2016, In : Tuberculosis. 101, p. S73-S77

Research output: Contribution to journalArticle

Hydrazones
Aminopeptidases
Mycobacterium tuberculosis
Methionine
HIV

Derivatization of agelastatin A leading to bioactive analogs and a trifunctional probe

Jouanneau, M., McClary, B., Reyes, J. C. P., Chen, R., Chen, Y., Plunkett, W., Cheng, X., Milinichik, A. Z., Albone, E. F., Liu, J. & Romo, D., Apr 15 2016, In : Bioorganic and Medicinal Chemistry Letters. 26, 8, p. 2092-2097 6 p.

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
T-cells
Diazomethane
Derivatives
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Divergence of antiangiogenic activity and hepatotoxicity of different stereoisomers of itraconazole

Shim, J. S., Li, R. J., Bumpus, N. N., Head, S. A., Pasunooti, K. K., Yang, E. J., Lv, J., Shi, W. & Liu, J., Jun 1 2016, In : Clinical Cancer Research. 22, 11, p. 2709-2720 12 p.

Research output: Contribution to journalArticle

Stereoisomerism
Itraconazole
Pharmaceutical Preparations
Triazoles
Human Umbilical Vein Endothelial Cells
Labeling
Carrier Proteins
Molecules
Drug Discovery
Cell Communication

Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A

McClary, B., Zinshteyn, B., Meyer, M., Jouanneau, M., Pellegrino, S., Yusupova, G., Schuller, A., Reyes, J. C. P., Lu, J., Guo, Z., Ayinde, S., Luo, C., Dang, Y., Romo, D., Yusupov, M., Green, R. & Liu, J., Dec 18 2016, (Accepted/In press) In : Cell Chemical Biology.

Research output: Contribution to journalArticle

Biological Products
Ribosomes
agelastatin A
Chemotherapy
Cell proliferation

Insights into the structure-activity relationship of the anticancer compound ZJ-101: A critical role played by the cyclohexene ring

Shah, A. K., Qian, S., Zhang, D., Head, S. A., Liu, J. & Jin, Z., Mar 30 2016, (Accepted/In press) In : Bioorganic and Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

Structure-Activity Relationship
Biological Products
Cells
Neoplasms
superstolide A
Lactones
Biological Products
Derivatives
Lactams
Molecules
Lactones
Biological Products
Derivatives
Molecules
Cells

Regulation of mTORC1 by lysosomal calcium and calmodulin

Li, R. J., Xu, J., Fu, C., Zhang, J., Zheng, Y. G., Jia, H. & Liu, J., Oct 27 2016, In : eLife. 5

Research output: Contribution to journalArticle

Calmodulin
Calcium
Phosphotransferases
Chemical activation
Calcium-Calmodulin-Dependent Protein Kinases

Regulation of mTORC1 by lysosomal calcium and calmodulin

Li, R. J., Xu, J., Fu, C., Zhang, J., Zheng, Y. G., Jia, H., Liu, J. & Czech, M., Oct 27 2016, In : eLife. 5, OCTOBER2016, e19360.

Research output: Contribution to journalArticle

Calmodulin
Calcium
Phosphotransferases
Chemical activation
mechanistic target of rapamycin complex 1

Sphingosine 1-Phosphate Activation of EGFR As a Novel Target for Meningitic Escherichia coli Penetration of the Blood-Brain Barrier

Wang, X., Maruvada, R., Morris, A. J., Liu, J., Wolfgang, M. J., Baek, D. J., Bittman, R. & Kim, K. S., Oct 1 2016, In : PLoS Pathogens. 12, 10, e1005926.

Research output: Contribution to journalArticle

Blood-Brain Barrier
Epidermal Growth Factor Receptor
Escherichia coli
Lysosphingolipid Receptors
Escherichia coli Meningitis

Targeted Delivery and Sustained Antitumor Activity of Triptolide through Glucose Conjugation

He, Q. L., Minn, I., Wang, Q., Xu, P., Head, S. A., Datan, E., Yu, B., Pomper, M. G. & Liu, J., 2016, (Accepted/In press) In : Angewandte Chemie - International Edition.

Research output: Contribution to journalArticle

Glucose
Tumors
Cells
Solubility
Transcription factors
2015

A gating mechanism for Pi release governs the mRNA unwinding by eIF4AI during translation initiation

Lu, J., Jiang, C., Li, X., Jiang, L., Li, Z., Schneider-Poetsch, T., Liu, J., Yu, K., Liu, J., Jiang, H., Luo, C. & Dang, Y., 2015, In : Nucleic Acids Research. 43, 21, p. 10157-10167 11 p.

Research output: Contribution to journalArticle

Hydrolysis
Messenger RNA
Adenosine Triphosphate
Substrate Cycling
Eukaryotic Initiation Factors

Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells

Head, S. A., Shi, W., Zhao, L., Gorshkov, K., Pasunooti, K., Chen, Y., Deng, Z., Li, R. J., Shim, J. S., Tan, W., Hartung, T., Zhang, J., Zhao, Y., Colombini, M. & Liu, J., Dec 29 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 52, p. E7276-E7285

Research output: Contribution to journalArticle

Voltage-Dependent Anion Channel 1
AMP-Activated Protein Kinases
Itraconazole
Sirolimus
Endothelial Cells

Covalent modification of a cysteine residue in the XPB subunit of the general transcription factor TFIIH through single epoxide cleavage of the transcription inhibitor triptolide

He, Q. L., Titov, D. V., Li, J., Tan, M., Ye, Z., Zhao, Y., Romo, D. & Liu, J., Feb 9 2015, In : Angewandte Chemie - International Edition. 54, 6, p. 1859-1863 5 p.

Research output: Contribution to journalArticle

Transcription Factor TFIIH
General Transcription Factors
Transcription factors
Epoxy Compounds
Transcription

Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors

He, R., Yu, Z. H., Zhang, R. Y., Wu, L., Gunawan, A. M., Lane, B. S., Shim, J. S., Zeng, L. F., He, Y., Chen, L., Wells, C. D., Liu, J. & Zhang, Z. Y., Jul 9 2015, In : ACS Medicinal Chemistry Letters. 6, 7, p. 782-786 5 p.

Research output: Contribution to journalArticle

Phosphotyrosine
Protein Tyrosine Phosphatases
Cefsulodin
Amides
Acetic Acid

First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass

Wang, G., Rajpurohit, S. K., Delaspre, F., Walker, S. L., White, D. T., Ceasrine, A., Kuruvilla, R., Li, R. J., Shim, J. S., Liu, J., Parsons, M. J. & Mumm, J., Jul 28 2015, In : eLife. 4, JULY2015

Research output: Contribution to journalArticle

Zebrafish
Screening
Throughput
Drug Discovery
Cell Proliferation

Genetic Variants in Five Novel Loci Including CFB and CD40 Predispose to Chronic Hepatitis B

Jiang, D. K., Ma, X. P., Yu, H., Cao, G., Ding, D. L., Chen, H., Huang, H. X., Gao, Y. Z., Wu, X. P., Long, X. D., Zhang, H., Zhang, Y., Gao, Y., Chen, T. Y., Ren, W. H., Zhang, P., Shi, Z., Jiang, W., Wan, B., Saiyin, H. & 21 others, Yin, J., Zhou, Y. F., Zhai, Y., Lu, P. X., Zhang, H., Gu, X., Tan, A., Wang, J. B., Zuo, X. B., Sun, L. D., Liu, J., Yi, Q., Mo, Z., Zhou, G., Liu, Y., Sun, J., Shugart, Y. Y., Zheng, S. L., Zhang, X. J., Xu, J. & Yu, L., Jul 1 2015, In : Hepatology. 62, 1, p. 118-128 11 p.

Research output: Contribution to journalArticle

Complement Factor B
Chronic Hepatitis B
HLA Antigens
China
Genome-Wide Association Study

Identification of novel vascular projections with cellular trafficking abilities on the microvasculature of pancreatic ductal adenocarcinoma

Saiyin, H., Ardito-Abraham, C. M., Wu, Y., Wei, Y., Fang, Y., Han, X., Li, J., Zhou, P., Yi, Q., Maitra, A., Liu, J., Tuveson, D. A., Lou, W. & Yu, L., Jun 1 2015, In : Journal of Pathology. 236, 2, p. 142-154 13 p.

Research output: Contribution to journalArticle

Microvessels
Blood Vessels
Adenocarcinoma
Microvilli
Neoplasms

Inhibition of angiogenesis by selective estrogen receptor modulators through blockade of cholesterol trafficking rather than estrogen receptor antagonism

Shim, J. S., Li, R. J., Lv, J., Head, S. A., Yang, E. J. & Liu, J., 2015, In : Cancer Letters. 362, 1, p. 106-115 10 p.

Research output: Contribution to journalArticle

Selective Estrogen Receptor Modulators
Tamoxifen
Estrogen Receptors
Cholesterol
Vascular Endothelial Growth Factor Receptor-2

Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein

Strating, J. R. P. M., van der Linden, L., Albulescu, L., Bigay, J., Arita, M., Delang, L., Leyssen, P., van der Schaar, H. M., Lanke, K. H. W., Thibaut, H. J., Ulferts, R., Drin, G., Schlinck, N., Wubbolts, R. W., Sever, N., Head, S. A., Liu, J., Beachy, P. A., DeMatteis, M. A., Shair, M. D. & 3 others, Olkkonen, V. M., Neyts, J. & van Kuppeveld, F. J. M., Feb 3 2015, In : Cell Reports. 10, 4, p. 600-615 16 p.

Research output: Contribution to journalArticle

Itraconazole
Enterovirus
Viruses
Virus Replication
Antiviral Agents

Regulation of cell cycle of hepatocellular carcinoma by NF90 through modulation of cyclin E1 mRNA stability

Jiang, W., Huang, H., Ding, L., Zhu, P., Saiyin, H., Ji, G., Zuo, J., Han, D., Pan, Y., Ding, D., Ma, X., Zhang, Y., Wu, J., Yi, Q., Liu, J., Huang, H., Dang, Y. & Yu, L., Aug 20 2015, In : Oncogene. 34, 34, p. 4460-4470 11 p.

Research output: Contribution to journalArticle

Nuclear Factor 90 Proteins
Cyclins
RNA Stability
Hepatocellular Carcinoma
Cell Cycle

Targeted therapy for Epstein-Barr virus-associated gastric carcinoma using low-dose gemcitabine-induced lytic activation

Lee, H. G., Kim, H., Kim, E. J., Park, P. G., Dong, S. M., Choi, T. H., Kim, H., Chong, C. R., Liu, J., Chen, J., Ambinder, R. F., Hayward, S. D., Park, J. H. & Lee, J. M., 2015, In : Oncotarget. 6, 31, p. 31018-31029 12 p.

Research output: Contribution to journalArticle

gemcitabine
Human Herpesvirus 4
Stomach
Carcinoma
Ganciclovir
2014

Identification of an old antibiotic clofoctol as a novel activator of unfolded protein response pathways and an inhibitor of prostate cancer

Wang, M., Shim, J. S., Li, R. J., Dang, Y., He, Q., Das, M. & Liu, J., Oct 1 2014, In : British Journal of Pharmacology. 171, 19, p. 4478-4489 12 p.

Research output: Contribution to journalArticle

Unfolded Protein Response
Prostatic Neoplasms
Anti-Bacterial Agents
Drug Repositioning
Pharmaceutical Preparations
Hematopoietic Stem Cell Mobilization
Tacrolimus
Stem cells
Regeneration
Skin

Recent advances in drug repositioning for the discovery of new anticancer drugs

Shim, J. S. & Liu, J., Jun 10 2014, In : International Journal of Biological Sciences. 10, 7, p. 654-663 10 p.

Research output: Contribution to journalArticle

Drug Repositioning
new drugs
antineoplastic agents
Drug Discovery
drug

Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents

Low, W. K., Li, J., Zhu, M., Kommaraju, S. S., Shah-Mittal, J., Hull, K., Liu, J. & Romo, D., Jan 1 2014, In : Bioorganic and Medicinal Chemistry. 22, 1, p. 116-125 10 p.

Research output: Contribution to journalArticle

Structure-Activity Relationship
Antineoplastic Agents
Derivatives
Macrolides
Amines

Small-molecule screening of PC3 prostate cancer cells identifies tilorone dihydrochloride to selectively inhibit cell growth based on cyclin-dependent kinase 5 expression

Wissing, M. D., Dadon, T., Kim, E., Piontek, K. B., Shim, J. S., Kaelber, N. S., Liu, J., Kachhap, S. & Nelkin, B. D., 2014, In : Oncology Reports. 32, 1, p. 419-424 6 p.

Research output: Contribution to journalArticle

Tilorone
Cyclin-Dependent Kinase 5
Prostatic Neoplasms
Growth
Ethacridine
2013

Arginine68 is an essential residue for the C-terminal cleavage of human Atg8 family proteins

Liu, C., Ma, H., Wu, J., Huang, Q., Liu, J. & Yu, L., May 30 2013, In : BMC Cell Biology. 14, 1, 27.

Research output: Contribution to journalArticle

Autophagy
Alternative Splicing
Proteins
Salts
Ubiquitin

Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells

Choi, S. M., Kim, Y., Shim, J. S., Park, J. T., Wang, R. H., Leach, S. D., Liu, J., Deng, C., Ye, Z. & Jang, Y. Y., Jun 2013, In : Hepatology. 57, 6, p. 2458-2468 11 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Preclinical Drug Evaluations
Liver Diseases
Stem Cells
Genes

Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma

Jiang, D. K., Sun, J., Cao, G., Liu, Y., Lin, D., Gao, Y. Z., Ren, W. H., Long, X. D., Zhang, H., Ma, X. P., Wang, Z., Jiang, W., Chen, T. Y., Gao, Y., Sun, L. D., Long, J. R., Huang, H. X., Wang, D., Yu, H., Zhang, P. & 44 others, Tang, L. S., Peng, B., Cai, H., Liu, T. T., Zhou, P., Liu, F., Lin, X., Tao, S., Wan, B., Sai-Yin, H. X. G., Qin, L. X., Yin, J., Liu, L., Wu, C., Pei, Y., Zhou, Y. F., Zhai, Y., Lu, P. X., Tan, A., Zuo, X. B., Fan, J., Chang, J., Gu, X., Wang, N. J., Li, Y., Liu, Y. K., Zhai, K., Zhang, H., Hu, Z., Liu, J., Yi, Q., Xiang, Y., Shi, R., Ding, Q., Zheng, W., Shu, X. O., Mo, Z., Shugart, Y. Y., Zhang, X. J., Zhou, G., Shen, H., Zheng, S. L., Xu, J. & Yu, L., Jan 2013, In : Nature Genetics. 45, 1, p. 72-75 4 p.

Research output: Contribution to journalArticle

HLA-DQ Antigens
Hepatitis B virus
Hepatocellular Carcinoma
Genes
Chronic Hepatitis B

HDGF-related protein-3 is required for anchorage-independent survival and chemoresistance in hepatocellular carcinomas

Xiao, Q., Qu, K., Wang, C., Kong, Y., Liu, C., Jiang, D., Saiyin, H., Jia, F., Ni, C., Chen, T., Zhang, Y., Zhang, P., Qin, W., Sun, Q., Wang, H., Yi, Q., Liu, J., Huang, H. & Yu, L., Mar 2013, In : Gut. 62, 3, p. 440-451 12 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Proteins
Anoikis
Extracellular Signal-Regulated MAP Kinases
hepatoma-derived growth factor

Identification, Biochemical and Structural Evaluation of Species-Specific Inhibitors against Type i Methionine Aminopeptidases

Kishor, C., Arya, T., Reddi, R., Chen, X., Saddanapu, V., Marapaka, A. K., Gumpena, R., Ma, D., Liu, J. & Addlagatta, A., Jul 11 2013, In : Journal of Medicinal Chemistry. 56, 13, p. 5295-5305 11 p.

Research output: Contribution to journalArticle

Aminopeptidases
Methionine
Enzymes
Eukaryota
Enterococcus faecalis