Juan C Troncoso

Professor

1981 …2018
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  • 3 Similar Profiles
Alzheimer Disease Medicine & Life Sciences
Brain Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Parkinson Disease Medicine & Life Sciences
alpha-Synuclein Medicine & Life Sciences
Pathology Medicine & Life Sciences
Amyloid Plaques Medicine & Life Sciences
Neurofibrillary Tangles Medicine & Life Sciences

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Research Output 1981 2018

Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study

Varma, V. R., Oommen, A. M., Varma, S., Casanova, R., An, Y., Andrews, R. M., O’Brien, R., Pletnikova, O., Troncoso, J. C., Toledo, J., Baillie, R., Arnold, M., Kastenmueller, G., Nho, K., Doraiswamy, P. M., Saykin, A. J., Kaddurah-Daouk, R., Legido-Quigley, C. & Thambisetty, M., Jan 1 2018, In : PLoS Medicine. 15, 1, e1002482

Research output: Contribution to journalArticle

Metabolomics
Alzheimer Disease
Pathology
Brain
Sphingomyelins

Discovery of noncanonical translation initiation sites through mass spectrometric analysis of protein N termini

Na, C. H., Barbhuiya, M. A., Kim, M. S., Verbruggen, S., Eacker, S. M., Pletnikova, O., Troncoso, J. C., Halushka, M. K., Menschaert, G., Overall, C. M. & Pandey, A., Jan 1 2018, In : Genome Research. 28, 1, p. 25-36 12 p.

Research output: Contribution to journalArticle

Ribosomes
Methionine
Translational Peptide Chain Initiation
Proteins
Initiator Codon

Discrete Pools of Oligomeric Amyloid-β Track with Spatial Learning Deficits in a Mouse Model of Alzheimer Amyloidosis

Chiang, A. C. A., Fowler, S. W., Reddy, R., Pletnikova, O., Troncoso, J. C., Sherman, M. A., Lesne, S. E. & Jankowsky, J. L., Mar 1 2018, In : American Journal of Pathology. 188, 3, p. 739-756 18 p.

Research output: Contribution to journalArticle

Amyloidosis
Amyloid
Detergents
Spatial Learning
Trans-Activators

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

ITALSGEN Consortium, Genomic Translation for ALS Care (GTAC) Consortium, ALS Sequencing Consortium, NYGC ALS Consortium, Answer ALS Foundation, Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe) Consortium, SLAGEN Consortium, French ALS Consortium & Project MinE ALS Sequencing Consortium, Mar 21 2018, In : Neuron. 97, 6, p. 1268-1283.e6

Research output: Contribution to journalArticle

Kinesin
Genome
Mutation
Genes
Genome-Wide Association Study

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

Guerreiro, R. , Ross, O. A. , Kun-Rodrigues, C. , Hernandez, D. G. , Orme, T. , Eicher, J. D. , Shepherd, C. E. , Parkkinen, L. , Darwent, L. , Heckman, M. G. , Scholz, S. W. , Troncoso, J. C. , Pletnikova, O. , Ansorge, O. , Clarimon, J. , Lleo, A. , Morenas-Rodriguez, E. , Clark, L. , Honig, L. S. , Marder, K. & 45 others Lemstra, A., Rogaeva, E., St George-Hyslop, P., Londos, E., Zetterberg, H., Barber, I., Braae, A., Brown, K., Morgan, K., Troakes, C., Al-Sarraj, S., Lashley, T., Holton, J., Compta, Y., Van Deerlin, V., Serrano, G. E., Beach, T. G., Lesage, S., Galasko, D., Masliah, E., Santana, I., Pastor, P., Diez-Fairen, M., Aguilar, M., Tienari, P. J., Myllykangas, L., Oinas, M., Revesz, T., Lees, A., Boeve, B. F., Petersen, R. C., Ferman, T. J., Escott-Price, V., Graff-Radford, N., Cairns, N. J., Morris, J. C., Pickering-Brown, S., Mann, D., Halliday, G. M., Hardy, J., Trojanowski, J. Q., Dickson, D. W., Singleton, A., Stone, D. J. & Bras, J., Jan 1 2018, In : The Lancet Neurology. 17, 1, p. 64-74 11 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Genome-Wide Association Study
Cohort Studies
Odds Ratio
Dementia