Juan C Troncoso

Professor

1981 …2018
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Alzheimer Disease Medicine & Life Sciences
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Research Output 1981 2018

Abnormal CSF amyloid-β42 and tau levels in hip fracture patients without dementia

Oh, E., Blennow, K., Bigelow, G., Inouye, S. K., Marcantonio, E. R., Neufeld, K. J., Rosenberg, P. B., Troncoso, J. C., Wang, N. Y., Zetterberg, H., Sieber, F. & Lyketsos, C. G., Sep 1 2018, In : PloS one. 13, 9, e0204695.

Research output: Contribution to journalArticle

hip fractures
Cerebrospinal fluid
dementia
Hip Fractures
cerebrospinal fluid

Amyloid β toxic conformer has dynamic localization in the human inferior parietal cortex in absence of amyloid plaques

Kageyama, Y., Saito, A., Pletnikova, O., Rudow, G. L., Irie, Y., An, Y., Murakami, K., Irie, K., Resnick, S. M., Fowler, D. R., Martin, L. J. & Troncoso, J. C., Dec 1 2018, In : Scientific Reports. 8, 1, 16895.

Research output: Contribution to journalArticle

Parietal Lobe
Poisons
Amyloid Plaques
Amyloid
Extracellular Space

Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study

Varma, V. R., Oommen, A. M., Varma, S., Casanova, R., An, Y., Andrews, R. M., O’Brien, R., Pletnikova, O., Troncoso, J. C., Toledo, J., Baillie, R., Arnold, M., Kastenmueller, G., Nho, K., Doraiswamy, P. M., Saykin, A. J., Kaddurah-Daouk, R., Legido-Quigley, C. & Thambisetty, M., Jan 1 2018, In : PLoS Medicine. 15, 1, e1002482.

Research output: Contribution to journalArticle

Metabolomics
Alzheimer Disease
Pathology
Brain
Sphingomyelins

Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease

Johnson, E. C. B., Dammer, E. B., Duong, D. M., Yin, L., Thambisetty, M., Troncoso, J. C., Lah, J. J., Levey, A. I. & Seyfried, N. T., Oct 4 2018, In : Molecular neurodegeneration. 13, 1, 52.

Research output: Contribution to journalArticle

Protein Splicing
RNA Splicing
RNA-Binding Proteins
Proteomics
Alzheimer Disease

Discovery of noncanonical translation initiation sites through mass spectrometric analysis of protein N termini

Na, C-H., Barbhuiya, M. A., Kim, M. S., Verbruggen, S., Eacker, S., Pletnikova, O., Troncoso, J. C., Halushka, M. K., Menschaert, G., Overall, C. M. & Pandey, A., Jan 1 2018, In : Genome Research. 28, 1, p. 25-36 12 p.

Research output: Contribution to journalArticle

Translational Peptide Chain Initiation
HEK293 Cells
5' Untranslated Regions
Human Umbilical Vein Endothelial Cells
Ribosomes