Joshua Modell

Assistant Professor

20062018
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Fingerprint Dive into the research topics where Joshua Modell is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Clustered Regularly Interspaced Short Palindromic Repeats Medicine & Life Sciences
Caulobacter crescentus Medicine & Life Sciences
Sea Urchins Medicine & Life Sciences
Nonmammalian Embryo Medicine & Life Sciences
Cell Division Medicine & Life Sciences
CRISPR-Cas Systems Medicine & Life Sciences
DNA Damage Medicine & Life Sciences
Nodal Protein Medicine & Life Sciences

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Research Output 2006 2018

Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts

Goldberg, G. W., McMillan, E. A., Varble, A., Modell, J., Samai, P., Jiang, W. & Marraffini, L. A., Dec 1 2018, In : Nature Communications. 9, 1, 02557.

Research output: Contribution to journalArticle

CRISPR-Cas Systems
Clustered Regularly Interspaced Short Palindromic Repeats
Prophages
fitness
Bacteriophages

CRISPR-Cas systems exploit viral DNA injection to establish and maintain adaptive immunity

Modell, J., Jiang, W. & Marraffini, L. A., Apr 6 2017, In : Nature. 544, 7648, p. 101-104 4 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Viral DNA
Adaptive Immunity
Injections
Virus Diseases

Cas9 specifies functional viral targets during CRISPR-Cas adaptation

Heler, R., Samai, P., Modell, J., Weiner, C., Goldberg, G. W., Bikard, D. & Marraffini, L. A., Mar 12 2015, In : Nature. 519, 7542, p. 199-202 4 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Guide RNA
Immunologic Memory
Viral Genome
Streptococcus pyogenes

A DNA Damage-Induced, SOS-Independent Checkpoint Regulates Cell Division in Caulobacter crescentus

Modell, J., Kambara, T. K., Perchuk, B. S. & Laub, M. T., Jan 1 2014, In : PLoS Biology. 12, 10

Research output: Contribution to journalArticle

Caulobacter crescentus
Cell Division
DNA damage
DNA Damage
cell division

A DNA damage checkpoint in caulobacter crescentus inhibits cell division through a direct interaction with FtsW

Modell, J., Hopkins, A. C. & Laub, M. T., Jun 15 2011, In : Genes and Development. 25, 12, p. 1328-1343 16 p.

Research output: Contribution to journalArticle

Caulobacter crescentus
Cell Division
DNA Damage
Regulon
Constriction