Research Output 2002 2018

  • 86 Article
  • 6 Chapter
  • 2 Review article
  • 1 Conference contribution
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Article
2018

Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy

Wilson, D. R., Sen, R., Sunshine, J. C., Pardoll, D. M., Green, J. J. & Kim, Y. J. Feb 1 2018 In : Nanomedicine: Nanotechnology, Biology, and Medicine. 14, 2, p. 237-246 10 p.

Research output: Research - peer-reviewArticle

Immunotherapy
Nanoparticles
Neoplasms
Tumors
poly(beta-amino ester)
2017

Biodegradable and bioreducible poly(beta-amino ester) nanoparticles for intracellular delivery to treat brain cancer

Rui, Y., Quiñones, G. & Green, J. J. May 1 2017 In : AIChE Journal. 63, 5, p. 1470-1482 13 p.

Research output: Research - peer-reviewArticle

Brain Neoplasms
Nanoparticles
Small Interfering RNA
Polymers
DNA

Biomimetic biodegradable artificial antigen presenting cells synergize with PD-1 blockade to treat melanoma

Kosmides, A. K., Meyer, R. A., Hickey, J. W., Aje, K., Cheung, K. N., Green, J. J. & Schneck, J. P. Feb 1 2017 In : Biomaterials. 118, p. 16-26 11 p.

Research output: Research - peer-reviewArticle

Biomimetics
Antigen-Presenting Cells
Melanoma
Therapeutics
Tumors

Continuous microfluidic assembly of biodegradable poly(beta-amino ester)/DNA nanoparticles for enhanced gene delivery

Wilson, D. R., Mosenia, A., Suprenant, M. P., Upadhya, R., Routkevitch, D., Meyer, R. A., Quinones-Hinojosa, A. & Green, J. J. 2017 (Accepted/In press) In : Journal of Biomedical Materials Research - Part A.

Research output: Research - peer-reviewArticle

Microfluidics
Genes
Nanoparticles
DNA
poly(beta-amino ester)

Electrophoresis of cell membrane heparan sulfate regulates galvanotaxis in glial cells

Huang, Y. J., Schiapparelli, P., Kozielski, K., Green, J., Lavell, E., Guerrero-Cazares, H., Quinones-Hinojosa, A. & Searson, P. Aug 1 2017 In : Journal of Cell Science. 130, 15, p. 2459-2467 9 p.

Research output: Research - peer-reviewArticle

Heparitin Sulfate
Neuroglia
Electrophoresis
Cell Membrane
Neoplastic Stem Cells

Enhancing oligodendrocyte differentiation by transient transcription activation via DNA nanoparticle-mediated transfection

Li, X., Tzeng, S. Y., Zamboni, C. G., Koliatsos, V. E., Ming, G. L., Green, J. J. & Mao, H. Q. May 1 2017 In : Acta Biomaterialia. 54, p. 249-258 10 p.

Research output: Research - peer-reviewArticle

Transcription
Stem cells
DNA
Chemical activation
Nanoparticles

Noninvasive Targeted Transcranial Neuromodulation via Focused Ultrasound Gated Drug Release from Nanoemulsions

Airan, R. D., Meyer, R. A., Ellens, N. P. K., Rhodes, K. R., Farahani, K., Pomper, M. G., Kadam, S. D. & Green, J. J. Feb 8 2017 In : Nano Letters. 17, 2, p. 652-659 8 p.

Research output: Research - peer-reviewArticle

Brain
Ultrasonics
Nanoparticles
Pharmaceutical Preparations
seizures

Surface engineering for lymphocyte programming

Ben-Akiva, E., Meyer, R. A., Wilson, D. R. & Green, J. J. Feb 3 2017 (Accepted/In press) In : Advanced Drug Delivery Reviews.

Research output: Research - peer-reviewArticle

Lymphocyte Activation
Natural Killer Cells
B-Lymphocytes
Lymphocytes
T-Lymphocytes

Therapeutic potential of an anti-angiogenic multimodal biomimetic peptide in hepatocellular carcinoma

Barbhuiya, M. A., Mirando, A. C., Simons, B. W., Lemtiri-Chlieh, G., Green, J. J., Popel, A. S., Pandey, N. B. & Tran, P. T. Jan 1 2017 In : Oncotarget. 8, 60, p. 101520-101534 15 p.

Research output: Research - peer-reviewArticle

Biomimetics
Hepatocellular Carcinoma
Peptides
Therapeutics
Neoplasms

Tyrosine kinase blocking collagen IV-derived peptide suppresses ocular neovascularization and vascular leakage

Lima e Silva, R., Kanan, Y., Mirando, A. C., Kim, J., Shmueli, R. B., Lorenc, V. E., Fortmann, S. D., Sciamanna, J., Pandey, N. B., Green, J. J., Popel, A. S. & Campochiaro, P. A. Jan 18 2017 In : Science Translational Medicine. 9, 373, eaai8030

Research output: Research - peer-reviewArticle

Protein-Tyrosine Kinases
Vascular Endothelial Growth Factor A
Blood Vessels
Collagen
Peptides
2016

A Triple-Fluorophore-Labeled Nucleic Acid pH Nanosensor to Investigate Non-viral Gene Delivery

Wilson, D. R., Routkevitch, D., Rui, Y., Mosenia, A., Wahlin, K. J., Quinones-Hinojosa, A., Zack, D. J. & Green, J. J. Dec 2 2016 (Accepted/In press) In : Molecular Therapy.

Research output: Research - peer-reviewArticle

Nucleic Acids
Genes
DNA
Transfection
Nanoparticles

Gene delivery nanoparticles to modulate angiogenesis

Kim, J., Mirando, A. C., Popel, A. S. & Green, J. J. Jun 18 2016 (Accepted/In press) In : Advanced Drug Delivery Reviews.

Research output: Research - peer-reviewArticle

Nanoparticles
Genes
Genetic Therapy
Therapeutics
Angiogenesis Inducing Agents

Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours

Nailor, A. , Walker, D. A. , Jacques, T. S. , Warren, K. E. , Brem, H. , Kearns, P. R. , Greenwood, J. , Penny, J. I. , Pilkington, G. J. , Carcaboso, A. M. , Fleischhack, G. , Macarthur, D. , Slavc, I. , Meijer, L. , Gill, S. , Lowis, S. , Van Vuurden, D. G. , Pearl, M. S. , Clifford, S. C. , Morrissy, S. & 8 others Ivanov, D. P., Beccaria, K., Gilbertson, R. J., Straathof, K., Green, J. J., Smith, S., Rahman, R. & Kilday, J. P. Mar 31 2016 In : ecancermedicalscience. 10, 630

Research output: Research - peer-reviewArticle

Brain Neoplasms
Pediatrics
Education
Pharmaceutical Preparations
Neoplasms

Layer-by-layer inorganic/polymeric nanoparticles for kinetically controlled multigene delivery

Bishop, C. J., Liu, A. L., Lee, D. S., Murdock, R. J. & Green, J. J. Mar 1 2016 In : Journal of Biomedical Materials Research - Part A. 104, 3, p. 707-713 7 p.

Research output: Research - peer-reviewArticle

Genes
Nanoparticles
Gene therapy
Viruses
Plasmids

Nanoparticle-mediated conversion of primary human astrocytes into neurons and oligodendrocytes

Li, X., Kozielski, K., Cheng, Y. H., Liu, H., Zamboni, C. G., Green, J. & Mao, H. Q. Jul 1 2016 In : Biomaterials Science. 4, 7, p. 1100-1112 13 p.

Research output: Research - peer-reviewArticle

Neurons
Nanoparticles
Astrocytes
Neurology
Brain

Nanoparticle-mediated transcriptional modification enhances neuronal differentiation of human neural stem cells following transplantation in rat brain

Li, X., Tzeng, S. Y., Liu, X., Tammia, M., Cheng, Y. H., Rolfe, A., Sun, D., Zhang, N., Green, J. J., Wen, X. & Mao, H. Q. Apr 1 2016 In : Biomaterials. 84, p. 157-166 10 p.

Research output: Research - peer-reviewArticle

Neural Stem Cells
Stem Cell Transplantation
Nanoparticles
Stem Cells
Brain

Non-virally engineered human adipose mesenchymal stem cells produce BMP4, target brain tumors, and extend survival

Mangraviti, A., Tzeng, S. Y., Gullotti, D., Kozielski, K. L., Kim, J. E., Seng, M., Abbadi, S., Schiapparelli, P., Sarabia-Estrada, R., Vescovi, A., Brem, H., Olivi, A., Tyler, B., Green, J. J. & Quinones-Hinojosa, A. Sep 1 2016 In : Biomaterials. 100, p. 53-66 14 p.

Research output: Research - peer-reviewArticle

Bone Morphogenetic Protein 4
Mesenchymal Stromal Cells
Brain Neoplasms
Survival
Stem cells

Polymeric nanoparticles as cancer-specific DNA delivery vectors to human hepatocellular carcinoma

Zamboni, C. G., Kozielski, K. L., Vaughan, H. J., Nakata, M. M., Kim, J., Higgins, L. J., Pomper, M. G. & Green, J. J. Dec 1 2016 (Accepted/In press) In : Journal of Controlled Release.

Research output: Research - peer-reviewArticle

Nanoparticles
Hepatocellular Carcinoma
DNA
Neoplasms
Hepatocytes

Quantification of cellular and nuclear uptake rates of polymeric gene delivery nanoparticles and DNA plasmids via flow cytometry

Bishop, C. J., Majewski, R. L., Guiriba, T. R. M., Wilson, D. R., Bhise, N. S., Quiñones-Hinojosa, A. & Green, J. J. Jun 1 2016 In : Acta Biomaterialia. 37, p. 120-130 11 p.

Research output: Research - peer-reviewArticle

Flow cytometry
Plasmids
Genes
Nanoparticles
DNA

Shaping the future of nanomedicine: Anisotropy in polymeric nanoparticle design

Meyer, R. A. & Green, J. J. Mar 1 2016 In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 8, 2, p. 191-207 17 p.

Research output: Research - peer-reviewArticle

Nanomedicine
Anisotropy
Nanoparticles
Medical nanotechnology
Research

Synthesis and application of poly(ethylene glycol)-co-poly(β-amino ester) copolymers for small cell lung cancer gene therapy

Kim, J., Kang, Y., Tzeng, S. Y. & Green, J. J. Sep 1 2016 In : Acta Biomaterialia. 41, p. 293-301 9 p.

Research output: Research - peer-reviewArticle

Ethylene Glycol
Neoplasm Genes
Small Cell Lung Carcinoma
Genetic Therapy
Nanoparticles
2015
Stretching
Nanoparticles
Thin films
Biocompatible Materials
Biomaterials

Biodegradable Nanoellipsoidal Artificial Antigen Presenting Cells for Antigen Specific T-Cell Activation

Meyer, R. A., Sunshine, J. C., Perica, K., Kosmides, A. K., Aje, K., Schneck, J. P. & Green, J. J. Apr 1 2015 In : Small. 11, 13, p. 1519-1525 7 p.

Research output: Research - peer-reviewArticle

T-cells
Chemical activation
Antigens
Antigen-Presenting Cells
CD27 Antigens

Biodegradable polymer iron oxide nanocomposites: The future of biocompatible magnetism

Meyer, R. A. & Green, J. J. Dec 1 2015 In : Nanomedicine. 10, 23, p. 3421-3425 5 p.

Research output: Research - peer-reviewArticle

Biomimetic particles as therapeutics

Meyer, R. A., Sunshine, J. C. & Green, J. J. Sep 1 2015 In : Trends in Biotechnology. 33, 9

Research output: Research - peer-reviewArticle

Biomimetics
Therapeutics
Cell Membrane
Cell membranes
Artificial Cells

Degradable polymer-coated gold nanoparticles for co-delivery of DNA and siRNA

Bishop, C. J., Tzeng, S. Y. & Green, J. J. 2015 In : Acta Biomaterialia. 11, 1, p. 393-403 11 p.

Research output: Research - peer-reviewArticle

Gold
Nanoparticles
Small Interfering RNA
Polymers
DNA

Exploring the role of polymer structure on intracellular nucleic acid delivery via polymeric nanoparticles

Bishop, C. J., Kozielski, K. L. & Green, J. J. Dec 10 2015 In : Journal of Controlled Release. 219, p. 488-499 12 p.

Research output: Research - peer-reviewArticle

Nanoparticles
Nucleic Acids
Polymers
Genes
Nanomedicine

Gene delivery polymer structure-function relationships elucidated via principal component analysis

Bishop, C. J., Abubaker-Sharif, B., Guiriba, T., Tzeng, S. Y. & Green, J. J. Aug 4 2015 In : Chemical Communications. 51, 60, p. 12134-12137 4 p.

Research output: Research - peer-reviewArticle

Biocompatible Materials
Principal component analysis
Polymers
Genes
poly(beta-amino ester)

Platelet-Derived Growth Factor BB Enhances Osteogenesis of Adipose-Derived but Not Bone Marrow-Derived Mesenchymal Stromal/Stem Cells

Hung, B. P., Hutton, D. L., Kozielski, K. L., Bishop, C. J., Naved, B., Green, J. J., Caplan, A. I., Gimble, J. M., Dorafshar, A. H. & Grayson, W. L. Sep 1 2015 In : Stem Cells. 33, 9, p. 2773-2784 12 p.

Research output: Research - peer-reviewArticle

Mesenchymal Stromal Cells
Osteogenesis
Stem Cells
Bone Marrow
platelet-derived growth factor BB

Polymeric nanoparticles for nonviral gene therapy extend brain tumor survival in vivo

Mangraviti, A., Tzeng, S. Y., Kozielski, K. L., Wang, Y., Jin, Y., Gullotti, D., Pedone, M., Buaron, N., Liu, A., Wilson, D. R., Hansen, S. K., Rodriguez, F. J., Gao, G. D., Dimeco, F., Brem, H., Olivi, A., Tyler, B. & Green, J. J. Feb 24 2015 In : ACS Nano. 9, 2, p. 1236-1249 14 p.

Research output: Research - peer-reviewArticle

Gene therapy
Tumors
Brain
Nanoparticles
gene therapy

Targeted polymeric nanoparticles for cancer gene therapy

Kim, J., Wilson, D. R., Zamboni, C. G. & Green, J. J. Sep 14 2015 In : Journal of Drug Targeting. 23, 7-8, p. 627-641 15 p.

Research output: Research - peer-reviewArticle

Neoplasm Genes
Genetic Therapy
Nanoparticles
Neoplasms
Biocompatible Materials
2014

Biodegradable polymeric nanoparticles show high efficacy and specificity at DNA delivery to human glioblastoma in vitro and in vivo

Guerrero-Cázares, H., Tzeng, S. Y., Young, N. P., Abutaleb, A. O., Quiñones-Hinojosa, A. & Green, J. J. May 27 2014 In : ACS Nano. 8, 5, p. 5141-5153 13 p.

Research output: Research - peer-reviewArticle

delivery
tumors
deoxyribonucleic acid
nanoparticles
Tumors

Biomolecule delivery to engineer the cellular microenvironment for regenerative medicine

Bishop, C. J., Kim, J. & Green, J. J. 2014 In : Annals of Biomedical Engineering. 42, 7, p. 1557-1572 16 p.

Research output: Research - peer-reviewArticle

Biomolecules
Engineers
Regenerative Medicine
Cellular Microenvironment
Tissue engineering

Bioreducible cationic polymer-based nanoparticles for efficient and environmentally triggered cytoplasmic siRNA delivery to primary human brain cancer cells

Kozielski, K. L., Tzeng, S. Y., Hurtado De Mendoza, B. A. & Green, J. J. Apr 22 2014 In : ACS Nano. 8, 4, p. 3232-3241 10 p.

Research output: Research - peer-reviewArticle

brain
delivery
cancer
nanoparticles
polymers
Transfection
Polymers
Breast Neoplasms
poly(beta-amino ester)
Cells
Breast Neoplasms
Neoplasm Metastasis
Hypoxia
Neoplasms
Cell-Derived Microparticles

Particle shape dependence of CD8+ T cell activation by artificial antigen presenting cells

Sunshine, J. C., Perica, K., Schneck, J. P. & Green, J. J. 2014 In : Biomaterials. 35, 1, p. 269-277 9 p.

Research output: Research - peer-reviewArticle

T-cells
Chemical activation
Antigen-Presenting Cells
CD27 Antigens
Aspect ratio

Themed issue on nanoscale biomaterials

Green, J. J. & Burdick, J. A. 2014 In : Journal of Materials Chemistry B. 2, 46, p. 8039-8042 4 p.

Research output: Research - peer-reviewArticle

Biocompatible Materials
Vaccines
Therapeutics
Biomaterials
Nanostructures
2013

(3-Aminopropyl)-4-methylpiperazine end-capped poly(1,4-butanediol diacrylate-co-4-amino-1-butanol)-based multilayer films for gene delivery

Li, C., Tzeng, S. Y., Tellier, L. E. & Green, J. J. Jul 10 2013 In : ACS Applied Materials and Interfaces. 5, 13, p. 5947-5953 7 p.

Research output: Research - peer-reviewArticle

1-Butanol
Multilayer films
Genes
DNA
butanediol diacrylate

A bioreducible linear poly(β-amino ester) for siRNA delivery

Kozielski, K. L., Tzeng, S. Y. & Green, J. J. Jun 11 2013 In : Chemical Communications. 49, 46, p. 5319-5321 3 p.

Research output: Research - peer-reviewArticle

Cytotoxicity
Esters
Genes
Nanoparticles
Polymers

Bioengineered nanoparticles for siRNA delivery

Kozielski, K. L., Tzeng, S. Y. & Green, J. J. Sep 2013 In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 5, 5, p. 449-468 20 p.

Research output: Research - peer-reviewArticle

Nanoparticles
Small Interfering RNA
RNA
Biocompatible Materials
RNA Interference
Induced Pluripotent Stem Cells
Nanoparticles
Fibroblasts
Genes
poly(beta-amino ester)
Flow cytometry
Genes
Throughput
Nanoparticles
Flow Cytometry

Independent versus cooperative binding in polyethylenimine-DNA and poly(l-lysine)-DNA polyplexes

Ketola, T. M., Hanzlíková, M., Leppänen, L., Raviña, M., Bishop, C. J., Green, J. J., Urtti, A., Lemmetyinen, H., Yliperttula, M. & Vuorimaa-Laukkanen, E. Sep 12 2013 In : Journal of Physical Chemistry B. 117, 36, p. 10405-10413 9 p.

Research output: Research - peer-reviewArticle

Polyethyleneimine
DNA
DNA-lysine adduct
lysine
deoxyribonucleic acid

Long-term suppression of ocular neovascularization by intraocular injection of biodegradable polymeric particles containing aserpin-derived peptide

Shmueli, R. B., Ohnaka, M., Miki, A., Pandey, N. B., Lima e Silva, R., Koskimaki, J. E., Kim, J., Popel, A. S., Campochiaro, P. A. & Green, J. J. Oct 2013 In : Biomaterials. 34, 30, p. 7544-7551 8 p.

Research output: Research - peer-reviewArticle

Intraocular Injections
Macular Degeneration
Peptides
Therapeutics
Polymers

Nanoengineering approaches to the design of artificial antigen-presenting cells

Sunshine, J. C. & Green, J. J. Jul 2013 In : Nanomedicine. 8, 7, p. 1173-1189 17 p.

Research output: Research - peer-reviewArticle

Antigen-Presenting Cells
antigen
T-Lymphocytes
T-cells
key technology

Poly(β-amino ester) nanoparticle delivery of TP53 has activity against small cell lung cancer in vitro and in vivo

Kamat, C. D., Shmueli, R. B., Connis, N., Rudin, C. M., Green, J. J. & Hann, C. L. Apr 2013 In : Molecular Cancer Therapeutics. 12, 4, p. 405-415 11 p.

Research output: Research - peer-reviewArticle

Small Cell Lung Carcinoma
Nanoparticles
In Vitro Techniques
poly(beta-amino ester)
Polymers

SiRNA nanomedicine: The promise of bioreducible materials

Kozielski, K. L., Tzeng, S. Y. & Green, J. J. Jan 2013 In : Expert Review of Medical Devices. 10, 1, p. 7-10 4 p.

Research output: Research - peer-reviewArticle

Small Interfering RNA
Brain
Polymers
Nanoparticles
Degradation