John Tod Isaacs


1977 …2018
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Prostatic Neoplasms Medicine & Life Sciences
Androgens Medicine & Life Sciences
Prostate Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Androgen Receptors Medicine & Life Sciences
Cell Death Medicine & Life Sciences
Prostate-Specific Antigen Medicine & Life Sciences
Castration Medicine & Life Sciences

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Research Output 1977 2018

The what, when, and why of human prostate cancer xenografts

Brennen, W. & Isaacs, J. T., Jan 1 2018, (Accepted/In press) In : Prostate.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Precision Medicine
Genetic Heterogeneity

Mesenchymal stem cell infiltration during neoplastic transformation of the human prostate

Brennen, W., Zhang, B., Kulac, I., Kisteman, L. N., Antony, L., Wang, H., Meeker, A. K., Demarzo, A. M., Garraway, I. P., Denmeade, S. R. & Isaacs, J. T., 2017, In : Oncotarget. 8, 29, p. 46710-46727 18 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Prostatic Neoplasms

Rationale for bipolar androgen therapy (BAT) for metastatic prostate cancer

Isaacs, J. T., Brennen, W. & Denmeade, S. R., Aug 24 2017, (Accepted/In press) In : Cell Cycle. p. 1-2 2 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms

Analytic validation of RNA in situ hybridization (RISH) for AR and AR-V7 expression in human prostate cancer

Guedes, L. B., Morais, C. L., Almutairi, F., Haffner, M. C., Zheng, Q., Isaacs, J. T., Antonarakis, E., Lu, C., Tsai, H., Luo, J., Demarzo, A. M. & Lotan, T., Sep 15 2016, In : Clinical Cancer Research. 22, 18, p. 4651-4663 13 p.

Research output: Contribution to journalArticle

In Situ Hybridization
Prostatic Neoplasms

Androgen deprivation followed by acute androgen stimulation selectively sensitizes AR-positive prostate cancer cells to ionizing radiation

Hedayati, M., Haffner, M. C., Coulter, J. B., Raval, R. R., Zhang, Y., Zhou, H., Mian, O., Knight, E. J., Razavi, N., Dalrymple, S., Isaacs, J. T., Santos, A., Hales, R., Nelson, W. G., Yegnasubramanian, S. & DeWeese, T., Jul 1 2016, In : Clinical Cancer Research. 22, 13, p. 3310-3319 10 p.

Research output: Contribution to journalArticle

Ionizing Radiation
Prostatic Neoplasms