John Tod Isaacs


1977 …2020

Research output per year

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Research Output

Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress

Nyquist, M. D., Corella, A., Coleman, I., De Sarkar, N., Kaipainen, A., Ha, G., Gulati, R., Ang, L., Chatterjee, P., Lucas, J., Pritchard, C., Risbridger, G., Isaacs, J., Montgomery, B., Morrissey, C., Corey, E. & Nelson, P. S., May 26 2020, In : Cell Reports. 31, 8, 107669.

Research output: Contribution to journalArticle

Open Access
  • Open Access
  • A Phase I Study to Assess the Safety and Cancer-Homing Ability of Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells in Men with Localized Prostate Cancer

    Schweizer, M. T., Wang, H., Bivalacqua, T. J., Partin, A. W., Lim, S. J., Chapman, C., Abdallah, R., Levy, O., Bhowmick, N. A., Karp, J. M., De Marzo, A., Isaacs, J. T., Brennen, W. N. & Denmeade, S. R., May 2019, In : Stem Cells Translational Medicine. 8, 5, p. 441-449 9 p.

    Research output: Contribution to journalArticle

    Open Access
  • Asporin restricts mesenchymal stromal cell differentiation, alters the tumor microenvironment, and drives metastatic progression

    Hughes, R. M., Simons, B. W., Khan, H., Miller, R., Kugler, V., Torquato, S., Theodros, D., Haffner, M. C., Lotan, T., Huang, J., Davicioni, E., An, S. S., Riddle, R. C., Thorek, D. L. J., Garraway, I. P., Fertig, E. J., Isaacs, J. T., Nathaniel Brennen, W., Park, B. H. & Hurley, P. J., 2019, In : Cancer Research. 79, 14, p. 3636-3650 15 p.

    Research output: Contribution to journalArticle

    Open Access
  • Establishing a cryopreservation protocol for patient-derived xenografts of prostate cancer

    Porter, L. H., Lawrence, M. G., Wang, H., Clark, A. K., Bakshi, A., Obinata, D., Goode, D., Papargiris, M., Mural, Clouston, D., Ryan, A., Norden, S., Corey, E., Nelson, P. S., Isaacs, J. T., Grummet, J., Kourambas, J., Sandhu, S., Murphy, D. G., Pook, D. & 3 others, Frydenberg, M., Taylor, R. A. & Risbridger, G. P., Aug 1 2019, In : Prostate. 79, 11, p. 1326-1337 12 p.

    Research output: Contribution to journalArticle