John Tod Isaacs

Professor

1977 …2019
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Fingerprint Dive into the research topics where John Tod Isaacs is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Prostatic Neoplasms Medicine & Life Sciences
Androgens Medicine & Life Sciences
Prostate Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Androgen Receptors Medicine & Life Sciences
Cell Death Medicine & Life Sciences
Prostate-Specific Antigen Medicine & Life Sciences
Castration Medicine & Life Sciences

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Research Output 1977 2019

Open Access
Mesenchymal Stromal Cells
Prostatic Neoplasms
Bone Marrow
Safety
Neoplasms

Asporin restricts mesenchymal stromal cell differentiation, alters the tumor microenvironment, and drives metastatic progression

Hughes, R. M., Simons, B. W., Khan, H., Miller, R., Kugler, V., Torquato, S., Theodros, D., Haffner, M. C., Lotan, T., Huang, J., Davicioni, E., An, S. S., Riddle, R. C., Thorek, D. L. J., Garraway, I. P., Fertig, E. J., Isaacs, J. T., Nathaniel Brennen, W., Park, B. H. & Hurley, P. J., Jan 1 2019, In : Cancer Research. 79, 14, p. 3636-3650 15 p.

Research output: Contribution to journalArticle

Open Access
Tumor Microenvironment
Mesenchymal Stromal Cells
Cell Differentiation
Neoplasms
Neoplasm Metastasis

Establishing a cryopreservation protocol for patient-derived xenografts of prostate cancer

Porter, L. H., Lawrence, M. G., Wang, H., Clark, A. K., Bakshi, A., Obinata, D., Goode, D., Papargiris, M., Mural, Clouston, D., Ryan, A., Norden, S., Corey, E., Nelson, P. S., Isaacs, J. T., Grummet, J., Kourambas, J., Sandhu, S., Murphy, D. G., Pook, D. & 3 others, Frydenberg, M., Taylor, R. A. & Risbridger, G. P., Aug 1 2019, In : Prostate. 79, 11, p. 1326-1337 12 p.

Research output: Contribution to journalArticle

Cryopreservation
Heterografts
Prostatic Neoplasms
Freezing
rho-Associated Kinases
Open Access
Mesenchymal Stromal Cells
Pharmaceutical Preparations
Neoplasms

Pharmacologic exhaustion of suppressor cells with tasquinimod enhances bacterial clearance during tuberculosis

Gupta, S., Krug, S., Pokkali, S., Leanderson, T., Isaacs, J. T., Srikrishna, G. & Bishai, W. R., Feb 1 2019, In : American Journal of Respiratory and Critical Care Medicine. 199, 3, p. 386-389 4 p.

Research output: Contribution to journalLetter

Tuberculosis
tasquinimod