John L Goodier

Assistant Professor

1981 …2020

Research output per year

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Research Output

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2019

A human endogenous retrovirus encoded protease potentially cleaves numerous cellular proteins

Rigogliuso, G., Biniossek, M. L., Goodier, J. L., Mayer, B., Pereira, G. C., Schilling, O., Meese, E. & Mayer, J., Aug 22 2019, In : Mobile DNA. 10, 1, 36.

Research output: Contribution to journalArticle

Open Access

Mobile DNA in Endocrinology: LINE-1 Retrotransposon Causing Partial Androgen Insensitivity Syndrome

Batista, R. L., Yamaguchi, K., Rodrigues, A. D. S., Nishi, M. Y., Goodier, J. L., Carvalho, L. R., Domenice, S., Costa, E. M. F., Kazazian, H. H. & Mendonca, B. B., Dec 1 2019, In : Journal of Clinical Endocrinology and Metabolism. 104, 12, p. 6385-6390 6 p.

Research output: Contribution to journalArticle

2018

Meeting report: Mobile genetic elements and genome plasticity 2018

Abrams, J. M., Arkhipova, I. R., Belfort, M., Boeke, J. D., Joan Curcio, M., Faulkner, G. J., Goodier, J. L., Lehmann, R. & Levin, H. L., Jun 22 2018, In : Mobile DNA. 9, 1, 21.

Research output: Contribution to journalArticle

Properties of LINE-1 proteins and repeat element expression in the context of amyotrophic lateral sclerosis

Pereira, G. C., Sanchez, L., Schaughency, P. M., Rubio-Roldán, A., Choi, J. A., Planet, E., Batra, R., Turelli, P., Trono, D., Ostrow, L. W., Ravits, J., Kazazian, H. H., Wheelan, S. J., Heras, S. R., Mayer, J., García-Pérez, J. L. & Goodier, J. L., Dec 15 2018, In : Mobile DNA. 9, 1, 35.

Research output: Contribution to journalArticle

Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins

Mayer, J., Harz, C., Sanchez, L., Pereira, G. C., Maldener, E., Heras, S. R., Ostrow, L. W., Ravits, J., Batra, R., Meese, E., García-Pérez, J. L. & Goodier, J. L., Aug 2 2018, In : Molecular neurodegeneration. 13, 1, 39.

Research output: Contribution to journalArticle

2017

Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion

Li, P., Du, J., Goodier, J. L., Hou, J., Kang, J., Kazazian, H., Zhao, K. & Yu, X. F., 2017, In : Nucleic Acids Research. 45, 8, p. 4619-4631 13 p.

Research output: Contribution to journalArticle

Engineered LINE-1 retrotransposition in nondividing human neurons

MacIa, A., Widmann, T. J., Heras, S. R., Ayllon, V., Sanchez, L., Benkaddour-Boumzaouad, M., Muñoz-Lopez, M., Rubio, A., Amador-Cubero, S., Blanco-Jimenez, E., Garcia-Castro, J., Menendez, P., Ng, P., Muotri, A. R., Goodier, J. L. & Garcia-Perez, J. L., Mar 2017, In : Genome research. 27, 3, p. 335-348 14 p.

Research output: Contribution to journalArticle

2015

The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition

Goodier, J. L., Pereira, G. C., Cheung, L. E., Rose, R. J. & Kazazian, H. H., May 1 2015, In : PLoS genetics. 11, 5, e1005252.

Research output: Contribution to journalArticle

2013

In vitro screening for compounds that enhance human L1 mobilization.

Terasaki, N., Goodier, J. L., Cheung, L. E., Wang, Y. J., Kajikawa, M., Kazazian, H. H. & Okada, N., 2013, In : PloS one. 8, 9

Research output: Contribution to journalArticle

Open Access

Mapping the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition

Goodier, J. L., Cheung, L. E. & Kazazian, H. H., Aug 1 2013, In : Nucleic acids research. 41, 15, p. 7401-7419 19 p.

Research output: Contribution to journalArticle

Modulation of LINE-1 and Alu/SVA Retrotransposition by Aicardi-Goutières Syndrome-Related SAMHD1

Zhao, K., Du, J., Han, X., Goodier, J. L., Li, P., Zhou, X., Wei, W., Evans, S. L., Li, L., Zhang, W., Cheung, L. E., Wang, G., Kazazian, H. H. & Yu, X. F., Sep 26 2013, In : Cell Reports. 4, 6, p. 1108-1115 8 p.

Research output: Contribution to journalArticle

2012

MOV10 RNA Helicase Is a Potent Inhibitor of Retrotransposition in Cells

Goodier, J. L., Cheung, L. E. & Kazazian, H. H., Oct 1 2012, In : PLoS genetics. 8, 10, e1002941.

Research output: Contribution to journalArticle

2011

Retrotransposition of marked SVA elements by human L1s in cultured cells

Hancks, D. C., Goodier, J. L., Mandal, P. K., Cheung, L. E. & Kazazian, H. H., Sep 1 2011, In : Human molecular genetics. 20, 17, p. 3386-3400 15 p., ddr245.

Research output: Contribution to journalArticle

2010

Discrete subcellular partitioning of human retrotransposon RNAs despite a common mechanism of genome insertion

Goodier, J. L., Mandal, P. K., Zhang, L. & Kazazian, H. H., Feb 10 2010, In : Human molecular genetics. 19, 9, p. 1712-1725 14 p., ddq048.

Research output: Contribution to journalArticle

2007
2004

A potential role for the nucleous in L1 retrotransposition

Goodier, J. L., Ostertag, E. M., Engleka, K. A., Seleme, M. C. & Kazazian, H. H., May 15 2004, In : Human molecular genetics. 13, 10, p. 1041-1048 8 p.

Research output: Contribution to journalArticle

2003

SVA Elements Are Nonautonomous Retrotransposons that Cause Disease in Humans

Ostertag, E. M., Goodier, J. L., Zhang, Y. & Kazazian, H. H., Dec 2003, In : American journal of human genetics. 73, 6, p. 1444-1451 8 p.

Research output: Contribution to journalArticle

2002

A mouse model of human L1 retrotransposition

Ostertag, E. M., DeBerardinis, R. J., Goodier, J. L., Zhang, Y., Yang, N., Gerton, G. L. & Kazazian, H. H., Dec 1 2002, In : Nature genetics. 32, 4, p. 655-660 6 p.

Research output: Contribution to journalArticle

2001

A novel active L1 retrotransposon subfamily in the mouse

Goodier, J. L., Ostertag, E. M., Du, K. & Kazazian, J., Nov 20 2001, In : Genome research. 11, 10, p. 1677-1685 9 p.

Research output: Contribution to journalArticle

2000

Control of transfer RNA maturation by phosphorylation of the human La antigen on serine 366

Intine, R. V. A., Sakulich, A. L., Koduru, S. B., Huang, Y., Pierstorff, E., Goodier, J. L., Phan, L. & Maraia, R. J., Aug 2000, In : Molecular cell. 6, 2, p. 339-348 10 p.

Research output: Contribution to journalArticle

Open Access

Transduction of 3'-flanking sequences is common in L1 retrotransposition

Goodier, J. L., Ostertag, E. M. & Kazazian, H. H., Mar 1 2000, In : Human molecular genetics. 9, 4, p. 653-657 5 p.

Research output: Contribution to journalArticle

Open Access
1998

5' Processing of tRNA precursors can be modulated by the human La antigen phosphoprotein

Fan, H., Goodier, J. L., Chamberlain, J. R., Engelke, D. R. & Maraia, R. J., Jun 1998, In : Molecular and cellular biology. 18, 6, p. 3201-3211 11 p.

Research output: Contribution to journalArticle

Open Access

Characterization of novel minisatellite repeat loci in Atlantic salmon (Salmo salar) and their phylogenetic distribution

Goodier, J. L. & Davidson, W. S., Mar 2 1998, In : Journal of Molecular Evolution. 46, 2, p. 245-255 11 p.

Research output: Contribution to journalArticle

Rapid amplification of a retrotransposon subfamily is evolving the mouse genome

DeBerardinis, R. J., Goodier, J. L., Ostertag, E. M. & Kazazian, H. H., Nov 17 1998, In : Nature genetics. 20, 3, p. 288-290 3 p.

Research output: Contribution to journalArticle

1997

A carboxy-terminal basic region controls RNA polymerase III transcription factor activity of human la protein

Goodier, J. L., Fan, H. & Maraia, R. J., Oct 1997, In : Molecular and cellular biology. 17, 10, p. 5823-5832 10 p.

Research output: Contribution to journalArticle

Open Access

Phosphorylation of the human La antigen on serine 366 can regulate recycling of RNA polymerase III transcription complexes

Hao, F., Sakulich, A. L., Goodier, J. L., Zhang, X., Jun, Q. & Maraia, R. J., Mar 7 1997, In : Cell. 88, 5, p. 707-715 9 p.

Research output: Contribution to journalArticle

1995
1994

Characterization of a repetitive element detected by NheI in the genomes of Salmo species

Goodier, J. L. & Davidson, W. S., Jan 1 1994, In : Genome. 37, 4, p. 639-645 7 p.

Research output: Contribution to journalArticle

Tc1 transposon-like sequences are widely distributed in salmonids

Goodier, J. L. & Davidson, W. S., Aug 4 1994, In : Journal of molecular biology. 241, 1, p. 26-34 9 p.

Research output: Contribution to journalArticle

1993

A repetitive element in the genome of Atlantic salmon, Salmo salar

Goodier, J. L. & Davidson, W. S., Sep 15 1993, In : Gene. 131, 2, p. 237-242 6 p.

Research output: Contribution to journalArticle

Cytogenetic effects of hydrostatic pressure treatment to suppress the first cleavage of salmon embryos

Yamazaki, F. & Goodier, J., Feb 15 1993, In : Aquaculture. 110, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

1990

The occurrence of cyprinidae and other small fish species in relation to pH in Ontario lakes

Matuszek, J. E., Goodier, J. & Wales, D. L., Sep 1990, In : Transactions of the American Fisheries Society. 119, 5, p. 850-861 12 p.

Research output: Contribution to journalArticle

1987

An Assessment of the Effects of Climate Warming on Great Lakes Basin Fishes

Meisner, J. D., Goodier, J. L., Regier, H. A., Shuter, B. J. & Christie, W. J., Jan 1 1987, In : Journal of Great Lakes Research. 13, 3, p. 340-352 13 p.

Research output: Contribution to journalArticle

1984

The Nineteenth‐Century Fisheries of the Hudson's Bay Company Trading Posts on Lake Superior: a Biogeographical Study

Goodier, J. L., Dec 1984, Canadian Geographer / Le Géographe canadien, 28, 4, p. 341-357 17 p.

Research output: Contribution to specialist publicationArticle

1981