Research Output 1977 2017

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Article
2017
Image-Guided Biopsy
Amides
Glioma
Protons
Magnetic Resonance Spectroscopy
Prostate-Specific Antigen
Glioma
Membranes
Astrocytoma
Residual Neoplasm
2016

A monoclonal antibody against KCNK9 K+ channel extracellular domain inhibits tumour growth and metastasis

Sun, H., Luo, L., Lal, B., Ma, X., Chen, L., Hann, C. L., Fulton, A. M., Leahy, D. J., Laterra, J. & Li, M. Feb 4 2016 In : Nature Communications. 7, 10339

Research output: Contribution to journalArticle

Cell Survival
Monoclonal Antibodies
Neoplasm Metastasis
Carcinoma
Antibodies

Epigenetic modulation of a miR-296-5p: HMGA1 axis regulates Sox2 expression and glioblastoma stem cells

Lopez-Bertoni, H., Lal, B., Michelson, N., Guerrero-Cázares, H., Quiñones-Hinojosa, A., Li, Y. & Laterra, J. Feb 22 2016 In : Oncogene.

Research output: Contribution to journalArticle

Glioblastoma
Epigenomics
Stem Cells
Neoplasms
Neoplastic Stem Cells

Microarray-based phospho-proteomic profiling of complex biological systems

Goodwin, C. R., Woodard, C. L., Zhou, X., Pan, J., Olivi, A., Xia, S., Bettegowda, C., Sciubba, D. M., Pevsner, J., Zhu, H. & Laterra, J. Apr 1 2016 In : Translational Oncology. 9, 2, p. 124-129 6 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Proteomics
Phosphotransferases
Neoplasms
Tumor Microenvironment

Regulation of Glioblastoma Tumor-Propagating Cells by the Integrin Partner Tetraspanin CD151

Tilghman, J., Schiapparelli, P., Lal, B., Ying, M., Quinones-Hinojosa, A., Xia, S. & Laterra, J. 2016 In : Neoplasia. 18, 3, p. 185-198 14 p.

Research output: Contribution to journalArticle

Glioblastoma
Integrins
Stem Cells
Neoplasms
Cell Movement
dendrimers
Dendrimers
saturation
acids
Salicylic acid

Tumor microenvironment tenascin-C promotes glioblastoma invasion and negatively regulates tumor proliferation

Xia, S., Lal, B., Tung, B., Wang, S., Goodwin, C. R. & Laterra, J. Apr 1 2016 In : Neuro-Oncology. 18, 4, p. 507-517 11 p.

Research output: Contribution to journalArticle

Tenascin
Tumor Microenvironment
Glioblastoma
Neoplasms
Brain Neoplasms

Updates from the Neuro-Oncology section of the 2015 American Neurological Association annual meeting

Lukas, R. V., Wainwright, D. A. & Laterra, J. J. Jan 1 2016 In : Future Oncology. 12, 2, p. 143-147 5 p.

Research output: Contribution to journalArticle

Immunotherapy
National Institute of Neurological Disorders and Stroke
Neurocutaneous Syndromes
Dioxygenases
Tuberous Sclerosis
2015

DNMT-dependent suppression of microRNA regulates the induction of GBM tumor-propagating phenotype by Oct4 and Sox2

Lopez-Bertoni, H., Lal, B., Li, A., Caplan, M., Guerrero-Cázares, H., Eberhart, C. G., Quiñones-Hinojosa, A., Glas, M., Scheffler, B., Laterra, J. & Li, Y. Jul 23 2015 In : Oncogene. 34, 30, p. 3994-4004 11 p.

Research output: Contribution to journalArticle

Transferases
MicroRNAs
Phenotype
DNA
Neoplasms
Blood Volume
Blood-Brain Barrier
Brain Neoplasms
Glucose
Area Under Curve

Extraneural Glioblastoma Multiforme Vertebral Metastasis

Goodwin, C. R., Liang, L., Abu-Bonsrah, N., Hdeib, A., Elder, B. D., Kosztowski, T., Bettegowda, C., Laterra, J., Burger, P. & Sciubba, D. M. Aug 21 2015 In : World Neurosurgery.

Research output: Contribution to journalArticle

Glioblastoma
Neoplasm Metastasis
Central Nervous System Neoplasms
Neurologic Manifestations
Autopsy

Identification of Global DNA Methylation Signatures in Glioblastoma-Derived Cancer Stem Cells

Lee, E. J., Rath, P., Liu, J., Ryu, D., Pei, L., Noonepalle, S. K., Shull, A. Y., Feng, Q., Litofsky, N. S., Miller, D. C., Anthony, D. C., Kirk, M. D., Laterra, J., Deng, L., Xin, H. B., Wang, X., Choi, J. H. & Shi, H. Jul 20 2015 In : Journal of Genetics and Genomics. 42, 7, p. 355-371 17 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
DNA Methylation
Glioblastoma
Neoplasms
Epigenomics
Noise
Glioblastoma
Principal Component Analysis
Protons
Neoplasms

Parallel reconstruction in accelerated multivoxel MR spectroscopy

Boer, V. O., Klomp, D. W. J., Laterra, J. & Barker, P. B. Sep 1 2015 In : Magnetic Resonance in Medicine. 74, 3, p. 599-606 8 p.

Research output: Contribution to journalArticle

Magnetic Resonance Spectroscopy
Oligodendroglioma
Motor Cortex
Artifacts
Noise
Prolactinoma
Retreatment
Pituitary Neoplasms
Prolactin
Salvage Therapy
2014

HMMR maintains the stemness and tumorigenicity of glioblastoma stem-like cells

Tilghman, J., Wu, H., Sang, Y., Shi, X., Guerrero-Cazares, H., Quinones-Hinojosa, A., Eberhart, C. G., Laterra, J. & Ying, M. Jun 1 2014 In : Cancer Research. 74, 11, p. 3168-3179 12 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Glioblastoma
Stem Cells
Neoplasms
Neoplastic Stem Cells

Kruppel-like factor-9 (KLF9) inhibits glioblastoma stemness through global transcription repression and integrin α6 inhibition

Ying, M., Tilghman, J., Wei, Y., Guerrero-Cazares, H., Quinones-Hinojosa, A., Ji, H. & Laterra, J. Nov 21 2014 In : Journal of Biological Chemistry. 289, 47, p. 32742-32756 15 p.

Research output: Contribution to journalArticle

Kruppel-Like Transcription Factors
Glioblastoma
Integrins
Cell Differentiation
Carcinogenesis

Lipid metabolism enzyme ACSVL3 supports glioblastoma stem cell maintenance and tumorigenicity

Sun, P., Xia, S., Lal, B., Shi, X., Yang, K. S., Watkins, P. A. & Laterra, J. Jun 4 2014 In : BMC Cancer. 14, 1, 401

Research output: Contribution to journalArticle

Coenzyme A Ligases
Glioblastoma
Lipid Metabolism
Stem Cells
Enzymes
Pluripotent Stem Cells
Dopaminergic Neurons
Transcription Factors
Parkinson Disease
Neurons

Quantitative multiparametric MRI assessment of glioma response to radiotherapy in a rat model

Hong, X., Liu, L., Wang, M., Ding, K., Fan, Y., Ma, B., Lal, B., Tyler, B., Mangraviti, A., Wang, S., Wong, J., Laterra, J. & Zhou, J. 2014 In : Neuro-Oncology. 16, 6, p. 856-867 12 p.

Research output: Contribution to journalArticle

Glioma
Radiotherapy
Neoplasms
Amides
Protons
2013

In vivo c-Met pathway inhibition depletes human glioma xenografts of tumor-propagating stem-like cells

Rath, P., Lal, B., Ajala, O., Li, Y., Xia, S., Kim, J. & Laterra, J. Apr 2013 In : Translational Oncology. 6, 2, p. 104-111 8 p.

Research output: Contribution to journalArticle

Heterografts
Glioma
Stem Cells
Neoplasms
Neoplastic Stem Cells

Profiling the dynamics of a human phosphorylome reveals new components in HGF/c-Met signaling.

Woodard, C. L., Goodwin, C. R., Wan, J., Xia, S., Newman, R., Hu, J., Zhang, J., Hayward, S. D., Qian, J., Laterra, J. & Zhu, H. 2013 In : PLoS One. 8, 9, e72671

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Proteins
proteins
Phosphorylation
protein phosphorylation
Gadolinium
Amides
Glioma
Protons
Brain
2012

Cancer stem cells: Distinct entities or dynamically regulated phenotypes?

Li, Y. & Laterra, J. Feb 1 2012 In : Cancer Research. 72, 3, p. 576-580 5 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Phenotype
Neoplasms
Stem Cells
Cues

Collagen IV and CXC chemokine-derived antiangiogenic peptides suppress glioma xenograft growth

Rosca, E. V., Lal, B., Koskimaki, J. E., Popel, A. S. & Laterra, J. Aug 2012 In : Anti-Cancer Drugs. 23, 7, p. 706-712 7 p.

Research output: Contribution to journalArticle

CXC Chemokines
Heterografts
Glioma
Collagen
Peptides

EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase

Wang, S. D., Rath, P., Lal, B., Richard, J. P., Li, Y., Goodwin, C. R., Laterra, J. & Xia, S. Dec 13 2012 In : Oncogene. 31, 50, p. 5132-5143 12 p.

Research output: Contribution to journalArticle

EphB2 Receptors
Focal Adhesion Protein-Tyrosine Kinases
Glioblastoma
Cell Movement
Neoplasms

Evaluation of radiation necrosis and malignant glioma in rat models using diffusion tensor MR imaging

Wang, S., Chen, Y., Lal, B., Ford, E., Tryggestad, E., Armour, M., Yan, K., Laterra, J. & Zhou, J. Mar 2012 In : Journal of Neuro-Oncology. 107, 1, p. 51-60 10 p.

Research output: Contribution to journalArticle

Diffusion Tensor Imaging
Glioma
Necrosis
Radiation
Neoplasms

Influence of bioluminescence imaging dynamics by dluciferin uptake and efflux mechanisms

Zhang, Y., Pullambhatla, M., Laterra, J. & Pomper, M. G. Nov 2012 In : Molecular Imaging. 11, 6, p. 499-506 8 p.

Research output: Contribution to journalArticle

bioluminescence
Bioluminescence
Imaging techniques
Luciferases
efflux
Neoplastic Stem Cells
DNA-Binding Proteins
Glioblastoma
Transcription Factors
Stem Cells
2011

A phase II study evaluating the efficacy and safety of AMG 102 (rilotumumab) in patients with recurrent glioblastoma

Wen, P. Y., Schiff, D., Cloughesy, T. F., Raizer, J. J., Laterra, J., Smitt, M., Wolf, M., Oliner, K. S., Anderson, A., Zhu, M., Loh, E. & Reardon, D. A. Apr 2011 In : Neuro-Oncology. 13, 4, p. 437-446 10 p.

Research output: Contribution to journalArticle

Glioblastoma
Safety
Hepatocyte Growth Factor
Disease-Free Survival
Gliosarcoma

c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype

Li, Y., Li, A., Glas, M., Lal, B., Ying, M., Sang, Y., Xia, S., Trageser, D., Guerrero-Cázares, H., Eberhart, C. G., Quiñones-Hinojosa, A., Scheffler, B. & Laterra, J. Jun 14 2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 24, p. 9951-9956 6 p.

Research output: Contribution to journalArticle

Glioblastoma
Phenotype
Neoplastic Stem Cells
Transcription Factors
Stem Cells

Differentiation between glioma and radiation necrosis using molecular magnetic resonance imaging of endogenous proteins and peptides

Zhou, J., Tryggestad, E., Wen, Z., Lal, B., Zhou, T., Grossman, R., Wang, S., Yan, K., Fu, D. X., Ford, E., Tyler, B., Blakeley, J., Laterra, J. & Van Zijl, P. C. M. Jan 2011 In : Nature Medicine. 17, 1, p. 130-134 5 p.

Research output: Contribution to journalArticle

Amides
Glioma
Protons
Necrosis
Magnetic Resonance Imaging

Krüppel-like family of transcription factor 9, a differentiation- associated transcription factor, suppresses Notch1 signaling and inhibits glioblastoma-initiating stem cells

Ying, M., Sang, Y., Li, Y., Guerrero-Cazares, H., Quinones-Hinojosa, A., Vescovi, A. L., Eberhart, C. G., Xia, S. & Laterra, J. Jan 2011 In : Stem Cells. 29, 1, p. 20-31 12 p.

Research output: Contribution to journalArticle

Kruppel-Like Transcription Factors
Neoplastic Stem Cells
Glioblastoma
Transcription Factors
Stem Cells

PTEN reconstitution alters glioma responses to c-Met pathway inhibition

Rory Goodwin, C., Lal, B., Ho, S., Woodard, C. L., Zhou, X., Taeger, A., Xia, S. & Laterra, J. Oct 2011 In : Anti-Cancer Drugs. 22, 9, p. 905-912 8 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Glioma
Heterografts
Receptor Protein-Tyrosine Kinases
Cell Line

Regulation of glioblastoma stem cells by retinoic acid: Role for Notch pathway inhibition

Ying, M., Wang, S., Sang, Y., Sun, P., Lal, B., Goodwin, C. R., Guerrero-Cazares, H., Quinones-Hinojosa, A., Laterra, J. & Xia, S. Aug 4 2011 In : Oncogene. 30, 31, p. 3454-3467 14 p.

Research output: Contribution to journalArticle

Glioblastoma
Tretinoin
Stem Cells
Inhibition (Psychology)
Neoplastic Stem Cells

Tumor-specific imaging through progression elevated gene-3 promoter-driven gene expression

Bhang, H. E. C., Gabrielson, K. L., Laterra, J., Fisher, P. B. & Pomper, M. G. Jan 2011 In : Nature Medicine. 17, 1, p. 123-129 7 p.

Research output: Contribution to journalArticle

Gene Expression
Genes
Neoplasms
Adenofibroma
Cyclic AMP Receptor Protein
2010

Cyr61 mediates hepatocyte growth factor-dependent tumor cell growth, migration, and Akt activation

Goodwin, C. R., Lal, B., Zhou, X., Ho, S., Xia, S., Taeger, A., Murray, J. & Laterra, J. Apr 1 2010 In : Cancer Research. 70, 7, p. 2932-2941 10 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Cell Movement
Neoplasms
Glioma
Small Interfering RNA

FasL gene knock-down therapy enhances the antiglioma immune response

Jansen, T., Tyler, B., Mankowski, J. L., Recinos, V. R., Pradilla, G., Legnani, F., Laterra, J. & Olivi, A. May 2010 In : Neuro-Oncology. 12, 5, p. 482-489 8 p.

Research output: Contribution to journalArticle

Gene Knockdown Techniques
Glioma
Neoplasms
T-Lymphocytes
Neuroglia

Molecular therapy targeting Sonic hedgehog and hepatocyte growth factor signaling in a mouse model of medulloblastoma

Coon, V., Laukert, T., Pedone, C. A., Laterra, J., Kim, K. J. & Fults, D. W. Sep 2010 In : Molecular Cancer Therapeutics. 9, 9, p. 2627-2636 10 p.

Research output: Contribution to journalArticle

Medulloblastoma
Hepatocyte Growth Factor
Hedgehogs
Neoplasms
Neutralizing Antibodies

Neuro-oncology: Unmasking the multiforme in glioblastoma

Goodwin, C. R. & Laterra, J. Jun 2010 In : Nature Reviews Neurology. 6, 6, p. 304-305 2 p.

Research output: Contribution to journalArticle

Prognostic significance of contrast-enhancing anaplastic astrocytomas in adults

Chaichana, K. L., Kosztowski, T., Niranjan, A. N. I., Olivi, A., Weingart, J. D., Laterra, J., Brem, H. & Quiñones-Hinojosa, A. Aug 2010 In : Journal of Neurosurgery. 113, 2, p. 286-292 7 p.

Research output: Contribution to journalArticle

Astrocytoma
Recurrence
Neoplasms
Craniotomy
Disease-Free Survival

Recurrence and malignant degeneration after resection of adult hemispheric low-grade gliomas: Clinical article

Chaichana, K. L., McGirt, M. J., Laterra, J., Olivi, A. & Quiñones-Hinojosa, A. Jan 2010 In : Journal of Neurosurgery. 112, 1, p. 10-17 8 p.

Research output: Contribution to journalArticle

Glioma
Recurrence
Neoplasms
Astrocytoma
Oligodendroglioma

Scatter factor protects tumor cells against apoptosis caused by TRAIL

Fan, S., Meng, Q., Laterra, J. J. & Rosen, E. M. Jan 2010 In : Anti-Cancer Drugs. 21, 1, p. 10-24 15 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Apoptosis
Neoplasms
Death Domain Receptor Signaling Adaptor Proteins
Proto-Oncogene Proteins c-met
2009

Acyl-CoA synthetase VL3 knockdown inhibits human glioma cell proliferation and tumorigenicity

Pei, Z., Sun, P., Huang, P., Lal, B., Laterra, J. & Watkins, P. A. Dec 15 2009 In : Cancer Research. 69, 24, p. 9175-9182 8 p.

Research output: Contribution to journalArticle

Coenzyme A Ligases
Glioma
Cell Proliferation
Heterografts
Receptor Protein-Tyrosine Kinases

Camptothecin and Fas receptor agonists synergistically induce medulloblastoma cell death: ROS-dependent mechanisms

Li, Y., Rory Goodwin, C., Sang, Y., Rosen, E. M., Laterra, J. & Xia, S. Oct 2009 In : Anti-Cancer Drugs. 20, 9, p. 770-778 9 p.

Research output: Contribution to journalArticle

CD95 Antigens
Camptothecin
Medulloblastoma
Cell Death
Apoptosis

DNER, an epigenetically modulated gene, regulates glioblastoma-derived neurosphere cell differentiation and tumor propagation

Sun, P., Xia, S., Lal, B., Eberhart, C. G., Quinones-Hinojosa, A., Maciaczyk, J., Matsui, W., DiMeco, F., Piccirillo, S. M., Vescovi, A. L. & Laterra, J. Jul 2009 In : Stem Cells. 27, 7, p. 1473-1486 14 p.

Research output: Contribution to journalArticle

Glioblastoma
Cell Differentiation
Genes
Neoplasms
Neoplastic Stem Cells

EGFRvIII and c-Met pathway inhibitors synergize against PTEN-null/EGFRvIII+ glioblastoma xenografts

Lal, B., Goodwin, C. R., Sang, Y., Foss, C. A., Cornet, K., Muzamil, S., Pomper, M. G., Kim, J. & Laterra, J. Jul 1 2009 In : Molecular Cancer Therapeutics. 8, 7, p. 1751-1760 10 p.

Research output: Contribution to journalArticle

Glioblastoma
Heterografts
Neoplasms
Hepatocyte Growth Factor
Receptor Protein-Tyrosine Kinases
Proton Therapy
Temporal Lobe Epilepsy
Skull Base
Wounds and Injuries
Neoplasms

Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme: Clinical article

McGirt, M. J., Than, K. D., Weingart, J. D., Chaichana, K. L., Attenello, F. J., Olivi, A., Laterra, J., Kleinberg, L. R., Grossman, S. A., Brem, H. & Quiñones-Hinojosa, A. Mar 2009 In : Journal of Neurosurgery. 110, 3, p. 583-588 6 p.

Research output: Contribution to journalArticle

Carmustine
Glioblastoma
Morbidity
Radiation
Brain Edema