John D Gottsch

Professor

1984 …2019

Research output per year

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Research Output

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Article
2019
Open Access
2018

Comparative transcriptome analysis of hESC- and iPSC-derived corneal endothelial cells

Ali, M., Khan, S. Y., Kabir, F., Gottsch, J. D. & Riazuddin, S. A., Nov 2018, In : Experimental eye research. 176, p. 252-257 6 p.

Research output: Contribution to journalArticle

Generation and proteome profiling of PBMC-originated, iPSC-derived corneal endothelial cells

Ali, M., Khan, S. Y., Vasanth, S., Ahmed, M. R., Chen, R., Na, C. H., Thomson, J. J., Qiu, C., Gottsch, J. D. & Riazuddin, S. A., May 2018, In : Investigative Ophthalmology and Visual Science. 59, 6, p. 2437-2444 8 p.

Research output: Contribution to journalArticle

Identification of a novel TCF4 isoform in the human corneal endothelium

Eghrari, A. O., Vasanth, S., Gapsis, B. C., Bison, H., Jurkunas, U., Amer Riazuddin, S. & Gottsch, J. D., 2018, In : Cornea. 37, 7, p. 899-903 5 p.

Research output: Contribution to journalArticle

2017

Automated Retroillumination Photography Analysis for Objective Assessment of Fuchs Corneal Dystrophy

Eghrari, A. O., Mumtaz, A. A., Garrett, B., Rezaei, M., Akhavan, M. S., Riazuddin, S. A. & Gottsch, J. D., Jan 1 2017, In : Cornea. 36, 1, p. 44-47 4 p.

Research output: Contribution to journalArticle

CTG18.1 expansion in TCF4 among African Americans with fuchs’ corneal dystrophy

Eghrari, A. O., Vahedi, S., Afshari, N. A., Riazuddin, S. A. & Gottsch, J. D., Dec 2017, In : Investigative Ophthalmology and Visual Science. 58, 14, p. 6046-6049 4 p.

Research output: Contribution to journalArticle

CTG18.1 Expansion in TCF4 Increases Likelihood of Transplantation in Fuchs Corneal Dystrophy

Eghrari, A. O., Vasanth, S., Wang, J., Vahedi, F., Riazuddin, S. A. & Gottsch, J. D., Jan 1 2017, In : Cornea. 36, 1, p. 40-43 4 p.

Research output: Contribution to journalArticle

Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy

Afshari, N. A., Igo, R. P., Morris, N. J., Stambolian, D., Sharma, S., Pulagam, V. L., Dunn, S., Stamler, J. F., Truitt, B. J., Rimmler, J., Kuot, A., Croasdale, C. R., Qin, X., Burdon, K. P., Riazuddin, S. A., Mills, R., Klebe, S., Minear, M. A., Zhao, J., Balajonda, E. & 16 others, Rosenwasser, G. O., Baratz, K. H., Mootha, V. V., Patel, S. V., Gregory, S. G., Bailey-Wilson, J. E., Price, M. O., Price, F. W., Craig, J. E., Fingert, J. H., Gottsch, J. D., Aldave, A. J., Klintworth, G. K., Lass, J. H., Li, Y. J. & Iyengar, S. K., Mar 30 2017, In : Nature communications. 8, 14898.

Research output: Contribution to journalArticle

2016

FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1

Khan, S. Y., Vasanth, S., Kabir, F., Gottsch, J. D., Khan, A. O., Chaerkady, R., Lee, M. C. W., Leitch, C. C., Ma, Z., Laux, J., Villasmil, R., Khan, S. N., Riazuddin, S., Akram, J., Cole, R. N., Conover Talbot, C., Pourmand, N., Zaghloul, N. A., Fielding Hejtmancik, J. & Amer Riazuddin, S., Apr 6 2016, In : Nature communications. 7, 10953.

Research output: Contribution to journalArticle

2015

Expansion of CTG18.1 trinucleotide repeat in TCF4 is a potent driver of fuchs’ corneal dystrophy

Vasanth, S., Eghrari, A. O., Gapsis, B. C., Wang, J., Haller, N. F., Stark, W. J., Katsanis, N., Amer Riazuddin, S. & Gottsch, J. D., 2015, In : Investigative Ophthalmology and Visual Science. 56, 8, p. 4531-4536 6 p.

Research output: Contribution to journalArticle

Retroillumination photography analysis enhances clinical definition of severe fuchs corneal dystrophy

Eghrari, A. O., Garrett, B. S., Mumtaz, A. A., Edalati, A. E., Meadows, D. N., McGlumphy, E. J., Iliff, B. W. & Gottsch, J. D., 2015, In : Cornea. 34, 12, p. 1623-1626 4 p.

Research output: Contribution to journalArticle

2013

Mutations in AGBL1 cause dominant late-onset Fuchs corneal dystrophy and alter protein-protein interaction with TCF4

Riazuddin, S. A., Vasanth, S., Katsanis, N. & Gottsch, J. D., Oct 3 2013, In : American journal of human genetics. 93, 4, p. 758-764 7 p.

Research output: Contribution to journalArticle

2012

A single-base substitution in the seed region of miR-184 causes EDICT syndrome

Iliff, B. W., Amer Riazuddin, S. & Gottsch, J. D., Jan 2012, In : Investigative Ophthalmology and Visual Science. 53, 1, p. 348-353 6 p.

Research output: Contribution to journalArticle

Mutations in LOXHD1, a recessive-deafness locus, cause dominant late-onset Fuchs corneal dystrophy

Riazuddin, S. A., Parker, D. S., McGlumphy, E. J., Oh, E. C., Iliff, B. W., Schmedt, T., Jurkunas, U., Schleif, R., Katsanis, N. & Gottsch, J. D., Mar 9 2012, In : American journal of human genetics. 90, 3, p. 533-539 7 p.

Research output: Contribution to journalArticle

Prevalence and severity of fuchs corneal dystrophy in tangier island

Eghrari, A. O., McGlumphy, E. J., Iliff, B. W., Wang, J., Emmert, D., Riazuddin, S. A., Katsanis, N. & Gottsch, J. D., Jun 1 2012, In : American journal of ophthalmology. 153, 6, p. 1067-1072 6 p.

Research output: Contribution to journalArticle

2011

Replication of tcf4 through association and linkage studies in late-onset fuchs endothelial corneal dystrophy

Li, Y. J., Minear, M. A., Rimmler, J., Zhao, B., Balajonda, E., Hauser, M. A., Allingham, R. R., Eghrari, A. O., Riazuddin, S. A., Katsanis, N., Gottsch, J. D., Gregory, S. G., Klintworth, G. K. & Afshari, N. A., 2011, In : PloS one. 6, 4, e18044.

Research output: Contribution to journalArticle

2010

Age-severity relationships in families linked to FCD2 with retroillumination photography

McGlumphy, E. J., Yeo, W. S., Riazuddin, S. A., Al-Saif, A., Wang, J., Eghrari, A. O., Meadows, D. N., Emmert, D. G., Katsanis, N. & Gottsch, J. D., Dec 2010, In : Investigative Ophthalmology and Visual Science. 51, 12, p. 6298-6302 5 p.

Research output: Contribution to journalArticle

Missense Mutations in TCF8 Cause Late-Onset Fuchs Corneal Dystrophy and Interact with FCD4 on Chromosome 9p

Riazuddin, S. A., Zaghloul, N. A., Al-Saif, A., Davey, L., Diplas, B. H., Meadows, D. N., Eghrari, A. O., Minear, M. A., Li, Y. J., Klintworth, G. K., Afshari, N., Gregory, S. G., Gottsch, J. D. & Katsanis, N., Jan 6 2010, In : American journal of human genetics. 86, 1, p. 45-53 9 p.

Research output: Contribution to journalArticle

Missense mutations in the sodium borate cotransporter SLC4A11 cause late-onset Fuchs corneal dystrophya

Riazuddin, S. A., Vithana, E. N., Seet, L. F., Liu, Y., Al-Saif, A., Koh, L. W., Heng, Y. M., Aung, T., Meadows, D. N., Eghrari, A. O., Gottsch, J. D. & Katsanis, N., Nov 2010, In : Human mutation. 31, 11, p. 1261-1268 8 p.

Research output: Contribution to journalArticle

Treatment With Voriconazole in 3 Eyes With Resistant Acanthamoeba Keratitis

Bang, S., Edell, E., Eghrari, A. O. & Gottsch, J. D., Jan 1 2010, In : American journal of ophthalmology. 149, 1, p. 66-69 4 p.

Research output: Contribution to journalArticle

2009

Linkage of a mild late-onset phenotype of fuchs corneal dystrophy to a novel locus at 5q33.1-q35.2

Riazuddin, S. A., Eghrari, A. O., Al-Saif, A., Davey, L., Meadows, D. N., Katsanis, N. & Gottsch, J. D., Dec 2009, In : Investigative Ophthalmology and Visual Science. 50, 12, p. 5667-5671 5 p.

Research output: Contribution to journalArticle

Presoaking Donor Corneas Reduces Graft Detachment Rates in Descemet Stripping Endothelial Keratoplasty

Lee, J. K., Eghrari, A. O., Desai, N. R., Stark, W. J. & Gottsch, J. D., Mar 2009, In : American journal of ophthalmology. 147, 3, p. 439-441.e2

Research output: Contribution to journalArticle

Progression of fuchs corneal dystrophy in a family linked to the FCD1 locus

Meadows, D. N., Eghrari, A. O., Riazuddin, S. A., Emmert, D. G., Katsanis, N. & Gottsch, J. D., Dec 2009, In : Investigative Ophthalmology and Visual Science. 50, 12, p. 5662-5666 5 p.

Research output: Contribution to journalArticle

Secondary angle closure caused by air migrating behind the pupil in descemet stripping endothelial keratoplasty

Lee, J. S., Desai, N. R., Schmidt, G. W., Jun, A. S., Schein, O. D., Stark, W. J., Eghrari, A. O. & Gottsch, J. D., Jul 2009, In : Cornea. 28, 6, p. 652-656 5 p.

Research output: Contribution to journalArticle

2006

A common locus for late-onset Fuchs corneal dystrophy maps to 18q21.2-q21.32

Sundin, O. H., Broman, K. W., Chang, H. H., Vito, E. C. L., Stark, W. J. & Gottsch, J. D., Sep 1 2006, In : Investigative Ophthalmology and Visual Science. 47, 9, p. 3919-3926 8 p.

Research output: Contribution to journalArticle

Analysis and documentation of progression of Fuchs corneal dystrophy with retroillumination photography

Gottsch, J. D., Sundin, O. H., Rencs, E. V., Emmert, D. G., Stark, W. J., Cheng, C. J. & Schmidt, G. W., May 1 2006, In : Cornea. 25, 4, p. 485-489 5 p.

Research output: Contribution to journalArticle

Immunohistochemistry and electron microscopy of early-onset Fuchs corneal dystrophy in three cases with the same L450W COL8A2 mutation

Zhang, C., Bell, W. R., Sundin, O. H., De La Cruz, Z., Stark, W. J., Green, W. R. & Gottsch, J. D., Dec 1 2006, In : Transactions of the American Ophthalmological Society. 104, p. 85-95 11 p.

Research output: Contribution to journalArticle

Linkage of late-onset fuchs corneal dystrophy to a novel locus at 13pTel-13q12.13

Sundin, O. H., Jun, A. S., Broman, K. W., Liu, S. H., Sheehan, S. E., Vito, E. C. L., Stark, W. J. & Gottsch, J. D., Jan 2006, In : Investigative Ophthalmology and Visual Science. 47, 1, p. 140-145 6 p.

Research output: Contribution to journalArticle

2005

A morphologic study of Fuchs dystrophy and bullous keratopathy

Yuen, H. K. L., Rassier, C. E., Jardeleza, M. S. R., Green, W. R., De La Cruz, Z., Stark, W. J. & Gottsch, J. D., Apr 1 2005, In : Cornea. 24, 3, p. 319-327 9 p.

Research output: Contribution to journalArticle

Cataract surgery in patients with Fuchs' corneal dystrophy: Expanding recommendations for cataract surgery without simultaneous keratoplasty

Seitzman, G. D., Gottsch, J. D. & Stark, W. J., Mar 2005, In : Ophthalmology. 112, 3, p. 441-446 6 p.

Research output: Contribution to journalArticle

Fuchs corneal dystrophy: Aberrant collagen distribution in an L450W Mutant of the COL8A2 gene

Gottsch, J. D., Zhang, C., Sundin, O. H., Bell, W. R., Stark, W. J. & Green, W. R., Dec 2005, In : Investigative Ophthalmology and Visual Science. 46, 12, p. 4504-4511 8 p.

Research output: Contribution to journalArticle

Inheritance of a novel COL8A2 mutation defines a distinct early-onset subtype of fuchs corneal dystrophy

Gottsch, J. D., Sundin, O. H., Liu, S. H., Jun, A. S., Broman, K. W., Stark, W. J., Vito, E. C. L., Narang, A. K., Thompson, J. M. & Magovern, M., Jun 1 2005, In : Investigative Ophthalmology and Visual Science. 46, 6, p. 1934-1939 6 p.

Research output: Contribution to journalArticle

Light-induced oxidative stress in choroidal endothelial cells in mice

Wu, T., Handa, J. T. & Gottsch, J. D., Apr 2005, In : Investigative Ophthalmology and Visual Science. 46, 4, p. 1117-1123 7 p.

Research output: Contribution to journalArticle

2004

A randomized trial of topical cyclosporin 0.05% in topical steroid-resistant atopic keratoconjunctivitis

Akpek, E. K., Dart, J. K., Watson, S., Christen, W., Dursun, D., Yoo, S., O'Brien, T. P., Schein, O. D. & Gottsch, J. D., Mar 2004, In : Ophthalmology. 111, 3, p. 476-482 7 p.

Research output: Contribution to journalArticle

2003

Combined phacoemulsification, intraocular lens implantation, and vitrectomy for eyes with coexisting cataract and vitreoretinal pathology

Demetriades, A. M., Gottsch, J. D., Thomsen, R., Azab, A., Stark, W. J., Campochiaro, P. A., De Juan, E. & Haller, J. A., Mar 1 2003, In : American journal of ophthalmology. 135, 3, p. 291-296 6 p.

Research output: Contribution to journalArticle

Gene expression in donor corneal endothelium

Gottsch, J. D., Seitzman, G. D., Margulies, E. H., Bowers, A. L., Michels, A. J., Saha, S., Jun, A. S., Stark, W. J. & Liu, S. H., Feb 1 2003, In : Archives of ophthalmology. 121, 2, p. 252-258 7 p.

Research output: Contribution to journalArticle

Open Access

Immune of defense at the ocular surface

Akpek, E. K. & Gottsch, J. D., Nov 2003, In : Eye. 17, 8, p. 949-956 8 p.

Research output: Contribution to journalArticle

Serial analysis of gene expression in the corneal endothelium of Fuchs' dystrophy

Gottsch, J. D., Bowers, A. L., Margulies, E. H., Seitzman, G. D., Kim, S. W., Saba, S., Jun, A. S., Stark, W. J. & Liu, S. H., Feb 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 2, p. 594-599 6 p.

Research output: Contribution to journalArticle

Surgical management of anterior chamber epithelial cysts

Haller, J. A., Stark, W. J., Azab, A., Thomsen, R. W. & Gottsch, J. D., Mar 1 2003, In : American journal of ophthalmology. 135, 3, p. 309-313 5 p.

Research output: Contribution to journalArticle

2002

Clinical and ultrastructural features of a novel hereditary anterior segment dysgenesis

Karamursel Akpek, E., Jun, A. S., Goodman, D. F., Green, W. R. & Gottsch, J. D., Mar 11 2002, In : Ophthalmology. 109, 3, p. 513-519 7 p.

Research output: Contribution to journalArticle

Endothelial dystrophy, iris hypoplasia, congenital cataract, and stromal thinning (EDICT) syndrome maps to chromosome 15q22.1-q25.3

Jun, A. S., Broman, K. W., Do, D. V., Akpek, E. K., Stark, W. J. & Gottsch, J. D., Aug 12 2002, In : American journal of ophthalmology. 134, 2, p. 172-176 5 p.

Research output: Contribution to journalArticle

Identification of paramyosin as a binding protein for calgranulin C in experimental helminthic keratitis

Akpek, E. K., Liu, S. H., Thompson, R. & Gottsch, J. D., Aug 5 2002, In : Investigative Ophthalmology and Visual Science. 43, 8, p. 2677-2684 8 p.

Research output: Contribution to journalArticle

2001

EMAP cytokine expression in developing retinas of normal and retinal degeneration (rd) mutant mice

Liu, S. H., Gottsch, J. D., Vinores, S. A., Derevjanik, N. L., McLeod, D. S. & Lutty, G. A., Mar 1 2001, In : Journal of Neuroimmunology. 114, 1-2, p. 28-34 7 p.

Research output: Contribution to journalArticle

Microarray analysis of gene expression in human donor corneas

Jun, A. S., Liu, S. H., Koo, E. H., Do, D. V., Stark, W. J. & Gottsch, J. D., Jan 1 2001, In : Archives of ophthalmology. 119, 11, p. 1629-1634 6 p.

Research output: Contribution to journalArticle

Open Access

Spontaneous corneal perforation in a patient with unusual unilateral pellucid marginal degeneration

Akpek, E. K., Altan-Yaycioglu, R., Gottsch, J. D. & Stark, W. J., Nov 12 2001, In : Journal of cataract and refractive surgery. 27, 10, p. 1698-1700 3 p.

Research output: Contribution to journalArticle

2000

Bilateral consecutive central corneal perforations associated with hypogammaglobulinemia

Akpek, E. K., Haddad, R. S., Winkelstein, J. A. & Gottsch, J. D., Jan 1 2000, In : Ophthalmology. 107, 1, p. 123-126 4 p.

Research output: Contribution to journalArticle