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Jiou Wang

ASSOCIATE PROFESSOR

19972018
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Amyotrophic Lateral Sclerosis Medicine & Life Sciences
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Proteins Medicine & Life Sciences
Caenorhabditis elegans Medicine & Life Sciences

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Research Output 1997 2018

Autophagy as a common pathway in amyotrophic lateral sclerosis

Nguyen, D. K. H., Thombre, R. & Wang, J., Jan 1 2018, (Accepted/In press) In : Neuroscience Letters.

Research output: Contribution to journal › Article

Autophagy
Amyotrophic Lateral Sclerosis
Neurodegenerative Diseases
Frontotemporal Dementia
Motor Neuron Disease

A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism

Swinnen, B., Bento-Abreu, A., Gendron, T. F., Boeynaems, S., Bogaert, E., Nuyts, R., Timmers, M., Scheveneels, W., Hersmus, N., Wang, J., Mizielinska, S., Isaacs, A. M., Petrucelli, L., Lemmens, R., Van Damme, P., Van Den Bosch, L. & Robberecht, W., Mar 1 2018, In : Acta Neuropathologica. 135, 3, p. 427-443 17 p.

Research output: Contribution to journal › Article

Amyotrophic Lateral Sclerosis
Zebrafish
Dipeptides
RNA
Arginine

FUS Regulates Activity of MicroRNA-Mediated Gene Silencing

Zhang, T. , Wu, Y. C. , Mullane, P. , Ji, Y. J. , Liu, H. , He, L. , Arora, A. , Hwang, H. Y. , Alessi, A. F. , Niaki, A. G. , Periz, G. , Guo, L. , Wang, H. , Elkayam, E. , Joshua-Tor, L. , Myong, S. , Kim, J. K. , Shorter, J. , Ong, S. E. , Leung, A. K. L. & 1 others Wang, J., Mar 1 2018, In : Molecular Cell. 69, 5, p. 802-819.e1

Research output: Contribution to journal › Article

Gene Silencing
MicroRNAs
Sarcoma
RNA
RNA-Binding Proteins

Cell-Type specific differences in promoter activity of the ALS-linked C9orf72 mouse ortholog

Langseth, A. J., Kim, J., Ugolino, J. E., Shah, Y., Hwang, H. Y., Wang, J., Bergles, D. E. & Brown, S. P., Dec 1 2017, In : Scientific Reports. 7, 1, 5685

Research output: Contribution to journal › Article

Amyotrophic Lateral Sclerosis
Oligodendroglia
Neurons
Neuroglia
Microglia

Effect of mutation mechanisms on variant composition and distribution in Caenorhabditis elegans

Hwang, H. Y. & Wang, J. Jan 1 2017 In : PLoS Computational Biology. 13, 1, e1005369

Research output: Contribution to journal › Article

Caenorhabditis elegans
mutation
Mutation
Recombination
Genetic Recombination