Research output per year
Research output per year
- 29 results
Search results
-
2023
Dimerization and autophosphorylation of the MST family of kinases are controlled by the same set of residues
Weingartner, K. A., Tran, T., Tripp, K. W. & Kavran, J. M., Jun 2023, In: Biochemical Journal. 480, 15, p. 1165-1182 18 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Phase separation of Hippo signalling complexes
Bonello, T. T., Cai, D., Fletcher, G. C., Wiengartner, K., Pengilly, V., Lange, K. S., Liu, Z., Lippincott-Schwartz, J., Kavran, J. M. & Thompson, B. J., Mar 15 2023, In: EMBO Journal. 42, 6, e112863.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural insights into plasmalemma vesicle-associated protein (PLVAP): Implications for vascular endothelial diaphragms and fenestrae
Chang, T. H., Hsieh, F. L., Gu, X., Smallwood, P. M., Kavran, J. M., Gabelli, S. B. & Nathans, J., Apr 4 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 14, e2221103120.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Kinetic Regulation of the Mammalian Sterile 20-like Kinase 2 (MST2)
Koehler, T. J., Tran, T., Weingartner, K. A. & Kavran, J. M., Aug 16 2022, In: Biochemistry. 61, 16, p. 1683-1693 11 p.Research output: Contribution to journal › Article › peer-review
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2021
The minimal structure for iodotyrosine deiodinase function is defined by an outlier protein from the thermophilic bacterium Thermotoga neapolitana
Sun, Z., Xu, B., Spisak, S., Kavran, J. M. & Rokita, S. E., Dec 1 2021, In: Journal of Biological Chemistry. 297, 6, 101385.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Biophysical characterization of SARAH domain-mediated multimerization of Hippo pathway complexes in Drosophila
Cairns, L., Patterson, A., Weingartner, K. A., Koehler, T. J., Deangelis, D. R., Tripp, K. W., Bothner, B. & Kavran, J. M., May 1 2020, In: Journal of Biological Chemistry. 295, 18, p. 6202-6213 12 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Increasing kinase domain proximity promotes MST2 autophosphorylation during hippo signaling
Tran, T., Mitra, J., Ha, T. & Kavran, J. M., Nov 20 2020, In: Journal of Biological Chemistry. 295, 47, p. 16166-16179 14 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2018
Salvador has an extended SARAH domain that mediates binding to Hippo kinase
Cairns, L., Tran, T., Fowl, B. H., Patterson, A., Kim, Y. J., Bothner, B. & Kavran, J. M., Apr 13 2018, In: Journal of Biological Chemistry. 293, 15, p. 5532-5543 12 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
2017
Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase
Ingavat, N., Kavran, J. M., Sun, Z. & Rokita, S. E., Feb 28 2017, In: Biochemistry. 56, 8, p. 1130-1139 10 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Structural Insights into the Regulation of Hippo Signaling
Cairns, L., Tran, T. & Kavran, J. M., Mar 17 2017, In: ACS chemical biology. 12, 3, p. 601-610 10 p.Research output: Contribution to journal › Review article › peer-review
10 Scopus citations -
2015
46,XY gonadal dysgenesis due to a homozygous mutation in desert hedgehog (DHH) identified by exome sequencing
Werner, R., Merz, H., Birnbaum, W., Marshall, L., Schröder, T., Reiz, B., Kavran, J. M., Bäumer, T., Capetian, P. & Hiort, O., Jul 1 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 7, p. E1022-E1029Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
A Naturally Occurring Repeat Protein with High Internal Sequence Identity Defines a New Class of TPR-like Proteins
Marold, J. D., Kavran, J. M., Bowman, G. D. & Barrick, D., Nov 3 2015, In: Structure. 23, 11, p. 2055-2065 11 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Immunoaffinity Purification of Proteins
Kavran, J. M. & Leahy, D. J., Jun 20 2015, Methods in Enzymology. Academic Press Inc., p. 27-36 10 p. (Methods in Enzymology; vol. 559).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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2014
Coupling antibody to cyanogen bromide-activated sepharose
Kavran, J. M. & Leahy, D. J., 2014, Laboratory Methods in Enzymology: Protein Part C. Academic Press Inc., p. 27-34 8 p. (Methods in Enzymology; vol. 541).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Open Access13 Scopus citations -
How IGF-1 activates its receptor
Kavran, J. M., McCabe, J. M., Byrne, P. O., Connacher, M. K., Wang, Z., Ramek, A., Sarabipour, S., Shan, Y., Shaw, D. E., Hristova, K., Cole, P. A. & Leahy, D. J., Sep 25 2014, In: eLife. 3, e03772.Research output: Contribution to journal › Article › peer-review
Open Access91 Scopus citations -
Lysis of mammalian and Sf9 cells
Kavran, J. M. & Leahy, D. J., 2014, Laboratory Methods in Enzymology: Protein Part A. Academic Press Inc., p. 47-52 6 p. (Methods in Enzymology; vol. 536).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Open Access -
Polyspecific pyrrolysyl-tRNA synthetases from directed evolution
Guo, L. T., Wang, Y. S., Nakamura, A., Eiler, D., Kavran, J. M., Wong, M., Kiessling, L. L., Steitz, T. A., O'Donoghue, P. & Söll, D., Nov 25 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 47, p. 16724-16729 6 p.Research output: Contribution to journal › Article › peer-review
Open Access62 Scopus citations -
Regulation of S-adenosylhomocysteine hydrolase by lysine acetylation
Wang, Y., Kavran, J. M., Chen, Z., Karukurichi, K. R., Leahy, D. J. & Cole, P. A., Nov 7 2014, In: Journal of Biological Chemistry. 289, 45, p. 31361-31372 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access19 Scopus citations -
Silver staining of SDS-polyacrylamide gel
Kavran, J. M. & Leahy, D. J., 2014, Laboratory Methods in Enzymology: Protein Part C. Academic Press Inc., p. 169-176 8 p. (Methods in Enzymology; vol. 541).Research output: Chapter in Book/Report/Conference proceeding › Chapter
7 Scopus citations -
Single cell cloning of a stable mammalian cell line
Longo, P. A., Kavran, J. M., Kim, M. S. & Leahy, D. J., Jan 1 2014, Laboratory Methods in Enzymology: Protein Part A. Academic Press Inc., p. 165-172 8 p. (Methods in Enzymology; vol. 536).Research output: Chapter in Book/Report/Conference proceeding › Chapter
6 Scopus citations -
2013
Generating mammalian stable cell lines by electroporation
A. Longo, P., Kavran, J. M., Kim, M. S. & Leahy, D. J., 2013, Laboratory Methods in Enzymology: DNa. Academic Press Inc., p. 209-226 18 p. (Methods in Enzymology; vol. 529).Research output: Chapter in Book/Report/Conference proceeding › Chapter
8 Scopus citations -
Transient mammalian cell transfection with polyethylenimine (PEI)
Longo, P. A., Kavran, J. M., Kim, M. S. & Leahy, D. J., 2013, Laboratory Methods in Enzymology: DNa. Academic Press Inc., p. 227-240 14 p. (Methods in Enzymology; vol. 529).Research output: Chapter in Book/Report/Conference proceeding › Chapter
202 Scopus citations -
2010
All mammalian hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner
Kavran, J. M., Ward, M. D., Oladosu, O. O., Mulepati, S. & Leahy, D. J., Aug 6 2010, In: Journal of Biological Chemistry. 285, 32, p. 24584-24590 7 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
2009
In vitro enzymatic characterization of near full length EGFR in activated and inhibited states
Qiu, C., Tarrant, M. K., Boronina, T., Longo, P. A., Kavran, J. M., Cole, R. N., Cole, P. A. & Leahy, D. J., Jul 21 2009, In: Biochemistry. 48, 28, p. 6624-6632 9 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
2007
Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation
Kavran, J. M., Gundllapalli, S., O'Donoghue, P., Englert, M., Söll, D. & Steitz, T. A., Jul 3 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 27, p. 11268-11273 6 p.Research output: Contribution to journal › Article › peer-review
Open Access136 Scopus citations -
Structure of the Base of the L7/L12 Stalk of the Haloarcula marismortui Large Ribosomal Subunit: Analysis of L11 Movements
Kavran, J. M. & Steitz, T. A., Aug 24 2007, In: Journal of molecular biology. 371, 4, p. 1047-1059 13 p.Research output: Contribution to journal › Article › peer-review
40 Scopus citations -
2000
Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
Ferguson, K. M., Kavran, J. M., Sankaran, V. G., Fournier, E., Isakoff, S. J., Skolnik, E. Y. & Lemmon, M. A., 2000, In: Molecular cell. 6, 2, p. 373-384 12 p.Research output: Contribution to journal › Article › peer-review
Open Access285 Scopus citations -
1998
Phosphatidylinositol-4,5-bisphosphate is required for endocytic coated vesicle formation
Jost, M., Simpson, F., Kavran, J. M., Lemmon, M. A. & Schmid, S. L., Dec 31 1998, In: Current Biology. 8, 25, p. 1399-1404 6 p.Research output: Contribution to journal › Article › peer-review
Open Access191 Scopus citations -
Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains
Kavran, J. M., Klein, D. E., Lee, A., Falasca, M., Isakoff, S. J., Skolnik, E. Y. & Lemmon, M. A., Nov 13 1998, In: Journal of Biological Chemistry. 273, 46, p. 30497-30508 12 p.Research output: Contribution to journal › Article › peer-review
Open Access365 Scopus citations