Jeffrey Rubens

Assistant Professor

20032019
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Fingerprint Dive into the research topics where Jeffrey Rubens is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Pediatrics Medicine & Life Sciences
Glioma Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Diazooxonorleucine Medicine & Life Sciences
Indoleamine-Pyrrole 2,3,-Dioxygenase Medicine & Life Sciences
Carboplatin Medicine & Life Sciences
Methylation Chemical Compounds
Cell Nucleus Active Transport Medicine & Life Sciences

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Research Output 2003 2019

Inhibition of mTORC1 in pediatric low-grade glioma depletes glutathione and therapeutically synergizes with carboplatin

Poore, B., Yuan, M., Arnold, A., Price, A., Alt, J., Rubens, J., Slusher, B., Eberhart, C. G. & Raabe, E., Feb 14 2019, In : Neuro-oncology. 21, 2, p. 252-263 12 p.

Research output: Contribution to journalArticle

Carboplatin
Glioma
Glutathione
Pediatrics
Cell Death

Unbiased metabolic profiling predicts sensitivity of high MYC-expressing atypical teratoid/ rhabdoid tumors to glutamine inhibition with 6-diazo-5-oxo-L-norleucine

Wang, S. Z., Poore, B., Alt, J., Price, A., Allen, S. J., Hanaford, A. R., Kaur, H., Orr, B. A., Slusher, B., Eberhart, C. G., Raabe, E. & Rubens, J., Oct 1 2019, In : Clinical Cancer Research. 25, 19, p. 5925-5936 12 p.

Research output: Contribution to journalArticle

Diazooxonorleucine
Glutamine
Norleucine
Survival
Carboplatin

Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors

Casaos, J., Huq, S., Lott, T., Felder, R., Choi, J., Gorelick, N., Peters, M., Xia, Y., Maxwell, R., Zhao, T., Ji, C., Simon, T., Sesen, J., Scotland, S. J., Kast, R. E., Rubens, J., Raabe, E., Eberhart, C. G., Jackson, E., Brem, H. & 2 others, Tyler, B. M. & Skuli, N., Jan 1 2018, In : Oncotarget. 9, 8, p. 8054-8067 14 p.

Research output: Contribution to journalArticle

Ribavirin
Therapeutics
Growth
Typical Teratoid Rhabdoid Tumor
Atypical Teratoid Tumor

Five pediatric cancers – update on genetic implications

Cooper, S., Rubens, J. & Bodurtha, J. N., Feb 1 2017, In : Current Pediatric Reviews. 13, 1, p. 42-48 7 p.

Research output: Contribution to journalReview article

Pediatrics
Neoplasms
Wilms Tumor
Retinoblastoma
Brain Neoplasms

The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma

Miyahara, H., Yadavilli, S., Natsumeda, M., Rubens, J., Rodgers, L., Kambhampati, M., Taylor, I. C., Kaur, H., Asnaghi, L., Eberhart, C. G., Warren, K. E., Nazarian, J. & Raabe, E., Aug 1 2017, In : Cancer Letters. 400, p. 110-116 7 p.

Research output: Contribution to journalArticle

Glioma
Phosphotransferases
Brain Stem Neoplasms
Apoptosis
Protein Biosynthesis