Jeffrey Keefer

Assistant Professor

1988 …2017
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Fingerprint Dive into the research topics where Jeffrey Keefer is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Fetal Hemoglobin Medicine & Life Sciences
Sickle Cell Anemia Medicine & Life Sciences
Adrenergic Receptors Medicine & Life Sciences
Madin Darby Canine Kidney Cells Medicine & Life Sciences
GTP-Binding Proteins Medicine & Life Sciences
2,2-dimethylbutyric acid Medicine & Life Sciences
Azacitidine Medicine & Life Sciences
Adenosine A1 Receptors Medicine & Life Sciences

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Research Output 1988 2017

Clinical evaluation of combined azacitidine and entinostat on the induction of fetal hemoglobin in patients with acute myeloid leukemias and myelodysplastic syndromes

Press, K. R., Uy, N., Keefer, J., Gore, S. D., Carraway, H. E., Sakoian, S. & Prebet, T., Jul 25 2017, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-3 3 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Myelodysplastic Syndromes
Acute Myeloid Leukemia

Identification of Aptamers That Bind to Sickle Hemoglobin and Inhibit Its Polymerization

Purvis, S. H., Keefer, J., Fortenberry, Y. M., Barron-Casella, E. & Casella, J. F., Dec 1 2017, In : Nucleic Acid Therapeutics. 27, 6, p. 354-364 11 p.

Research output: Contribution to journalArticle

Sickle Hemoglobin
Time delay
Sickle Cell Anemia
SELEX Aptamer Technique

Correction to A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia [The Journal of Experimental Medicine 203, 5, (2006), 1185-1196]

McDevitt, M. A., Xie, J., Ganapathy-Kanniappan, S., Griffith, J., Liu, A., McDonald, C., Thuma, P., Gordeuk, V. R., Metz, C. N., Mitchell, R., Keefer, J., David, J., Leng, L. & Bucala, R., 2015, In : Journal of Experimental Medicine. 212, 5, p. 825 1 p.

Research output: Contribution to journalArticle

Acute chest syndrome is associated with single nucleotide polymorphism-defined beta globin cluster haplotype in children with sickle cell anaemia

Bean, C. J., Boulet, S. L., Yang, G., Payne, A. B., Ghaji, N., Pyle, M. E., Hooper, W. C., Bhatnagar, P., Keefer, J., Barron-Casella, E., Casella, J. F. & Debaun, M. R., Oct 2013, In : British Journal of Haematology. 163, 2, p. 268-276 9 p.

Research output: Contribution to journalArticle

Acute Chest Syndrome
Sickle Cell Anemia

Association between baseline fetal hemoglobin levels and incidence of severe vaso-occlusive pain episodes in children with sickle cell anemia

Bhatnagar, P., Keefer, J., Casella, J. F., Barron-Casella, E., Bean, C. J., Hooper, C. W., Payne, A. B., Arking, D. & Debaun, M. R., Oct 2013, In : Pediatric Blood and Cancer. 60, 10

Research output: Contribution to journalArticle

Fetal Hemoglobin
Sickle Cell Anemia