Jeffrey D Rothstein

Professor

1979 …2020

Research output per year

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Research Output

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Review article
2018

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

Keenan, A. B., Jenkins, S. L., Jagodnik, K. M., Koplev, S., He, E., Torre, D., Wang, Z., Dohlman, A. B., Silverstein, M. C., Lachmann, A., Kuleshov, M. V., Ma'ayan, A., Stathias, V., Terryn, R., Cooper, D., Forlin, M., Koleti, A., Vidovic, D., Chung, C., Schürer, S. C. & 87 others, Vasiliauskas, J., Pilarczyk, M., Shamsaei, B., Fazel, M., Ren, Y., Niu, W., Clark, N. A., White, S., Mahi, N., Zhang, L., Kouril, M., Reichard, J. F., Sivaganesan, S., Medvedovic, M., Meller, J., Koch, R. J., Birtwistle, M. R., Iyengar, R., Sobie, E. A., Azeloglu, E. U., Kaye, J., Osterloh, J., Haston, K., Kalra, J., Finkbiener, S., Li, J., Milani, P., Adam, M., Escalante-Chong, R., Sachs, K., Lenail, A., Ramamoorthy, D., Fraenkel, E., Daigle, G., Hussain, U., Coye, A., Rothstein, J., Sareen, D., Ornelas, L., Banuelos, M., Mandefro, B., Ho, R., Svendsen, C. N., Lim, R. G., Stocksdale, J., Casale, M. S., Thompson, T. G., Wu, J., Thompson, L. M., Dardov, V., Venkatraman, V., Matlock, A., Van Eyk, J. E., Jaffe, J. D., Papanastasiou, M., Subramanian, A., Golub, T. R., Erickson, S. D., Fallahi-Sichani, M., Hafner, M., Gray, N. S., Lin, J. R., Mills, C. E., Muhlich, J. L., Niepel, M., Shamu, C. E., Williams, E. H., Wrobel, D., Sorger, P. K., Heiser, L. M., Gray, J. W., Korkola, J. E., Mills, G. B., LaBarge, M., Feiler, H. S., Dane, M. A., Bucher, E., Nederlof, M., Sudar, D., Gross, S., Kilburn, D. F., Smith, R., Devlin, K., Margolis, R., Derr, L., Lee, A. & Pillai, A., Jan 24 2018, In : Cell Systems. 6, 1, p. 13-24 12 p.

Research output: Contribution to journalReview article

2017

Oligodendroglia: Metabolic supporters of neurons

Philips, T. & Rothstein, J. D., Sep 1 2017, In : Journal of Clinical Investigation. 127, 9, p. 3271-3280 10 p.

Research output: Contribution to journalReview article

2016

The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease

Haeusler, A. R., Donnelly, C. J. & Rothstein, J. D., Jun 1 2016, In : Nature Reviews Neuroscience. 17, 6, p. 383-395 13 p.

Research output: Contribution to journalReview article

2015

ALSUntangled: Introducing the table of evidence

ALSUntangled Group, Mar 1 2015, In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 16, 1-2, p. 142-145 4 p.

Research output: Contribution to journalReview article

2014

Advances in treating amyotrophic lateral sclerosis: Insights from pathophysiological studies

Vucic, S., Rothstein, J. D. & Kiernan, M. C., Aug 2014, In : Trends in neurosciences. 37, 8, p. 433-442 10 p.

Research output: Contribution to journalReview article

Glial cells in amyotrophic lateral sclerosis

Philips, T. & Rothstein, J. D., Dec 1 2014, In : Experimental Neurology. 262, Part B, p. 111-120 10 p.

Research output: Contribution to journalReview article

Mitochondrial abnormalities and low grade inflammation are present in the skeletal muscle of a minority of patients with amyotrophic lateral sclerosis; An observational myopathology study

Al-Sarraj, S., King, A., Cleveland, M., Pradat, P. F., Corse, A., Rothstein, J. D., Leigh, P. N., Abila, B., Bates, S., Wurthner, J. & Meininger, V., Jan 27 2014, In : Acta Neuropathologica Communications. 2, 1, 165.

Research output: Contribution to journalReview article

2013

ALS untangled no. 20: The Deanna protocol

Fournier, C., Bedlack, R., Hardiman, O., Heiman-Patterson, T., Gutmann, L., Bromberg, M., Ostrow, L., Carter, G., Kabashi, E., Bertorini, T., Mozaffar, T., Andersen, P., Dietz, J., Gamez, J., Dimachkie, M., Wang, Y., Wicks, P., Heywood, J., Novella, S., Rowland, L. P. & 69 others, Pioro, E., Kinsley, L., Mitchell, K., Glass, J., Sathornsumetee, S., Kwiecinski, H., Baker, J., Atassi, N., Forshew, D., Ravits, J., Conwit, R., Jackson, C., Sherman, A., Dalton, K., Tindall, K., Gonzalez, G., Robertson, J., Phillips, L., Benatar, M., Sorenson, E., Shoesmith, C., Nash, S., Maragakis, N., Moore, D., Caress, J., Boylan, K., Armon, C., Grosso, M., Gerecke, B., Wymer, J., Oskarsson, B., Bowser, R., Drory, V., Shefner, J., Lechtzin, N., Leitner, M., Miller, R., Mitsumoto, H., Levine, T., Russell, J., Sharma, K., Saperstein, D., McClusky, L., MacGowan, D., Licht, J., Verma, A., Strong, M., Lomen-Hoerth, C., Tandan, R., Rivner, M., Kolb, S., Polak, M., Rudnicki, S., Kittrell, P., Quereshi, M., Sachs, G., Pattee, G., Weiss, M., Kissel, J., Goldstein, J., Rothstein, J., Pastula, D., Levitsky, G., Ogino, M., Rosenfeld, J., Carmi, E., Oster, C., Barkhaus, P. & Valor, E., May 1 2013, In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 14, 4, p. 319-323 5 p.

Research output: Contribution to journalReview article

Oligodendroglia: Metabolic supporters of axons

Morrison, B. M., Lee, Y. & Rothstein, J. D., Dec 1 2013, In : Trends in Cell Biology. 23, 12, p. 644-651 8 p.

Research output: Contribution to journalReview article

The blood-brain barrier: An engineering perspective

Wong, A. D., Ye, M., Levy, A. F., Rothstein, J. D., Bergles, D. E. & Searson, P. C., Aug 30 2013, In : Frontiers in Neuroengineering. JUL

Research output: Contribution to journalReview article

2012

ALS untangled no. 17: "When ALS Is Lyme"

Bedlack, R., Hardiman, O., Heiman-Patterson, T., Gutmann, L., Bromberg, M., Ostrow, L., Carter, G., Kabashi, E., Bertorini, T., Mozaffar, T., Andersen, P., Dietz, J., Gamez, J., Dimachkie, M., Wang, Y., Wicks, P., Heywood, J., Novella, S., Rowland, L. P., Pioro, E. & 61 others, Kinsley, L., Mitchell, K., Glass, J., Sathornsumetee, S., Kwiecinski, H., Baker, J., Atassi, N., Forshew, D., Ravits, J., Conwit, R., Jackson, C., Sherman, A., Dalton, K., Tindall, K., Gonzalez, G., Robertson, J., Phillips, L., Benatar, M., Sorenson, E., Shoesmith, C., Nash, S., Marigakis, N., Moore, D., Caress, J., Boylan, K., Armon, C., Grosso, M., Gerecke, B., Wymer, J., Oskarsson, B., Bowser, R., Drory, V., Shefner, J., Lechtzin, N., Leitner, M., Miller, R., Mitsumoto, H., Levine, T., Russell, J., Sharma, K., Saperstein, D., McClusky, L., MacGowan, D., Licht, J., Verma, A., Strong, M., Lomen-Hoerth, C., Tandan, R., Rivner, M., Kolb, S., Polak, M., Rudnicki, S., Kittrell, P., Quereshi, M., Sachs, G., Pattee, G., Weiss, M., Kissel, J., Goldstein, J., Rothstein, J. & Pastula, D., Sep 1 2012, In : Amyotrophic Lateral Sclerosis. 13, 5, p. 487-491 5 p.

Research output: Contribution to journalReview article

2009

Current hypotheses for the underlying biology of amyotrophic lateral sclerosis

Rothstein, J. D., Jan 1 2009, In : Annals of neurology. 65, SUPPL. 1, p. S3-S9

Research output: Contribution to journalReview article

2006

Mechanisms of Disease: Astrocytes in neurodegenerative disease

Maragakis, N. J. & Rothstein, J. D., Dec 1 2006, In : Nature Clinical Practice Neurology. 2, 12, p. 679-689 11 p.

Research output: Contribution to journalReview article

2004

Glutamate transporters: Animal models to neurologic disease

Maragakis, N. J. & Rothstein, J. D., Apr 1 2004, In : Neurobiology of Disease. 15, 3, p. 461-473 13 p.

Research output: Contribution to journalReview article

Preclinical studies: How much can we rely on?

Rothstein, J. D., Sep 1 2004, In : Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders. 5, SUPPL. 1, p. 22-25 4 p.

Research output: Contribution to journalReview article

2003

Topiramate protects against motor neuron degeneration in organotypic spinal cord cultures but not in G93A SOD1 transgenic mice

Maragakis, N. J., Jackson, M., Ganel, R. & Rothstein, J. D., Feb 27 2003, In : Neuroscience Letters. 338, 2, p. 107-110 4 p.

Research output: Contribution to journalReview article

2002

Models of amyotrophic lateral sclerosis.

Jackson, M., Ganel, R. & Rothstein, J. D., Nov 2002, In : Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.]. Chapter 9, p. Unit 9.13

Research output: Contribution to journalReview article

Therapeutic developments in the treatment of amyotrophic lateral sclerosis

Jackson, M., Lladó, J. & Rothstein, J. D., Oct 1 2002, In : Expert Opinion on Investigational Drugs. 11, 10, p. 1343-1364 22 p.

Research output: Contribution to journalReview article

2001

Glutamate transporters in neurologic disease

Maragakis, N. J. & Rothstein, J. D., Jan 1 2001, In : Archives of neurology. 58, 3, p. 365-370 6 p.

Research output: Contribution to journalReview article

Open Access
1996

Excitotoxicity hypothesis

Rothstein, J. D., Oct 1 1996, In : Neurology. 47, 4 SUPPL., p. S19-S26

Research output: Contribution to journalReview article

1995

Amyotrophic lateral sclerosis. An autoimmune disease?

Drachman, D. B., Fishman, P. S., Rothstein, J. D., Motomura, M., Lang, B., Vincent, A. & Mellits, E. D., 1995, In : Advances in neurology. 68, p. 59-65 7 p.

Research output: Contribution to journalReview article

Excitotoxic mechanisms in the pathogenesis of amyotrophic lateral sclerosis.

Rothstein, J. D., 1995, In : Advances in neurology. 68, p. 7-20; discussion 21-27

Research output: Contribution to journalReview article

1989

Neurologic manifestations of hepatic disease

Rothstein, J. D. & Herlong, H. F., Jan 1 1989, In : Neurologic clinics. 7, 3, p. 563-578 16 p.

Research output: Contribution to journalReview article