Research Output 1998 2017

2017

Frailty and circulating markers of inflammation in HIV+ and HIV2 men in the multicenter AIDS cohort study

Margolick, J. B., Bream, J. H., Martínez-Maza, O., Lopez, J., Li, X., Phair, J. P., Koletar, S. L. & Jacobson, L. P. Apr 1 2017 In : Journal of Acquired Immune Deficiency Syndromes. 74, 4, p. 407-417 11 p.

Research output: Contribution to journalArticle

Cohort Studies
HIV
Inflammation
C-Reactive Protein
Comorbidity

Multiplex assay reliability and long-term intra-individual variation of serologic inflammatory biomarkers

McKay, H. S., Margolick, J. B., Martínez-Maza, O., Lopez, J., Phair, J., Rappocciolo, G., Denny, T. N., Magpantay, L. I., Jacobson, L. P. & Bream, J. H. Feb 1 2017 In : Cytokine. 90, p. 185-192 8 p.

Research output: Contribution to journalArticle

Biological Markers
Biomarkers
Cytokines
Beryllium
Cytokine Receptors
2016

Association of serum cytokines with oral HPV clearance

Lam, J. O., Bream, J. H., Sugar, E. A., Coles, C. L., Weber, K. M., Burk, R. D., Wiley, D. J., Cranston, R. D., Reddy, S., Margolick, J. B., Strickler, H. D., Wentz, A., Jacobson, L., Guo, Y., Xiao, W., Gillison, M. L. & D'Souza, G. Jul 1 2016 In : Cytokine. 83, p. 85-91 7 p.

Research output: Contribution to journalArticle

Cytokines
Serum
Hazards
Papillomavirus Infections
Tumor Necrosis Factor-alpha

Evaluation of the safety, tolerability, and immunogenicity of an oral, inactivated whole-cell shigella flexneri 2a vaccine in healthy adult subjects

Chakraborty, S., Harro, C., DeNearing, B., Bream, J., Bauers, N., Dally, L., Flores, J., Van De Verg, L., Sack, D. A. & Walker, R. Apr 1 2016 In : Clinical and Vaccine Immunology. 23, 4, p. 315-325 11 p.

Research output: Contribution to journalArticle

Shigella flexneri
Healthy Volunteers
Vaccines
Safety
Serum

Host factors associated with serologic inflammatory markers assessed using multiplex assays

McKay, H. S., Bream, J. H., Margolick, J. B., Martínez-Maza, O., Phair, J. P., Rinaldo, C. R., Abraham, A. G. & Jacobson, L. P. Sep 1 2016 In : Cytokine. 85, p. 71-79 9 p.

Research output: Contribution to journalArticle

Biological Markers
Biomarkers
Inflammation
Beryllium
Cytokine Receptor gp130

Inflammatory Biomarkers and Mortality Risk among HIV-Suppressed Men: A Multisite Prospective Cohort Study

Wada, N. I., Bream, J. H., Martínez-Maza, O., Macatangay, B., Galvin, S. R., Margolick, J. B. & Jacobson, L. P. Oct 1 2016 In : Clinical Infectious Diseases. 63, 7, p. 984-990 7 p.

Research output: Contribution to journalArticle

Cohort Studies
Biological Markers
HIV
Prospective Studies
Mortality

Longitudinal Changes over 10 Years in Free Testosterone among HIV-Infected and HIV-Uninfected Men

Slama, L. , Jacobson, L. P. , Li, X. , Palella, F. J. , Margolick, J. B. , Kingsley, L. A. , Wiley, D. J. , Pialoux, G. , Dobs, A. S. , Brown, T. T. , Bream, J. , Crain, B. , Elion, R. , Estrella, M. , Johnson-Hill, L. , Leng, S. , Monroe, A. , Munro, C. , Plankey, M. W. , Post, W. & 52 others Sacktor, N., Schrack, J., Thio, C., Wolinsky, S. M., Phair, J. P., Badri, S., Gabuzda, D., Penugonda, S., Reddy, S., Stephens, M., Teplin, L., Detels, R., Martínez-Maza, O., Aronow, A., Anton, P., Bolan, R., Breen, E., Butch, A., Hussain, S., Jamieson, B., Miller, E. N., Oishi, J., Vinters, H., Witt, M., Yang, O., Young, S., Zhang, Z. F., Rinaldo, C. R., Becker, J. T., Gupta, P., Ho, K., Koletar, S., Martinson, J. J., Mellors, J. W., Silvestre, A. J., Stall, R. D., D'Souza, G., Alison, Abraham, Althoff, K., Deal, J., Duggal, P., Haberlen, S., Muoz, A., Ng, D., Schollenberger, J., Seaberg, E. C., Su, S., Surkan, P., Huebner, R. E., Dominguez, G. & for the Multicenter AIDS Cohort Study (MACS) Jan 1 2016 In : Journal of Acquired Immune Deficiency Syndromes. 71, 1, p. 57-64 8 p.

Research output: Contribution to journalArticle

Testosterone
HIV
Confidence Intervals
Cohort Studies
Highly Active Antiretroviral Therapy

MicroRNA-related polymorphisms and non-Hodgkin lymphoma susceptibility in the Multicenter AIDS Cohort Study

Peckham-Gregory, E. C., Thapa, D. R., Martinson, J., Duggal, P., Penugonda, S., Bream, J. H., Chang, P. Y., Dandekar, S., Chang, S. C., Detels, R., Martínez-Maza, O., Zhang, Z. F. & Hussain, S. K. Dec 1 2016 In : Cancer Epidemiology. 45, p. 47-57 11 p.

Research output: Contribution to journalArticle

MicroRNAs
Non-Hodgkin's Lymphoma
Cohort Studies
AIDS-Related Lymphoma
Odds Ratio

Plasma tryptophan and the kynurenine-tryptophan ratio are associated with the acquisition of statural growth deficits and oral vaccine underperformance in populations with environmental enteropathy

Kosek, M. N., Mduma, E., Kosek, P. S., Lee, G. O., Svensen, E., Pan, W. K. Y., Olortegui, M. P., Bream, J. H., Patil, C., Asayag, C. R., Sanchez, G. M., Caulfield, L. E., Gratz, J. & Yori, P. P. Oct 1 2016 In : American Journal of Tropical Medicine and Hygiene. 95, 4, p. 928-937 10 p.

Research output: Contribution to journalArticle

Kynurenine
Tryptophan
Vaccines
Indoleamine-Pyrrole 2,3,-Dioxygenase
Peru

The association of medication use with clearance or persistence of oral HPV infection

Lam, J. O., Sugar, E. A., Cranston, R. D., Weber, K. M., Burk, R. D., Wiley, D. J., Reddy, S., Margolick, J. B., Strickler, H. D., Wentz, A., Jacobson, L., Coles, C. L., Bream, J. H., Rositch, A. F., Guo, Y., Xiao, W., Gillison, M. L. & D’Souza, G. Dec 1 2016 In : Cancer Causes and Control. 27, 12, p. 1491-1498 8 p.

Research output: Contribution to journalArticle

Papillomavirus Infections
HIV
Antipsychotic Agents
Anti-Anxiety Agents
Hypnotics and Sedatives
2015

Accelerated longitudinal gait speed decline in HIV-infected older men

Schrack, J. A. , Althoff, K. N. , Jacobson, L. P. , Erlandson, K. M. , Jamieson, B. D. , Koletar, S. L. , Phair, J. , Ferrucci, L. , Brown, T. T. , Margolick, J. B. , Bream, J. H. , Crain, B. , Dobs, A. , Johnson-Hill, L. , Leng, S. , Munro, C. , Plankey, M. W. , Post, W. , Sacktor, N. , Thio, C. & 40 others Wolinsky, S. M., Phair, J. P., Badri, S., O'Gorman, M., Ostrow, D., Palella, F., Ragin, A., Detels, R., Martínez-Maza, O., Aronow, A., Bolan, R., Breen, E., Butch, A., Miller, E. N., Oishi, J., Vinters, H., Wiley, D., Witt, M., Yang, O., Young, S., Zhang, Z. F., Rinaldo, C. R., Kingsley, L. A., Becker, J. T., Cranston, R. D., Martinson, J. J., Mellors, J. W., Silvestre, A. J., Stall, R. D., Munoz, A., Abraham, A., Cox, C., Deal, J., D'Souza, G., Duggal, P., Schollenberger, J., Seaberg, E. C., Su, S., Surkan, P. & for the Multicenter AIDS Cohort Study Dec 1 2015 In : Journal of Acquired Immune Deficiency Syndromes. 70, 4, p. 370-376 7 p.

Research output: Contribution to journalArticle

Gait
HIV
Cohort Studies
Biological Markers
Confidence Intervals

Lipid levels in HIV-positive men receiving anti-retroviral therapy are not associated with copy number variation of reverse cholesterol transport pathway genes Genetics

Marino, R. B., Kingsley, L. A., Hussain, S. K., Bream, J. H., Penogonda, S., Duggal, P. & Martinson, J. J. Nov 21 2015 In : BMC Research Notes. 8, 1, 697

Research output: Contribution to journalArticle

Cholesterol
HIV
Lipids
Genes
Cyclic AMP Receptor Protein

The effect of HAART-induced HIV suppression on circulating markers of inflammation and immune activation

Wada, N. I., Jacobson, L. P., Margolick, J. B., Breen, E. C., Macatangay, B., Penugonda, S., Martínez-Maza, O. & Bream, J. H. Feb 20 2015 In : AIDS. 29, 4, p. 463-471 9 p.

Research output: Contribution to journalArticle

Highly Active Antiretroviral Therapy
Biological Markers
HIV
Inflammation
Cohort Studies
2014

17β-Estradiol protects females against influenza by recruiting neutrophils and increasing virus-specific CD8 T cell responses in the lungs

Robinson, D. P., Hall, O. J., Nilles, T. L., Bream, J. H. & Klein, S. L. 2014 In : Journal of Virology. 88, 9, p. 4711-4720 10 p.

Research output: Contribution to journalArticle

Human Influenza
Estradiol
Neutrophils
Viruses
T-Lymphocytes

A peripheral circulating TH1 cytokine profile is inversely associated with prostate cancer risk in CLUE II

Bhavsar, N. A., Bream, J. H., Meeker, A. K., Drake, C. G., Peskoe, S. B., Dabitao, D., De Marzo, A. M., Isaacs, W. B. & Platz, E. A. Nov 1 2014 In : Cancer Epidemiology Biomarkers and Prevention. 23, 11, p. 2561-2567 7 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Confidence Intervals
Cytokines
Interleukin-6
Interleukin-8

Circulating mediators of inflammation and immune activation in AIDS-related non-Hodgkin lymphoma

Nolen, B. M., Breen, E. C., Bream, J. H., Jenkins, F. J., Kingsley, L. A., Rinaldo, C. R. & Lokshin, A. E. Jun 12 2014 In : PLoS One. 9, 6, e99144

Research output: Contribution to journalArticle

AIDS-Related Lymphoma
Inflammation Mediators
Non-Hodgkin's Lymphoma
Biological Markers
HIV

Distinct assembly profiles of HLA-B molecules syed monem rizvi1

Salam, N., Geng, J., Qi, Y., Bream, J. H., Duggal, P., Hussain, S. K., Martinson, J., Wolinsky, S. M., Carrington, M. & Raghavan, M. Jun 1 2014 In : Journal of Immunology. 192, 11, p. 4967-4976 10 p.

Research output: Contribution to journalArticle

HLA-B Antigens
Peptides
Communicable Diseases
Genes
HLA-C Antigens

Heterogeneity of CD4+ and CD8+ T-cell responses to cytomegalovirus in HIV-infected and HIV-uninfected men who have sex with men

Li, H., Margolick, J. B., Bream, J. H., Nilles, T. L., Langan, S., Bui, H. T., Sylwester, A. W., Picker, L. J. & Leng, S. X. Aug 1 2014 In : Journal of Infectious Diseases. 210, 3, p. 400-404 5 p.

Research output: Contribution to journalArticle

Cytomegalovirus
HIV
T-Lymphocytes
Antigens
Open Reading Frames

LILRB2 Interaction with HLA Class I Correlates with Control of HIV-1 Infection

Bashirova, A. A. , Martin-Gayo, E. , Jones, D. C. , Qi, Y. , Apps, R. , Gao, X. , Burke, P. S. , Taylor, C. J. , Rogich, J. , Wolinsky, S. , Bream, J. H. , Duggal, P. , Hussain, S. , Martinson, J. , Weintrob, A. , Kirk, G. D. , Fellay, J. , Buchbinder, S. P. , Goedert, J. J. , Deeks, S. G. & 8 others Pereyra, F., Trowsdale, J., Lichterfeld, M., Telenti, A., Walker, B. D., Allen, R. L., Carrington, M. & Yu, X. G. 2014 In : PLoS Genetics. 10, 3, e1004196

Research output: Contribution to journalArticle

HLA Antigens
HIV-1
Infection
leukocytes
antigen

MAPKAP kinase 3 suppresses Ifng gene expression and attenuates NK cell cytotoxicity and Th1 CD4 T-cell development upon influenza A virus infection

Köther, K., Nordhoff, C., Masemann, D., Varga, G., Bream, J. H., Gaestel, M., Wixler, V. & Ludwig, S. Oct 1 2014 In : FASEB Journal. 28, 10, p. 4235-4246 12 p.

Research output: Contribution to journalArticle

Influenza A virus
Natural Killer Cells
Phosphotransferases
T-Lymphocytes
Gene Expression

Serum levels of cytokines and biomarkers for inflammation and immune activation, and HIV-Associated non-hodgkin B-Cell lymphoma risk

Vendrame, E., Hussain, S. K., Breen, E. C., Magpantay, L. I., Widney, D. P., Jacobson, L. P., Variakojis, D., Knowlton, E. R., Bream, J. H., Ambinder, R. F., Detels, R. & Mart́nez-Maza, O. Feb 2014 In : Cancer Epidemiology Biomarkers and Prevention. 23, 2, p. 343-349 7 p.

Research output: Contribution to journalArticle

B-Cell Lymphoma
Non-Hodgkin's Lymphoma
Biological Markers
HIV
Cytokines

Serum MicroRNAs in HIV-infected individuals as pre-diagnosis biomarkers for AIDS-NHL

Thapa, D. R., Hussain, S. K., Tran, W. C., D'souza, G., Bream, J. H., Achenback, C. J., Ayyavoo, V., Detels, R. & Martínez-Maza, O. Jun 1 2014 In : Journal of Acquired Immune Deficiency Syndromes. 66, 2, p. 229-237 9 p.

Research output: Contribution to journalArticle

AIDS-Related Lymphoma
MicroRNAs
Non-Hodgkin's Lymphoma
Biological Markers
HIV
2013

A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A

Lane, J. , Mclaren, P. J. , Dorrell, L. , Shianna, K. V. , Stemke, A. , Pelak, K. , Moore, S. , Oldenburg, J. , Alvarez-Roman, M. T. , Angelillo-Scherrer, A. , Boehlen, F. , Bolton-Maggs, P. H. B. , Brand, B. , Brown, D. , Chiang, E. , Cid-Haro, A. R. , Clotet, B. , Collins, P. , Colombo, S. , Dalmau, J. & 37 others Fogarty, P., Giangrande, P., Gringeri, A., Iyer, R., Katsarou, O., Kempton, C., Kuriakose, P., Lin, J., Makris, M., Manco-Johnson, M., Tsakiris, D. A., Martinez-Picado, J., Mauser-Bunschoten, E., Neff, A., Oka, S., Oyesiku, L., Parra, R., Peter-Salonen, K., Powell, J., Recht, M., Shapiro, A., Stine, K., Talks, K., Telenti, A., Wilde, J., Yee, T. T., Wolinsky, S. M., Martinson, J., Hussain, S. K., Bream, J. H., Jacobson, L. P., Carrington, M., Goedert, J. J., Haynes, B. F., Mcmichael, A. J., Goldstein, D. B. & Fellay, J. May 2013 In : Human Molecular Genetics. 22, 9, p. 1903-1910 8 p., ddt033

Research output: Contribution to journalArticle

Genome-Wide Association Study
Hemophilia A
HIV Infections
Single Nucleotide Polymorphism
HIV-1

Serum levels of the chemokine CXCL13, genetic variation in CXCL13 and its receptor CXCR5, and HIV-associated non-Hodgkin B-cell lymphoma risk

Hussain, S. K., Zhu, W., Chang, S. C., Breen, E. C., Vendrame, E., Magpantay, L., Widney, D., Conn, D., Sehl, M., Jacobson, L. P., Bream, J. H., Wolinsky, S., Rinaldo, C. R., Ambinder, R. F., Detels, R., Zhang, Z. F. & Martínez-Maza, O. Feb 2013 In : Cancer Epidemiology Biomarkers and Prevention. 22, 2, p. 295-307 13 p.

Research output: Contribution to journalArticle

CXCR5 Receptors
Chemokine CXCL13
HIV Receptors
B-Cell Lymphoma
Non-Hodgkin's Lymphoma

Temporal stability of serum concentrations of cytokines and soluble receptors measured across two years in low-risk HIV-seronegative men

Epstein, M. M., Breen, E. C., Magpantay, L., Detels, R., Lepone, L., Penugonda, S., Bream, J. H., Jacobson, L. P., Martínez-Maza, O. & Birmann, B. M. Nov 2013 In : Cancer Epidemiology Biomarkers and Prevention. 22, 11, p. 2009-2015 7 p.

Research output: Contribution to journalArticle

Cytokine Receptors
Biological Markers
HIV
Serum
Chronic Disease
2012

A protective role for human IL-10-expressing CD4 + T cells in colitis

Ranatunga, D. C., Ramakrishnan, A., Uprety, P., Wang, F., Zhang, H., Margolick, J. B., Brayton, C. & Bream, J. H. Aug 1 2012 In : Journal of Immunology. 189, 3, p. 1243-1252 10 p.

Research output: Contribution to journalArticle

Colitis
Interleukin-10
T-Lymphocytes
Histones
Mucous Membrane

B-cell activation induced microRNA-21 is elevated in circulating B cells preceding the diagnosis of AIDS-related non-Hodgkin lymphomas

Thapa, D. R., Bhatia, K., Bream, J. H., D'Souza, G., Rinaldo, C. R., Wolinsky, S., Detels, R. & Martínez-Maza, O. Jun 1 2012 In : AIDS. 26, 9, p. 1177-1180 4 p.

Research output: Contribution to journalArticle

AIDS-Related Lymphoma
MicroRNAs
Non-Hodgkin's Lymphoma
B-Lymphocytes
Immunoglobulin M

Differential serum cytokine responses to inactivated and live attenuated seasonal influenza vaccines

Ramakrishnan, A., Althoff, K. N., Lopez, J. A., Coles, C. L. & Bream, J. H. Dec 2012 In : Cytokine. 60, 3, p. 661-666 6 p.

Research output: Contribution to journalArticle

Attenuated Vaccines
Inactivated Vaccines
Influenza Vaccines
Cytokines
Serum
2011

B-cell stimulatory cytokines and markers of immune activation are elevated several years prior to the diagnosis of systemic AIDS-associated non-Hodgkin B-cell lymphoma

Breen, E. C., Hussain, S. K., Magpantay, L., Jacobson, L. P., Detels, R., Rabkin, C. S., Kaslow, R. A., Variakojis, D., Bream, J. H., Rinaldo, C. R., Ambinder, R. F. & Martinez-Maza, O. Jul 2011 In : Cancer Epidemiology Biomarkers and Prevention. 20, 7, p. 1303-1314 12 p.

Research output: Contribution to journalArticle

B-Cell Lymphoma
Non-Hodgkin's Lymphoma
B-Lymphocytes
Biological Markers
Cytokines

Copy number variation of KIR genes influences HIV-1 control

Pelak, K. , Need, A. C. , Fellay, J. , Shianna, K. V. , Feng, S. , Urban, T. J. , Ge, D. , de Luca, A. , Martinez-Picado, J. , Wolinsky, S. M. , Martinson, J. J. , Jamieson, B. D. , Bream, J. H. , Martin, M. P. , Borrow, P. , Letvin, N. L. , McMichael, A. J. , Haynes, B. F. , Telenti, A. , Carrington, M. & 2 others Goldstein, D. B. & Alter, G. Nov 2011 In : PLoS Biology. 9, 11, e1001208

Research output: Contribution to journalArticle

KIR Receptors
Natural Killer Cells
HIV-1
Genes
Human immunodeficiency virus 1

Effect of highly active antiretroviral therapy on biomarkers of B-lymphocyte activation and inflammation

Regidor, D. L., Detels, R., Breen, E. C., Widney, D. P., Jacobson, L. P., Palella, F., Rinaldo, C. R., Bream, J. H. & Martínez-Maza, O. Jan 28 2011 In : AIDS. 25, 3, p. 303-314 12 p.

Research output: Contribution to journalArticle

Highly Active Antiretroviral Therapy
Lymphocyte Activation
B-Lymphocytes
Biological Markers
Inflammation

Frailty is associated with impairment of vaccine-induced antibody response and increase in post-vaccination influenza infection in community-dwelling older adults

Yao, X., Hamilton, R. G., Weng, N. P., Xue, Q. L., Bream, J. H., Li, H., Tian, J., Yeh, S. H., Resnick, B., Xu, X., Walston, J., Fried, L. P. & Leng, S. X. Jul 12 2011 In : Vaccine. 29, 31, p. 5015-5021 7 p.

Research output: Contribution to journalArticle

Inactivated Vaccines
Human Influenza
Antibody Formation
Vaccination
Vaccines

Genome-wide association study implicates PARD3B-based AIDS restriction

Troyer, J. L. , Nelson, G. W. , Lautenberger, J. A. , Chinn, L. , McIntosh, C. , Johnson, R. C. , Sezgin, E. , Kessing, B. , Malasky, M. , Hendrickson, S. L. , Li, G. , Pontius, J. , Tang, M. , An, P. , Winkler, C. A. , Limou, S. , Le Clerc, S. , Delaneau, O. , Zagury, J. F. , Schuitemaker, H. & 7 others Van Manen, D., Bream, J. H., Gomperts, E. D., Buchbinder, S., Goedert, J. J., Kirk, G. D. & O'Brien, S. J. May 15 2011 In : Journal of Infectious Diseases. 203, 10, p. 1491-1502 12 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Single Nucleotide Polymorphism
HIV
Genes
Haplotypes
Cytokines
Serum
Interleukin-8
Interleukin-10
HIV Infections

Multisite comparison of high-sensitivity multiplex cytokine assays

Breen, E. C., Reynolds, S. M., Cox, C., Jacobson, L. P., Magpantay, L., Mulder, C. B., Dibben, O., Margolick, J. B., Bream, J. H., Sambrano, E., Martínez-Maza, O., Sinclair, E., Borrow, P., Landay, A. L., Rinaldo, C. R. & Norris, P. J. Aug 2011 In : Clinical and Vaccine Immunology. 18, 8, p. 1229-1242 14 p.

Research output: Contribution to journalArticle

Cytokines
Beryllium
Serum
HIV
Callosities

Prevalence of XMRV nucleic acid and antibody in HIV-1-infected men and in men at risk for HIV-1 infection

Spindler, J., Hackett, J., Qiu, X., Wiegand, A., Boltz, V. F., Swanson, P., Bream, J. H., Jacobson, L. P., Li, X., Rinaldo, C. R., Wolinsky, S. M., Coffin, J. M. & Mellors, J. W. 2011 In : Advances in Virology. 2011, 268214

Research output: Contribution to journalArticle

Nucleic Acids
HIV Infections
HIV-1
Viruses
Antibodies

Relationship between cytomegalovirus (CMV) IgG serology, detectable CMV DNA in peripheral monocytes, and CMV pp65 495-503-specific CD8 + T cells in older adults

Leng, S. X., Qu, T., Semba, R. D., Li, H., Yao, X., Nilles, T., Yang, X., Manwani, B., Walston, J. D., Ferrucci, L., Fried, L. P., Margolick, J. B. & Bream, J. H. Dec 2011 In : Age. 33, 4, p. 607-614 8 p.

Research output: Contribution to journalArticle

Cytomegalovirus
Monocytes
Immunoglobulin G
T-Lymphocytes
DNA

Serologic responses to pneumocystis proteins in HIV patients with and without pneumocystis jirovecii pneumonia

Gingo, M. R., Lucht, L., Daly, K. R., Djawe, K., Palella, F. J., Abraham, A. G., Bream, J. H., Witt, M. D., Kingsley, L. A., Norris, K. A., Walzer, P. D. & Morris, A. Jul 1 2011 In : Journal of Acquired Immune Deficiency Syndromes. 57, 3, p. 190-196 7 p.

Research output: Contribution to journalArticle

Pneumocystis
Pneumocystis jirovecii
Human Immunodeficiency Virus Proteins
Pneumocystis Pneumonia
Immunoglobulin G
2010

Cell type-specific regulation of IL-10 expression in inflammation and disease

Hedrich, C. M. & Bream, J. H. Jul 2010 In : Immunologic Research. 47, 1-3, p. 185-206 22 p.

Research output: Contribution to journalArticle

Interleukin-10
Inflammation
Disease Susceptibility
Adaptive Immunity
Autoimmune Diseases

Dynamic DNA methylation patterns across the mouse and human IL10 genes during CD4+ T cell activation; influence of IL-27

Hedrich, C. M., Ramakrishnan, A., Dabitao, D., Wang, F., Ranatunga, D. & Bream, J. H. Nov 2010 In : Molecular Immunology. 48, 1-3, p. 73-81 9 p.

Research output: Contribution to journalArticle

Interleukin-27
DNA Methylation
Interleukin-10
T-Lymphocytes
Genes
2009

A human IL10 BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome

Ranatunga, D., Hedrich, C. M., Fengying, W., McVicar, D. W., Nowak, N., Joshi, T., Feigenbaum, L., Grant, L. R., Stäger, S. & Bream, J. H. Oct 6 2009 In : Proceedings of the National Academy of Sciences of the United States of America. 106, 40, p. 17123-17128 6 p.

Research output: Contribution to journalArticle

Transgenes
Interleukin-10
Bacterial Artificial Chromosomes
Transgenic Mice
Genes

Long-term serologic responses to the pneumocystis jirovecii major surface glycoprotein in HIV-positive individuals with and without p. jirovecii infection

Walzer, P. D., Djawe, K., Levin, L., Daly, K. R., Koch, J., Kingsley, L., Witt, M., Golub, E. T., Bream, J. H., Taiwo, B. & Morris, A. May 1 2009 In : Journal of Infectious Diseases. 199, 9, p. 1335-1344 10 p.

Research output: Contribution to journalArticle

Pneumocystis jirovecii
Pneumocystis Pneumonia
Membrane Glycoproteins
HIV
Antibodies

Microbial translocation, the innate cytokine response, and HIV-1 disease progression in Africa

Redd, A. D., Dabitao, D., Bream, J. H., Charvat, B., Laeyendecker, O., Kiwanuka, N., Lutalo, T., Kigozi, G., Tobian, A. A. R., Gamiel, J., Neal, J. D., Oliver, A. E., Margolick, J. B., Sewankambo, N., Reynolds, S. J., Wawer, M. J., Serwadda, D., Gray, R. H. & Quinn, T. C. Apr 21 2009 In : Proceedings of the National Academy of Sciences of the United States of America. 106, 16, p. 6718-6723 6 p.

Research output: Contribution to journalArticle

Disease Progression
HIV-1
Cytokines
Uganda
Endotoxins

Mitochondrial DNA haplogroups influence lipoatrophy after highly active antiretroviral therapy

Hendrickson, S. L., Kingsley, L. A., Ruiz-Pesini, E., Poole, J. C., Jacobson, L. P., Palella, F. J., Bream, J. H., Wallace, D. C. & O'Brien, S. J. Jun 2009 In : Journal of Acquired Immune Deficiency Syndromes. 51, 2, p. 111-116 6 p.

Research output: Contribution to journalArticle

Highly Active Antiretroviral Therapy
Mitochondrial DNA
Odds Ratio
Confidence Intervals
Buttocks
2008

Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signaling

Reddy, N. M., Kleeberger, S. R., Bream, J. H., Fallon, P. G., Kensler, T. W., Yamamoto, M. & Reddy, S. P. Oct 2 2008 In : Oncogene. 27, 44, p. 5821-5832 12 p.

Research output: Contribution to journalArticle

Oxidation-Reduction
Cell Cycle
Maturation-Promoting Factor
Oxidative Stress
Cell Proliferation

Stat4-dependent, T-bet-independent regulation of IL-10 in NK cells

Grant, L. R., Yao, Z. J., Hedrich, C. M., Wang, F., Moorthy, A., Wilson, K., Ranatunga, D. & Bream, J. H. Jun 2008 In : Genes and Immunity. 9, 4, p. 316-327 12 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Interleukin-10
Interleukin-12
Interferon-gamma
Interleukin-2
2007

FcγRIIa genotype predicts progression of HIV infection

Forthal, D. N., Landucci, G., Bream, J., Jacobson, L. P., Phan, T. B. & Montoya, B. Dec 1 2007 In : Journal of Immunology. 179, 11, p. 7916-7923 8 p.

Research output: Contribution to journalArticle

HIV Infections
Genotype
Cell Count
Immunoglobulin G
Genes
Interferon-gamma
Messenger RNA
Proteins
Protein Folding
RNA Stability

IL-4 induces a wide-spectrum intracellular signaling cascade in CD8 + T cells

De Sa Pinheiro, A. A., Morrot, A., Chakravarty, S., Overstreet, M., Bream, J. H., Irusta, P. M. & Zavala, F. Apr 2007 In : Journal of Leukocyte Biology. 81, 4, p. 1102-1110 9 p.

Research output: Contribution to journalArticle

Interleukin-4
T-Lymphocytes
Interleukin-4 Receptors
Phosphorylation
Proto-Oncogene Proteins c-akt
Lipopolysaccharides
Reactive Oxygen Species
Blood Cells
Neutrophils
Genes