1983 …2019
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Fingerprint Dive into the research topics where James Sham is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 12 Similar Profiles
Smooth Muscle Myocytes Medicine & Life Sciences
Lung Medicine & Life Sciences
Muscle Cells Medicine & Life Sciences
Pulmonary Artery Medicine & Life Sciences
Endothelin-1 Medicine & Life Sciences
Ryanodine Receptor Calcium Release Channel Medicine & Life Sciences
Pulmonary Hypertension Medicine & Life Sciences
Sarcoplasmic Reticulum Medicine & Life Sciences

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Research Output 1983 2019

Leptin Induces Hypertension Acting on Transient Receptor Potential Melastatin 7 Channel in the Carotid Body

Shin, M. K., Eraso, C. C., Mu, Y. P., Gu, C., Yeung, B. H. Y., Kim, L. J., Liu, X. R., Wu, Z. J., Paudel, O., Pichard, L. E., Shirahata, M., Tang, W. Y., Sham, J. S. K. & Polotsky, V. Y., Nov 8 2019, In : Circulation research. 125, 11, p. 989-1002 14 p.

Research output: Contribution to journalArticle

Carotid Body
Leptin
Hypertension
Inbred C57BL Mouse
Transient Receptor Potential Channels

Intraluminal pressure triggers myogenic response via activation of calcium spark and calcium-activated chloride channel in rat renal afferent arteriole

Yip, K. P., Balasubramanian, L., Kan, C., Wang, L., Liu, R., Ribeiro-Silva, L. & Sham, J., Dec 1 2018, In : American Journal of Physiology - Renal Physiology. 315, 6, p. F1592-F1600

Research output: Contribution to journalArticle

Chloride Channels
Calcium Signaling
Arterioles
Vascular Smooth Muscle
Smooth Muscle Myocytes

Leptin acts in the carotid bodies to increase minute ventilation during wakefulness and sleep and augment the hypoxic ventilatory response

Caballero-Eraso, C., Shin, M-K., Pho, H., Kim, L. J., Pichard, L. E., Wu, Z. J., Gu, C., Berger, S., Pham, L., Yeung, H. Y. B., Shirahata, M., Schwartz, A. R., Tang, W-Y., Sham, J. & Polotsky, V., Jan 1 2018, (Accepted/In press) In : Journal of Physiology.

Research output: Contribution to journalArticle

Carotid Body
Wakefulness
Leptin
Ventilation
Sleep

Magnesium attenuates endothelin-1-induced vasoreactivity and enhances vasodilatation in mouse pulmonary arteries: Modulation by chronic hypoxic pulmonary hypertension

Mu, Y. P., Huang, Q. H., Zhu, J. L., Zheng, S. Y., Yan, F. R., Zhuang, X. L., Sham, J. & Lin, M. J., Jan 1 2018, (Accepted/In press) In : Experimental Physiology.

Research output: Contribution to journalArticle

Endothelin-1
Pulmonary Hypertension
Vasodilation
Magnesium
Pulmonary Artery
Pulmonary Artery
Calcium
Lung
Smooth Muscle Myocytes
Pulmonary Hypertension