James M Berger

Professor

1992 …2019
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where James M Berger is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 11 Similar Profiles
DNA Medicine & Life Sciences
Type II DNA Topoisomerase Medicine & Life Sciences
Adenosine Triphosphate Medicine & Life Sciences
Adenosine Triphosphatases Medicine & Life Sciences
Proteins Medicine & Life Sciences
Enzymes Medicine & Life Sciences
DNA Replication Medicine & Life Sciences
DNA Gyrase Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1992 2019

A complex suite of loci and elements in eukaryotic type II topoisomerases determine selective sensitivity to distinct poisoning agents

Blower, T. R., Bandak, A., Lee, A. S. Y., Austin, C. A., Nitiss, J. L. & Berger, J. M., Sep 5 2019, In : Nucleic acids research. 47, 15, p. 8163-8179 17 p.

Research output: Contribution to journalArticle

Open Access
Type II DNA Topoisomerase
Poisoning
Poisons
Pharmaceutical Preparations
Yeasts

Caught in the Open: A Domain Insertion of M. tuberculosis Gyrase Suppresses ATPase Dimerization

Hobson, M. J. & Berger, J. M., Apr 2 2019, In : Structure. 27, 4, p. 561-563 3 p.

Research output: Contribution to journalShort survey

Adenylyl Imidodiphosphate
Dimerization
Adenosine Triphosphatases
Tuberculosis
Enzymes

Design, synthesis and molecular docking of new N-4-piperazinyl ciprofloxacin-triazole hybrids with potential antimicrobial activity

Mohammed, H. H. H., Abdelhafez, E. S. M. N., Abbas, S. H., Moustafa, G. A. I., Hauk, G., Berger, J. M., Mitarai, S., Arai, M., Abd El-Baky, R. M. & Abuo-Rahma, G. E. D. A., Jul 1 2019, In : Bioorganic Chemistry. 88, 102952.

Research output: Contribution to journalArticle

Triazoles
Ciprofloxacin
Assays
Smegma
DNA Gyrase

Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome

Eickhoff, P., Kose, H. B., Martino, F., Petojevic, T., Abid Ali, F., Locke, J., Tamberg, N., Nans, A., Berger, J. M., Botchan, M. R., Yardimci, H. & Costa, A., Sep 3 2019, In : Cell Reports. 28, 10, p. 2673-2688.e8

Research output: Contribution to journalArticle

Open Access
Hydrolysis
Adenosine Triphosphate
DNA
Multicarrier modulation
Adenosine Triphosphatases

New fluoroquinolones/nitric oxide donor hybrids: design, synthesis and antitubercular activity

Aziz, H. A., Moustafa, G. A. I., Abbas, S. H., Hauk, G., Siva Krishna, V., Sriram, D., Berger, J. M. & Abuo-Rahma, G. E. D. A., Jan 1 2019, In : Medicinal Chemistry Research.

Research output: Contribution to journalArticle

Nitric Oxide Donors
Fluoroquinolones
Nitric Oxide
Nitrates
Esters