James Handa


1987 …2019
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Macular Degeneration Medicine & Life Sciences
Retinal Pigments Medicine & Life Sciences
Retinal Pigment Epithelium Medicine & Life Sciences
Epithelial Cells Medicine & Life Sciences
Bruch Membrane Medicine & Life Sciences
Oxidative Stress Medicine & Life Sciences
Retina Medicine & Life Sciences
Vitreoretinal Surgery Medicine & Life Sciences

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Research Output 1987 2019

A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration

Handa, J., Bowes Rickman, C., Dick, A. D., Gorin, M. B., Miller, J. W., Toth, C. A., Ueffing, M., Zarbin, M. & Farrer, L. A., Dec 1 2019, In : Nature communications. 10, 1, 3347.

Research output: Contribution to journalArticle

Open Access
Systems Biology
Macular Degeneration

Clarin-1 expression in adult mouse and human retina highlights a role of Müller glia in Usher syndrome

Xu, L., Bolch, S. N., Santiago, C. P., Dyka, F. M., Akil, O., Lobanova, E. S., Wang, Y., Martemyanov, K. A., Hauswirth, W. W., Smith, W. C., Handa, J. T., Blackshaw, S., Ash, J. D. & Dinculescu, A., Jan 1 2019, (Accepted/In press) In : Journal of Pathology.

Research output: Contribution to journalArticle

Open Access
Usher Syndromes
RNA Sequence Analysis
Retinal Vein Occlusion
Macular Edema
Vascular Endothelial Growth Factor A
Visual Acuity

Modulating EGFR-MTORC1-autophagy as a potential therapy for persistent fetal vasculature (PFV) disease

Yazdankhah, M., Shang, P., Ghosh, S., Bhutto, I. A., Stepicheva, N., Grebe, R., Hose, S., Weiss, J., Luo, T., Mishra, S., Riazuddin, S. A., Ghosh, A., Handa, J. T., Lutty, G. A., Zigler, J. S. & Sinha, D., Jan 1 2019, (Accepted/In press) In : Autophagy.

Research output: Contribution to journalArticle

Fetal Diseases
Epidermal Growth Factor Receptor

Neutrophils homing into the retina trigger pathology in early age-related macular degeneration

Ghosh, S., Padmanabhan, A., Vaidya, T., Watson, A. M., Bhutto, I. A., Hose, S., Shang, P., Stepicheva, N., Yazdankhah, M., Weiss, J., Das, M., Gopikrishna, S., Aishwarya, Yadav, N., Berger, T., Mak, T. W., Xia, S., Qian, J., Lutty, G. A., Jayagopal, A. & 6 others, Zigler, J. S., Sethu, S., Handa, J. T., Watkins, S. C., Ghosh, A. & Sinha, D., Dec 1 2019, In : Communications Biology. 2, 1, 348.

Research output: Contribution to journalArticle

Open Access
Macular Degeneration