James Handa

Professor

1987 …2019
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where James Handa is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 15 Similar Profiles
Macular Degeneration Medicine & Life Sciences
Retinal Pigments Medicine & Life Sciences
Retinal Pigment Epithelium Medicine & Life Sciences
Epithelial Cells Medicine & Life Sciences
Bruch Membrane Medicine & Life Sciences
Oxidative Stress Medicine & Life Sciences
Retina Medicine & Life Sciences
Vitreoretinal Surgery Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1987 2019

A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration

Handa, J., Bowes Rickman, C., Dick, A. D., Gorin, M. B., Miller, J. W., Toth, C. A., Ueffing, M., Zarbin, M. & Farrer, L. A., Dec 1 2019, In : Nature communications. 10, 1, 3347.

Research output: Contribution to journalArticle

Open Access
Systems Biology
degeneration
Macular Degeneration
biology
therapy

Loss of Peak Vision in Retinal Vein Occlusion Patients Treated for Macular Edema

Iftikhar, M., Mir, T. A., Hafiz, G., Zimmer Galler, I. E., Scott, A., Solomon, S. D., Sodhi, A., Wenick, A., Meyerle, C., Jiramongkolchai, K., Liu, T. Y., Arevalo, J. F., Singh, M., Kherani, S., Handa, J. & Campochiaro, P. A., Sep 1 2019, In : American journal of ophthalmology. 205, p. 17-26 10 p.

Research output: Contribution to journalArticle

Retinal Vein Occlusion
Macular Edema
Vascular Endothelial Growth Factor A
Visual Acuity
Edema

Modulating EGFR-MTORC1-autophagy as a potential therapy for persistent fetal vasculature (PFV) disease

Yazdankhah, M., Shang, P., Ghosh, S., Bhutto, I. A., Stepicheva, N., Grebe, R., Hose, S., Weiss, J., Luo, T., Mishra, S., Riazuddin, S. A., Ghosh, A., Handa, J., Lutty, G. A., Zigler, J. S. & Sinha, D., Jan 1 2019, (Accepted/In press) In : Autophagy.

Research output: Contribution to journalArticle

Fetal Diseases
Autophagy
Epidermal Growth Factor Receptor
Phosphotransferases
Astrocytes

The selective estrogen receptor modulator raloxifene mitigates the effect of all-trans-retinal toxicity in photoreceptor degeneration

Getter, T., Suh, S., Hoang, T., Handa, J., Dong, Z., Ma, X., Chen, Y., Blackshaw, S. & Palczewski, K., Jan 1 2019, In : Journal of Biological Chemistry. 294, 24, p. 9461-9475 15 p.

Research output: Contribution to journalArticle

Selective Estrogen Receptor Modulators
Toxicity
Calcium
Retina
Assays

A Role for βA3/A1-Crystallin in Type 2 EMT of RPE Cells Occurring in Dry Age-Related Macular Degeneration

Ghosh, S., Shang, P., Terasaki, H., Stepicheva, N., Hose, S., Yazdankhah, M., Weiss, J., Sakamoto, T., Bhutto, I. A., Xia, S., Zigler, J. S., Kannan, R., Qian, J., Handa, J. & Sinha, D., Mar 20 2018, In : Investigative ophthalmology & visual science. 59, 4, p. AMD104-AMD113

Research output: Contribution to journalArticle

Crystallins
Epithelial-Mesenchymal Transition
Macular Degeneration
Vimentin
Cadherins