James Eshleman

Professor

1988 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2011

Mutant proteins as cancer-specific biomarkers

Wang, Q., Chaerkady, R., Wu, J., Hwang, H. J., Papadopoulos, N., Kopelovich, L., Maitra, A., Matthaei, H., Eshleman, J. R., Hruban, R. H., Kinzler, K. W., Pandey, A. & Vogelstein, B., Feb 8 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 6, p. 2444-2449 6 p.

Research output: Contribution to journalArticle

Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer

Villarroel, M. C., Rajeshkumar, N. V., Garrido-Laguna, I., De Jesus-Acosta, A., Jones, S., Maitra, A., Hruban, R. H., Eshleman, J. R., Klein, A., Laheru, D., Donehower, R. & Hidalgo, M., Jan 1 2011, In : Molecular cancer therapeutics. 10, 1, p. 3-8 6 p.

Research output: Contribution to journalArticle

Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development

Wu, J., Matthaei, H., Maitra, A., Dal Molin, M., Wood, L. D., Eshleman, J. R., Goggins, M., Canto, M. I., Schulick, R. D., Edil, B. H., Wolfgang, C. L., Klein, A. P., Diaz, L. A., Allen, P. J., Schmidt, C. M., Kinzler, K. W., Papadopoulos, N., Hruban, R. H. & Vogelstein, B., Jul 20 2011, In : Science translational medicine. 3, 92, 92ra66.

Research output: Contribution to journalArticle

Sarcina organisms in the gastrointestinal tract: A clinicopathologic and molecular study

Lam-Himlin, D., Tsiatis, A. C., Montgomery, E., Pai, R. K., Brown, J. A., Razavi, M., Lamps, L., Eshleman, J. R., Bhagavan, B. & Anders, R. A., Nov 1 2011, In : American Journal of Surgical Pathology. 35, 11, p. 1700-1705 6 p.

Research output: Contribution to journalArticle

Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways

Wu, J., Jiao, Y., Dal Molin, M., Maitra, A., De Wilde, R. F., Wood, L. D., Eshleman, J. R., Goggins, M. G., Wolfgang, C. L., Canto, M. I., Schulick, R. D., Edil, B. H., Choti, M. A., Adsay, V., Klimstra, D. S., Offerhaus, G. J. A., Klein, A. P., Kopelovich, L., Carter, H., Karchin, R. & 8 others, Allen, P. J., Schmidt, C. M., Naito, Y., Diaz, L. A., Kinzler, K. W., Papadopoulos, N., Hruban, R. H. & Vogelstein, B., Dec 27 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 52, p. 21188-21193 6 p.

Research output: Contribution to journalArticle

Δ-PCR, a simple method to detect translocations and insertion/deletion mutations

Lin, M. T., Tseng, L. H., Rich, R. G., Hafez, M. J., Harada, S., Murphy, K. M., Eshleman, J. R. & Gocke, C. D., Jan 2011, In : Journal of Molecular Diagnostics. 13, 1, p. 85-92 8 p.

Research output: Contribution to journalArticle

2010

Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis for the detection of KRAS mutations: Diagnostic and clinical implications

Tsiatis, A. C., Norris-Kirby, A., Rich, R. G., Hafez, M. J., Gocke, C. D., Eshleman, J. R. & Murphy, K. M., Jul 1 2010, In : Journal of Molecular Diagnostics. 12, 4, p. 425-432 8 p.

Research output: Contribution to journalArticle

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

Yachida, S., Jones, S., Bozic, I., Antal, T., Leary, R., Fu, B., Kamiyama, M., Hruban, R. H., Eshleman, J. R., Nowak, M. A., Velculescu, V. E., Kinzler, K. W., Vogelstein, B. & Iacobuzio-Donahue, C. A., Oct 28 2010, In : Nature. 467, 7319, p. 1114-1117 4 p.

Research output: Contribution to journalArticle

International network of cancer genome projects

Hudson, T. J., Anderson, W., Aretz, A., Barker, A. D., Bell, C., Bernabé, R. R., Bhan, M. K., Calvo, F., Eerola, I., Gerhard, D. S., Guttmacher, A., Guyer, M., Hemsley, F. M., Jennings, J. L., Kerr, D., Klatt, P., Kolar, P., Kusuda, J., Lane, D. P., Laplace, F. & 241 others, Lu, Y., Nettekoven, G., Ozenberger, B., Peterson, J., Rao, T. S., Remacle, J., Schafer, A. J., Shibata, T., Stratton, M. R., Vockley, J. G., Watanabe, K., Yang, H., Yuen, M. M. F., Knoppers, B. M., Bobrow, M., Cambon-Thomsen, A., Dressler, L. G., Dyke, S. O. M., Joly, Y., Kato, K., Kennedy, K. L., Nicolás, P., Parker, M. J., Rial-Sebbag, E., Romeo-Casabona, C. M., Shaw, K. M., Wallace, S., Wiesner, G. L., Zeps, N., Lichter, P., Biankin, A. V., Chabannon, C., Chin, L., Clément, B., Alava, E. D., Degos, F., Ferguson, M. L., Geary, P., Hayes, D. N., Johns, A. L., Kasprzyk, A., Nakagawa, H., Penny, R., Piris, M. A., Sarin, R., Scarpa, A., De Vijver, M. V., Futreal, P. A., Aburatani, H., Bayés, M., Bowtell, D. D. L., Campbel, P. J., Estivill, X., Grimmond, S. M., Gut, I., Hirst, M., López-Otý́n, C., Majumder, P., Marra, M., McPherson, J. D., Ning, Z., Puente, X. S., Ruan, Y., Stunnenberg, H. G., Swerdlow, H., Velculescu, V. E., Wilson, R. K., Xue, H. H., Yang, L., Spellman, P. T., Bader, G. D., Boutros, P. C., Flicek, P., Getz, G., Guigó, R., Guo, G., Haussler, D., Heath, S., Hubbard, T. J., Jiang, T., Jones, S. M., Li, Q., López-Bigas, N., Luo, R., Muthuswamy, L., Ouellette, B. F. F., Pearson, J. V., Quesada, V., Raphael, B. J., Sander, C., Speed, T. P., Stein, L. D., Stuart, J. M., Teague, J. W., Totoki, Y., Tsunoda, T., Valencia, A., Wheeler, D. A., Wu, H., Zhao, S., Zhou, G., Lathrop, M., Thomas, G., Yoshida, T., Axton, M., Gunter, C., Miller, L. J., Zhang, J., Haider, S. A., Wang, J., Yung, C. K., Cross, A., Liang, Y., Gnaneshan, S., Guberman, J., Hsu, J., Chalmers, D. R. C., Hasel, K. W., Kaan, T. S. H., Lowrance, W. W., Masui, T., Rodriguez, L. L., Vergely, C., Bowtel, D. D. L., Cloonan, N., DeFazio, A., Eshleman, J. R., Etemadmoghadam, D., Gardiner, B. A., Kench, J. G., Sutherland, R. L., Tempero, M. A., Waddell, N. J., Wilson, P. J., Gallinger, S., Tsao, M. S., Shaw, P. A., Petersen, G. M., Mukhopadhyay, D., DePinho, R. A., Thayer, S., Shazand, K., Beck, T., Sam, M., Timms, L., Ballin, V., Ji, J., Zhang, X., Chen, F., Hu, X., Yang, Q., Tian, G., Zhang, L., Xing, X., Li, X., Zhu, Z., Yu, Y., Yu, J., Tost, J., Brennan, P., Holcatova, I., Zaridze, D., Brazma, A., Egevad, L., Prokhortchouk, E., Banks, R. E., Uhlén, M., Viksna, J., Ponten, F., Skryabin, K., Futrea, P. A., Birney, E., Borg, A., Børresen-Dale, A. L., Caldas, C., Foekens, J. A., Martin, S., Reis-Filho, J. S., Richardson, A. L., Sotiriou, C., Veer, L. V. T., Birnbaum, D., Blanche, H., Boucher, P., Boyault, S., Masson-Jacquemier, J. D., Pauporté, I., Pivot, X., Vincent-Salomon, A., Tabone, E., Theillet, C., Treilleux, I., Bioulac-Sage, P., Decaens, T., OiseDegos, F., Franco, D., Gut, M., Samuel, D., Zucman-Rossi, J., Eils, R., Brors, B., Korbe, J. O., Korshunov, A., Landgraf, P., Lehrach, H., Pfister, S., Radlwimmer, B., Reifenberger, G., Taylor, M. D., Kalle, C. V., Majumder, P. P., Rao, T. S., Pederzoli, P., Lawlor, R. T., Delledonne, M., Bardelli, A., Gress, T., Klimstra, D., Zamboni, G., Nakamura, Y., Miyano, S., Fujimoto, A., Campo, E., Sanjosé, S. D., Montserrat, E., González-Dý́az, M., Jares, P., Himmelbaue, H., Bea, S., Aparicio, S., Easton, D. F., Collins, F. S., Compton, C. C., Lander, E. S., Burke, W., Green, A. R., Hamilton, S. R., Kallioniemi, O. P., Ley, T. J., Liu, E. T. & Wainwright, B. J., Apr 15 2010, In : Nature. 464, 7291, p. 993-998 6 p.

Research output: Contribution to journalReview article

In vivo and in vitro propagation of intraductal papillary mucinous neoplasms

Kamiyama, H., Kamiyama, M., Hong, S. M., Karikari, C. A., Lin, M. T., Borges, M. W., Griffith, M., Young, A., Norris-Kirby, A., Lubek, C., Mizuma, M., Feldmann, G., Shi, C., Liang, H., Goggins, M. G., Maitra, A., Hruban, R. H. & Eshleman, J. R., May 1 2010, In : Laboratory Investigation. 90, 5, p. 665-673 9 p.

Research output: Contribution to journalArticle

Quantifying the relative amount of mouse and human DNA in cancer xenografts using species-specific variation in gene length

Lin, M. T., Tseng, L. H., Kamiyama, H., Kamiyama, M., Lim, P., Hidalgo, M., Wheelan, S. & Eshleman, J. R., Mar 1 2010, In : BioTechniques. 48, 3, p. 351-355 5 p.

Research output: Contribution to journalArticle

The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma

Alvarez, H., Montgomery, E. A., Karikari, C., Canto, M., Dunbar, K. B., Wang, J. S., Feldmann, G., Hong, S. M., Haffner, M. C., Meeker, A. K., Holland, S. J., Yu, J., Heckrodt, T. J., Zhang, J., Ding, P., Goff, D., Singh, R., Roa, J. C., Marimuthu, A., Riggins, G. J. & 4 others, Eshleman, J. R., Nelkin, B. D., Pandey, A. & Maitra, A., Nov 15 2010, In : Cancer Biology and Therapy. 10, 10, p. 1009-1018 10 p.

Research output: Contribution to journalArticle

Verification and unmasking of widely used human esophageal adenocarcinoma cell lines

Boonstra, J. J., Van Marion, R., Beer, D. G., Lin, L., Chaves, P., Ribeiro, C., Pereira, A. D., Roque, L., Darnton, S. J., Altorki, N. K., Schrump, D. S., Klimstra, D. S., Tang, L. H., Eshleman, J. R., Alvarez, H., Shimada, Y., Van Dekken, H., Tilanus, H. W. & Dinjens, W. N. M., Feb 1 2010, In : Journal of the National Cancer Institute. 102, 4, p. 271-274 4 p.

Research output: Contribution to journalArticle

2009

Benign nodal nevi frequently harbor the activating V600E BRAF mutation

Taube, J. M., Begum, S., Shi, C., Eshleman, J. R. & Westra, W. H., Apr 1 2009, In : American Journal of Surgical Pathology. 33, 4, p. 568-571 4 p.

Research output: Contribution to journalArticle

DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer

Lacobuzio-Donahue, C. A., Fu, B., Yachida, S., Luo, M., Abe, H., Henderson, C. M., Vilardell, F., Wang, Z., Keller, J. W., Banerjee, P., Herman, J. M., Cameron, J. L., Yeo, C. J., Halushka, M. K., Eshleman, J. R., Raben, M., Klein, A. P., Hruban, R. H., Hidalgo, M. & Laheru, D., Apr 10 2009, In : Journal of Clinical Oncology. 27, 11, p. 1806-1813 8 p.

Research output: Contribution to journalArticle

Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene

Jones, S., Hruban, R. H., Kamiyama, M., Borges, M., Zhang, X., Parsons, D. W., Lin, J. C. H., Palmisano, E., Brune, K., Jaffee, E. M., Iacobuzio-Donahue, C. A., Maitra, A., Parmigiani, G., Kern, S. E., Velculescu, V. E., Kinzler, K. W., Vogelstein, B., Eshleman, J. R., Goggins, M. & Klein, A. P., Apr 10 2009, In : Science. 324, 5924, 1 p.

Research output: Contribution to journalArticle

Genetic mutations associated with Cigarette smoking in pancreatic cancer

Blackford, A., Parmigiani, G., Kensler, T. W., Wolfgang, C., Jones, S., Zhang, X., Parsons, D. W., Lin, J. C. H., Leary, R. J., Eshleman, J. R., Goggins, M., Jaffee, E. M., Iacobuzio-Donahue, C. A., Maitra, A., Klein, A., Cameron, J. L., Olino, K., Schulick, R., Winter, J., Vogelstein, B. & 3 others, Velculescu, V. E., Kinzler, K. W. & Hruban, R. H., Apr 15 2009, In : Cancer Research. 69, 8, p. 3681-3688 8 p.

Research output: Contribution to journalArticle

Limits to thymidylate synthase and TP53 genes as predictive determinants for fluoropyrimidine sensitivity and further evidence for RNA-based toxicity as a major influence

Brody, J. R., Hucl, T., Costantino, C. L., Eshleman, J. R., Gallmeier, E., Zhu, H., Van Der Heijden, M. S., Winter, J. M., Wikiewicz, A. K., Yeo, C. J. & Kern, S. E., Feb 1 2009, In : Cancer Research. 69, 3, p. 984-991 8 p.

Research output: Contribution to journalArticle

SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer

Blackford, A., Serrano, O. K., Wolfgang, C. L., Parmigiani, G., Jones, S., Zhang, X., Parsons, D. W., Lin, J. C. H., Leary, R. J., Eshleman, J. R., Goggins, M., Jaffee, E. M., Iacobuzio-Donahue, C. A., Maitra, A., Cameron, J. L., Olino, K., Schulick, R., Winter, J., Herman, J. M., Laheru, D. & 5 others, Klein, A. P., Vogelstein, B., Kinzler, K. W., Velculescu, V. E. & Hruban, R. H., Jul 15 2009, In : Clinical Cancer Research. 15, 14, p. 4674-4679 6 p.

Research output: Contribution to journalArticle

Ultrasensitive detection of KRAS2 mutations in bile and serum from patients with biliary tract carcinoma using LigAmp technology

Shi, C., Chandrasekaran, A., Thuluvath, P. J., Karikari, C., Argani, P., Goggins, M., Maitra, A. & Eshleman, J. R., Nov 2009, In : Journal of Molecular Diagnostics. 11, 6, p. 583-589 7 p.

Research output: Contribution to journalArticle

2008

An Inactivating Mutation in HDAC2 Leads to Dysregulation of Apoptosis Mediated by APAF1

Hanigan, C. L., van Engeland, M., De Bruine, A. P., Wouters, K. A., Weijenberg, M. P., Eshleman, J. R. & Herman, J. G., Nov 2008, In : Gastroenterology. 135, 5, p. 1654-1664.e2

Research output: Contribution to journalArticle

Anti-gene padlocks eliminate Escherichia coli based on their genotype

Shi, C., Parker, A. R., Hua, L., Morrell, C. N., Lee, S. C., Bandaru, V., Dumler, J. S., Wu, T. C. & Eshleman, J. R., Feb 1 2008, In : Journal of Antimicrobial Chemotherapy. 61, 2, p. 262-272 11 p.

Research output: Contribution to journalArticle

Application of traditional clinical pathology quality control techniques to molecular pathology

Liang, S. L., Lin, M. T., Hafez, M. J., Gocke, C. D., Murphy, K. M., Sokoll, L. J. & Eshleman, J. R., Mar 2008, In : Journal of Molecular Diagnostics. 10, 2, p. 142-146 5 p.

Research output: Contribution to journalArticle

Comparison of LigAmp and an ASPCR assay for detection and quantification of K103N-containing HIV variants

Church, J. D., Towler, W. I., Hoover, D. R., Hudelson, S. E., Kumwenda, N., Taha, T. E., Eshleman, J. R. & Eshleman, S. H., Apr 1 2008, In : AIDS research and human retroviruses. 24, 4, p. 595-605 11 p.

Research output: Contribution to journalArticle

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

Jones, S., Zhang, X., Parsons, D. W., Lin, J. C. H., Leary, R. J., Angenendt, P., Mankoo, P., Carter, H., Kamiyama, H., Jimeno, A., Hong, S. M., Fu, B., Lin, M. T., Calhoun, E. S., Kamiyama, M., Walter, K., Nikolskaya, T., Nikolsky, Y., Hartigan, J., Smith, D. R. & 16 others, Hidalgo, M., Leach, S. D., Klein, A. P., Jaffee, E. M., Goggins, M., Maitra, A., Iacobuzio-Donahue, C., Eshleman, J. R., Kern, S. E., Hruban, R. H., Karchin, R., Papadopoulos, N., Parmigiani, G., Vogelstein, B., Velculescu, V. E. & Kinzler, K. W., Sep 26 2008, In : Science. 321, 5897, p. 1801-1806 6 p.

Research output: Contribution to journalArticle

Differentiating alternative splice variant patterns of human telomerase reverse transcriptase in thyroid neoplasms

Wang, Y., Kowalski, J., Tsai, H. L., Marik, R., Prasad, N., Somervell, H., Lo, P. K., Sangenario, L. E., Dyrskjot, L., Orntoft, T. F., Westra, W. H., Meeker, A. K., Eshleman, J. R., Umbricht, C. B. & Zeiger, M. A., Oct 1 2008, In : Thyroid. 18, 10, p. 1055-1063 9 p.

Research output: Contribution to journalArticle

Establishment and characterization of a bona fide Barrett esophagus-associated adenocarcinoma cell line

Alvarez, H., Koorstra, J. B. M., Hong, S. M., Boonstra, J. J., Dinjens, W. N. M., Foratiere, A. A., Wu, T. T., Montgomery, E., Eshleman, J. R. & Maitra, A., Nov 2008, In : Cancer Biology and Therapy. 7, 11, p. 1753-1755 3 p.

Research output: Contribution to journalArticle

Genetic and epigenetic alterations of familial pancreatic cancers

Brune, K., Hong, S. M., Li, A., Yachida, S., Abe, T., Griffith, M., Yang, D., Omura, N., Eshleman, J., Canto, M., Schulick, R., Klein, A. P., Hruban, R. H., Iacobuzio-Donohue, C. & Goggins, M., Dec 1 2008, In : Cancer Epidemiology Biomarkers and Prevention. 17, 12, p. 3536-3542 7 p.

Research output: Contribution to journalArticle

Mesothelin is a specific biomarker of invasive cancer in the Barrett-associated adenocarcinoma progression model: translational implications for diagnosis and therapy

Alvarez, H., Rojas, P. L., Yong, K. T., Ding, H., Xu, G., Prasad, P. N., Wang, J., Canto, M., Eshleman, J. R., Montgomery, E. A. & Maitra, A., Dec 1 2008, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 4, 4, p. 295-301 7 p.

Research output: Contribution to journalArticle

Sensitive and quantitative detection of KRAS2 gene mutations in pancreatic duct juice differentiates patients with pancreatic cancer from chronic pancreatitis, potential for early detection

Shi, C., Fukushima, N., Abe, T., Bian, Y., Hua, L., Wendelburg, B. J., Yeo, C. J., Hruban, R. H., Goggins, M. G. & Eshleman, J. R., Mar 2008, In : Cancer Biology and Therapy. 7, 3, p. 353-360 8 p.

Research output: Contribution to journalArticle

Open Access
2007

A molecular fraction collecting tool for the ABI 310 automated sequencer

Lin, M. T., Rich, R. G., Shipley, R. F., Hafez, M. J., Tseng, L. H., Murphy, K. M., Gocke, C. D. & Eshleman, J. R., Nov 2007, In : Journal of Molecular Diagnostics. 9, 5, p. 598-603 6 p.

Research output: Contribution to journalArticle

Development of an integrated assay for detection of BCR-ABL RNA

Winn-Deen, E. S., Helton, B., Van Atta, R., Wong, W., Peralta, J., Wang, J., Tsongalis, G. J., Belloni, D., Chan, D., Eshleman, J. R., Gocke, C. D., Jobbagy, Z., Beppu, L. & Radich, J. P., Sep 1 2007, In : Clinical chemistry. 53, 9, p. 1593-1600 8 p.

Research output: Contribution to journalArticle

Evaluation of the Cepheid GeneXpert BCR-ABL assay

Jobbagy, Z., van Atta, R., Murphy, K. M., Eshleman, J. R. & Gocke, C. D., Apr 2007, In : Journal of Molecular Diagnostics. 9, 2, p. 220-227 8 p.

Research output: Contribution to journalArticle

Familial pancreatic cancer: from genes to improved patient care.

Hruban, R. H., Klein, A. P., Eshleman, J. R., Axilbund, J. E. & Goggins, M., Oct 2007, In : Expert review of gastroenterology & hepatology. 1, 1, p. 81-88 8 p.

Research output: Contribution to journalReview article

Palladin is overexpressed in the non-neoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells

Salaria, S. N., Illei, P., Sharma, R., Walter, K. M., Klein, A. P., Eshleman, J. R., Maitra, A., Schulick, R., Winter, J., Ouellette, M. M., Goggins, M. & Hruban, R., Mar 2007, In : Cancer Biology and Therapy. 6, 3, p. 324-328 5 p.

Research output: Contribution to journalArticle

Open Access
2006

An in vivo platform for translational drug development in pancreatic cancer

Rubio-Viqueira, B., Jimeno, A., Cusatis, G., Zhang, X., Iacobuzio-Donahue, C., Karikari, C., Shi, C., Danenberg, K., Danenberg, P. V., Kuramochi, H., Tanaka, K., Singh, S., Salimi-Moosavi, H., Bouraoud, N., Amador, M. L., Altiok, S., Kulesza, P., Yeo, C., Messersmith, W., Eshleman, J. & 3 others, Hruban, R. H., Maitra, A. & Hidalgo, M., Aug 1 2006, In : Clinical Cancer Research. 12, 15, p. 4652-4661 10 p.

Research output: Contribution to journalArticle

Comparison of the microsatellite instability analysis system and the Bethesda panel for the determination of microsatellite instability in colorectal cancers

Murphy, K. M., Zhang, S., Geiger, T., Hafez, M. J., Bacher, J., Berg, K. D. & Eshleman, J. R., Jul 2006, In : Journal of Molecular Diagnostics. 8, 3, p. 305-311 7 p.

Research output: Contribution to journalArticle

Copy-number methods dramatically underestimate loss of heterozygosity in cancer [1]

Calhoun, E. S., Gallmeier, E., Cunningham, S. C., Eshleman, J. R., Hruban, R. H. & Kern, S. E., Nov 1 2006, In : Genes Chromosomes and Cancer. 45, 11, p. 1070-1071 2 p.

Research output: Contribution to journalLetter

Differentiating pancreatic lesions by microarray and QPCR analysis of pancreatic juice RNAs

Rogers, C. D., Fukushima, N., Sato, N., Shi, C., Prasad, N., Hustinx, S. R., Matsubayashi, H., Canto, M., Eshleman, J. R., Hruban, R. H. & Goggins, M., Oct 2006, In : Cancer Biology and Therapy. 5, 10, p. 1383-1389 7 p.

Research output: Contribution to journalArticle

Open Access

Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: A biomarker for the early detection of cancer

Sui, G., Zhou, S., Wang, J., Canto, M., Lee, E. E., Eshleman, J. R., Montgomery, E. A., Sidransky, D., Califano, J. A. & Maitra, A., Dec 1 2006, In : Molecular Cancer. 5, 73.

Research output: Contribution to journalArticle

Oxidative stress and DNA damage - DNA repair system in vascular smooth muscle cells in artery and vein grafts

McLaren, S. H., Gao, D., Chen, L., Lin, R., Eshleman, J. R., Dawson, V., Trush, M. A., Bohr, V. A., Dizdaroglu, M., Williams, G. M. & Wei, C., Mar 1 2006, In : Journal of Cardiothoracic-Renal Research. 1, 1, p. 59-72 14 p.

Research output: Contribution to journalReview article

Sensitivity of the ViroSeq HIV-1 Genotyping System for detection of the K103N resistance mutation in HIV-1 subtypes A, C, and D

Church, J. D., Jones, D., Flys, T., Hoover, D., Marlowe, N., Chen, S., Shi, C., Eshleman, J. R., Guay, L. A., Jackson, B., Kumwenda, N., Taha, T. E. & Eshleman, S. H., Sep 2006, In : Journal of Molecular Diagnostics. 8, 4, p. 430-432 3 p.

Research output: Contribution to journalArticle

2005

A novel functionally deficient MYH variant in individuals with colorectal adenomatous polyposis.

Alhopuro, P., Parker, A. R., Lehtonen, R., Enholm, S., Järvinen, H. J., Mecklin, J. P., Karhu, A., Eshleman, J. R. & Aaltonen, L. A., Oct 2005, In : Human mutation. 26, 4, 1 p.

Research output: Contribution to journalArticle

Capillary electrophoresis artifact due to eosin: Implications for the interpretation of molecular diagnostic assays

Murphy, K. M., Berg, K. D., Geiger, T., Hafez, M., Flickinger, K. A., Cooper, L., Pearson, P. & Eshleman, J. R., Feb 2005, In : Journal of Molecular Diagnostics. 7, 1, p. 143-148 6 p.

Research output: Contribution to journalArticle

Cells with pathogenic biallelic mutations in the human MUTYH gene are defective in DNA damage binding and repair

Parker, A. R., Sieber, O. M., Shi, C., Hua, L., Takao, M., Tomlinson, I. P. & Eshleman, J. R., Nov 1 2005, In : Carcinogenesis. 26, 11, p. 2010-2018 9 p.

Research output: Contribution to journalArticle

Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and invasion of pancreatic ductal adenocarcinoma

Sato, N., Parker, A. R., Fukushima, N., Miyagi, Y., Iacobuzio-Donahue, C. A., Eshleman, J. R. & Goggins, M., Jan 27 2005, In : Oncogene. 24, 5, p. 850-858 9 p.

Research output: Contribution to journalArticle