James Eshleman

Professor

1988 …2020

Research output per year

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Research Output

2016

Nanopore sequencing detects structural variants in cancer

Norris, A. L., Workman, R. E., Fan, Y., Eshleman, J. R. & Timp, W., Mar 3 2016, In : Cancer Biology and Therapy. 17, 3, p. 246-253 8 p.

Research output: Contribution to journalArticle

Test feasibility of next-generation sequencing assays in clinical mutation detection of small biopsy and fine needle aspiration specimens

Zheng, G., Tsai, H., Tseng, L. H., Illei, P. B., Gocke, C., Eshleman, J., Netto, G. & Lin, M-T., May 1 2016, In : American Journal of Clinical Pathology. 145, 5, p. 696-702 7 p.

Research output: Contribution to journalArticle

Whole genome sequencing defines the genetic heterogeneity of familial pancreatic cancer

Roberts, N. J., Norris, A. L., Petersen, G. M., Bondy, M. L., Brand, R., Gallinger, S., Kurtz, R. C., Olson, S. H., Rustgi, A. K., Schwartz, A. G., Stoffel, E., Syngal, S., Zogopoulos, G., Ali, S. Z., Axilbund, J., Chaffee, K. G., Chen, Y. C., Cote, M. L., Childs, E. J., Douville, C. & 25 others, Goes, F. S., Herman, J. M., Iacobuzio-Donahue, C., Kramer, M., Makohon-Moore, A., McCombie, R. W., Wyatt Mcmahon, K., Niknafs, N., Parla, J., Pirooznia, M., Potash, J. B., Rhim, A. D., Smith, A. L., Wang, Y., Wolfgang, C. L., Wood, L. D., Zandi, P. P., Goggins, M., Karchin, R., Eshleman, J. R., Papadopoulos, N., Kinzler, K. W., Vogelstein, B., Hruban, R. H. & Klein, A. P., Feb 2016, In : Cancer discovery. 6, 2, p. 166-175 10 p.

Research output: Contribution to journalArticle

2015

A Combination of Molecular Markers and Clinical Features Improve the Classification of Pancreatic Cysts

Springer, S., Wang, Y., Dal Molin, M., Masica, D. L., Jiao, Y., Kinde, I., Blackford, A., Raman, S. P., Wolfgang, C. L., Tomita, T., Niknafs, N., Douville, C., Ptak, J., Dobbyn, L., Allen, P. J., Klimstra, D. S., Schattner, M. A., Schmidt, C. M., Yip-Schneider, M., Cummings, O. W. & 47 others, Brand, R. E., Zeh, H. J., Singhi, A. D., Scarpa, A., Salvia, R., Malleo, G., Zamboni, G., Falconi, M., Jang, J. Y., Kim, S. W., Kwon, W., Hong, S. M., Song, K. B., Kim, S. C., Swan, N., Murphy, J., Geoghegan, J., Brugge, W., Fernandez-Del Castillo, C., Mino-Kenudson, M., Schulick, R., Edil, B. H., Adsay, V., Paulino, J., Van Hooft, J., Yachida, S., Nara, S., Hiraoka, N., Yamao, K., Hijioka, S., Van Der Merwe, S., Goggins, M., Canto, M. I., Ahuja, N., Hirose, K., Makary, M., Weiss, M. J., Cameron, J., Pittman, M., Eshleman, J. R., Diaz, L. A., Papadopoulos, N., Kinzler, K. W., Karchin, R., Hruban, R. H., Vogelstein, B. & Lennon, A. M., Nov 2015, In : Gastroenterology. 149, 6, p. 1501-1510 10 p.

Research output: Contribution to journalArticle

Challenges posed to pathologists in the detection of KRAS mutations in colorectal cancers

Dudley, J., Tseng, L. H., Rooper, L., Harris, M., Haley, L., Chen, G., Gocke, C. D., Eshleman, J. R. & Lin, M. T., Feb 1 2015, In : Archives of Pathology and Laboratory Medicine. 139, 2, p. 211-218 8 p.

Research output: Contribution to journalArticle

Clinical detection and categorization of uncommon and concomitant mutations involving BRAF

Zheng, G., Tseng, L. H., Chen, G., Haley, L., Illei, P., Gocke, C. D., Eshleman, J. R. & Lin, M. T., Oct 24 2015, In : BMC cancer. 15, 1, 779.

Research output: Contribution to journalArticle

Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients

Sausen, M., Phallen, J., Adleff, V., Jones, S., Leary, R. J., Barrett, M. T., Anagnostou, V., Parpart-Li, S., Murphy, D., Li, Q. K., Hruban, C. A., Scharpf, R. B., White, J. R., O'Dwyer, P. J., Allen, P. J., Eshleman, J., Thompson, C. B., Klimstra, D. S., Linehan, D. C., Maitra, A. & 6 others, Hruban, R. H., Diaz, L. A., Von Hoff, D. D., Johansen, J. S., Drebin, J. A. & Velculescu, V. E., Jul 7 2015, In : Nature Communications. 6, 7686.

Research output: Contribution to journalArticle

KRAS and guanine nucleotide-binding protein mutations in pancreatic juice collected from the duodenum of patients at high risk for neoplasia undergoing endoscopic ultrasound

Eshleman, J. R., Norris, A. L., Sadakari, Y., Debeljak, M., Borges, M., Harrington, C., Lin, E., Brant, A., Barkley, T., Almario, J. A., Topazian, M., Farrell, J., Syngal, S., Lee, J. H., Yu, J., Hruban, R. H., Kanda, M., Canto, M. I. & Goggins, M., May 1 2015, In : Clinical Gastroenterology and Hepatology. 13, 5, p. 963-969.e4

Research output: Contribution to journalArticle

Lymph node metastases of melanoma: Challenges for BRAF mutation detection

Chen, G., Dudley, J., Tseng, L. H., Smith, K., Gurda, G. T., Gocke, C. D., Eshleman, J. R. & Lin, M. T., Jan 1 2015, In : Human pathology. 46, 1, p. 113-119 7 p.

Research output: Contribution to journalArticle

Mutational profiling of colorectal cancers with microsatellite instability

Lin, E. I., Tseng, L. H., Gocke, C. D., Reil, S., Le, D. T., Azad, N. S. & Eshleman, J. R., Jan 1 2015, In : Oncotarget. 6, 39, p. 42334-42344 11 p.

Research output: Contribution to journalArticle

Non-p.V600E BRAF mutations are common using a more sensitive and broad detection tool

Carter, J., Tseng, L. H., Zheng, G., Dudley, J., Illei, P., Gocke, C. D., Eshleman, J. R. & Lin, M. T., Oct 2015, In : American journal of clinical pathology. 144, 4, p. 620-628 9 p.

Research output: Contribution to journalArticle

PD-1 blockade in tumors with mismatch-repair deficiency

Le, D. T., Uram, J. N., Wang, H., Bartlett, B. R., Kemberling, H., Eyring, A. D., Skora, A. D., Luber, B. S., Azad, N. S., Laheru, D., Biedrzycki, B., Donehower, R. C., Zaheer, A., Fisher, G. A., Crocenzi, T. S., Lee, J. J., Duffy, S. M., Goldberg, R. M., De La Chapelle, A., Koshiji, M. & 15 others, Bhaijee, F., Huebner, T., Hruban, R. H., Wood, L. D., Cuka, N., Pardoll, D. M., Papadopoulos, N., Kinzler, K. W., Zhou, S., Cornish, T. C., Taube, J. M., Anders, R. A., Eshleman, J. R., Vogelstein, B. & Diaz, L. A., Jun 25 2015, In : New England Journal of Medicine. 372, 26, p. 2509-2520 12 p.

Research output: Contribution to journalArticle

PD-L1 expression in melanocytic lesions does not correlate with the BRAF V600E mutation

Rodic, N., Anders, R. A., Eshleman, J. R., Lin, M. T., Xu, H., Kim, J. H., Beierl, K., Chen, S., Luber, B. S., Wang, H., LTopalian, S., Pardoll, D. M. & Taube, J. M., Feb 2015, In : Cancer Immunology Research. 3, 2, p. 110-115 6 p.

Research output: Contribution to journalArticle

Performance characteristics of next-generation sequencing in clinical mutation detection of colorectal cancers

Haley, L., Tseng, L. H., Zheng, G., Dudley, J., Anderson, D. A., Azad, N. S., Gocke, C. D., Eshleman, J. R. & Lin, M. T., Oct 3 2015, In : Modern Pathology. 28, 10, p. 1390-1399 10 p.

Research output: Contribution to journalArticle

Software-based pyrogram® evaluation

Chen, G., Olson, M. T. & Eshleman, J. R., Jan 1 2015, In : Methods in Molecular Biology. 1315, p. 29-38 10 p.

Research output: Contribution to journalArticle

Transflip mutations produce deletions in pancreatic cancer

Norris, A. L., Kamiyama, H., Makohon-Moore, A., Pallavajjala, A., Morsberger, L. A., Lee, K., Batista, D., Iacobuzio-Donahue, C. A., Lin, M. T., Klein, A. P., Hruban, R. H., Wheelan, S. J. & Eshleman, J. R., Aug 1 2015, In : Genes Chromosomes and Cancer. 54, 8, p. 472-481 10 p.

Research output: Contribution to journalArticle

Whole genomes redefine the mutational landscape of pancreatic cancer

Waddell, N., Pajic, M., Patch, A. M., Chang, D. K., Kassahn, K. S., Bailey, P., Johns, A. L., Miller, D., Nones, K., Quek, K., Quinn, M. C. J., Robertson, A. J., Fadlullah, M. Z. H., Bruxner, T. J. C., Christ, A. N., Harliwong, I., Idrisoglu, S., Manning, S., Nourse, C., Nourbakhsh, E. & 69 others, Wani, S., Wilson, P. J., Markham, E., Cloonan, N., Anderson, M. J., Fink, J. L., Holmes, O., Kazakoff, S. H., Leonard, C., Newell, F., Poudel, B., Song, S., Taylor, D., Waddell, N., Wood, S., Xu, Q., Wu, J., Pinese, M., Cowley, M. J., Lee, H. C., Jones, M. D., Nagrial, A. M., Humphris, J., Chantrill, L. A., Chin, V., Steinmann, A. M., Mawson, A., Humphrey, E. S., Colvin, E. K., Chou, A., Scarlett, C. J., Pinho, A. V., Giry-Laterriere, M., Rooman, I., Samra, J. S., Kench, J. G., Pettitt, J. A., Merrett, N. D., Toon, C., Epari, K., Nguyen, N. Q., Barbour, A., Zeps, N., Jamieson, N. B., Graham, J. S., Niclou, S. P., Bjerkvig, R., Grützmann, R., Aust, D., Hruban, R. H., Maitra, A., Iacobuzio-Donahue, C., Wolfgang, C. L., Morgan, R. A., Lawlor, R. T., Corbo, V., Bassi, C., Falconi, M., Zamboni, G., Tortora, G., Tempero, M. A., Gill, A. J., Eshleman, J. R., Pilarsky, C., Scarpa, A., Musgrove, E. A., Pearson, J. V., Biankin, A. V. & Grimmond, S. M., Feb 26 2015, In : Nature. 518, 7540, p. 495-501 7 p.

Research output: Contribution to journalArticle

2014

Advancements in the development of hif-1a-activated protein switches for use in enzyme prodrug therapy e114032

Wright, R. C., Khakhar, A., Eshleman, J. R. & Ostermeier, M., Nov 26 2014, In : PloS one. 9, 11, 014032.

Research output: Contribution to journalArticle

BRAF pyrosequencing analysis aided by a lookup table

Olson, M. T., Harrington, C., Beierl, K., Chen, G., Thiess, M., O'Neill, A., Taube, J. M., Zeiger, M. A., Lin, M. T. & Eshleman, J. R., May 1 2014, In : American journal of clinical pathology. 141, 5, p. 639-647 9 p.

Research output: Contribution to journalArticle

Clinical validation of KRAS, BRAF, and EGFR mutation detection using next-generation sequencing

Lin, M. T., Mosier, S. L., Thiess, M., Beierl, K. F., Debeljak, M., Tseng, L. H., Chen, G., Yegnasubramanian, S., Ho, H., Cope, L., Wheelan, S. J., Gocke, C. D. & Eshleman, J. R., Jun 2014, In : American journal of clinical pathology. 141, 6, p. 856-866 11 p.

Research output: Contribution to journalArticle

Cytosine Deamination Is a Major Cause of Baseline Noise in Next-Generation Sequencing

Chen, G., Mosier, S., Gocke, C. D., Lin, M. T. & Eshleman, J. R., Oct 1 2014, In : Molecular Diagnosis and Therapy. 18, 5, p. 587-593 7 p.

Research output: Contribution to journalArticle

DNA mismatch repair defects and microsatellite instability status in periocular sebaceous carcinoma

Rajan Kd, A., Burris, C., Iliff, N., Grant, M., Eshleman, J. R. & Eberhart, C. G., Mar 2014, In : American journal of ophthalmology. 157, 3, p. 640-647.e2

Research output: Contribution to journalArticle

False positives in multiplex PCR-based next-generation sequencing have unique signatures

McCall, C. M., Mosier, S., Thiess, M., Debeljak, M., Pallavajjala, A., Beierl, K., Deak, K. L., Datto, M. B., Gocke, C. D., Lin, M. T. & Eshleman, J. R., Sep 2014, In : Journal of Molecular Diagnostics. 16, 5, p. 541-549 9 p.

Research output: Contribution to journalArticle

Haplotype counting by next-generation sequencing for ultrasensitive human DNA detection

Debeljak, M., Freed, D. N., Welch, J. A., Haley, L., Beierl, K., Iglehart, B. S., Pallavajjala, A., Gocke, C. D., Leffell, M. S., Lin, M. T., Pevsner, J., Wheelan, S. J. & Eshleman, J. R., Sep 2014, In : Journal of Molecular Diagnostics. 16, 5, p. 495-503 9 p.

Research output: Contribution to journalArticle

Improved FLT3 Internal Tandem Duplication PCR Assay Predicts Outcome after Allogeneic Transplant for Acute Myeloid Leukemia

Grunwald, M. R., Tseng, L. H., Lin, M. T., Pratz, K. W., Eshleman, J. R., Levis, M. J. & Gocke, C. D., Dec 1 2014, In : Biology of Blood and Marrow Transplantation. 20, 12, p. 1989-1995 7 p.

Research output: Contribution to journalArticle

Microsatellite instability confounds engraftment analysis of hematopoietic stem-cell transplantation

Tseng, L. H., Tang, J. L., Haley, L., Beierl, K., Gocke, C. D., Eshleman, J. R. & Lin, M. T., Jul 2014, In : Applied Immunohistochemistry and Molecular Morphology. 22, 6, p. 416-420 5 p.

Research output: Contribution to journalReview article

Tumor cellularity as a quality assurance measure for accurate clinical detection of braf mutations in melanoma

Dudley, J. C., Gurda, G. T., Tseng, L. H., Anderson, D. A., Chen, G., Taube, J. M., Gocke, C. D., Eshleman, J. R. & Lin, M. T., Aug 2014, In : Molecular Diagnosis and Therapy. 18, 4, p. 409-418 10 p.

Research output: Contribution to journalArticle

Whole-exome sequencing of pancreatic neoplasms with acinar differentiation

Jiao, Y., Yonescu, R., Offerhaus, G. J. A., Klimstra, D. S., Maitra, A., Eshleman, J. R., Herman, J. G., Poh, W., Pelosof, L., Wolfgang, C. L., Vogelstein, B., Kinzler, K. W., Hruban, R. H., Papadopoulos, N. & Wood, L. D., Mar 1 2014, In : Journal of Pathology. 232, 4, p. 428-435 8 p.

Research output: Contribution to journalArticle

2013

Clinicopathological correlates of activating gnas mutations in intraductal papillary mucinous neoplasm (IPMN) of the pancreas

Dal Molin, M., Matthaei, H., Wu, J., Blackford, A., Debeljak, M., Rezaee, N., Wolfgang, C. L., Butturini, G., Salvia, R., Bassi, C., Goggins, M. G., Kinzler, K. W., Vogelstein, B., Eshleman, J. R., Hruban, R. H. & Maitra, A., Nov 1 2013, In : Annals of Surgical Oncology. 20, 12, p. 3802-3808 7 p.

Research output: Contribution to journalArticle

Detection of minor clones with internal tandem duplication mutations of FLT3 gene in acute myeloid leukemia using delta-PCR

Beierl, K., Tseng, L. H., Beierl, R., Haley, L., Gocke, C. D., Eshleman, J. R. & Lin, M. T., Mar 1 2013, In : Diagnostic Molecular Pathology. 22, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Does BRAF V600e mutation predict aggressive features in papillary thyroid cancer? results from four endocrine surgery centers

Li, C., Aragon Han, P., Lee, K. C., Lee, L. C., Fox, A. C., Beninato, T., Thiess, M., Dy, B. M., Sebo, T. J., Thompson, G. B., Grant, C. S., Giordano, T. J., Gauger, P. G., Doherty, G. M., Fahey, T. J., Bishop, J., Eshleman, J. R., Umbricht, C. B., Schneider, E. B. & Zeiger, M. A., Sep 1 2013, In : Journal of Clinical Endocrinology and Metabolism. 98, 9, p. 3702-3712 11 p.

Research output: Contribution to journalArticle

Evaluation of DNA from the papanicolaou test to detect ovarian and endometrial cancers

Kinde, I., Bettegowda, C., Wang, Y., Wu, J., Agrawal, N., Shih, I. M., Kurman, R., Dao, F., Levine, D. A., Giuntoli, R., Roden, R., Eshleman, J. R., Carvalho, J. P., Marie, S. K. N., Papadopoulos, N., Kinzler, K. W., Vogelstein, B. & Diaz, L. A., Jan 9 2013, In : Science translational medicine. 5, 167, 167ra4.

Research output: Contribution to journalArticle

Fundamentals of pyrosequencing

Harrington, C. T., Lin, E. I., Olson, M. T. & Eshleman, J. R., Sep 1 2013, In : Archives of Pathology and Laboratory Medicine. 137, 9, p. 1296-1303 8 p.

Research output: Contribution to journalReview article

Mutant GNAS detected in duodenal collections of secretin-stimulated pancreatic juice indicates the presence or emergence of pancreatic cysts

Kanda, M., Knight, S., Topazian, M., Syngal, S., Farrell, J., Lee, J., Kamel, I., Lennon, A. M., Borges, M., Young, A., Fujiwara, S., Seike, J., Eshleman, J., Hruban, R. H., Canto, M. I. & Goggins, M., Jul 1 2013, In : Gut. 62, 7, p. 1024-1033 10 p.

Research output: Contribution to journalArticle

Personalized chemotherapy profiling using cancer cell lines from selectable mice

Kamiyama, H., Rauenzahn, S., Shim, J. S., Karikari, C. A., Feldmann, G., Hua, L., Kamiyama, M., Schuler, F. W., Lin, M. T., Beaty, R. M., Karanam, B., Liang, H., Mullendore, M. E., Mo, G., Hidalgo, M., Jaffee, E., Hruban, R. H., Jinnah, H. A., Roden, R. B. S., Jimeno, A. & 3 others, Liu, J. O., Maitra, A. & Eshleman, J. R., Mar 1 2013, In : Clinical Cancer Research. 19, 5, p. 1139-1146 8 p.

Research output: Contribution to journalArticle

Tandem duplication PCR: An ultrasensitive assay for the detection of internal tandem duplications of the FLT3 Gene

Lin, M. T., Tseng, L. H., Beierl, K., Hsieh, A., Thiess, M., Chase, N., Stafford, A., Levis, M. J., Eshleman, J. R. & Gocke, C. D., Sep 1 2013, In : Diagnostic Molecular Pathology. 22, 3, p. 149-155 7 p.

Research output: Contribution to journalArticle

The frequency of KRAS and BRAF mutations in intrahepatic cholangiocarcinomas and their correlation with clinical outcome

Robertson, S., Hyder, O., Dodson, R., Nayar, S. K., Poling, J., Beierl, K., Eshleman, J. R., Lin, M. T., Pawlik, T. M. & Anders, R. A., Dec 1 2013, In : Human pathology. 44, 12, p. 2768-2773 6 p.

Research output: Contribution to journalArticle

2012

Analysis of polymorphisms and haplotype structure of the human thymidylate synthase genetic region: A tool for pharmacogenetic studies

Ghosh, S., Hossain, M. Z., Borges, M., Goggins, M. G., Ingersoll, R. G., Eshleman, J. R., Klein, A. P. & Kern, S. E., Apr 5 2012, In : PloS one. 7, 4, e34426.

Research output: Contribution to journalArticle

ATM mutations in patients with hereditary pancreatic cancer

Roberts, N. J., Jiao, Y., Yu, J., Kopelovich, L., Petersen, G. M., Bondy, M. L., Gallinger, S., Schwartz, A. G., Syngal, S., Cote, M. L., Axilbund, J., Schulick, R., Ali, S. Z., Eshleman, J. R., Velculescu, V. E., Goggins, M., Vogelstein, B., Papadopoulos, N., Hruban, R. H., Kinzler, K. W. & 1 others, Klein, A. P., Jan 1 2012, In : Cancer discovery. 2, 1, p. 41-46 6 p.

Research output: Contribution to journalArticle

A virtual pyrogram generator to resolve complex pyrosequencing results

Chen, G., Olson, M. T., O'Neill, A., Norris, A., Beierl, K., Harada, S., Debeljak, M., Rivera-Roman, K., Finley, S., Stafford, A., Gocke, C. D., Lin, M. T. & Eshleman, J. R., Mar 1 2012, In : Journal of Molecular Diagnostics. 14, 2, p. 149-159 11 p.

Research output: Contribution to journalArticle

Clinicopathological characteristics and molecular analyses of multifocal intraductal papillary mucinous neoplasms of the pancreas

Matthaei, H., Norris, A. L., Tsiatis, A. C., Olino, K., Hong, S. M., Dal Molin, M., Goggins, M. G., Canto, M., Horton, K. M., Jackson, K. D., Capelli, P., Zamboni, G., Bortesi, L., Furukawa, T., Egawa, S., Ishida, M., Ottomo, S., Unno, M., Motoi, F., Wolfgang, C. L. & 6 others, Edil, B. H., Cameron, J. L., Eshleman, J. R., Schulick, R. D., Maitra, A. & Hruban, R. H., Feb 1 2012, In : Annals of surgery. 255, 2, p. 326-333 8 p.

Research output: Contribution to journalArticle

Genetically defined subsets of human pancreatic cancer show unique in vitro chemosensitivity

Cui, Y., Brosnan, J. A., Blackford, A. L., Sur, S., Hruban, R. H., Kinzler, K. W., Vogelstein, B., Maitra, A., Diaz, L. A., Iacobuzio-Donahue, C. A. & Eshleman, J. R., Dec 1 2012, In : Clinical Cancer Research. 18, 23, p. 6519-6530 12 p.

Research output: Contribution to journalArticle

GNAS codon 201 mutations are uncommon in intraductal papillary neoplasms of the bile duct

Matthaei, H., Wu, J., Dal Molin, M., Debeljak, M., Lingohr, P., Katabi, N., Klimstra, D. S., Adsay, N. V., Eshleman, J. R., Schulick, R. D., Kinzler, K. W., Vogelstein, B., Hruban, R. H. & Maitra, A., Oct 2012, In : HPB. 14, 10, p. 677-683 7 p.

Research output: Contribution to journalArticle

Loss of expression of the SWI/SNF chromatin remodeling subunit BRG1/SMARCA4 is frequently observed in intraductal papillary mucinous neoplasms of the pancreas

Dal Molin, M., Hong, S. M., Hebbar, S., Sharma, R., Scrimieri, F., De Wilde, R. F., Mayo, S. C., Goggins, M., Wolfgang, C. L., Schulick, R. D., Lin, M. T., Eshleman, J. R., Hruban, R. H., Maitra, A. & Matthaei, H., Apr 1 2012, In : Human pathology. 43, 4, p. 585-591 7 p.

Research output: Contribution to journalArticle

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

Biankin, A. V., Waddell, N., Kassahn, K. S., Gingras, M. C., Muthuswamy, L. B., Johns, A. L., Miller, D. K., Wilson, P. J., Patch, A. M., Wu, J., Chang, D. K., Cowley, M. J., Gardiner, B. B., Song, S., Harliwong, I., Idrisoglu, S., Nourse, C., Nourbakhsh, E., Manning, S., Wani, S. & 106 others, Gongora, M., Pajic, M., Scarlett, C. J., Gill, A. J., Pinho, A. V., Rooman, I., Anderson, M., Holmes, O., Leonard, C., Taylor, D., Wood, S., Xu, Q., Nones, K., Fink, J. L., Christ, A., Bruxner, T., Cloonan, N., Kolle, G., Newell, F., Pinese, M., Mead, R. S., Humphris, J. L., Kaplan, W., Jones, M. D., Colvin, E. K., Nagrial, A. M., Humphrey, E. S., Chou, A., Chin, V. T., Chantrill, L. A., Mawson, A., Samra, J. S., Kench, J. G., Lovell, J. A., Daly, R. J., Merrett, N. D., Toon, C., Epari, K., Nguyen, N. Q., Barbour, A., Zeps, N., Kakkar, N., Zhao, F., Wu, Y. Q., Wang, M., Muzny, D. M., Fisher, W. E., Brunicardi, F. C., Hodges, S. E., Reid, J. G., Drummond, J., Chang, K., Han, Y., Lewis, L. R., Dinh, H., Buhay, C. J., Beck, T., Timms, L., Sam, M., Begley, K., Brown, A., Pai, D., Panchal, A., Buchner, N., De Borja, R., Denroche, R. E., Yung, C. K., Serra, S., Onetto, N., Mukhopadhyay, D., Tsao, M. S., Shaw, P. A., Petersen, G. M., Gallinger, S., Hruban, R. H., Maitra, A., Iacobuzio-Donahue, C. A., Schulick, R. D., Wolfgang, C. L., Morgan, R. A., Lawlor, R. T., Capelli, P., Corbo, V., Scardoni, M., Tortora, G., Tempero, M. A., Mann, K. M., Jenkins, N. A., Perez-Mancera, P. A., Adams, D. J., Largaespada, D. A., Wessels, L. F. A., Rust, A. G., Stein, L. D., Tuveson, D. A., Copeland, N. G., Musgrove, E. A., Scarpa, A., Eshleman, J. R., Hudson, T. J., Sutherland, R. L., Wheeler, D. A., Pearson, J. V., McPherson, J. D., Gibbs, R. A. & Grimmond, S. M., Nov 15 2012, In : Nature. 491, 7424, p. 399-405 7 p.

Research output: Contribution to journalArticle

Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types

Jones, S., Li, M., Williams Parsons, D., Zhang, X., Wesseling, J., Kristel, P., Schmidt, M. K., Markowitz, S., Yan, H., Bigner, D., Hruban, R. H., Eshleman, J. R., Iacobuzio-Donahue, C. A., Goggins, M., Maitra, A., Malek, S. N., Powell, S., Vogelstein, B., Kinzler, K. W., Velculescu, V. E. & 1 others, Papadopoulos, N., Jan 1 2012, In : Human mutation. 33, 1, p. 100-103 4 p.

Research output: Contribution to journalArticle

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma

Pérez-Mancera, P. A., Rust, A. G., Van Der Weyden, L., Kristiansen, G., Li, A., Sarver, A. L., Silverstein, K. A. T., Grützmann, R., Aust, D., Rümmele, P., Knösel, T., Herd, C., Stemple, D. L., Kettleborough, R., Brosnan, J. A., Li, A., Morgan, R., Knight, S., Yu, J., Stegeman, S. & 135 others, Collier, L. S., Ten Hoeve, J. J., De Ridder, J., Klein, A. P., Goggins, M., Hruban, R. H., Chang, D. K., Biankin, A. V. W., Grimmond, S. M., Wessels, L. F. A., Wood, S. A., Iacobuzio-Donahue, C. A., Pilarsky, C., Largaespada, D. A., Adams, D. J., Tuveson, D. A., Bienkin, A. V., Johns, A. L., Mawson, A., Cheng, D. K., Brancato, M. A. L., Rowe, S. J., Simpson, S. L., Martyn-Smith, M., Chantrill, L. A., Chin, V. T., Chou, A., Cowley, M. J., Humphris, J. L., Jones, M. D., Scott Mead, R., Nagrial, A. M., Pajic, M., Pettit, J., Pinese, M., Rooman, I., Wu, J., Daly, R. J., Musgrove, E. A., Sutherland, R. L., Grimond, S. M., Waddell, N., Kassahn, K. S., Miller, D. K., Wilson, P. J., Patch, A. M., Song, S., Harliwong, I., Idrisoglu, S., Nourse, C., Nourbakhsh, E., Manning, S., Wani, S., Gongora, M., Anderson, M., Holmes, O., Leonard, C., Taylor, D., Wood, S., Xu, C., Nones, K., Lynn Fink, J., Christ, A., Bruxner, T., Cloonan, N., Newell, F., Pearson, J. V., Samra, J. S., Gill, A. J., Pavlakis, N., Guminski, A., Toon, C., Blankin, A. V., Asghari, R., Merrett, N. D., Pavey, D. A., Das, A., Cosman, P. H., Ismail, K., O'Connor, C., Lam, V. W., McLeod, D., Pleass, H. C., James, V., Kench, J. G., Cooper, C. L., Joseph, D., Sandroussi, C., Crawford, M., Texler, M., Forrest, C., Laycock, A., Epari, K. P., Ballal, M., Fletcher, D. R., Mukhedkar, S., Spry, N. A., Deboer, B., Chai, M., Feeney, K., Zeps, N., Beilin, M., Nguyen, N. Q., Ruszkiewicz, A. R., Worthley, C., Tan, C. P., Debrencini, T., Chen, J., Brooke-Smith, M. E., Papangelis, V., Tang, H., Barbour, A. P., Clouston, A. D., Martin, P., O'Rourke, T. J., Chiang, A., Fawcett, J. W., Slater, K., Yeung, S., Hatzifotis, M., Hodgkinson, P., Christophi, C., Nikfarjam, M., Cancer Biobank, V., Eshleman, J. R., Maitra, A., Schulick, R. D., Wolfgang, C. L., Morgan, R. A., Lawlor, R. T., Beghelli, S., Corbo, V., Scardoni, M., Bassi, C. & Tempero, M. A., Jun 14 2012, In : Nature. 486, 7402, p. 266-270 5 p.

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2011

Analysis of hematopoietic stem cell transplant engraftment: Use of loss or gain of microsatellite alleles to identify residual hematopoietic malignancy

Lin, M. T., Tseng, L. H., Beierl, K., Harada, S., Hafez, M. J., Eshleman, J. R. & Gocke, C. D., Dec 1 2011, In : Diagnostic Molecular Pathology. 20, 4, p. 194-202 9 p.

Research output: Contribution to journalArticle

A protein therapeutic modality founded on molecular regulation

Wright, C. M., Wright, R. C., Eshleman, J. R. & Ostermeier, M., Sep 27 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 39, p. 16206-16211 6 p.

Research output: Contribution to journalArticle