Irina Burd

Associate Professor

19992020

Research output per year

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Research Output

2020

Characterization of an Adapted Murine Model of Intrauterine Inflammation–Induced Preterm Birth

Zierden, H. C., Ortiz Ortiz, J. I., Dimitrion, P., Laney, V., Bensouda, S., Anders, N. M., Scardina, M., Hoang, T., Ronnett, B. M., Hanes, J., Burd, I., Mahendroo, M. & Ensign, L. M., Feb 2020, In : American Journal of Pathology. 190, 2, p. 295-305 11 p.

Research output: Contribution to journalArticle

Correction: In Utero Exposure to Citalopram Mitigates Maternal Stress Effects on Fetal Brain Development (ACS Chem. Neurosci. (2019) 10:7 (3307−3317) DOI: 10.1021/acschemneuro.9b00180)

Velasquez, J. C., Zhao, Q., Chan, Y., Galindo, L. C. M., Simasotchi, C., Wu, D., Hou, Z., Herod, S. M., Oberlander, T. F., Gil, S., Fournier, T., Burd, I., Andrews, A. M. & Bonnin, A., Feb 5 2020, In : ACS Chemical Neuroscience. 11, 3, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Diffusion MRI revealed altered inter-hippocampal projections in the mouse brain after intrauterine inflammation

Wu, D., Lei, J., Xie, H., Dong, J. & Burd, I., Apr 1 2020, In : Brain Imaging and Behavior. 14, 2, p. 383-395 13 p.

Research output: Contribution to journalArticle

Mouse Bone Marrow-Derived Mesenchymal Stem Cells Alleviate Perinatal Brain Injury Via a CD8+ T Cell Mechanism in a Model of Intrauterine Inflammation

Zhao, H., Xie, L., Clemens, J. L., Zong, L., McLane, M. W., Arif, H., Feller, M. C., Jia, B., Zhu, Y., Facciabene, A., Ozen, M., Lei, J. & Burd, I., Jan 1 2020, (Accepted/In press) In : Reproductive Sciences.

Research output: Contribution to journalArticle

The orphan nuclear receptor Nr4a1 mediates perinatal neuroinflammation in a murine model of preterm labor

Estrada, S. M., Thagard, A. S., Dehart, M. J., Damicis, J. R., Dornisch, E. M., Ippolito, D. L., Burd, I., Napolitano, P. G. & Ieronimakis, N., Jan 1 2020, In : Cell Death and Disease. 11, 1, 11.

Research output: Contribution to journalArticle

Open Access
2019

Administration of melatonin for prevention of preterm birth and fetal brain injury associated with premature birth in a mouse model

Lee, J. Y., Song, H., Dash, O., Park, M., Shin, N. E., McLane, M. W., Lei, J., Hwang, J. Y. & Burd, I., Jan 1 2019, In : American Journal of Reproductive Immunology. e13151.

Research output: Contribution to journalArticle

Exposure to systemic and intrauterine inflammation leads to decreased pup survival via different placental mechanisms

Lee, J. Y., Shin, N. E., Na, Q., Dong, J., Chudnovets, A., Li, S., Novak, C., McLane, M. W., Lei, J. & Burd, I., Jun 1 2019, In : Journal of Reproductive Immunology. 133, p. 52-62 11 p.

Research output: Contribution to journalArticle

IL-1 receptor antagonist therapy mitigates placental dysfunction and perinatal injury following Zika virus infection

Lei, J., Vermillion, M. S., Jia, B., Xie, H., Xie, L., McLane, M. W., Sheffield, J. S., Pekosz, A., Brown, A., Klein, S. L. & Burd, I., Jan 1 2019, In : JCI Insight. 4, 7, e122678.

Research output: Contribution to journalArticle

Open Access

In utero exposure to citalopram mitigates maternal stress effects on fetal brain development

Velasquez, J. C., Zhao, Q., Chan, Y., Galindo, L. C. M., Simasotchi, C., Wu, D., Hou, Z., Herod, S. M., Oberlander, T. F., Gil, S., Fournier, T., Burd, I., Andrews, A. M. & Bonnin, A., Jul 17 2019, In : ACS Chemical Neuroscience. 10, 7, p. 3307-3317 11 p.

Research output: Contribution to journalArticle

Magnesium sulfate inhibits inflammation through P2X7 receptors in human umbilical vein endothelial cells

Ozen, M., Xie, H., Shin, N., Al Yousif, G., Clemens, J., McLane, M. W., Lei, J. & Burd, I., Jan 1 2019, (Accepted/In press) In : Pediatric research.

Research output: Contribution to journalArticle

Maternal inflammation leads to different mTORC1 activity varied by anatomic locations in mouse placenta

Dong, J., Shin, N., Lee, J. Y., Jia, B., Chudnovets, A., Mclane, M. W., Li, S., Na, Q., Lei, J. & Burd, I., Nov 21 2019, In : Biology of reproduction. 101, 5, p. 1046-1055 10 p.

Research output: Contribution to journalArticle

Open Access

Maternal Supplementation of Low Dose Fluoride Alleviates Adverse Perinatal Outcomes Following Exposure to Intrauterine Inflammation

Jia, B., Zong, L., Lee, J. Y., Lei, J., Zhu, Y., Xie, H., Clemens, J. L., Feller, M. C., Na, Q., Dong, J., McLane, M. W., Jones-Beatty, K. & Burd, I., Dec 1 2019, In : Scientific reports. 9, 1, 2575.

Research output: Contribution to journalArticle

Open Access

Melatonin for prevention of placental malperfusion and fetal compromise associated with intrauterine inflammation-induced oxidative stress in a mouse model

Lee, J. Y., Li, S., Shin, N. E., Na, Q., Dong, J., Jia, B., Jones-Beatty, K., McLane, M. W., Ozen, M., Lei, J. & Burd, I., Jan 1 2019, In : Journal of pineal research. e12591.

Research output: Contribution to journalArticle

Placental malperfusion in response to intrauterine inflammation and its connection to fetal sequelae

Eloundou, S. N., Lee, J. Y., Wu, D., Lei, J., Feller, M. C., Ozen, M., Zhu, Y., Hwang, M., Jia, B., Xie, H., Clemens, J. L., McLane, M. W., AlSaggaf, S., Nair, N., Wills-Karp, M., Wang, X., Graham, E. M., Baschat, A. & Burd, I., Apr 1 2019, In : PloS one. 14, 4, e0214951.

Research output: Contribution to journalArticle

Open Access

Preterm birth subtypes, placental pathology findings, and risk of neurodevelopmental disabilities during childhood

Raghavan, R., Helfrich, B. B., Cerda, S. R., Ji, Y., Burd, I., Wang, G., Hong, X., Fu, L., Pearson, C., Daniele Fallin, M., Zuckerman, B. & Wang, X., Aug 1 2019, In : Placenta. 83, p. 17-25 9 p.

Research output: Contribution to journalArticle

The fetal origins of mental illness

al-Haddad, B. J. S., Oler, E., Armistead, B., Elsayed, N. A., Weinberger, D. R., Bernier, R., Burd, I., Kapur, R., Jacobsson, B., Wang, C., Mysorekar, I., Rajagopal, L. & Adams Waldorf, K. M., Dec 2019, In : American journal of obstetrics and gynecology. 221, 6, p. 549-562 14 p.

Research output: Contribution to journalReview article

2018

Antenatal prevention of cerebral palsy and childhood disability: Is the impossible possible?

Ellery, S. J., Kelleher, M., Grigsby, P., Burd, I., Derks, J. B., Hirst, J., Miller, S. L., Sherman, L. S., Tolcos, M. & Walker, D. W., Jan 1 2018, (Accepted/In press) In : Journal of Physiology.

Research output: Contribution to journalArticle

A prospective birth cohort study on maternal cholesterol levels and offspring attention deficit hyperactivity disorder: New insight on sex differences

Ji, Y., Riley, A. W., Lee, L-C., Volk, H., Hong, X., Wang, G., Angomas, R., Stivers, T., Wahl, A., Ji, H. K., Bartell, T. R., Burd, I., Paige, D. M., Fallin, D. D., Zuckerman, B. & Wang, X., Jan 1 2018, In : Brain Sciences. 8, 1, 3.

Research output: Contribution to journalArticle

Dynamic glucose enhanced MRI of the placenta in a mouse model of intrauterine inflammation

Wu, D., Xu, J., Lei, J., Mclane, M., Van Zijl, P. C. & Burd, I., Sep 1 2018, In : Placenta. 69, p. 86-91 6 p.

Research output: Contribution to journalArticle

Editorial: Prenatal beginnings for better health

Kim, E., Costantine, M., Baschat, A. & Burd, I., May 4 2018, In : Frontiers in Pharmacology. 9, MAY, 457.

Research output: Contribution to journalEditorial

Genome-wide DNA methylation associations with spontaneous preterm birth in US blacks: findings in maternal and cord blood samples

Hong, X., Sherwood, B., Ladd-Acosta, C. M., Peng, S., Ji, H. K., Hao, K., Burd, I., Bartell, T. R., Wang, G., Tsai, H. J., Liu, X., Ji, Y., Wahl, A., Caruso, D., Lee-Parritz, A., Zuckerman, B. & Wang, X., Mar 1 2018, (Accepted/In press) In : Epigenetics. p. 1-10 10 p.

Research output: Contribution to journalArticle

Heme oxygenase-1 deficiency results in splenic T-cell dysregulation in offspring of mothers exposed to late gestational inflammation

Ozen, M., Zhao, H., Kalish, F., Yang, Y., Folkins, A., Burd, I., Wong, R. J. & Stevenson, D. K., Jan 1 2018, (Accepted/In press) In : American Journal of Reproductive Immunology.

Research output: Contribution to journalArticle

Immunoperinatology

Ozen, M. & Burd, I., May 1 2018, In : American Journal of Reproductive Immunology. 79, 5, e12847.

Research output: Contribution to journalEditorial

Increased placental T cell trafficking results in adverse neurobehavioral outcomes in offspring exposed to sub-chronic maternal inflammation

Novak, C., Lee, J. Y., Ozen, M., Tsimis, M. E., Kucirka, L. M., McLane, M. W., Xie, L., Kelleher, M., Xie, H., Jia, B., Lei, J. & Burd, I., Jan 1 2018, (Accepted/In press) In : Brain, Behavior, and Immunity.

Research output: Contribution to journalArticle

Journey to the center of the fetal brain: Environmental exposures and autophagy

Lei, J., Calvo, P., Vigh, R. & Burd, I., May 3 2018, In : Frontiers in Cellular Neuroscience. 12, 118.

Research output: Contribution to journalReview article

Maternal biomarkers of acetaminophen use and offspring attention deficit hyperactivity disorder

Ji, Y., Riley, A. W., Lee, L-C., Hong, X., Wang, G., Tsai, H. J., Mueller, N., Pearson, C., Thermitus, J., Panjwani, A., Ji, H. K., Bartell, T. R., Burd, I., Fallin, D. D. & Wang, X., Jul 1 2018, In : Brain Sciences. 8, 7, 127.

Research output: Contribution to journalArticle

Maternal Glucose Supplementation in a Murine Model of Chorioamnionitis Alleviates Dysregulation of Autophagy in Fetal Brain

Lei, J., Zhong, W., Almalki, A., Zhao, H., Arif, H., Rozzah, R., Al Yousif, G., Alhejaily, N., Wu, D., McLane, M. & Burd, I., Aug 1 2018, In : Reproductive Sciences. 25, 8, p. 1175-1185 11 p.

Research output: Contribution to journalArticle

Mice deficient in AKAP13 (BRX) develop compulsive-like behavior and increased body weight

Maravet Baig, K., Su, S. C., Mumford, S. L., Giuliani, E., Ng, S. S. M., Armstrong, C., Keil, M. F., Vaught, K. C., Olsen, N., Pettiford, E., Burd, I. & Segars, J., Jun 1 2018, In : Brain Research Bulletin. 140, p. 72-79 8 p.

Research output: Contribution to journalArticle

Perinatal Brain Injury: Mechanisms, Prevention, and Outcomes

Novak, C., Ozen, M. & Burd, I., Jan 1 2018, (Accepted/In press) In : Clinics in Perinatology.

Research output: Contribution to journalArticle

Placenta immune infiltrates and perinatal outcomes

Ozen, M., Novak, C. & Burd, I., Jan 1 2018, (Accepted/In press) In : American Journal of Reproductive Immunology.

Research output: Contribution to journalArticle

2017

Advanced Pediatric Neurosonography Techniques: Contrast-Enhanced Ultrasonography, Elastography, and Beyond

Hwang, M., Riggs, B. J., Katz, J., Seyfert, D., Northington, F., Robinson, S., Burd, I., McArthur, J. C., Darge, K., Thimm, M. A. & Huisman, T. A. G. M., Jan 1 2017, (Accepted/In press) In : Journal of Neuroimaging.

Research output: Contribution to journalArticle

Bacterial endotoxin exposure invokes transcriptional changes in embryonic murine neural stem cells

Ieronimakis, N., Estrada, S. M., Thagard, A. S., Napolitano, P. G., Lane, A. D., Dehart, M. J. & Burd, I., 2017, (Accepted/In press) In : American Journal of Obstetrics and Gynecology.

Research output: Contribution to journalArticle

Effect of maternal obesity on Maternal-Fetal transfer of preoperative cefazolin at cesarean section

Groff, S. M., Fallatah, W., Yang, S., Murphy, J., Crutchfield, C., Marzinke, M. A., Kurtzberg, J., Lee, C. K., Burd, I. & Azadeh, F., May 1 2017, In : Journal of Pediatric Pharmacology and Therapeutics. 22, 3, p. 227-232 6 p.

Research output: Contribution to journalArticle

Functional changes in hippocampal synaptic signaling in offspring survivors of a mouse model of intrauterine inflammation

Kelley, M. H., Wu, W. W., Lei, J., McLane, M., Xie, H., Hart, K. D., Pereira, L., Burd, I. & Maylie, J., Sep 5 2017, In : Journal of Neuroinflammation. 14, 1, 180.

Research output: Contribution to journalArticle

Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth

Hong, X., Hao, K., Ji, H., Peng, S., Sherwood, B., Di Narzo, A., Tsai, H. J., Liu, X., Burd, I., Wang, G., Ji, Y., Caruso, D., Mao, G., Bartell, T. R., Zhang, Z., Pearson, C., Heffner, L., Cerda, S., Beaty, T. H., Fallin, M. D. & 4 others, Lee-Parritz, A., Zuckerman, B., Weeks, D. E. & Wang, X., Jun 9 2017, In : Nature communications. 8, 1 p.

Research output: Contribution to journalArticle

Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes

Vermillion, M. S., Lei, J., Shabi, Y., Baxter, V. K., Crilly, N. P., McLane, M., Griffin, D., Pekosz, A., Klein, S. L. & Burd, I., Feb 21 2017, In : Nature Communications. 8, 14575.

Research output: Contribution to journalArticle

In vivo assessment of the placental anatomy and perfusion in a mouse model of intrauterine inflammation

Wu, D., Lei, J., Jia, B., Xie, H., Zhu, Y., Xu, J., Mori, S., Zhang, J. & Burd, I., 2017, (Accepted/In press) In : Journal of Magnetic Resonance Imaging.

Research output: Contribution to journalArticle

Long-term impact of intrauterine neuroinflammation and treatment with magnesium sulphate and betamethasone: Sex-specific differences in a preterm labor murine model

Thagard, A. S., Slack, J. L., Estrada, S. M., Kazanjian, A. A., Chan, S., Burd, I., Napolitano, P. G. & Ieronimakis, N., Dec 1 2017, In : Scientific Reports. 7, 1, 17883.

Research output: Contribution to journalArticle

Maternal CD8+ T-cell depletion alleviates intrauterine inflammation-induced perinatal brain injury

Lei, J., Xie, L., Zhao, H., Gard, C., Clemens, J. L., Mclane, M. W., Feller, M. C., Ozen, M., Novak, C., Alshehri, W., Alhejaily, N., Shabi, Y., Rosenzweig, J. M., Facciabene, A. & Burd, I., Jan 1 2017, (Accepted/In press) In : American Journal of Reproductive Immunology.

Research output: Contribution to journalArticle

Maternal dendrimer-based therapy for inflammation-induced preterm birth and perinatal brain injury

Lei, J., Rosenzweig, J. M., Mishra, M. K., Alshehri, W., Brancusi, F., McLane, M., Almalki, A., Bahabry, R., Arif, H., Rozzah, R., Alyousif, G., Shabi, Y., Alhehaily, N., Zhong, W., Facciabene, A., Kannan, S., Rangaramanujam, K. & Burd, I., Dec 1 2017, In : Scientific Reports. 7, 1, 6106.

Research output: Contribution to journalArticle

Maternal vascular malperfusion of the placental bed associated with hypertensive disorders in the Boston Birth Cohort

Bustamante Helfrich, B., Chilukuri, N., He, H., Cerda, S. R., Hong, X., Wang, G., Pearson, C., Burd, I. & Wang, X., Apr 1 2017, In : Placenta. 52, p. 106-113 8 p.

Research output: Contribution to journalArticle

P2X7 receptor blockade prevents preterm birth and perinatal brain injury in a mouse model of intrauterine inflammation

Tsimis, M. E., Lei, J., Rosenzweig, J. M., Arif, H., Shabi, Y., Alshehri, W., Talbot, C. C., Baig-Ward, K. M., Segars, J., Graham, E. M. & Burd, I., Aug 1 2017, In : Biology of Reproduction. 97, 2, p. 230-239 10 p.

Research output: Contribution to journalArticle

Placental Characteristics of Fetuses with Congenital Heart Disease

Albalawi, A., Brancusi, F., Askin, F. B., Ehsanipoor, R., Wang, J., Burd, I. & Sekar, P., May 1 2017, In : Journal of Ultrasound in Medicine. 36, 5, p. 965-972 8 p.

Research output: Contribution to journalArticle

PlGF enhances TLR-dependent inflammatory responses in human mononuclear phagocytes

Newell, L. F., Holtan, S. G., Yates, J. E., Pereira, L., Tyner, J. W., Burd, I. & Bagby, G. C., 2017, (Accepted/In press) In : American Journal of Reproductive Immunology.

Research output: Contribution to journalArticle