Huijun Wei

Assistant Professor

20012019
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Fingerprint Dive into the research topics where Huijun Wei is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Arrestin Medicine & Life Sciences
Mitogen-Activated Protein Kinase 3 Medicine & Life Sciences
Mitogen-Activated Protein Kinase 1 Medicine & Life Sciences
Angiotensin Receptors Medicine & Life Sciences
GTP-Binding Proteins Medicine & Life Sciences
Protein Phosphatase 2 Medicine & Life Sciences
Angiotensin Type 1 Receptor Medicine & Life Sciences
Protein Isoforms Medicine & Life Sciences

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Research Output 2001 2019

Synthesis and characterization of novel isoform-selective IP6K1 inhibitors

Wormald, M. M., Ernst, G., Wei, H. & Barrow, J., Oct 1 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 19, 126628.

Research output: Contribution to journalArticle

Protein Isoforms
Solubility
Lead compounds
Phenotype
Physiology

Novel inhibitors of As(III) S-adenosylmethionine methyltransferase (AS3MT) identified by virtual screening

Bürli, R. W., Wei, H., Ernst, G., Mariga, A., Hardern, I. M., Herlihy, K., Cross, A. J., Wesolowski, S. S., Chen, H., McKay, R. D. G., Weinberger, D., Brandon, N. J. & Barrow, J., Oct 15 2018, In : Bioorganic and Medicinal Chemistry Letters. 28, 19, p. 3231-3235 5 p.

Research output: Contribution to journalArticle

S-Adenosylmethionine
Methyltransferases
Screening
Enzyme Assays
Scaffolds

Optimization of 8-Hydroxyquinolines as Inhibitors of Catechol O-Methyltransferase

Buchler, I., Akuma, D., Au, V., Carr, G., De León, P., Depasquale, M., Ernst, G., Huang, Y., Kimos, M., Kolobova, A., Poslusney, M., Wei, H., Swinnen, D., Montel, F., Moureau, F., Jigorel, E., Schulze, M. S. E. D., Wood, M. & Barrow, J., Nov 8 2018, In : Journal of Medicinal Chemistry. 61, 21, p. 9647-9665 19 p.

Research output: Contribution to journalArticle

Oxyquinoline
Dopamine
Catalytic Domain
Quinolines
Catechol O-Methyltransferase

Development of a homogenous high-throughput assay for inositol hexakisphosphate kinase 1 activity

Wormald, M., Liao, G., Kimos, M., Barrow, J. & Wei, H., Nov 1 2017, In : PLoS One. 12, 11, e0188852.

Research output: Contribution to journalArticle

Assays
phosphotransferases (kinases)
Throughput
Inositol
assays

A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophrenia-associated locus

Li, M., Jaffe, A., Straub, R. E., Tao, R., Shin, J. H., Wang, Y., Chen, Q., Li, C., Jia, Y., Ohi, K., Maher, B., Brandon, N. J., Cross, A., Chenoweth, J. G., Hoeppner, D. J., Wei, H., Hyde, T., McKay, R., Kleinman, J. & Weinberger, D., Jun 1 2016, In : Nature Medicine. 22, 6, p. 649-656 8 p.

Research output: Contribution to journalArticle

Schizophrenia
Protein Isoforms
Genes
Polymorphism
Minisatellite Repeats