Huijun Wei

Assistant Professor

20012019
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Fingerprint Dive into the research topics where Huijun Wei is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
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Research Output 2001 2019

Development of a PC12 Cell Based Assay for Screening Catechol- O-methyltransferase Inhibitors

Zhang, G., Buchler, I. P., Depasquale, M., Wormald, M., Liao, G., Wei, H., Barrow, J. & Carr, G., Oct 16 2019, In : ACS Chemical Neuroscience. 10, 10, p. 4221-4226 6 p.

Research output: Contribution to journalArticle

PC12 Cells
Catechol O-Methyltransferase
Assays
Screening
Metabolites

Synthesis and characterization of novel isoform-selective IP6K1 inhibitors

Wormald, M. M., Ernst, G., Wei, H. & Barrow, J., Oct 1 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 19, 126628.

Research output: Contribution to journalArticle

Protein Isoforms
Solubility
Lead compounds
Phenotype
Physiology

Synthesis and Evaluation of Bicyclic Hydroxypyridones as Inhibitors of Catechol O-Methyltransferase

Ernst, G., Akuma, D., Au, V., Buchler, I. P., Byers, S., Carr, G. V., Defays, S., De León, P., Demaude, T., Depasquale, M., Durieu, V., Huang, Y., Jigorel, E., Kimos, M., Kolobova, A., Montel, F., Moureau, F., Poslusney, M., Swinnen, D., Vandergeten, M. C. & 5 others, Van Houtvin, N., Wei, H., White, N., Wood, M. & Barrow, J. C., Jan 1 2019, (Accepted/In press) In : ACS Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

Rats
Pyridones
Catechol O-Methyltransferase
Pharmacokinetics
Biomarkers

Novel inhibitors of As(III) S-adenosylmethionine methyltransferase (AS3MT) identified by virtual screening

Bürli, R. W., Wei, H., Ernst, G., Mariga, A., Hardern, I. M., Herlihy, K., Cross, A. J., Wesolowski, S. S., Chen, H., McKay, R. D. G., Weinberger, D., Brandon, N. J. & Barrow, J., Oct 15 2018, In : Bioorganic and Medicinal Chemistry Letters. 28, 19, p. 3231-3235 5 p.

Research output: Contribution to journalArticle

S-Adenosylmethionine
Methyltransferases
Screening
Enzyme Assays
Scaffolds

Optimization of 8-Hydroxyquinolines as Inhibitors of Catechol O-Methyltransferase

Buchler, I., Akuma, D., Au, V., Carr, G., De León, P., Depasquale, M., Ernst, G., Huang, Y., Kimos, M., Kolobova, A., Poslusney, M., Wei, H., Swinnen, D., Montel, F., Moureau, F., Jigorel, E., Schulze, M. S. E. D., Wood, M. & Barrow, J., Nov 8 2018, In : Journal of Medicinal Chemistry. 61, 21, p. 9647-9665 19 p.

Research output: Contribution to journalArticle

Oxyquinoline
Dopamine
Catalytic Domain
Quinolines
Catechol O-Methyltransferase