Henry R Halperin

Professor

1982 …2019
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Research Output 1982 2019

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Article
2019

Ablation Lesion Characterization in Scarred Substrate Assessed Using Cardiac Magnetic Resonance

Tao, S., Guttman, M. A., Fink, S., Elahi, H., Patil, K. D., Ashikaga, H., Kolandaivelu, A., Berger, R. D., Halushka, M. K., Schmidt, E., Herzka, D. & Halperin, H. R., Jan 1 2019, In : JACC: Clinical Electrophysiology. 5, 1, p. 91-100 10 p.

Research output: Contribution to journalArticle

Catheter Ablation
Cicatrix
Magnetic Resonance Spectroscopy
Myocardium
Histology
Pulmonary Veins
Heart Atria
Radio
Swine
Pathology

Applications of a deep learning method for anti-aliasing and super-resolution in MRI

Zhao, C., Shao, M., Carass, A., Li, H., Dewey, B. E., Ellingsen, L. M., Woo, J., Guttman, M. A., Blitz, A. M., Stone, M., Calabresi, P. A., Halperin, H. & Prince, J. L., Jan 1 2019, In : Magnetic Resonance Imaging.

Research output: Contribution to journalArticle

Anti-aliasing
Magnetic resonance
Magnetic resonance imaging
Magnetic Resonance Spectroscopy
Learning

Effect of high flow transnasal dry air on core body temperature in intubated human subjects

Chava, R., Zviman, M., Assis, F. R., Raghavan, M. S., Halperin, H. R., Maqbool, F., Geocadin, R., Quinones-Hinojosa, A., Kolandaivelu, A., Rosen, B. A. & Tandri, H., Jan 1 2019, In : Resuscitation. 134, p. 49-54 6 p.

Research output: Contribution to journalArticle

Body Temperature
Hypothermia
Air
Temperature
Nasopharynx

Efficacy and Safety of Transnasal CoolStat Cooling Device to Induce and Maintain Hypothermia

Assis, F. R., Bigelow, M. E. G., Chava, R., Sidhu, S., Kolandaivelu, A., Halperin, H. R. & Tandri, H., Jun 1 2019, In : Therapeutic Hypothermia and Temperature Management. 9, 2, p. 108-117 10 p.

Research output: Contribution to journalArticle

Hypothermia
Safety
Equipment and Supplies
Temperature
Air

The Evolving Role of the Cardiac Catheterization Laboratory in the Management of Patients With Out-of-Hospital Cardiac Arrest: A Scientific Statement From the American Heart Association

American Heart Association Emergency Cardiovascular Care Committee, Mar 19 2019, In : Circulation. 139, 12, p. e530-e552

Research output: Contribution to journalArticle

Open Access
Out-of-Hospital Cardiac Arrest
Cardiac Catheterization
Ventricular Fibrillation
Ventricular Tachycardia
Coronary Artery Disease
2018

CPR Training in the United States: The Need for a New Gold Standard (and the Gold to Create It)

Brown, L. E. & Halperin, H. R., Sep 28 2018, In : Circulation Research. 123, 8, p. 950-952 3 p.

Research output: Contribution to journalArticle

Cardiopulmonary Resuscitation
Gold
Heart Arrest
Mortality

Personalized virtual-heart technology for guiding the ablation of infarct-related ventricular tachycardia

Prakosa, A., Arevalo, H. J., Deng, D., Boyle, P. M., Nikolov, P. P., Ashikaga, H., Blauer, J. J. E., Ghafoori, E., Park, C. J., Blake, R. C., Han, F. T., MacLeod, R. S., Halperin, H. R., Callans, D. J., Ranjan, R., Chrispin, J., Nazarian, S. & Trayanova, N. A., Jan 1 2018, (Accepted/In press) In : Nature Biomedical Engineering.

Research output: Contribution to journalArticle

Ventricular Tachycardia
Ablation
Technology
Prospective Studies
Sudden Cardiac Death

Precision of regional wall motion estimates from ultra-low-dose cardiac CT using SQUEEZ

Pourmorteza, A., Keller, N., Chen, R., Lardo, A., Halperin, H. R., Chen, M. Y. & McVeigh, E., Mar 13 2018, (Accepted/In press) In : International Journal of Cardiovascular Imaging. p. 1-10 10 p.

Research output: Contribution to journalArticle

Noise
Tomography
Myocardium
Diastole
Systole
Ventricular Tachycardia
Cicatrix
Swine
Tissue Distribution
Diffusion Magnetic Resonance Imaging
2017

A Novel, 5-Minute, Multisensory Training Session to Teach High-Quality Cardiopulmonary Resuscitation to the Public: Alive in Five

Brown, L. E., Bottinor, W., Tripathi, A., Carroll, T., DIllon, W. C., Lokits, C., Halperin, H. R. & Hirsch, G. A., Jun 1 2017, In : Circulation: Cardiovascular Quality and Outcomes. 10, 6

Research output: Contribution to journalArticle

Cardiopulmonary Resuscitation
Poverty
Heart Arrest
Education

CPR skill retention in 795 high school students following a 45-minute course with psychomotor practice

Brown, L. E., Carroll, T., Lynes, C., Tripathi, A., Halperin, H. R. & Dillon, W. C., 2017, (Accepted/In press) In : American Journal of Emergency Medicine.

Research output: Contribution to journalArticle

Out-of-Hospital Cardiac Arrest
Cardiopulmonary Resuscitation
Students

Imaging-Based Simulations for Predicting Sudden Death and Guiding Ventricular Tachycardia Ablation

Trayanova, N. A., Pashakhanloo, F., Wu, K. C-C. & Halperin, H. R., Jul 1 2017, In : Circulation: Arrhythmia and Electrophysiology. 10, 7, e004743.

Research output: Contribution to journalArticle

Implantable Defibrillators
Ventricular Tachycardia
Sudden Death
Cardiac Arrhythmias
Myocardial Infarction

MRI use for atrial tissue characterization in arrhythmias and for EP procedure guidance

Schmidt, E. & Halperin, H. R., Jun 7 2017, (Accepted/In press) In : International Journal of Cardiovascular Imaging. p. 1-15 15 p.

Research output: Contribution to journalArticle

Cardiac Arrhythmias
Utilization Review
Atrial Fibrillation
Magnetic Resonance Imaging
Therapeutics

Non-contrast-enhanced T1-weighted MRI of myocardial radiofrequency ablation lesions

Guttman, M. A., Tao, S., Fink, S., Kolandaivelu, A., Halperin, H. R. & Herzka, D., 2017, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Necrosis
Cicatrix
Histology
Myocardial Infarction
Pathology

Rapid Induction of Therapeutic Hypothermia Using Transnasal High Flow Dry Air

Chava, R., Zviman, M., Raghavan, M. S., Halperin, H. R., Maqbool, F., Geocadin, R., Quinones-Hinojosa, A., Kolandaivelu, A., Rosen, B. A. & Tandri, H., Mar 1 2017, In : Therapeutic hypothermia and temperature management. 7, 1, p. 50-56 7 p.

Research output: Contribution to journalArticle

Induced Hypothermia
Air
Temperature
Brain
Swine

Safety of magnetic resonance imaging in patients with cardiac devices

Nazarian, S., Hansford, R., Rahsepar, A. A., Weltin, V., McVeigh, D., Ipek, E. G., Kwan, A., Berger, R. D., Calkins, H., Lardo, A. C., Kraut, M. A., Kamel, I. R., Zimmerman, S. & Halperin, H. R., Dec 28 2017, In : New England Journal of Medicine. 377, 26, p. 2555-2564 10 p.

Research output: Contribution to journalArticle

Magnetic Resonance Imaging
Safety
Equipment and Supplies
Implantable Defibrillators
Defibrillators

Submillimeter diffusion tensor imaging and late gadolinium enhancement cardiovascular magnetic resonance of chronic myocardial infarction

Pashakhanloo, F., Herzka, D., Mori, S., Zviman, M., Halperin, H. R., Gai, N., Bluemke, D. A., Trayanova, N. A. & McVeigh, E. R., Jan 11 2017, In : Journal of Cardiovascular Magnetic Resonance. 19, 1, 9.

Research output: Contribution to journalArticle

Diffusion Tensor Imaging
Gadolinium
Magnetic Resonance Spectroscopy
Myocardial Infarction
Cicatrix
2016

Feasibility of using patient-specific models and the "minimum cut" algorithm to predict optimal ablation targets for left atrial flutter

Zahid, S., Whyte, K. N., Schwarz, E. L., Blake, R. C., Boyle, P. M., Chrispin, J., Prakosa, A., Ipek, E. G., Pashakhanloo, F., Halperin, H. R., Calkins, H., Berger, R. D., Nazarian, S. & Trayanova, N. A., 2016, (Accepted/In press) In : Heart Rhythm.

Research output: Contribution to journalArticle

Atrial Flutter
Catheter Ablation
Computer Simulation
Gadolinium
Atrial Fibrillation
Cardiac Resynchronization Therapy
Canidae
Electrocardiography
Heart Failure
Tomography

Non-invasive electromechanical activation imaging as a tool to study left ventricular dyssynchronous patients: Implication for CRT therapy

Dawoud, F., Spragg, D. D., Berger, R. D., Cheng, A., Horáček, B. M., Halperin, H. R. & Lardo, A. C., 2016, (Accepted/In press) In : Journal of Electrocardiology.

Research output: Contribution to journalArticle

Cardiac Resynchronization Therapy
Therapeutics
Direction compound

Real-time free-breathing cardiac imaging with self-calibrated through-time radial GRAPPA

Sayin, O., Saybasili, H., Zviman, M. M., Griswold, M., Halperin, H. R., Seiberlich, N. & Herzka, D., 2016, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Respiration
Calibration
Swine
Gold
Implantable Defibrillators
Shock
Pain
Skeletal Muscle
Aptitude
2015

Accuracy of prediction of infarct-related arrhythmic circuits from image-based models reconstructed from low and high resolution MRI

Deng, D., Arevalo, H., Pashakhanloo, F., Prakosa, A., Ashikaga, H., McVeigh, E., Halperin, H. R. & Trayanova, N., 2015, In : Frontiers in Physiology. 6, OCT, 282.

Research output: Contribution to journalArticle

Ventricular Tachycardia
Swine
Computer Simulation
Epicardial Mapping
Gadolinium

Cardiac Arrest: the Changing Incidence of Ventricular Fibrillation

Keller, S. P. & Halperin, H. R., Jul 22 2015, In : Current Treatment Options in Cardiovascular Medicine. 17, 7, 1.

Research output: Contribution to journalArticle

Ventricular Fibrillation
Heart Arrest
Out-of-Hospital Cardiac Arrest
Incidence
Implantable Defibrillators

Cardiac Arrest: Resuscitation and Reperfusion

Patil, K. D., Halperin, H. R. & Becker, L. B., Jun 5 2015, In : Circulation Research. 116, 12, p. 2041-2049 9 p.

Research output: Contribution to journalArticle

Heart Arrest
Resuscitation
Reperfusion
Defibrillators
Cardiopulmonary Resuscitation

High-resolution whole-heart 3D T2 mapping can assess tissue heterogeneity of chronic MI in swine

Ding, H., Schuleri, K. H., Schär, M., Halperin, H. R., Beinart, R., Zviman, M. M. & Herzka, D. A., Feb 3 2015, (Accepted/In press) In : Journal of Cardiovascular Magnetic Resonance. p. 1-3 3 p.

Research output: Contribution to journalArticle

Swine

MRI Evaluation of Radiofrequency, Cryothermal, and Laser Left Atrial Lesion Formation in Patients with Atrial Fibrillation

Khurram, I. M., Catanzaro, J. N., Zimmerman, S., Zipunnikov, V., Berger, R. D., Cheng, A., Sinha, S., Dewire, J., Marine, J., Spragg, D. D., Ashikaga, H., Halperin, H. R., Calkins, H. & Nazarian, S., Nov 1 2015, In : PACE - Pacing and Clinical Electrophysiology. 38, 11, p. 1317-1324 8 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Cicatrix
Lasers
Pulmonary Veins
Gadolinium

Non-contrast T1 and T2 relaxometry characterizes reperfusion injury of acute MI in swine

Ding, H., Schär, M., Schuleri, K. H., Halperin, H. R., Zviman, M. M., Beinart, R. & Herzka, D. A., Feb 3 2015, (Accepted/In press) In : Journal of Cardiovascular Magnetic Resonance. p. 1-2 2 p.

Research output: Contribution to journalArticle

Reperfusion Injury
Swine

Part 7: Adult advanced cardiovascular life support: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care

Link, M. S., Berkow, L. C., Kudenchuk, P. J., Halperin, H. R., Hess, E. P., Moitra, V. K., Neumar, R. W., O'Neil, B. J., Paxton, J. H., Silvers, S. M., White, R. D., Yannopoulos, D. & Donnino, M. W., Oct 20 2015, In : Circulation. 132, 18, p. S444-S464

Research output: Contribution to journalArticle

Oxygen Inhalation Therapy
Out-of-Hospital Cardiac Arrest
Electric Countershock
Extracorporeal Membrane Oxygenation
Airway Management

Quality of CPR: An important effect modifier in cardiac arrest clinical outcomes and intervention effectiveness trials

Yannopoulos, D., Aufderheide, T. P., Abella, B. S., Duval, S., Frascone, R. J., Goodloe, J. M., Mahoney, B. D., Nadkarni, V. M., Halperin, H. R., O'Connor, R., Idris, A. H., Becker, L. B. & Pepe, P. E., Sep 1 2015, In : Resuscitation. 94, p. 106-113 8 p.

Research output: Contribution to journalArticle

Cardiopulmonary Resuscitation
Heart Arrest
North America
Databases
Survival

Three-dimensional whole-heart T2 mapping at 3T

Ding, H., Fernandez-De-Manuel, L., Schar, M., Schuleri, K. H., Halperin, H. R., He, L., Zviman, M. M., Beinart, R. & Herzka, D., Sep 1 2015, In : Magnetic Resonance in Medicine. 74, 3, p. 803-816 14 p.

Research output: Contribution to journalArticle

Respiration
Swine
Myocardium
Heart Rate
Myocardial Infarction
2014

Facilitation of transvenous lead extraction using site-specific delivery of electrosurgical energy

Catanzaro, J. N., Zviman, M., Kolandaivelu, A., Nazarian, S., Halperin, H. R., Berger, R. D., Brinker, J. A. & Cheng, A., 2014, In : IJC Heart and Vessels. 3, p. 75-77 3 p.

Research output: Contribution to journalArticle

Defibrillators
Excimer Lasers
Traction
Transducers
Blood Vessels

Magnetic resonance image intensity ratio, a normalized measure to enable interpatient comparability of left atrial fibrosis

Khurram, I. M., Beinart, R., Zipunnikov, V., Dewire, J., Yarmohammadi, H., Sasaki, T., Spragg, D. D., Marine, J., Berger, R. D., Halperin, H. R., Calkins, H., Zimmerman, S. & Nazarian, S., Jan 2014, In : Heart Rhythm. 11, 1, p. 85-92 8 p.

Research output: Contribution to journalArticle

Gadolinium
Cicatrix
Fibrosis
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging

Methodology for image-based reconstruction of ventricular geometry for patient-specific modeling of cardiac electrophysiology

Prakosa, A., Malamas, P., Zhang, S., Pashakhanloo, F., Arevalo, H., Herzka, D., Lardo, A., Halperin, H. R., McVeigh, E., Trayanova, N. & Vadakkumpadan, F., Aug 1 2014, In : Progress in Biophysics and Molecular Biology. 115, 2-3, p. 226-234 9 p.

Research output: Contribution to journalArticle

Cardiac Electrophysiology
Computer-Assisted Image Processing
Magnetic Resonance Spectroscopy
Electrophysiology
Electrocardiography
Image resolution
Optical resolving power
Cicatrix
Gadolinium
Imaging techniques
2013

Cardiac magnetic resonance T1 mapping of left atrial myocardium

Beinart, R., Khurram, I. M., Liu, S., Yarmohammadi, H., Halperin, H. R., Bluemke, D. A., Gai, N., Van Der Geest, R. J., Lima, J., Calkins, H., Zimmerman, S. & Nazarian, S., Sep 2013, In : Heart Rhythm. 10, 9, p. 1325-1331 7 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Cardiac Electrophysiologic Techniques
Myocardium
Healthy Volunteers
Magnetic Resonance Spectroscopy

Feasibility of image-based simulation to estimate ablation target in human ventricular arrhythmia

Ashikaga, H., Arevalo, H., Vadakkumpadan, F., Blake, R. C., Bayer, J. D., Nazarian, S., Muz Zviman, M., Tandri, H., Berger, R. D., Calkins, H., Herzka, D., Trayanova, N. A. & Halperin, H. R., Aug 2013, In : Heart Rhythm. 10, 8, p. 1109-1116 8 p.

Research output: Contribution to journalArticle

Ventricular Tachycardia
Cardiac Arrhythmias
Cicatrix
Gadolinium
Magnetic Resonance Imaging

Impact of nonischemic scar features on local ventricular electrograms and scar-related ventricular tachycardia circuits in patients with nonischemic cardiomyopathy

Sasaki, T., Miller, C., Hansford, R., Zipunnikov, V., Zviman, M. M., Marine, J., Spragg, D. D., Cheng, A., Tandri, H., Sinha, S., Kolandaivelu, A., Zimmerman, S., Bluemke, D. A., Tomaselli, G. F., Berger, R. D., Halperin, H. R., Calkins, H. & Nazarian, S., Dec 2013, In : Circulation: Arrhythmia and Electrophysiology. 6, 6, p. 1139-1147 9 p.

Research output: Contribution to journalArticle

Ventricular Tachycardia
Cardiomyopathies
Cicatrix
Gadolinium
Magnetic Resonance Spectroscopy
Conducted Energy Weapon Injuries
Sudden Cardiac Death
Ventricular Fibrillation
Heart Arrest
Shock

Magnetic resonance imaging and implantable devices

Nazarian, S., Beinart, R. & Halperin, H. R., Apr 2013, In : Circulation: Arrhythmia and Electrophysiology. 6, 2, p. 419-428 10 p.

Research output: Contribution to journalArticle

Artificial Pacemaker
Cine Magnetic Resonance Imaging
Implantable Defibrillators
Reproducibility of Results
Cardiac Arrhythmias

Predictors of high defibrillation threshold in the modern era

Lin, E. F., Dalal, D., Cheng, A., Marine, J., Nazarian, S., Sinha, S., Spragg, D. D., Tandri, H., Halperin, H. R., Calkins, H., Berger, R. D., Tomaselli, G. F. & Henrikson, C. A., Feb 2013, In : PACE - Pacing and Clinical Electrophysiology. 36, 2, p. 231-237 7 p.

Research output: Contribution to journalArticle

Stroke Volume
Implantable Defibrillators
Cardiomyopathies
Multivariate Analysis
Retrospective Studies

Pulseless electric activity: Definition, causes, mechanisms, management, and research priorities for the next decade: Report from a national heart, lung, and blood institute workshop

Myerburg, R. J., Halperin, H. R., Egan, D. A., Boineau, R., Chugh, S. S., Gillis, A. M., Goldhaber, J. I., Lathrop, D. A., Liu, P., Niemann, J. T., Ornato, J. P., Sopko, G., Van Eyk, J. E., Walcott, G. P., Weisfeldt, M., Wright, J. D. & Zipes, D. P., Dec 3 2013, In : Circulation. 128, 23, p. 2532-2541 10 p.

Research output: Contribution to journalArticle

National Heart, Lung, and Blood Institute (U.S.)
Sudden Cardiac Death
Disease Management
Heart Arrest
Cardiac Arrhythmias

Significance of leukocytosis after cardiac device implantation

Tompkins, C., Cheng, A., Brinker, J. A., Marine, J., Nazarian, S., Spragg, D. D., Sinha, S., Halperin, H. R., Tomaselli, G. F., Berger, R. D., Calkins, H. & Henrikson, C. A., Jun 1 2013, In : The American Journal of Cardiology. 111, 11, p. 1608-1612 5 p.

Research output: Contribution to journalArticle

Leukocytosis
Equipment and Supplies
Infection
Implantable Defibrillators
Bacteremia

Tachycardia in Post-Infarction Hearts: Insights from 3D Image-Based Ventricular Models

Arevalo, H., Plank, G., Helm, P., Halperin, H. R. & Trayanova, N., Jul 2 2013, In : PLoS One. 8, 7, e68872.

Research output: Contribution to journalArticle

infarction
Tachycardia
Infarction
heart
Cicatrix
2012

Atrial fibrillation and diffuse left ventricular fibrosis, a causal association?

Halperin, H. R. & Nazarian, S., Dec 11 2012, In : Journal of the American College of Cardiology. 60, 23, p. 2409-2410 2 p.

Research output: Contribution to journalArticle

Cine Magnetic Resonance Imaging
Left Ventricular Dysfunction
Cardiomyopathies
Atrial Fibrillation
Myocardium

Coronary perfusion pressure during external chest compression in pseudo-EMD, comparison of systolic versus diastolic synchronization

Paradis, N. A., Halperin, H. R., Zviman, M., Barash, D., Quan, W. & Freeman, G., Oct 2012, In : Resuscitation. 83, 10, p. 1287-1291 5 p.

Research output: Contribution to journalArticle

Thorax
Perfusion
Pressure
Diastole
Systole

Ischemic postconditioning at the initiation of cardiopulmonary resuscitation facilitates functional cardiac and cerebral recovery after prolonged untreated ventricular fibrillation

Segal, N., Matsuura, T., Caldwell, E., Sarraf, M., McKnite, S., Zviman, M., Aufderheide, T. P., Halperin, H. R., Lurie, K. G. & Yannopoulos, D., Nov 2012, In : Resuscitation. 83, 11, p. 1397-1403 7 p.

Research output: Contribution to journalArticle

Ischemic Postconditioning
Cardiopulmonary Resuscitation
Ventricular Fibrillation
Resuscitation
Swine

Mechanical devices for cardiopulmonary resuscitation

Halperin, H. R., Apr 2012, In : Critical Care Clinics. 28, 2, p. 167-187 21 p.

Research output: Contribution to journalArticle

Medical Illustration
Equipment Design
Cardiopulmonary Resuscitation
Critical Care
Heart Arrest

Myocardial structural associations with local electrograms: A study of postinfarct ventricular tachycardia pathophysiology and magnetic resonance-based noninvasive mapping

Sasaki, T., Miller, C., Hansford, R., Yang, J., Caffo, B. S., Zviman, M. M., Henrikson, C. A., Marine, J., Spragg, D. D., Cheng, A., Tandri, H., Sinha, S., Kolandaivelu, A., Zimmerman, S., Bluemke, D. A., Tomaselli, G. F., Berger, R. D., Calkins, H., Halperin, H. R. & Nazarian, S., Dec 2012, In : Circulation: Arrhythmia and Electrophysiology. 5, 6, p. 1081-1090 10 p.

Research output: Contribution to journalArticle

Ventricular Tachycardia
Cicatrix
Gadolinium
Magnetic Resonance Spectroscopy
Anti-Arrhythmia Agents