1974 …2020
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Research Output 1974 2020

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2020

Nonviral polymeric nanoparticles for gene therapy in pediatric CNS malignancies

Choi, J., Rui, Y., Kim, J., Gorelick, N., Wilson, D. R., Kozielski, K., Mangraviti, A., Sankey, E., Brem, H., Tyler, B., Green, J. J. & Jackson, E. M., Jan 2020, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 23, 102115.

Research output: Contribution to journalArticle

Gene therapy
Pediatrics
Genetic Therapy
Nanoparticles
Viruses
2019

Biodegradable wafers releasing Temozolomide and Carmustine for the treatment of brain cancer

Shapira-Furman, T., Serra, R., Gorelick, N., Doglioli, M., Tagliaferri, V., Cecia, A., Peters, M., Kumar, A., Rottenberg, Y., Langer, R., Brem, H., Tyler, B. M. & Domb, A. J., Feb 10 2019, In : Journal of Controlled Release. 295, p. 93-101 9 p.

Research output: Contribution to journalArticle

temozolomide
Carmustine
Brain Neoplasms
Polymers
Glioblastoma

Combination anti-CXCR4 and anti-PD-1 immunotherapy provides survival benefit in glioblastoma through immune cell modulation of tumor microenvironment

Wu, A., Maxwell, R., Xia, Y., Cardarelli, P., Oyasu, M., Belcaid, Z., Kim, E., Hung, A., Luksik, A. S., Garzon-Muvdi, T., Jackson, C. M., Mathios, D., Theodros, D., Cogswell, J., Brem, H., Pardoll, A. M. & Lim, M., Jan 1 2019, In : Journal of neuro-oncology.

Research output: Contribution to journalArticle

Tumor Microenvironment
Glioblastoma
Immunotherapy
Glioma
Myeloid Cells

Deferred radiotherapy after debulking of non-functioning pituitary macroadenomas: Clinical outcomes

Nicholas, S. E., Salvatori, R., Quinones-Hinojosa, A., Redmond, K. A., Gallia, G. L., Lim, M., Rigamonti, D., Brem, H. & Kleinberg, L. R., Jan 1 2019, In : Frontiers in Oncology. 9, JAN, 660.

Research output: Contribution to journalArticle

Open Access
Radiotherapy
Adenoma
Optic Chiasm
Pituitary Neoplasms
Headache
Fascia
Transplants
Neurosurgical Procedures
Craniotomy
Research Ethics Committees

First-in-Human Experience With Integration of a Hydrocephalus Shunt Device Within a Customized Cranial Implant

Gordon, C. R., Wolff, A., Santiago, G. F., Liebman, K., Veznedaroglu, E., Vrionis, F. D., Huang, J., Brem, H. & Luciano, M., Dec 1 2019, In : Operative neurosurgery (Hagerstown, Md.). 17, 6, p. 608-615 8 p.

Research output: Contribution to journalArticle

Open Access
Hydrocephalus
Scalp
Equipment and Supplies
Patient Satisfaction
Anti-Bacterial Agents

Full-Thickness Skin Grafting for Local Defect Coverage Following Scalp Adjacent Tissue Transfer in the Setting of Cranioplasty

Wolff, A. Y., Santiago, G. F., Belzberg, M., Manson, P., Huang, J., Brem, H. & Gordon, C. R., Jan 1 2019, In : The Journal of craniofacial surgery. 30, 1, p. 115-119 5 p.

Research output: Contribution to journalArticle

Skin Transplantation
Scalp
Transplants
Skin
Bone and Bones

Genome-wide investigation of intragenic DNA methylation identifies ZMIZ1 gene as a prognostic marker in glioblastoma and multiple cancer types

Mathios, D., Hwang, T., Xia, Y., Phallen, J., Rui, Y., See, A. P., Maxwell, R., Belcaid, Z., Casaos, J., Burger, P. C., McDonald, K. L., Gallia, G. L., Cope, L., Kai, M., Brem, H., Pardoll, A. M., Ha, P., Green, J., Velculescu, V. E., Bettegowda, C. & 2 others, Park, C. K. & Lim, M., Jan 1 2019, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

DNA Methylation
Glioblastoma
Genome
Genes
Neoplasms

Overall survival in malignant glioma is significantly prolonged by neurosurgical delivery of etoposide and temozolomide from a thermo-responsive biodegradable paste

Smith, S. J., Tyler, B. M., Gould, T., Veal, G. J., Gorelick, N., Rowlinson, J., Serra, R., Ritchie, A., Berry, P., Otto, A., Choi, J., Skuli, N., Estevez-Cebrero, M., Shakesheff, K. M., Brem, H., Grundy, R. G. & Rahman, R., Aug 15 2019, In : Clinical Cancer Research. 25, 16, p. 5094-5106 13 p.

Research output: Contribution to journalArticle

Open Access
temozolomide
Etoposide
Ointments
Glioma
Survival

Sonolucent cranial implants: Cadaveric study and clinical findings supporting diagnostic and therapeutic transcranioplasty ultrasound

Belzberg, M., Shalom, N. B., Yuhanna, E., Manbachi, A., Tekes, A., Huang, J., Brem, H. & Gordon, C. R., Jan 1 2019, In : Journal of Craniofacial Surgery. 30, 5, p. 1456-1461 6 p.

Research output: Contribution to journalArticle

Polymethyl Methacrylate
Bone and Bones
Anatomy
Therapeutics
Polyethylene
Polymethyl Methacrylate
Tomography
Magnetic Resonance Imaging
Diagnostic Imaging
Ultrasonography
2018

Adult cranioplasty reconstruction with customized cranial implants: Preferred technique, timing, and biomaterials

Wolff, A., Santiago, G. F., Belzberg, M., Huggins, C., Lim, M., Weingart, J. D., Anderson, W. S., Coon, A., Huang, J., Brem, H. & Gordon, C. R., Jun 1 2018, In : Journal of Craniofacial Surgery. 29, 4, p. 887-894 8 p.

Research output: Contribution to journalArticle

Biocompatible Materials
Methylmethacrylate
Inlays
Neurosurgery
Polyethylene

Contrasting impact of corticosteroids on anti-PD-1 immunotherapy efficacy for tumor histologies located within or outside the central nervous system

Maxwell, R., Luksik, A. S., Garzon-Muvdi, T., Hung, A. L., Kim, E. S., Wu, A., Xia, Y., Belcaid, Z., Gorelick, N., Choi, J., Theodros, D., Jackson, C. M., Mathios, D., Ye, X., Tran, P. T., Redmond, K. A., Brem, H., Pardoll, A. M., Kleinberg, L. R. & Lim, M., Jan 1 2018, (Accepted/In press) In : OncoImmunology.

Research output: Contribution to journalArticle

Immunotherapy
Histology
Adrenal Cortex Hormones
Central Nervous System
Neoplasms

Dendritic cell activation enhances anti-PD-1 mediated immunotherapy against glioblastoma

Garzon-Muvdi, T., Theodros, D., Luksik, A. S., Maxwell, R., Kim, E., Jackson, C. M., Belcaid, Z., Ganguly, S., Tyler, B. M., Brem, H., Pardoll, A. M. & Lim, M., Apr 17 2018, In : Oncotarget. 9, 29, p. 20681-20697 17 p.

Research output: Contribution to journalArticle

Glioblastoma
Immunotherapy
Dendritic Cells
Antigen Presentation
Neoplasms

Ethical Issues and Recommendations in Grateful Patient Fundraising and Philanthropy

Participants in the Summit on the Ethics of Grateful Patient Fundraising, Nov 1 2018, In : Academic medicine : journal of the Association of American Medical Colleges. 93, 11, p. 1631-1637 7 p.

Research output: Contribution to journalArticle

fundraising
philanthropy
physician
transparency
conflict of interest

Expression of LAG-3 and efficacy of combination treatment with anti-LAG-3 and anti-PD-1 monoclonal antibodies in glioblastoma

Harris-Bookman, S., Mathios, D., Martin, A., Xia, Y., Kim, E., Xu, H., Belcaid, Z., Polanczyk, M., Barberi, T., Theodros, D., Kim, J., Taube, J. M., Burger, P. C., Selby, M., Taitt, C., Korman, A., Ye, X., Drake, C. G., Brem, H., Pardoll, A. M. & 1 others, Lim, M., Jan 1 2018, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

Glioblastoma
Monoclonal Antibodies
Blocking Antibodies
Immunotherapy
Neoplasms
Equipment and Supplies
Partial Epilepsy
Bone Resorption
Osteomyelitis
United States Food and Drug Administration

Post-Neurosurgical Temporal Deformities: Various Techniques for Correction and Associated Complications

Santiago, G. F., Terner, J., Wolff, A., Teixeira, J., Brem, H., Huang, J. & Gordon, C. R., Oct 1 2018, In : The Journal of craniofacial surgery. 29, 7, p. 1723-1729 7 p.

Research output: Contribution to journalArticle

Fats
Temporal Lobe
Pulmonary Embolism
Reoperation
Dissection

Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors

Casaos, J., Huq, S., Lott, T., Felder, R., Choi, J., Gorelick, N., Peters, M., Xia, Y., Maxwell, R., Zhao, T., Ji, C., Simon, T., Sesen, J., Scotland, S. J., Kast, R. E., Rubens, J., Raabe, E., Eberhart, C. G., Jackson, E., Brem, H. & 2 others, Tyler, B. M. & Skuli, N., Jan 1 2018, In : Oncotarget. 9, 8, p. 8054-8067 14 p.

Research output: Contribution to journalArticle

Ribavirin
Therapeutics
Growth
Typical Teratoid Rhabdoid Tumor
Atypical Teratoid Tumor

Risk of Developing Postoperative Deficits Based on Tumor Location after Surgical Resection of an Intracranial Meningioma

Ehresman, J. S., Garzon-Muvdi, T., Rogers, D., Lim, M., Gallia, G. L., Weingart, J. D., Brem, H., Bettegowda, C. & Chaichana, K. L., Jul 17 2018, (Accepted/In press) In : Journal of Neurological Surgery, Part B: Skull Base.

Research output: Contribution to journalArticle

Meningioma
Confidence Intervals
Neoplasms
Acoustic Neuroma
Tertiary Healthcare

Targeted Local Therapy for Management of Intracranial High-Grade Gliomas

Paldor, I., Chaichana, K. L., Brem, H. & Tyler, B. M., Jan 1 2018, In : Progress in neurological surgery. 32, p. 159-171 13 p.

Research output: Contribution to journalArticle

Glioma
Neoplasms by Site
Oncolytic Viruses
Convection
Angiogenesis Inhibitors

The Relevance of Simpson Grade Resections in Modern Neurosurgical Treatment of World Health Organization Grade I, II, and III Meningiomas

Ehresman, J. S., Garzon-Muvdi, T., Rogers, D., Lim, M., Gallia, G. L., Weingart, J. D., Brem, H., Bettegowda, C. & Chaichana, K. L., Jan 1 2018, In : World Neurosurgery. 109, p. e588-e593

Research output: Contribution to journalArticle

Meningioma
Recurrence
Confidence Intervals
Therapeutics
Tertiary Healthcare

TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM

Hung, A. L., Maxwell, R., Theodros, D., Belcaid, Z., Mathios, D., Luksik, A. S., Kim, E., Wu, A., Xia, Y., Garzon-Muvdi, T., Jackson, C., Ye, X., Tyler, B. M., Selby, M., Korman, A., Barnhart, B., Park, S. M., Youn, J. I., Chowdhury, T., Park, C. K. & 3 others, Brem, H., Pardoll, A. M. & Lim, M., May 23 2018, (Accepted/In press) In : OncoImmunology.

Research output: Contribution to journalArticle

Glioblastoma
Immunity
Survival
Therapeutics
T-Lymphocytes
2017

Atypical and anaplastic meningioma: outcomes in a population based study

Garzon-Muvdi, T., Yang, W., Lim, M., Brem, H. & Huang, J., Apr 20 2017, (Accepted/In press) In : Journal of Neuro-Oncology. p. 1-10 10 p.

Research output: Contribution to journalArticle

Meningioma
Population
Neoplasms
Epidemiology
Radiotherapy

Central nervous system cancers, version 1.2017 featured updates to the NCCN guidelines

Nabors, L. B., Portnow, J., Ammirati, M., Baehring, J., Brem, H., Butowski, N., Fenstermaker, R. A., Forsyth, P., Hattangadi-Gluth, J., Holdhoff, M., Howard, S., Junck, L., Kaley, T., Kumthekar, P., Loeffler, J. S., Moots, P. L., Mrugala, M. M., Nagpal, S., Pandey, M., Parney, I. & 16 others, Peters, K., Puduvalli, V. K., Ragsdale, J., Rockhill, J., Rogers, L., Rusthoven, C., Shonka, N., Shrieve, D. C., Sills, A. K., Swinnen, L., Tsien, C., Weiss, S., Wen, P. Y., Willmarth, N., Bergman, M. A. & Engh, A., Nov 1 2017, In : JNCCN Journal of the National Comprehensive Cancer Network. 15, 11, p. 1331-1345 15 p.

Research output: Contribution to journalArticle

Glioma
Histology
Central Nervous System
Guidelines
Neoplasms

Combination therapy with anti-PD-1, anti-TIM-3, and focal radiation results in regression of murine gliomas

Kim, J. E., Patel, M. A., Mangraviti, A., Kim, E. S., Theodros, D., Velarde, E., Liu, A., Sankey, E. W., Tam, A., Xu, H., Mathios, D., Jackson, C. M., Harris-Bookman, S., Garzon-Muvdi, T., Sheu, M., Martin, A., Tyler, B. M., Tran, P. T., Ye, X., Olivi, A. & 6 others, Taube, J. M., Burger, P. C., Drake, C. G., Brem, H., Pardoll, A. M. & Lim, M., Jan 1 2017, In : Clinical Cancer Research. 23, 1, p. 124-136 13 p.

Research output: Contribution to journalArticle

Mucin-3
Glioma
Immunoglobulins
Radiation
T-Lymphocytes
Odds Ratio
Databases
Confidence Intervals
Costs and Cost Analysis
Health

Defining glioblastoma resectability through the wisdom of the crowd: A proof-of-principle study

Sonabend, A. M., Zacharia, B. E., Cloney, M. B., Sonabend, A., Showers, C., Ebiana, V., Nazarian, M., Swanson, K. R., Baldock, A., Brem, H., Bruce, J. N., Butler, W., Cahill, D. P., Carter, B., Orringer, D. A., Roberts, D. W., Sagher, O., Sanai, N., Schwartz, T. H., Silbergeld, D. L. & 4 others, Sisti, M. B., Thompson, R. C., Waziri, A. E. & McKhann, G., Apr 1 2017, In : Clinical Neurosurgery. 80, 4, p. 590-601 12 p.

Research output: Contribution to journalArticle

Glioblastoma
Crowdsourcing
Clinical Trials
Residual Neoplasm
Brain Neoplasms
Brain Neoplasms
Research
Carmustine
temozolomide
Therapeutics

HIF-1α- Targeting Acriflavine Provides Long Term Survival and Radiological Tumor Response in Brain Cancer Therapy

Mangraviti, A., Raghavan, T., Volpin, F., Skuli, N., Gullotti, D., Zhou, J., Asnaghi, L., Sankey, E., Liu, A., Wang, Y., Lee, D. H., Gorelick, N., Serra, R., Peters, M., Schriefer, D., Delaspre, F., Rodriguez, F. J., Eberhart, C. G., Brem, H., Olivi, A. & 1 others, Tyler, B. M., Dec 1 2017, In : Scientific Reports. 7, 1, 14978.

Research output: Contribution to journalArticle

Acriflavine
Brain Neoplasms
Survival
Neoplasms
Glioma

Metastatic Atypical and Anaplastic Meningioma: A Case Series and Review of the Literature

Kessler, R. A., Garzon-Muvdi, T., Yang, W., Weingart, J. D., Olivi, A., Huang, J., Brem, H. & Lim, M., May 1 2017, In : World Neurosurgery. 101, p. 47-56 10 p.

Research output: Contribution to journalArticle

Meningioma
Neoplasm Metastasis
Proxy
Spine
Radiation
Brain Neoplasms
Seizures
Temporal Lobe
Neoplasm Metastasis
Neoplasms

Starting a Medical Technology Venture as a Young Academic Innovator or Student Entrepreneur

Manbachi, A., Kreamer-Tonin, K., Walch, P., Gamo, N., Khoshakhlagh, P., Zhang, Y. S., Montague, C., Acharya, S., Logsdon, E. A., Allen, R. H., Durr, N. J., Luciano, M. G., Theodore, N., Brem, H. & Yazdi, Y., Oct 10 2017, (Accepted/In press) In : Annals of Biomedical Engineering. p. 1-13 13 p.

Research output: Contribution to journalArticle

Students
Patents and inventions
Ecosystems
Industry

The efficacy of lapatinib and nilotinib in combination with radiation therapy in a model of NF2 associated peripheral schwannoma

Paldor, I., Abbadi, S., Bonne, N., Ye, X., Rodriguez, F. J., Rowshanshad, D., Itzoe, M. L., Vigilar, V., Giovannini, M., Brem, H., Blakeley, J. & Tyler, B. M., Jul 22 2017, (Accepted/In press) In : Journal of Neuro-Oncology. p. 1-10 10 p.

Research output: Contribution to journalArticle

Neurofibromatosis 2
Neurilemmoma
Nerve Sheath Neoplasms
Radiotherapy
Radiation
2016

Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma

Patel, M. A., Kim, J. E., Theodros, D., Tam, A., Velarde, E., Kochel, C. M., Francica, B., Nirschl, T. R., Ghasemzadeh, A., Mathios, D., Harris-Bookman, S., Jackson, C. C., Jackson, C., Ye, X., Tran, P. T., Tyler, B. M., Coric, V., Selby, M., Brem, H., Drake, C. G. & 2 others, Pardoll, A. M. & Lim, M., May 17 2016, In : Journal for ImmunoTherapy of Cancer. 4, 1, 28.

Research output: Contribution to journalArticle

Radiosurgery
Glioma
Monoclonal Antibodies
Radiation
Glioblastoma

Anticoagulation for Hypercoagulable Patients Associated with Complications after Large Cranioplasty Reconstruction

Sankey, E. W., Lopez, J., Zhong, S. S., Susarla, H., Jusué-Torres, I., Liauw, J., Huang, J., Streiff, M. B., Brem, H. & Gordon, C. R., Feb 1 2016, In : Plastic and Reconstructive Surgery. 137, 2, p. 595-607 13 p.

Research output: Contribution to journalArticle

Logistic Models
Regression Analysis
Skull
Anticoagulants
Therapeutics

Anti-PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM

Mathios, D., Kim, J. E., Mangraviti, A., Phallen, J., Park, C. K., Jackson, C. M., Garzon-Muvdi, T., Kim, E., Theodros, D., Polanczyk, M., Martin, A., Suk, I., Ye, X., Tyler, B. M., Bettegowda, C., Brem, H., Pardoll, A. M. & Lim, M., Dec 21 2016, In : Science Translational Medicine. 8, 370, 370ra180.

Research output: Contribution to journalArticle

Immunity
Drug Therapy
Glioblastoma
Immunotherapy
Programmed Cell Death 1 Receptor

Convection enhanced delivery of cisplatin-loaded brain penetrating nanoparticles cures malignant glioma in rats

Zhang, C., Nance, E. A., Mastorakos, P., Chisholm, J., Berry, S., Eberhart, C. G., Tyler, B. M., Brem, H., Suk, J. S. & Hanes, J. S., Dec 5 2016, (Accepted/In press) In : Journal of Controlled Release.

Research output: Contribution to journalArticle

Convection
Glioma
Nanoparticles
Cisplatin
Brain

Defining Glioblastoma Resectability Through the Wisdom of the Crowd: A Proof-of-Principle Study

Sonabend, A. M., Zacharia, B. E., Cloney, M. B., Sonabend, A., Showers, C., Ebiana, V., Nazarian, M., Swanson, K. R., Baldock, A., Brem, H., Bruce, J. N., Butler, W., Cahill, D. P., Carter, B., Orringer, D. A., Roberts, D. W., Sagher, O., Sanai, N., Schwartz, T. H., Silbergeld, D. L. & 4 others, Sisti, M. B., Thompson, R. C., Waziri, A. E. & McKhann, G., Aug 4 2016, (Accepted/In press) In : Neurosurgery.

Research output: Contribution to journalArticle

Glioblastoma
Crowdsourcing
Communication
Clinical Trials
National Institutes of Health (U.S.)

Establishment and biological characterization of a panel of glioblastoma multiforme (GBM) and GBM variant oncosphere cell lines

Binder, Z. A., Wilson, K. M., Salmasi, V., Orr, B. A., Eberhart, C. G., Siu, I. M., Lim, M., Weingart, J. D., Quinones-Hinojosa, A., Bettegowda, C., Kassam, A. B., Olivi, A., Brem, H., Riggins, G. J. & Gallia, G. L., Mar 1 2016, In : PLoS One. 11, 3, e0150271.

Research output: Contribution to journalArticle

oncospheres
Glioblastoma
Tumors
Cells
cell lines

Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours

Nailor, A., Walker, D. A., Jacques, T. S., Warren, K. E., Brem, H., Kearns, P. R., Greenwood, J., Penny, J. I., Pilkington, G. J., Carcaboso, A. M., Fleischhack, G., Macarthur, D., Slavc, I., Meijer, L., Gill, S., Lowis, S., Van Vuurden, D. G., Pearl, M., Clifford, S. C., Morrissy, S. & 8 others, Ivanov, D. P., Beccaria, K., Gilbertson, R. J., Straathof, K., Green, J., Smith, S., Rahman, R. & Kilday, J. P., Mar 31 2016, In : ecancermedicalscience. 10, 630.

Research output: Contribution to journalArticle

Brain Neoplasms
Pediatrics
Education
Pharmaceutical Preparations
Charities

Non-virally engineered human adipose mesenchymal stem cells produce BMP4, target brain tumors, and extend survival

Mangraviti, A., Tzeng, S., Gullotti, D., Kozielski, K. L., Kim, J. E., Seng, M., Abbadi, S., Schiapparelli, P., Sarabia-Estrada, R., Vescovi, A., Brem, H., Olivi, A., Tyler, B. M., Green, J. & Quinones-Hinojosa, A., Sep 1 2016, In : Biomaterials. 100, p. 53-66 14 p.

Research output: Contribution to journalArticle

Bone Morphogenetic Protein 4
Stem cells
Mesenchymal Stromal Cells
Brain Neoplasms
Tumors

Polylactic acid (PLA) controlled delivery carriers for biomedical applications

Tyler, B. M., Gullotti, D., Mangraviti, A., Utsuki, T. & Brem, H., Apr 25 2016, (Accepted/In press) In : Advanced Drug Delivery Reviews.

Research output: Contribution to journalArticle

Nanoparticles
Biomedical Engineering
Dendrimers
Drug Carriers
Poisons

Surgical complications following malignant brain tumor surgery: An analysis of 2002-2011 data

De La Garza-Ramos, R., Kerezoudis, P., Tamargo, R. J., Brem, H., Huang, J. & Bydon, M., Jan 1 2016, In : Clinical Neurology and Neurosurgery. 140, p. 6-10 5 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Hospital Mortality
Stroke
Odds Ratio
Hematoma

Syndrome of the Trephined: A Systematic Review

Ashayeri, K., Jackson, E., Huang, J., Brem, H. & Gordon, C. R., Oct 1 2016, In : Neurosurgery. 79, 4, p. 525-533 9 p.

Research output: Contribution to journalArticle

Language
Skin
Activities of Daily Living
PubMed
MEDLINE

Synthesis, characterization, and self-assembly with plasmid DNA of a quaternary ammonium derivative of pectic galactan and its fluorescent labeling for bioimaging applications

Chintakunta, R., Buaron, N., Kahn, N., Moriah, A., Lifshiz, R., Goldbart, R., Traitel, T., Tyler, B. M., Brem, H. & Kost, J., Oct 5 2016, In : Carbohydrate Polymers. 150, p. 308-318 11 p.

Research output: Contribution to journalArticle

Galactans
Ammonium Compounds
Self assembly
Labeling
Plasmids

Systemic tolerance mediated by melanoma brain tumors is reversible by radiotherapy and vaccination

Jackson, C. M., Kochel, C. M., Nirschl, C. J., Durham, N. M., Ruzevick, J., Alme, A., Francica, B. J., Elias, J., Daniels, A., Dubensky, T. W., Lauer, P., Brockstedt, D. G., Baxi, E. G., Calabresi, P., Taube, J. M., Pardo-Villamizar, C. A., Brem, H., Pardoll, A. M., Lim, M. & Drake, C. G., Mar 1 2016, In : Clinical Cancer Research. 22, 5, p. 1161-1172 12 p.

Research output: Contribution to journalArticle

Central Nervous System Neoplasms
Brain Neoplasms
Melanoma
Vaccination
Radiotherapy

The effect of regadenoson-induced transient disruption of the blood–brain barrier on temozolomide delivery to normal rat brain

Jackson, S., Anders, N., Mangraviti, A., Wanjiku, T. M., Sankey, E. W., Liu, A., Brem, H., Tyler, B. M., Rudek-Renaut, M. & Grossman, S. A., Feb 1 2016, In : Journal of Neuro-Oncology. 126, 3, p. 433-439 7 p.

Research output: Contribution to journalArticle

temozolomide
Brain
Rodentia
Purinergic P1 Receptor Agonists
Central Nervous System Agents