Henry Brem

Research output

Research output per year 1974 1992 1994 1995 1996 1998 2002 2003 2004 2005 2011 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2024

• 347 Article
• 47 Review article
• 15 Comment/debate
• 10 Chapter
• 17 More
  • 6 Conference contribution
  • 5 Editorial
  • 4 Letter
  • 1 Conference article
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2024

  GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment

  Williams, C. H., Neitzel, L. R., Cornell, J., Rea, S., Mills, I., Silver, M. S., Ahmad, J. D., Birukov, K. G., Birukova, A., Brem, H., Tyler, B., Bar, E. E. & Hong, C. C., Dec 2024, In: Experimental Hematology and Oncology. 13, 1, 13.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glioblastoma 100%
  • Ferroptosis 45%
  • Cell Death 21%
  • Tumor Microenvironment 15%
  • Zebrafish 14%

• The Hospital Frailty Risk Score Independently Predicts Postoperative Outcomes in Glioblastoma Patients

  Jimenez, A. E., Chakravarti, S., Liu, J., Kazemi, F., Jackson, C., Gallia, G., Bettegowda, C., Weingart, J., Brem, H. & Mukherjee, D., Mar 2024, In: World neurosurgery. 183, p. e747-e760

  Research output: Contribution to journal › Article › peer-review

  • Frailty 100%
  • Glioblastoma 86%
  • Patient Readmission 27%
  • Anesthesiologists 16%
  • International Classification of Diseases 16%
• 2023

  An asynchronous web-based intervention for neurosurgery residents to improve education on cost-effective care

  Khalafallah, A. M., Chakravarti, S., Cicalese, K. V., Porras, J. L., Kuo, C. C., Jimenez, A. E., Brem, H., Witham, T., Huang, J. & Mukherjee, D., Sep 2023, In: Clinical Neurology and Neurosurgery. 232, 107887.

  Research output: Contribution to journal › Article › peer-review

  • Internet-Based Intervention 100%
  • Neurosurgery 81%
  • Education 47%
  • Costs and Cost Analysis 46%
  • Operating Rooms 38%

• Deoxyhypusine hydroxylase: A novel therapeutic target differentially expressed in short-term vs long-term survivors of glioblastoma

  Ofek, P., Yeini, E., Arad, G., Danilevsky, A., Pozzi, S., Luna, C. B., Dangoor, S. I., Grossman, R., Ram, Z., Shomron, N., Brem, H., Hyde, T. M., Geiger, T. & Satchi-Fainaro, R., Aug 1 2023, In: International Journal of Cancer. 153, 3, p. 654-668 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • deoxyhypusine hydroxylase 100%
  • Glioblastoma 49%
  • Survivors 43%
  • hypusine 12%
  • eukaryotic translation initiation factor 5A 12%

• Establishing proof of concept for sonolucent cranioplasty and point of care ultrasound imaging after posterior fossa decompression for Chiari malformation

  Lee, R. P., Antar, A., Guryildirim, M., Brem, H., Luciano, M. & Huang, J., Jul 2023, In: Journal of Clinical Neuroscience. 113, p. 38-44 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Point-of-Care Systems 100%
  • Decompression 88%
  • Ultrasonography 68%
  • Radiation 33%
  • Surgical Wound Infection 24%

• First Experience with Postoperative Transcranial Ultrasound Through Sonolucent Burr Hole Covers in Adult Hydrocephalus Patients

  Meggyesy, M., Ahn, J., Ritter, C., Suk, I., Machnitz, A. J., Huang, J., Gordon, C., Brem, H. & Luciano, M., Feb 1 2023, In: Neurosurgery. 92, 2, p. 382-390 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydrocephalus 100%
  • Cerebrospinal Fluid 35%
  • Tomography 27%
  • Magnetic Resonance Imaging 27%
  • Radiation 20%

• Management and Molecular Characterization of Intraventricular Glioblastoma: A Single-Institution Case Series

  Parker, M., Kalluri, A., Materi, J., Gujar, S. K., Schreck, K., Mukherjee, D., Weingart, J., Brem, H., Redmond, K. J., Lucas, C. H. G., Bettegowda, C. & Rincon-Torroella, J., Sep 2023, In: International journal of molecular sciences. 24, 17, 13285.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Intraventricular 100%
  • Tumors 59%
  • Glioblastoma 57%
  • Chromosomes 33%
  • characterization 32%

• Patient Safety Indicator 04 Does Not Consistently Identify Failure to Rescue in the Neurosurgical Population

  Azad, T. D., Rodriguez, E., Raj, D., Xia, Y., Materi, J., Rincon-Torroella, J., Gonzalez, L. F., Suarez, J. I., Tamargo, R. J., Brem, H., Haut, E. R. & Bettegowda, C., Feb 1 2023, In: Neurosurgery. 92, 2, p. 338-343 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Patient Safety 100%
  • Population 39%
  • Neurosurgery 17%
  • Operating Rooms 16%
  • Mortality 15%

• Predictors of surgical site infection in glioblastoma patients undergoing craniotomy for tumor resection

  Nair, S. K., Botros, D., Chakravarti, S., Mao, Y., Wu, E., Lu, B., Liu, S., Elshareif, M., Jackson, C. M., Gallia, G. L., Bettegowda, C., Weingart, J., Brem, H. & Mukherjee, D., May 2023, In: Journal of neurosurgery. 138, 5, p. 1227-1234 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Surgical Wound Infection 100%
  • Craniotomy 97%
  • Glioblastoma 87%
  • Scalp 40%
  • Karnofsky Performance Status 31%

• Recruitment of women in neurosurgery: a 7-year quantitative analysis

  Feghali, J., Antar, A., Wicks, E. E., Sattari, S. A., Li, S., Witham, T. F., Brem, H. & Huang, J., Jan 2023, In: Journal of neurosurgery. 138, 1, p. 251-260 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neurosurgery 100%
  • Medical Schools 47%
  • Bibliometrics 12%
  • Graduate Medical Education 12%
  • Accreditation 10%

• Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative treatment of glioblastoma

  Wang, F., Huang, Q., Su, H., Sun, M., Wang, Z., Chen, Z., Zheng, M., Chakroun, R. W., Monroe, M. K., Chen, D., Wang, Z., Gorelick, N., Serra, R., Wang, H., Guan, Y., Suk, J. S., Tyler, B., Brem, H., Hanes, J. & Cui, H., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 118, e2204621120.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Paclitaxel 100%
  • Glioblastoma 97%
  • Hydrogels 79%
  • Macrophages 69%
  • T-Lymphocytes 45%

• The mFI-5 and Postoperative Outcomes in Brain Tumor Patients: A Bayesian Approach to Quantifying Uncertainty

  Jimenez, A. E., Porras, J. L., Azad, T. D., Luksik, A. S., Jackson, C., Bettegowda, C., Weingart, J., Brem, H. & Mukherjee, D., Sep 2023, In: World neurosurgery. 177, p. e716-e731

  Research output: Contribution to journal › Article › peer-review

  • Bayes Theorem 100%
  • Brain Neoplasms 76%
  • Uncertainty 75%
  • Odds Ratio 35%
  • Frailty 31%
• 2022

  Automatic detection of foreign body objects in neurosurgery using a deep learning approach on intraoperative ultrasound images: From animal models to first in-human testing

  Abramson, H. G., Curry, E. J., Mess, G., Thombre, R., Kempski-Leadingham, K. M., Mistry, S., Somanathan, S., Roy, L., Abu-Bonsrah, N., Coles, G., Doloff, J. C., Brem, H., Theodore, N., Huang, J. & Manbachi, A., Nov 30 2022, In: Frontiers in Surgery. 9, 1040066.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Deep Learning 100%
  • Neurosurgery 79%
  • Foreign Bodies 76%
  • Animal Models 52%
  • Brain 23%

• Clinical features and surgical outcomes of intracranial and spinal cord subependymomas

  Rincon-Torroella, J., Rakovec, M., Khalafallah, A. M., Liu, A., Bettegowda, A., Kut, C., Rodriguez, F. J., Weingart, J., Luciano, M., Olivi, A., Jallo, G. I., Brem, H., Mukherjee, D., Lim, M. & Bettegowda, C., Oct 2022, In: Journal of neurosurgery. 137, 4, p. 931-942 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Subependymal Glioma 100%
  • Spinal Cord 48%
  • Ependymoma 9%
  • Neoplasms 8%
  • Systematic Reviews 8%

• Combined intracranial Acriflavine, temozolomide and radiation extends survival in a rat glioma model

  Serra, R., Mangraviti, A., Gorelick, N. L., Shapira-Furman, T., Alomari, S., Cecia, A., Darjee, N., Brem, H., Rottenberg, Y., Domb, A. J. & Tyler, B., Jan 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 170, p. 179-186 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Acriflavine 100%
  • Intracranial 96%
  • Temozolomide 74%
  • Glioma 55%
  • Radiation 45%

• Cranioplasty Outcomes from 500 Consecutive Neuroplastic Surgery Patients

  Belzberg, M., Mitchell, K. A., Ben-Shalom, N., Asemota, A. O., Wolff, A. Y., Santiago, G. F., Shay, T., Huang, J., Manson, P. N., Brem, H. & Gordon, C. R., Sep 1 2022, In: Journal of Craniofacial Surgery. 33, 6, p. 1648-1654 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Reoperation 100%
  • Scalp 54%
  • Skull 53%
  • Hydrocephalus 28%
  • Hematoma 25%

• Cranioplasty with Customized Craniofacial Implants and Intraoperative Resizing for Single-Stage Reconstruction Following Oncologic Resection of Skull Neoplasms

  Ben-Shalom, N., Asemota, A. O., Beizberg, M., Harnof, S., Huang, J., Lim, M., Brem, H. & Gordon, C., Sep 1 2022, In: Journal of Craniofacial Surgery. 33, 6, p. 1641-1647 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Skull Neoplasms 100%
  • Biocompatible Materials 19%
  • Skull 18%
  • Computer-Aided Design 12%
  • Bone Neoplasms 11%

• DESIGNING A MURINE MODEL OF HUMAN GLIOBLASTOMA BRAIN TUMOR: DEVELOPMENT OF A PLATFORM FOR VALIDATION USING ULTRASOUND ELASTOGRAPHY

  Mess, G., Thombre, R., Kerensky, M., Curry, E., Abhabaglou, F., Alomari, S., Brem, H., Theodore, N., Tyler, B. & Manbachi, A., 2022, Proceedings of the 2022 Design of Medical Devices Conference, DMD 2022. American Society of Mechanical Engineers, V001T08A001. (Proceedings of the 2022 Design of Medical Devices Conference, DMD 2022).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Elasticity Imaging Techniques 100%
  • Tumors 83%
  • Glioblastoma 81%
  • Brain Neoplasms 76%
  • Ultrasonics 69%

• Home Program Matching in Neurosurgical Residency Programs: A 7-Year Study

  Antar, A., Feghali, J., Yang, W., Wicks, E. E., Sattari, S. A., Li, S., Witham, T. F., Brem, H. & Huang, J., Aug 2022, In: World neurosurgery. 164, p. e772-e783

  Research output: Contribution to journal › Article › peer-review

  • Internship and Residency 100%
  • Medical Schools 66%
  • Bibliometrics 44%
  • Accreditation 37%
  • Neurosurgery 35%

• Impact of international research fellows in neurosurgery: results from a single academic center

  Yang, W., Rincon-Torroella, J., Feghali, J., Khalafallah, A. M., Ishida, W., Perdomo-Pantoja, A., Quinones-Hinojosa, A., Lim, M., Gallia, G. L., Riggins, G. J., Anderson, W. S., Lo, S., Rigamonti, D., Tamargo, R. J., Witham, T. F., Bydon, A., Cohen, A. R., Jallo, G. I., Latremoliere, A., Luciano, M. G., & 8 othersMukherjee, D., Olivi, A., Qu, L., Gokaslan, Z. L., Sciubba, D., Tyler, B., Brem, H. & Huang, J., Jan 2022, In: Journal of neurosurgery. 136, 1, p. 295-305 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neurosurgery 100%
  • Medicine 66%
  • Publications 63%
  • Journal Impact Factor 45%
  • Students 32%

• Impact of virtual vs. in-person interviews among neurosurgery residency applicants

  Alomari, S., Lubelski, D., Feghali, J., Brem, H., Witham, T. & Huang, J., Jul 2022, In: Journal of Clinical Neuroscience. 101, p. 63-66 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neurosurgery 100%
  • Internship and Residency 94%
  • Interviews 60%
  • Surgical Specialties 12%
  • Medicine 6%

• Implementation of Minimally Invasive Brain Tumor Resection in Rodents for High Viability Tissue Collection

  Alomari, S., Kedda, J., Malla, A. P., Pacis, V., Anastasiadis, P., Xu, S., McFarland, E., Sukhon, L., Gallo, B., Rincon-Torroella, J., Ben-Shalom, N., Ames, H. M., Brem, H., Woodworth, G. F. & Tyler, B., May 2022, In: Journal of Visualized Experiments. 2022, 183, e64048.

  Research output: Contribution to journal › Article › peer-review

  • Tissue Survival 100%
  • Tumors 79%
  • Brain Neoplasms 72%
  • Tissue 65%
  • Rodentia 64%

• MCP-1/CCR2 axis inhibition sensitizes the brain microenvironment against melanoma brain metastasis progression

  Pozzi, S., Scomparin, A., Ben-Shushan, D., Yeini, E., Ofek, P., Nahmad, A. D., Soffer, S., Ionescu, A., Ruggiero, A., Barzel, A., Brem, H., Hyde, T. M., Barshack, I., Sinha, S., Ruppin, E., Weiss, T., Madi, A., Perlson, E., Slutsky, I., Florindo, H. F., & 1 othersSatchi-Fainaro, R., Sep 8 2022, In: JCI Insight. 7, 17, e154804.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chemokine CCL2 100%
  • Melanoma 74%
  • Neoplasm Metastasis 55%
  • Brain 44%
  • Astrocytes 18%

• Predicting High-Value Care Outcomes After Surgery for Non–Skull Base Meningiomas

  Jimenez, A. E., Chakravarti, S., Liu, S., Wu, E., Wei, O., Shah, P. P., Nair, S., Gendreau, J. L., Porras, J. L., Azad, T. D., Jackson, C. M., Gallia, G., Bettegowda, C., Weingart, J., Brem, H. & Mukherjee, D., Mar 2022, In: World neurosurgery. 159, p. e130-e138

  Research output: Contribution to journal › Article › peer-review

  • Meningioma 100%
  • Patient Readmission 42%
  • Length of Stay 42%
  • Multivariate Analysis 26%
  • Logistic Models 24%

• Predictors and Impact of Postoperative 30-Day Readmission in Glioblastoma

  Botros, D., Khalafallah, A. M., Huq, S., Dux, H., Oliveira, L. A. P., Pellegrino, R., Jackson, C., Gallia, G. L., Bettegowda, C., Lim, M., Weingart, J., Brem, H. & Mukherjee, D., Sep 1 2022, In: Neurosurgery. 91, 3, p. 477-484 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Patient Readmission 100%
  • Glioblastoma 85%
  • Karnofsky Performance Status 27%
  • Odds Ratio 20%
  • Frailty 12%

• Reexamining the Role of Postoperative ICU Admission for Patients Undergoing Elective Craniotomy: A Systematic Review

  Azad, T. D., Shah, P. P., Kannapadi, N. V., Rincon-Torroella, J., Xia, Y., Bernhardt, L. J., Hansen, L. J., Materi, J., Raj, D., Jackson, C. M., Mukherjee, D., Gallia, G. L., Weingart, J., Suarez, J. I., Brem, H. & Bettegowda, C., Sep 1 2022, In: Critical care medicine. 50, 9, p. 1380-1393 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Postoperative Care 100%
  • Patient Admission 94%
  • Craniotomy 94%
  • Systematic Reviews 63%
  • Databases 25%

• Synergy between glutamate modulation and anti-programmed cell death protein 1 immunotherapy for glioblastoma

  Medikonda, R., Choi, J., Pant, A., Saleh, L., Routkevitch, D., Tong, L., Belcaid, Z., Kim, Y. H., Jackson, C. M., Jackson, C., Mathios, D., Xia, Y., Shah, P. P., Patel, K., Kim, T., Srivastava, S., Huq, S., Ehresman, J., Pennington, Z., Tyler, B., & 2 othersBrem, H. & Lim, M., Feb 2022, In: Journal of neurosurgery. 136, 2, p. 379-388 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Programmed Cell Death 1 Receptor 100%
  • Glioblastoma 68%
  • Immunotherapy 61%
  • Glutamic Acid 61%
  • Tumor Microenvironment 31%

• The role of anticoagulation for superior sagittal sinus thrombosis following craniotomy for resection of parasagittal/parafalcine meningiomas

  Jimenez, A. E., Khalafallah, A. M., Botros, D., Horowitz, M. A., Azmeh, O., Lam, S., Oliveira, L. A. P., Chakravarti, S., Liu, S., Wu, E., Wei, O., Porras, J. L., Bettegowda, C., Tamargo, R. J., Brem, H. & Mukherjee, D., Jan 2022, In: Journal of neuro-oncology. 156, 2, p. 341-352 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Sagittal Sinus Thrombosis 100%
  • Superior Sagittal Sinus 85%
  • Craniotomy 66%
  • Meningioma 65%
  • Multivariate Analysis 9%

• The safety and efficacy of dexamethasone in the perioperative management of glioma patients

  Medikonda, R., Patel, K., Jackson, C., Saleh, L., Srivastava, S., Feghali, J., Mohan, A., Pant, A., Jackson, C. M., Weingart, J., Mukherjee, D., Bettegowda, C., Gallia, G. L., Brem, H. & Lim, M., Apr 2022, In: Journal of neurosurgery. 136, 4, p. 1062-1069 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Glioma 100%
  • Dexamethasone 99%
  • Safety 63%
  • Surgical Wound Infection 30%
  • Cohort Studies 18%

• Which medical schools produce the most neurosurgery residents? An analysis of the 2014-2020 cohort

  Antar, A., Feghali, J., Wicks, E. E., Sattari, S. A., Li, S., Witham, T. F., Brem, H. & Huang, J., Jul 2022, In: Journal of neurosurgery. 137, 1, p. 283-295 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurosurgery 100%
  • Medical Schools 95%
  • Public Opinion 17%
  • Bibliometrics 9%
  • Graduate Medical Education 8%
• 2021

  Automatic detection of cotton balls during brain surgery: Where deep learning meets ultrasound imaging to tackle foreign objects

  Mahapatra, S., Balamurugan, M., Chung, K., Kuppoor, V., Curry, E., Aghabaglau, F., Kaovasia, T. P., Acord, M., Ainechi, A., Kim, J. H., Tshey, Y., Ghinda, C. D., Son, J. K., Pustavoitau, A., Tyler, B., Robinson, S. D., Theodore, N., Brem, H., Huang, J. & Manbachi, A., 2021, Medical Imaging 2021: Ultrasonic Imaging and Tomography. Byram, B. C. & Ruiter, N. V. (eds.). SPIE, 116021C. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11602).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Deep Learning 100%
  • cotton 87%
  • Cotton 84%
  • surgery 81%
  • learning 78%

• Captopril inhibits Matrix Metalloproteinase-2 and extends survival as a temozolomide adjuvant in an intracranial gliosarcoma model

  Pinheiro, L., Perdomo-Pantoja, A., Casaos, J., Huq, S., Paldor, I., Vigilar, V., Mangraviti, A., Wang, Y., Witham, T. F., Brem, H. & Tyler, B., Aug 2021, In: Clinical Neurology and Neurosurgery. 207, 106771.

  Research output: Contribution to journal › Article › peer-review

  • Gliosarcoma 100%
  • Temozolomide 81%
  • Captopril 76%
  • Matrix Metalloproteinase 2 71%
  • Cell Movement 8%

• Combination checkpoint therapy with anti-PD-1 and anti-BTLA results in a synergistic therapeutic effect against murine glioblastoma

  Choi, J., Medikonda, R., Saleh, L., Kim, T., Pant, A., Srivastava, S., Kim, Y. H., Jackson, C., Tong, L., Routkevitch, D., Jackson, C., Mathios, D., Zhao, T., Cho, H., Brem, H. & Lim, M., 2021, In: OncoImmunology. 10, 1, 1956142.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Programmed Cell Death 1 Receptor 100%
  • Glioblastoma 68%
  • Therapeutic Uses 57%
  • T-Lymphocytes 43%
  • Regulatory T-Lymphocytes 20%

• Development of new brain metastases in triple negative breast cancer

  Medikonda, R., Srivastava, S., Kim, T., Xia, Y., Kim, J., Jackson, C., Weingart, J., Mukherjee, D., Bettegowda, C., Gallia, G., Brem, H., Redmond, K., Stearns, V., Kleinberg, L. & Lim, M., Apr 2021, In: Journal of neuro-oncology. 152, 2, p. 333-338 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Triple Negative Breast Neoplasms 100%
  • Neoplasm Metastasis 51%
  • Brain 40%
  • Breast Neoplasms 12%
  • Neuroimaging 11%

• Disulfiram and copper combination therapy targets NPL4, cancer stem cells and extends survival in a medulloblastoma model

  Serra, R., Zhao, T., Huq, S., Gorelick, N. L., Casaos, J., Cecia, A., Mangraviti, A., Eberhart, C., Bai, R., Olivi, A., Brem, H., Jackson, E. M. & Tyler, B., Nov 2021, In: PloS one. 16, 11 November, e0251957.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Disulfiram 100%
  • Medulloblastoma 87%
  • Neoplastic Stem Cells 75%
  • Nuclear Proteins 74%
  • Copper 71%

• Geographic Variation in Costs of Transsphenoidal Pituitary Surgery in the United States

  Asemota, A. O., Ishii, M., Brem, H. & Gallia, G. L., May 2021, In: World neurosurgery. 149, p. e1180-e1198

  Research output: Contribution to journal › Article › peer-review

  • Health Expenditures 100%
  • Costs and Cost Analysis 61%
  • Physicians 51%
  • Surgical Specialties 22%
  • Risk Adjustment 21%
  2 Scopus citations

• Impact of master’s degree attainment upon academic career placement in neurosurgery

  Khalafallah, A. M., Jimenez, A. E., Tamargo, R. J., Witham, T., Huang, J., Brem, H. & Mukherjee, D., Jan 2021, In: Journal of neurosurgery. 134, 1, p. 295-303 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurosurgery 100%
  • Internship and Residency 94%
  • Neurosurgeons 45%
  • Public Health 27%
  • Multivariate Analysis 18%
  4 Scopus citations

• Letter: Commentary: Costs and Their Predictors in Transsphenoidal Pituitary Surgery

  Asemota, A. O., Ishii, M., Brem, H. & Gallia, G. L., May 1 2021, In: Neurosurgery. 88, 5, p. E482-E483

  Research output: Contribution to journal › Letter › peer-review

  Open Access

• Mebendazole and temozolomide in patients with newly diagnosed high-grade gliomas: Results of a phase 1 clinical trial

  Gallia, G. L., Holdhoff, M., Brem, H., Joshi, A. D., Hann, C. L., Bai, R. Y., Staedtke, V., Blakeley, J. O., Sengupta, S., Jarrell, T. C., Wollett, J., Szajna, K., Helie, N., Mattox, A. K., Ye, X., Rudek, M. A. & Riggins, G. J., Jan 1 2021, In: Neuro-Oncology Advances. 3, 1, vdaa154.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mebendazole 100%
  • Temozolomide 83%
  • Clinical Trials, Phase I 81%
  • Glioma 62%
  • Glioblastoma 13%

• Patient-Specific Factors Drive Intensive Care Unit and Total Hospital Length of Stay in Operative Patients with Brain Tumor

  Jimenez, A. E., Shah, P. P., Khalafallah, A. M., Huq, S., Porras, J. L., Jackson, C. M., Gallia, G., Bettegowda, C., Weingart, J., Suarez, J. I., Brem, H. & Mukherjee, D., Sep 2021, In: World neurosurgery. 153, p. e338-e348

  Research output: Contribution to journal › Article › peer-review

  • Brain Neoplasms 100%
  • Intensive Care Units 89%
  • Length of Stay 81%
  • Frailty 18%
  • Linear Models 12%

• PD-1+ Monocytes Mediate Cerebral Vasospasm following Subarachnoid Hemorrhage

  Jackson, C. M., Choi, J., Routkevitch, D., Pant, A., Saleh, L., Ye, X., Caplan, J. M., Huang, J., McDougall, C. G., Pardoll, D. M., Brem, H., Tamargo, R. J. & Lim, M., Apr 1 2021, In: Neurosurgery. 88, 4, p. 855-863 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Intracranial Vasospasm 100%
  • Subarachnoid Hemorrhage 78%
  • Monocytes 62%
  • Ruptured Aneurysm 18%
  • Internal Carotid Artery 16%
  1 Scopus citations

• Pectic Galactan Polysaccharide-Based Gene Delivery System for Targeting Neuroinflammation

  Buaron, N., Mangraviti, A., Volpin, F., Liu, A., Pedone, M., Sankey, E., Aranovich, D., Adar, I., Rodriguez, F. J., Nyska, A., Goldbart, R., Traitel, T., Brem, H., Tyler, B. & Kost, J., Oct 26 2021, In: Advanced Functional Materials. 31, 44, 2100643.

  Research output: Contribution to journal › Article › peer-review

  • Galactans 100%
  • Galactan 63%
  • Polysaccharides 62%
  • polysaccharides 57%
  • genes 49%

• Preclinical efficacy of ribavirin in SHH and group 3 medulloblastoma

  Huq, S., Kannapadi, N. V., Casaos, J., Lott, T., Felder, R., Serra, R., Gorelick, N. L., Ruiz-Cardozo, M. A., Ding, A. S., Cecia, A., Medikonda, R., Ehresman, J., Brem, H., Skuli, N. & Tyler, B. M., Apr 2021, In: Journal of Neurosurgery: Pediatrics. 27, 4, p. 482-488 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hedgehog Proteins 100%
  • Medulloblastoma 96%
  • Ribavirin 89%
  • Enhancer of Zeste Homolog 2 Protein 36%
  • Eukaryotic Initiation Factor-4E 35%

• Predictors of Academic Neurosurgical Career Trajectory among International Medical Graduates Training within the United States

  Khalafallah, A. M., Jimenez, A. E., Camp, S., Horowitz, M. A., Chiu, I., Ryu, D., Charewycz, N., Vera, L., Bhoopalam, M., Feghali, J., Sharma, M., Lubelski, D., Cohen, A. R., Tamargo, R. J., Witham, T., Huang, J., Brem, H. & Mukherjee, D., Sep 1 2021, In: Neurosurgery. 89, 3, p. 478-485 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Internship and Residency 100%
  • Medical Schools 40%
  • Neurosurgeons 33%
  • Neurosurgery 31%
  • Graduate Medical Education 12%

• P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression

  Yeini, E., Ofek, P., Pozzi, S., Albeck, N., Ben-Shushan, D., Tiram, G., Golan, S., Kleiner, R., Sheinin, R., Israeli Dangoor, S., Reich-Zeliger, S., Grossman, R., Ram, Z., Brem, H., Hyde, T. M., Magod, P., Friedmann-Morvinski, D., Madi, A. & Satchi-Fainaro, R., Dec 1 2021, In: Nature communications. 12, 1, 1912.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • macrophages 100%
  • P-Selectin 83%
  • progressions 77%
  • Microglia 70%
  • Glioblastoma 68%
  1 Scopus citations

• Quantifying the utility of a multidisciplinary neuro-oncology tumor board

  Khalafallah, A. M., Jimenez, A. E., Romo, C. G., Kamson, D. O., Kleinberg, L., Weingart, J., Brem, H., Grossman, S. A. & Mukherjee, D., Jul 2021, In: Journal of neurosurgery. 135, 1, p. 87-92 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Neoplasms 100%
  • Nervous System Neoplasms 97%
  • Referral and Consultation 50%
  • Glioblastoma 33%
  • Patient Care 26%

• Retraction: Mechanisms underlying the generation of autonomorespiratory coupling amongst the respiratory central pattern generator, sympathetic oscillators, and cardiovagal premotoneurons (Journal of Integrative Neuroscience (2020) 19 (521-560) DOI: 10.31083/j.jin.2020.03.0196)

  Journal of Integrative Neuroscience Editorial Office, Jun 30 2021, In: Journal of Integrative Neuroscience. 20, 2, p. 527 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Central Pattern Generators 100%
  • Neurosciences 72%
  • Sweden 66%
  • Names 64%

• Targeting of cyclin-dependent kinases in atypical teratoid rhabdoid tumors with multikinase inhibitor TG02

  Ding, A. S., Huq, S., Casaos, J., Raj, D., Morales, M., Zhao, T., Kim, T., Srivastava, S., Pant, A., Serra, R., Gorelick, N. L., Brem, H. & Tyler, B., Dec 2021, In: Journal of Neurosurgery: Pediatrics. 28, 6, p. 734-743 10 p.

  Research output: Contribution to journal › Article › peer-review

  • 14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene 100%
  • Typical Teratoid Rhabdoid Tumor 72%
  • Atypical Teratoid Tumor 72%
  • Cyclin-Dependent Kinases 53%
  • Enhancer of Zeste Homolog 2 Protein 10%

• The 5-factor modified frailty index: An effective predictor of mortality in brain tumor patients

  Khalafallah, A. M., Huq, S., Jimenez, A. E., Brem, H. & Mukherjee, D., Jul 2021, In: Journal of neurosurgery. 135, 1, p. 78-86 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Frailty 100%
  • Brain Neoplasms 81%
  • Comorbidity 68%
  • Mortality 44%
  • Statistics 28%

• The Impact of Hydrocephalus Shunt Devices on Quality of Life

  Mitchell, K. A. S., Zelko, I., Shay, T., Horen, S., Williams, A., Luciano, M., Huang, J., Brem, H. & Gordon, C. R., Jul 1 2021, In: Journal of Craniofacial Surgery. 32, 5, p. 1746-1750 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hydrocephalus 100%
  • Quality of Life 61%
  • Equipment and Supplies 56%
  • Reoperation 25%
  • Technology 17%