Heng Li

Associate Professor

20022020

Research output per year

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Research Output

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Article
2020

Anatomic change over the course of treatment for non-small cell lung cancer patients and its impact on intensity-modulated radiation therapy and passive-scattering proton therapy deliveries

Chen, M., Yang, J., Liao, Z., Chen, J., Xu, C., He, X., Zhang, X., Zhu, R. X. & Li, H., Mar 5 2020, In : Radiation Oncology. 15, 1, 55.

Research output: Contribution to journalArticle

Open Access

An improved method for analyzing and reporting patterns of in-field recurrence after stereotactic ablative radiotherapy in early-stage non-small cell lung cancer

Nantavithya, C., Gomez, D. R., Chang, J. Y., Mohamed, A. S. R., Fuller, C. D., Li, H., Brooks, E. D. & Gandhi, S. J., Apr 2020, In : Radiotherapy and Oncology. 145, p. 209-214 6 p.

Research output: Contribution to journalArticle

Open Access

Multiple-CT optimization: An adaptive optimization method to account for anatomical changes in intensity-modulated proton therapy for head and neck cancers

Yang, Z., Zhang, X., Wang, X., Zhu, X. R., Gunn, B., Frank, S. J., Chang, Y., Li, Q., Yang, K., Wu, G., Liao, L., Li, Y., Chen, M. & Li, H., Jan 2020, In : Radiotherapy and Oncology. 142, p. 124-132 9 p.

Research output: Contribution to journalArticle

Transitioning from measurement-based to combined patient-specific quality assurance for intensity-modulated proton therapy

Chen, M., Yepes, P., Hojo, Y., Poenisch, F., Li, Y., Chen, J., Xu, C., He, X., Gunn, G. B., Frank, S. J., Sahoo, N., Li, H., Zhu, X. R. & Zhang, X., Mar 1 2020, In : The British journal of radiology. 93, 1107, 1 p.

Research output: Contribution to journalArticle

2019

An analytical model for the upper bound estimation of respiratory motion–induced dose uncertainty in spot-scanning proton beam therapy

Li, H., Zhang, X., Li, Y. & Zhu, R. X., Nov 1 2019, In : Medical physics. 46, 11, p. 5249-5261 13 p.

Research output: Contribution to journalArticle

Effect of setup and inter-fraction anatomical changes on the accumulated dose in CT-guided breath-hold intensity modulated proton therapy of liver malignancies

Yang, Z., Chang, Y., Brock, K. K., Cazoulat, G., Koay, E. J., Koong, A. C., Herman, J., Park, P. C., Poenisch, F., Li, Q., Yang, K., Wu, G., Anderson, B., Ohrt, A. N., Li, Y., Zhu, X. R., Zhang, X. & Li, H., May 1 2019, In : Radiotherapy and Oncology. 134, p. 101-109 9 p.

Research output: Contribution to journalArticle

Effects of alterations in positron emission tomography imaging parameters on radiomics features

Ger, R. B., Meier, J. G., Pahlka, R. B., Gay, S., Mumme, R., Fuller, C. D., Li, H., Howell, R. M., Layman, R. R., Jason Stafford, R., Zhou, S., Mawlawi, O. & Court, L. E., 2019, In : PloS one. 14, 9, e0221877.

Research output: Contribution to journalArticle

Open Access

Radiomics features of the primary tumor fail to improve prediction of overall survival in large cohorts of CT- And PET-imaged head and neck cancer patients

Ger, R. B., Zhou, S., Elgohari, B., Elhalawani, H., Mackin, D. M., Meier, J. G., Nguyen, C. M., Anderson, B. M., Gay, C., Ning, J., Fuller, C. D., Li, H., Howell, R. M., Layman, R. R., Mawlawi, O., Stafford, R. J., Aerts, H. & Court, L. E., 2019, In : PloS one. 14, 9, e0222509.

Research output: Contribution to journalArticle

Open Access

Statistical evaluation of worst-case robust optimization intensity-modulated proton therapy plans using an exhaustive sampling approach

Yang, Z., Li, H., Li, Y., Li, Y., Chang, Y., Li, Q., Yang, K., Wu, G., Sahoo, N., Poenisch, F., Gillin, M., Zhu, X. R. & Zhang, X., Jul 19 2019, In : Radiation Oncology. 14, 1, 129.

Research output: Contribution to journalArticle

Open Access
2018

Comprehensive Investigation on Controlling for CT Imaging Variabilities in Radiomics Studies

Ger, R. B., Zhou, S., Chi, P. C. M., Lee, H. J., Layman, R. R., Jones, A. K., Goff, D. L., Fuller, C. D., Howell, R. M., Li, H., Stafford, R. J., Court, L. E. & Mackin, D. S., Dec 1 2018, In : Scientific reports. 8, 1, 13047.

Research output: Contribution to journalArticle

Open Access

Data descriptor: Dynamic contrastenhanced magnetic resonance imaging for head and neck cancers

Elhalawani, H., Ger, R. B., Mohamed, A. S. R., Awan, M. J., Ding, Y., Li, K., Fave, X. J., Beers, A. L., Driscoll, B., Hormuth, D. A., Van Houdt, P. J., He, R., Zhou, S., Mathieu, K. B., Li, H., Coolens, C., Chung, C., Bankson, J. A., Huang, W., Wang, J. & 12 others, Sandulache, V. C., Lai, S. Y., Howell, R. M., Stafford, R. J., Yankeelov, T. E., Van Der Heide, U. A., Frank, S. J., Barboriak, D. P., Hazle, J. D., Court, L. E., Kalpathy-Cramer, J. & Fuller, C. D., Feb 13 2018, In : Scientific Data. 5, 180008.

Research output: Contribution to journalArticle

Open Access

Multiple-CT optimization of intensity-modulated proton therapy – Is it possible to eliminate adaptive planning?

Wang, X., Li, H., Zhu, X. R., Hou, Q., Liao, L., Jiang, B., Li, Y., Wang, P., Lang, J. & Zhang, X., Jul 1 2018, In : Radiotherapy and Oncology. 128, 1, p. 167-173 7 p.

Research output: Contribution to journalArticle

Phase 2 Study of Stereotactic Body Radiation Therapy and Stereotactic Body Proton Therapy for High-Risk, Medically Inoperable, Early-Stage Non-Small Cell Lung Cancer

Nantavithya, C., Gomez, D. R., Wei, X., Komaki, R., Liao, Z., Lin, S. H., Jeter, M., Nguyen, Q. N., Li, H., Zhang, X., Poenisch, F., Zhu, X. R., Balter, P. A., Feng, L., Choi, N. C., Mohan, R. & Chang, J. Y., Jul 1 2018, In : International Journal of Radiation Oncology Biology Physics. 101, 3, p. 558-563 6 p.

Research output: Contribution to journalArticle

Practical guidelines for handling head and neck computed tomography artifacts for quantitative image analysis

Ger, R. B., Craft, D. F., Mackin, D. S., Zhou, S., Layman, R. R., Jones, A. K., Elhalawani, H., Fuller, C. D., Howell, R. M., Li, H., Stafford, R. J. & Court, L. E., Nov 1 2018, In : Computerized Medical Imaging and Graphics. 69, p. 134-139 6 p.

Research output: Contribution to journalArticle

Reirradiation of thoracic cancers with intensity modulated proton therapy

Ho, J. C., Nguyen, Q. N., Li, H., Allen, P. K., Zhang, X., Liao, Z., Zhu, X. R., Gomez, D., Lin, S. H., Gillin, M., Komaki, R., Hahn, S. & Chang, J. Y., Jan 1 2018, In : Practical Radiation Oncology. 8, 1, p. 58-65 8 p.

Research output: Contribution to journalArticle

Synthetic head and neck and phantom images for determining deformable image registration accuracy in magnetic resonance imaging

Ger, R. B., Yang, J., Ding, Y., Jacobsen, M. C., Cardenas, C. E., Fuller, C. D., Howell, R. M., Li, H., Stafford, R. J., Zhou, S. & Court, L. E., Sep 2018, In : Medical physics. 45, 9, p. 4315-4321 7 p.

Research output: Contribution to journalArticle

2017

Accuracy of deformable image registration on magnetic resonance images in digital and physical phantoms

Ger, R. B., Yang, J., Ding, Y., Jacobsen, M. C., Fuller, C. D., Howell, R. M., Li, H., Jason Stafford, R., Zhou, S. & Court, L. E., Oct 1 2017, In : Medical physics. 44, 10, p. 5153-5161 9 p.

Research output: Contribution to journalArticle

A Multi-Institutional Comparison of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Parameter Calculations

Ger, R. B., Mohamed, A. S. R., Awan, M. J., Ding, Y., Li, K., Fave, X. J., Beers, A. L., Driscoll, B., Elhalawani, H., Hormuth, D. A., Houdt, P. J. V., He, R., Zhou, S., Mathieu, K. B., Li, H., Coolens, C., Chung, C., Bankson, J. A., Huang, W., Wang, J. & 12 others, Sandulache, V. C., Lai, S. Y., Howell, R. M., Stafford, R. J., Yankeelov, T. E., Heide, U. A. V. D., Frank, S. J., Barboriak, D. P., Hazle, J. D., Court, L. E., Kalpathy-Cramer, J. & Fuller, C. D., Dec 1 2017, In : Scientific reports. 7, 1, 11185.

Research output: Contribution to journalArticle

Open Access

Clinical outcomes of intensity modulated proton therapy and concurrent chemotherapy in esophageal carcinoma: a single institutional experience

Prayongrat, A., Xu, C., Li, H. & Lin, S. H., Jul 1 2017, In : Advances in Radiation Oncology. 2, 3, p. 301-307 7 p.

Research output: Contribution to journalArticle

Open Access

Proton beam radiotherapy and concurrent chemotherapy for unresectable stage III non–small cell lung cancer: Final results of a phase 2 study

Chang, J. Y., Verma, V., Li, M., Zhang, W., Komaki, R., Lu, C., Allen, P. K., Liao, Z., Welsh, J., Lin, S. H., Gomez, D., Jeter, M., O'Reilly, M., Zhu, R. X., Zhang, X., Li, H., Mohan, R., Heymach, J. V., Vaporciyan, A. A., Hahn, S. & 1 others, Cox, J. D., Aug 1 2017, In : JAMA Oncology. 3, 8, e172032.

Research output: Contribution to journalArticle

Open Access

Synchrotron-based pencil beam scanning nozzle with an integrated mini-ridge filter: A dosimetric study to optimize treatment delivery

Wang, X., Li, Y., Zhang, X., Li, H., Miyazaki, K., Fujimoto, R., Akiyama, H., Gillin, M. T., Poenisch, F., Sahoo, N., Grosshans, D., Gunn, B., Frank, S. J., Wang, P., Lang, J., Hou, Q. & Zhu, X. R., Dec 13 2017, In : Cancers. 9, 12, 170.

Research output: Contribution to journalArticle

Open Access
2016

Motion-robust intensity-modulated proton therapy for distal esophageal cancer

Yu, J., Zhang, X., Liao, L., Li, H., Zhu, R., Park, P. C., Sahoo, N., Gillin, M., Li, Y., Chang, J. Y., Komaki, R. & Lin, S. H., Mar 1 2016, In : Medical physics. 43, 3, p. 1111-1118 8 p.

Research output: Contribution to journalArticle

Perturbation of water-equivalent thickness as a surrogate for respiratory motion in proton therapy

Matney, J. E., Park, P. C., Li, H., Court, L. E., Ron Zhu, X., Dong, L., Liu, W. & Mohan, R., Jan 1 2016, In : Journal of applied clinical medical physics. 17, 2, p. 368-378 11 p.

Research output: Contribution to journalArticle

Open Access
2015

Early experience with intensity modulated proton therapy for lung-intact mesothelioma: A case series

Pan, H. Y., Jiang, S., Sutton, J., Liao, Z., Chance, W. W., Frank, S. J., Zhu, X. R., Li, H., Fontanilla, H. P., Zhang, X. & Gomez, D. R., Jan 1 2015, In : Practical Radiation Oncology. 5, 4, p. e345-e353

Research output: Contribution to journalArticle

Impact of respiratory motion on worst-case scenario optimized intensity modulated proton therapy for lung cancers

Liu, W., Liao, Z., Schild, S. E., Liu, Z., Li, H., Li, Y., Park, P. C., Li, X., Stoker, J., Shen, J., Keole, S., Anand, A., Fatyga, M., Dong, L., Sahoo, N., Vora, S., Wong, W., Zhu, X. R., Bues, M. & Mohan, R., Mar 1 2015, In : Practical Radiation Oncology. 5, 2, p. e77-e86

Research output: Contribution to journalArticle

Is there a clinical benefit with a smooth compensator design compared with a plunged compensator design for passive scattered protons?

Tabibian, A. A., Powers, A., Dolormente, K., Oommen, S., Tiwari, A., Palmer, M., Zhu, X. R., Li, H., Sahoo, N., Wisdom, P., Velasco, K., Erhart, K., Stanley, H. & Nguyen, B. N. T., Feb 1 2015, In : Medical Dosimetry. 40, 1, p. 37-43 7 p.

Research output: Contribution to journalArticle

Robust optimization in intensity-modulated proton therapy to account for anatomy changes in lung cancer patients

Li, H., Zhang, X., Park, P., Liu, W., Chang, J., Liao, Z., Frank, S., Li, Y., Poenisch, F., Mohan, R., Gillin, M. & Zhu, R., Mar 1 2015, In : Radiotherapy and Oncology. 114, 3, p. 367-372 6 p.

Research output: Contribution to journalArticle

Selective robust optimization: A new intensity-modulated proton therapy optimization strategy

Li, Y., Niemela, P., Liao, L., Jiang, S., Li, H., Poenisch, F., Zhu, X. R., Siljamaki, S., Vanderstraeten, R., Sahoo, N., Gillin, M. & Zhang, X., Aug 1 2015, In : Medical physics. 42, 8, p. 4840-4847 8 p.

Research output: Contribution to journalArticle

2014

A single-field integrated boost treatment planning technique for spot scanning proton therapy

Zhu, X. R., Poenisch, F., Li, H., Zhang, X., Sahoo, N., Wu, R. Y., Li, X., Lee, A. K., Chang, E. L., Choi, S., Pugh, T., Frank, S. J., Gillin, M. T., Mahajan, A. & Grosshans, D. R., Sep 11 2014, In : Radiation Oncology. 9, 1, 202.

Research output: Contribution to journalArticle

Open Access

Clinical implementation of intensity modulated proton therapy for thoracic malignancies

Chang, J. Y., Li, H., Zhu, X. R., Liao, Z., Zhao, L., Liu, A., Li, Y., Sahoo, N., Poenisch, F., Gomez, D. R., Wu, R., Gillin, M. & Zhang, X., Nov 15 2014, In : International Journal of Radiation Oncology Biology Physics. 90, 4, p. 809-818 10 p.

Research output: Contribution to journalArticle

Dosimetric benefits of robust treatment planning for intensity modulated proton therapy for base-of-skull cancers

Liu, W., Mohan, R., Park, P., Liu, Z., Li, H., Li, X., Li, Y., Wu, R., Sahoo, N., Dong, L., Zhu, X. R. & Grosshans, D. R., Nov 1 2014, In : Practical Radiation Oncology. 4, 6, p. 384-391 8 p.

Research output: Contribution to journalArticle

Dosimetric effects caused by couch tops and immobilization devices: Report of AAPM Task Group 176

Olch, A. J., Gerig, L., Li, H., Mihaylov, I. & Morgan, A., Jun 2014, In : Medical physics. 41, 6, 061501.

Research output: Contribution to journalArticle

Evaluation and mitigation of the interplay effects of intensity modulated proton therapy for lung cancer in a clinical setting

Kardar, L., Li, Y., Li, X., Li, H., Cao, W., Chang, J. Y., Liao, L., Zhu, R. X., Sahoo, N., Gillin, M., Liao, Z., Komaki, R., Cox, J. D., Lim, G. & Zhang, X., Nov 1 2014, In : Practical Radiation Oncology. 4, 6, p. E259-E268

Research output: Contribution to journalArticle

Evaluation of the systematic error in using 3D dose calculation in scanning beam proton therapy for lung cancer

Li, H., Liu, W., Park, P., Matney, J., Liao, Z., Chang, J., Zhang, X., Li, Y. & Zhu, R. X., 2014, In : Journal of applied clinical medical physics. 15, 5, p. 47-56 10 p.

Research output: Contribution to journalArticle

Open Access

On the interplay effects with proton scanning beams in stage III lung cancer

Li, Y., Kardar, L., Li, X., Li, H., Cao, W., Chang, J. Y., Liao, L., Zhu, R. X., Sahoo, N., Gillin, M., Liao, Z., Komaki, R., Cox, J. D., Lim, G. & Zhang, X., Feb 2014, In : Medical physics. 41, 2, 021721.

Research output: Contribution to journalArticle

Proton energy optimization and reduction for intensity-modulated proton therapy

Cao, W., Lim, G., Liao, L., Li, Y., Jiang, S., Li, X., Li, H., Suzuki, K., Zhu, X. R., Gomez, D. & Zhang, X., Nov 7 2014, In : Physics in medicine and biology. 59, 21, p. 6341-6354 14 p., 6341.

Research output: Contribution to journalArticle

2013

Commissioning dose computation models for spot scanning proton beams in water for a commercially available treatment planning system

Zhu, X. R., Poenisch, F., Lii, M., Sawakuchi, G. O., Titt, U., Bues, M., Song, X., Zhang, X., Li, Y., Ciangaru, G., Li, H., Taylor, M. B., Suzuki, K., Mohan, R., Gillin, M. T. & Sahoo, N., Apr 2013, In : Medical physics. 40, 4, 041723.

Research output: Contribution to journalArticle

Effects of respiratory motion on passively scattered proton therapy versus intensity modulated photon therapy for stage III lung cancer: Are proton plans more sensitive to breathing motion?

Matney, J., Park, P. C., Bluett, J., Chen, Y. P., Liu, W., Court, L. E., Liao, Z., Li, H. & Mohan, R., Nov 1 2013, In : International Journal of Radiation Oncology Biology Physics. 87, 3, p. 576-582 7 p.

Research output: Contribution to journalArticle

Improving spot-scanning proton therapy patient specific quality assurance with HPlusQA, a second-check dose calculation engine

MacKin, D., Li, Y., Taylor, M. B., Kerr, M., Holmes, C., Sahoo, N., Poenisch, F., Li, H., Lii, J., Amos, R., Wu, R., Suzuki, K., Gillin, M. T., Zhu, X. R. & Zhang, X., Dec 2013, In : Medical physics. 40, 12, 121708.

Research output: Contribution to journalArticle

MO‐D‐108‐09: Perturbation of Tissue Density Is An Important Metric to Be Considered When Planning for Respiratory Motion Management for Lung Proton Therapy

Park, P., Matlney, J., Mohlan, R., Zlhu, X., Dong, L., li, H., Cheung, J., Sahoo, N., Yang, J., Poenisch, F. & Liu, W., Jun 2013, In : Medical physics. 40, 6, p. 397-398 2 p.

Research output: Contribution to journalArticle

MO‐F‐WAB‐04: Does a Threshold of Tumor Motion Exist to Indicate Respiratory Gating for Proton Therapy?

Matney, J., Bluett, J., Li, H., Court, L., Liao, Z. & Mohan, R., Jan 1 2013, In : Medical physics. 40, 6, 1 p.

Research output: Contribution to journalArticle

MO‐G‐137‐04: Using Molecular Dynamics Simulation Algorithm to Overcome the Local Minima of Gradient Methods in IMPT Treatment Plan Optimization

Liao, L., Cai, B., li, Y., Cao, W., Lim, G., Li, H. & Zhang, X., Jan 1 2013, In : Medical physics. 40, 6, 1 p.

Research output: Contribution to journalArticle

MO‐G‐137‐05: Improving Passive Scattering Proton Therapy Plan Quality by Optimizing Compensator Parameters

Taylor, M., Liao, Z., Bluett, J., Kerr, M., Li, H., Sahoo, N., Gillin, M., Zhu, X. & Zhang, X., Jan 1 2013, In : Medical physics. 40, 6, p. 416-417 2 p.

Research output: Contribution to journalArticle

Patient-specific quantification of respiratory Motion-induced dose uncertainty for Step-and-shoot IMRT of lung cancer

Li, H., Park, P., Liu, W., Matney, J., Liao, Z., Balter, P., Li, Y., Zhang, X., Li, X. & Zhu, X. R., Dec 2013, In : Medical physics. 40, 12, 121712.

Research output: Contribution to journalArticle

Statistical assessment of proton treatment plans under setup and range uncertainties

Park, P. C., Cheung, J. P., Zhu, X. R., Lee, A. K., Sahoo, N., Tucker, S. L., Liu, W., Li, H., Mohan, R., Court, L. E. & Dong, L., Aug 1 2013, In : International Journal of Radiation Oncology Biology Physics. 86, 5, p. 1007-1013 7 p.

Research output: Contribution to journalArticle

SU‐E‐T‐04: Application of a Semi‐Empirical Formula to Determine Spread Out Bragg Peak Factors and Range Shifter Factors From Measured Depth Dose Curves for Passively Scattered Proton Beams

Sahoo, N., Dhanesar, S., Poenisch, F., Lii, M., Li, H., Zhang, X., Amos, R., wu, R., Gillin, M. & Zhu, X., Jan 1 2013, In : Medical physics. 40, 6, p. 203-204 2 p.

Research output: Contribution to journalArticle

SU‐E‐T‐157: Improving Spot Scanning Proton Therapy Patient‐Specific Quality Assurance Through Early Application of Second‐Check Dose Calculation Software

Mackin, D., Zhang, X., li, Y., Taylor, M., Kerr, M., Holmes, C., Sahoo, N., Poenisch, F., Li, H., Lii, M., Amos, R., wu, R., Suzuki, K., Gillin, M. & Zhu, X., Jan 1 2013, In : Medical physics. 40, 6, 1 p.

Research output: Contribution to journalArticle

SU‐E‐T‐365: Respiratory Motion‐Induced Dose Uncertainty in Step‐And‐Shoot IMRT

Li, H., Park, P., Liu, W., Matney, J., Liao, Z., Zhang, X. & Zhu, X., Jan 1 2013, In : Medical physics. 40, 6, 1 p.

Research output: Contribution to journalArticle

SU‐E‐T‐471: Potential of Using Simultaneous Integrated Boost (SIB) to Significantly Improve the Normal Tissue Sparing For Advanced Staged Non‐Small Cell Lung Cancer(NSCLC)

Wang, X., Liao, L., Wang, H., li, H., li, Y., li, X., Quan, M., Liao, Z. & Zhang, X., Jun 2013, In : Medical physics. 40, 6, 1 p.

Research output: Contribution to journalArticle