Hariharan Easwaran

Assistant Professor

19992018
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Research Output 1999 2018

  • 32 Article
  • 2 Review article
  • 1 Conference contribution

A KDM5 inhibitor increases global H3K4 trimethylation occupancy and enhances the biological efficacy of 5-aza-2′-deoxycytidine

Leadem, B. R., Kagiampakis, I., Wilson, C., Cheung, T. K., Arnott, D., Trojer, P., Classon, M., Easwaran, H. & Baylin, S. B. Mar 1 2018 In : Cancer Research. 78, 5, p. 1127-1139 13 p.

Research output: Contribution to journalArticle

decitabine
Breast Neoplasms
Genes
Drug Combinations
Epigenomics

DNA Methylation Patterns Separate Senescence from Transformation Potential and Indicate Cancer Risk

Xie, W., Kagiampakis, I., Pan, L., Zhang, Y. W., Murphy, L., Tao, Y., Kong, X., Kang, B., Xia, L., Carvalho, F. L. F., Sen, S., Chiu Yen, R. W., Zahnow, C. A., Ahuja, N., Baylin, S. B. & Easwaran, H. Feb 12 2018 In : Cancer cell. 33, 2, p. 309-321.e5

Research output: Contribution to journalArticle

DNA Methylation
Methylation
Developmental Genes
Neoplasms
Epigenomics

Epigenetic regulation of gene expression in cancer: Techniques, resources and analysis

Kagohara, L. T., Stein-O'Brien, G. L., Kelley, D., Flam, E., Wick, H. C., Danilova, L. V., Easwaran, H., Favorov, A. V., Qian, J., Gaykalova, D. A. & Fertig, E. J. Jan 1 2018 In : Briefings in Functional Genomics. 17, 1, p. 49-63 15 p.

Research output: Contribution to journalReview article

Gene Expression Regulation
Bioinformatics
Epigenomics
Gene expression
Throughput

Acetylation Enhances TET2 Function in Protecting against Abnormal DNA Methylation during Oxidative Stress

Zhang, Y. W., Wang, Z., Xie, W., Cai, Y., Xia, L., Easwaran, H., Luo, J., Yen, R. W. C., Li, Y. & Baylin, S. B. Jan 19 2017 In : Molecular Cell. 65, 2, p. 323-335 13 p.

Research output: Contribution to journalArticle

DNA Methylation
Acetylation
Oxidative Stress
5-Methylcytosine
CpG Islands

Chronic Cigarette Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single-Step Transformation by KRAS Mutations

Vaz, M., Hwang, S. Y., Kagiampakis, I., Phallen, J., Patil, A., O'Hagan, H. M., Murphy, L., Zahnow, C. A., Gabrielson, E., Velculescu, V. E., Easwaran, H. P. & Baylin, S. B. Sep 11 2017 In : Cancer cell. 32, 3, p. 360-376 17 p.

Research output: Contribution to journalArticle

Oncogenes
Epigenomics
Smoke
Tobacco Products
Epithelial Cells