Hao Wang

Associate Professor

20012019
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Research Output 2001 2019

2019
Open Access
Mesenchymal Stromal Cells
Prostatic Neoplasms
Bone Marrow
Safety
Neoplasms

Correction to: persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1 (Journal for Immuno Therapy of Cancer (2019) 7 (40) DOI: 10.1186/s40425-018-0492-x)

Smith, K., Llosa, N., Cottrell, T. R., Siegel, N., Fan, H., Suri, P., Chan, H. Y., Guo, H., Oke, T., Awan, A. H., Verde, F., Danilova, L. V., Anagnostou, V., Tam, A. J., Luber, B. S., Bartlett, B. R., Aulakh, L. K., Sidhom, J. W., Zhu, Q., Sears, C. L. & 21 others, Cope, L., Sharfman, W., Thompson, E., Riemer, J., Marrone, K., Naidoo, J., Velculescu, V. E., Forde, P., Vogelstein, B., Kinzler, K. W., Papadopoulos, N., Durham, J. N., Wang, H., Le, D., Justesen, S., Taube, J. M., Diaz, L. A., Brahmer, J., Pardoll, A. M., Anders, R. A. & Housseau, F., Mar 6 2019, In : Journal for immunotherapy of cancer. 7, 1, 7.

Research output: Contribution to journalComment/debate

Consultants
Oncogenes
T-Lymphocytes
Conflict of Interest
Organized Financing

Genetic diversity of tumors with mismatch repair deficiency influences anti-PD-1 immunotherapy response

Mandal, R., Samstein, R. M., Lee, K. W., Havel, J. J., Wang, H., Krishna, C., Sabio, E. Y., Makarov, V., Kuo, F., Blecua, P., Ramaswamy, A. T., Durham, J. N., Bartlett, B., Ma, X., Srivastava, R., Middha, S., Zehir, A., Hechtman, J. F., Morris, L. G., Weinhold, N. & 4 others, Riaz, N., Le, D., Diaz, L. A. & Chan, T. A., May 3 2019, In : Science (New York, N.Y.). 364, 6439, p. 485-491 7 p.

Research output: Contribution to journalArticle

Immunotherapy
Cell Death
Microsatellite Instability
Neoplasms
Tumor Burden

Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic

Tomkovich, S., Dejea, C. M., Winglee, K., Drewes, J., Chung, L., Housseau, F., Pope, J. L., Gauthier, J., Sun, X., Mühlbauer, M., Liu, X., Fathi, P., Anders, R. A., Besharati, S., Perez-Chanona, E., Yang, Y., Ding, H., Wu, X., Wu, S., White, J. R. & 6 others, Gharaibeh, R. Z., Fodor, A. A., Wang, H., Pardoll, A. M., Jobin, C. & Sears, C. L., Apr 1 2019, In : Journal of Clinical Investigation. 129, 4, p. 1699-1712 14 p.

Research output: Contribution to journalArticle

Open Access
Biofilms
Colonic Neoplasms
Colon
Colonoscopy
Neoplasms
Open Access
Mesenchymal Stromal Cells
Pharmaceutical Preparations
Neoplasms

Methylation biomarker panel performance in esophacap cytology samples for diagnosing Barrett's esophagus: A prospective validation study

Wang, Z., Kambhampati, S., Cheng, Y., Ma, K., Simsek, C., Tieu, A. H., Abraham, J. M., Liu, X., Prasath, V., Duncan, M. D., Stark, A., Trick, A., Tsai, H. L., Wang, H., He, Y., Khashab, M., Ngamruengphong, S., Shin, E., Wang, T. H. & Meltzer, S., Apr 1 2019, In : Clinical Cancer Research. 25, 7, p. 2127-2135 9 p.

Research output: Contribution to journalArticle

Barrett Esophagus
Validation Studies
Methylation
Cell Biology
Biomarkers

Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1

Smith, K., Llosa, N., Cottrell, T. R., Siegel, N., Fan, H., Suri, P., Chan, H. Y., Guo, H., Oke, T., Awan, A. H., Verde, F., Danilova, L. V., Anagnostou, V., Tam, A. J., Luber, B. S., Bartlett, B. R., Aulakh, L. K., Sidhom, J. W., Zhu, Q., Sears, C. L. & 21 others, Cope, L., Sharfman, W., Thompson, E., Riemer, J., Marrone, K., Naidoo, J., Velculescu, V. E., Forde, P., Vogelstein, B., Kinzler, K. W., Papadopoulos, N., Durham, J. N., Wang, H., Le, D., Justesen, S., Taube, J. M., Diaz, L. A., Brahmer, J., Pardoll, A. M., Anders, R. A. & Housseau, F., Feb 11 2019, In : Journal for immunotherapy of cancer. 7, 1, 40.

Research output: Contribution to journalArticle

Open Access
Oncogenes
T-Lymphocytes
Biomarkers
DNA Mismatch Repair
Neoplasms

The prognostic impact of pathologic lymph nodes in HPV-positive oropharyngeal cancers

El Asmar, M., Tsai, H. L., Fakhry, C., Maroun, C. A., Mandal, R., Pardoll, A. M. & Wang, H., Feb 1 2019, In : Oral Oncology. 89, p. 23-29 7 p.

Research output: Contribution to journalArticle

Oropharyngeal Neoplasms
Lymph Nodes
Radiotherapy
Squamous Cell Carcinoma
Survival
Wnt Signaling Pathway
Castration
Prostatic Neoplasms
Mutation
Prostate-Specific Antigen
2018

Germline DNA-repair Gene Mutations and Outcomes in Men with Metastatic Castration-resistant Prostate Cancer Receiving First-line Abiraterone and Enzalutamide

Antonarakis, E., Lu, C., Luber, B., Liang, C., Wang, H., Chen, Y., Silberstein, J. L., Piana, D., Lai, Z., Chen, Y., Isaacs, W. B. & Luo, J., Jan 1 2018, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

Castration
DNA Repair
Prostatic Neoplasms
Mutation
Germ-Line Mutation

Ipilimumab plus nivolumab and DNA-repair defects in AR-V7-expressing metastatic prostate cancer

Boudadi, K., Suzman, D. L., Anagnostou, V., Fu, W., Luber, B., Wang, H., Niknafs, N., White, J. R., Silberstein, J. L., Sullivan, R., Dowling, D., Harb, R., Nirschl, T. R., Veeneman, B. A., Tomlins, S. A., Wang, Y., Jendrisak, A., Graf, R. P., Dittamore, R., Carducci, M. A. & 8 others, Eisenberger, M., Haffner, M. C., Meeker, A. K., Eshleman, J., Luo, J., Velculescu, V. E., Drake, C. G. & Antonarakis, E., Jun 19 2018, In : Oncotarget. 9, 47, p. 28561-28571 11 p.

Research output: Contribution to journalArticle

DNA Repair
Disease-Free Survival
Prostatic Neoplasms
Survival
Circulating Neoplastic Cells

Neoadjuvant PD-1 blockade in resectable lung cancer

Forde, P., Chaft, J. E., Smith, K., Anagnostou, V., Cottrell, T. R., Hellmann, M. D., Zahurak, M., Broderick, S., Yang, S. C., Jones, D. R., Battafarano, R. J., Velez, M. J., Rekhtman, N., Olah, Z., Verde, F., Naidoo, J., Marrone, K., Guo, H., Sidhom, J. W., Zhang, J. & 15 others, Caushi, J. X., Chan, H. Y., Scharpf, R. B., White, J., Gabrielson, E., Wang, H., Rosner, G., Rusch, V., Wolchok, J. D., Merghoub, T., Taube, J. M., Velculescu, V. E., Topalian, S., Brahmer, J. & Pardoll, A. M., May 24 2018, In : New England Journal of Medicine. 378, 21, p. 1976-1986 11 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Clone Cells
Neoplasms
Non-Small Cell Lung Carcinoma
T-Lymphocytes

Non-toxigenic Bacteroides fragilis (NTBF) administration reduces bacteria-driven chronic colitis and tumor development independent of polysaccharide A

Chan, J. L., Wu, S., Geis, A., Chan, G. V., Gomes, T. A. M., Beck, S., Wu, X., Fan, H., Tam, A. J., Chung, L., Ding, H., Wang, H., Pardoll, A. M., Housseau, F. & Sears, C. L., Jan 1 2018, (Accepted/In press) In : Mucosal Immunology.

Research output: Contribution to journalArticle

Bacteroides fragilis
Colitis
Polysaccharides
Bacteria
Interleukin-17

Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria

Dejea, C. M., Fathi, P., Craig, J. M., Boleij, A., Taddese, R., Geis, A., Wu, X., DeStefano Shields, C. E., Hechenbleikner, E. M., Huso, D. L., Anders, R. A., Giardiello, F. M., Wick, E. C., Wang, H., Wu, S., Pardoll, A. M., Housseau, F. & Sears, C. L., Feb 2 2018, In : Science. 359, 6375, p. 592-597 6 p.

Research output: Contribution to journalArticle

Adenomatous Polyposis Coli
Biofilms
Bacteroides fragilis
Bacteria
Colorectal Neoplasms
alpha-Macroglobulins
Peptide Hormones
Prostate-Specific Antigen
Macroglobulins
Prostatic Neoplasms
2017
Prostatic Neoplasms
Radiotherapy
Observation
Radiation
Androgens

Bipolar androgen therapy in men with metastatic castration-resistant prostate cancer after progression on enzalutamide: An open-label, phase 2, multicohort study

Teply, B. A., Wang, H., Luber, B., Sullivan, R., Rifkind, I., Bruns, A., Spitz, A., DeCarli, M., Sinibaldi, V., Pratz, C. F., Lu, C., Silberstein, J. L., Luo, J., Schweizer, M. T., Drake, C. G., Carducci, M. A., Paller, C., Antonarakis, E., Eisenberger, M. & Denmeade, S. R., Jan 1 2017, (Accepted/In press) In : The Lancet Oncology.

Research output: Contribution to journalArticle

Castration
Androgens
Prostatic Neoplasms
Therapeutics
MDV 3100
Circulating Neoplastic Cells
Castration
Androgen Receptors
Prostatic Neoplasms
Messenger RNA

Immuno-oncology trial endpoints: Capturing clinically meaningful activity

Anagnostou, V., Yarchoan, M., Hansen, A. R., Wang, H., Verde, F., Sharon, E., Collyar, D., Chow, L. Q. M. & Forde, P., Sep 1 2017, In : Clinical Cancer Research. 23, 17, p. 4959-4969 11 p.

Research output: Contribution to journalArticle

Clinical Trials
Biomarkers
Survival Rate
Drug Therapy
Therapeutics

Mesenchymal stem cell infiltration during neoplastic transformation of the human prostate

Brennen, W., Zhang, B., Kulac, I., Kisteman, L. N., Antony, L., Wang, H., Meeker, A. K., Demarzo, A. M., Garraway, I. P., Denmeade, S. R. & Isaacs, J. T., 2017, In : Oncotarget. 8, 29, p. 46710-46727 18 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Prostate
Prostatic Neoplasms
Chondrogenesis
Adipogenesis

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

Le, D., Uram, J., Smith, K., Wang, H., Bartlett, B. R., Aulakh, L. K., Lu, S., Kemberling, H., Wilt, C., Luber, B. S., Wong, F., Azad, N., Rucki, A. A., Laheru, D., Donehower, R. C., Zaheer, A., Fisher, G. A., Crocenzi, T. S., Lee, J. J., Greten, T. F. & 26 others, Duffy, A. G., Ciombor, K. K., Eyring, A. D., Lam, B. H., Joe, A., Kang, S. P., Holdhoff, M., Danilova, L. V., Cope, L., Meyer, C., Zhou, S., Goldberg, R. M., Armstrong, D. K., Bever, K., Nickles Fader, A. N., Taube, J. M., Housseau, F., Spetzler, D., Xiao, N., Pardoll, A. M., Papadopoulos, N., Kinzler, K. W., Eshleman, J., Vogelstein, B., Anders, R. A. & Diaz, L. A., Jul 28 2017, In : Science. 357, 6349, p. 409-413 5 p.

Research output: Contribution to journalArticle

Neoplasms
DNA Mismatch Repair
Disease-Free Survival
Turcot syndrome
Colorectal Neoplasms

Quantitation of cancer treatment response by 18F-FDG PET/CT: Multicenter assessment of measurement variability

Hyun, J., Jacene, H., Luber, B., Wang, H., Huynh, M. H., Leal, J. P. & Wahl, R. L., Sep 1 2017, In : Journal of Nuclear Medicine. 58, 9, p. 1429-1434 6 p.

Research output: Contribution to journalArticle

Fluorodeoxyglucose F18
Confidence Intervals
Neoplasms
Therapeutics
Observer Variation

SMAD4 loss is associated with cetuximab resistance and induction of MAPK/JNK activation in head and neck cancer cells

Ozawa, H., Ranaweera, R. S., Izumchenko, E., Makarev, E., Zhavoronkov, A., Fertig, E., Howard, J. D., Markovic, A., Bedi, A., Ravi, R., Perez, J., Le, Q. T., Kong, C. S., Jordan, R. C., Wang, H., Kang, H., Quon, H., Sidransky, D. & Chung, C. H., Sep 1 2017, In : Clinical Cancer Research. 23, 17, p. 5162-5175 14 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Gene Knockdown Techniques
Phenotype
Cell Line
Cetuximab
2016

A prodrug-doped cellular Trojan Horse for the potential treatment of prostate cancer

Levy, O., Brennen, W., Han, E., Rosen, D. M., Musabeyezu, J., Safaee, H., Ranganath, S., Ngai, J., Heinelt, M., Milton, Y., Wang, H., Bhagchandani, S. H., Joshi, N., Bhowmick, N., Denmeade, S. R., Isaacs, J. T. & Karp, J. M., Jun 1 2016, In : Biomaterials. 91, p. 140-150 11 p.

Research output: Contribution to journalArticle

Prodrugs
Stem cells
Mesenchymal Stromal Cells
Prostatic Neoplasms
Prostate-Specific Antigen

Association of PD-1/PD-L axis expression with cytolytic activity, mutational load, and prognosis in melanoma and other solid tumors

Danilova, L. V., Wang, H., Sunshine, J., Kaunitz, G. J., Cottrell, T. R., Xu, H., Esandrio, J., Anders, R. A., Cope, L., Pardoll, A. M., Drake, C. G. & Taube, J. M., Nov 29 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 48, p. E7769-E7777

Research output: Contribution to journalArticle

Melanoma
Programmed Cell Death 1 Ligand 2 Protein
Neoplasms
Ligands
Programmed Cell Death 1 Receptor

Bipolar Androgen Therapy for Men With Androgen Ablation Naïve Prostate Cancer: Results From the Phase II BATMAN Study

Schweizer, M. T., Wang, H., Luber, B., Nadal, R., Spitz, A., Rosen, D. M., Cao, H., Antonarakis, E., Eisenberger, M., Carducci, M. A., Paller, C. & Denmeade, S. R., Sep 15 2016, In : Prostate. 76, 13, p. 1218-1226 9 p.

Research output: Contribution to journalArticle

Androgens
Prostatic Neoplasms
Therapeutics
Quality of Life
Hormones

Cetuximab activity in dysplastic lesions of the upper aerodigestive tract

Khan, Z., Epstein, J. B., Marur, S., Gillespie, M. B., Feldman, L., Tsai, H. L., Zhang, Z., Wang, H., Sciubba, J., Ferris, R., Grandis, J. R., Gibson, M., Koch, W. M., Tufano, R. P., Westra, W., Tsottles, N., Ozawa, H., Chung, C. & Califano, J. A., Feb 1 2016, In : Oral Oncology. 53, p. 60-66 7 p.

Research output: Contribution to journalArticle

Observation
Therapeutics
Nonparametric Statistics
Phase II Clinical Trials
Cetuximab

Corrigendum to "Cetuximab activity in dysplastic lesions of the upper aerodigestive tract" [Oral Oncol. 53 (2016) 60-66]

Khan, Z., Epstein, J. B., Marur, S., Boyd Gillespie, M., Feldman, L., Tsai, H. L., Zhang, Z., Wang, H., Sciubba, J., Ferris, R. L., Grandis, J. R., Gibson, M., Koch, W. M., Tufano, R. P., Westra, W., Tsottles, N., Ozawa, H., Chung, C. H. & Califano, J. A., 2016, (Accepted/In press) In : Oral Oncology.

Research output: Contribution to journalArticle

Cetuximab

Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells

Sadtler, K., Estrellas, K., Allen, B. W., Wolf, M. T., Fan, H., Tam, A. J., Patel, C. H., Luber, B. S., Wang, H., Wagner, K. R., Powell, J. D., Housseau, F., Pardoll, D. M. & Elisseeff, J. H., Apr 15 2016, In : Science. 352, 6283, p. 366-370 5 p.

Research output: Contribution to journalArticle

Th2 Cells
Biocompatible Materials
Regeneration
Muscles
Interleukin-4

Pharmacodynamic study of the oral hedgehog pathway inhibitor, vismodegib, in patients with metastatic castration-resistant prostate cancer

Maughan, B. L., Suzman, D. L., Luber, B., Wang, H., Glavaris, S., Hughes, R., Sullivan, R., Harb, R., Boudadi, K., Paller, C., Eisenberger, M., Demarzo, A. M., Ross, A. & Antonarakis, E., Dec 1 2016, In : Cancer Chemotherapy and Pharmacology. 78, 6, p. 1297-1304 8 p.

Research output: Contribution to journalArticle

HhAntag691
Pharmacodynamics
Castration
Prostatic Neoplasms
Biopsy

Posttreatment FDG PET/CT in predicting survival of patients with ovarian carcinoma

Chu, L. C. H., Tsai, H. L., Wang, H., Crandall, J., Javadi, M. S. S. & Wahl, R. L., May 20 2016, In : EJNMMI Research. 6, 1, 42.

Research output: Contribution to journalArticle

Carcinoma
Survival
Multivariate Analysis
Research Ethics Committees
Serum

Quantifying over-estimation in early stopped clinical trials and the "freezing effect" on subsequent research

Wang, H., Rosner, G. & Goodman, S. N., Dec 1 2016, In : Clinical Trials. 13, 6, p. 621-631 11 p.

Research output: Contribution to journalArticle

Freezing
Randomized Controlled Trials
Clinical Trials
Research
Hospital Distribution Systems

Reduction of Murine Colon Tumorigenesis Driven by Enterotoxigenic Bacteroides fragilis Using Cefoxitin Treatment

Destefano Shields, C. E., Van Meerbeke, S. W., Housseau, F., Wang, H., Huso, D. L., Casero, R. A., O'Hagan, H. M. & Sears, C. L., Jul 1 2016, In : Journal of Infectious Diseases. 214, 1, p. 122-129 8 p.

Research output: Contribution to journalArticle

Cefoxitin
Bacteroides fragilis
Colon
Carcinogenesis
Interleukin-17

Response to early treatment evaluated with 18F-FDG PET and PERCIST 1.0 predicts survival in patients with ewing sarcoma family of tumors treated with a monoclonal antibody to the insulinlike growth factor 1 receptor

Joo, H. O., Luber, B. S., Leal, J. P., Wang, H., Bolejack, V., Schuetze, S. M., Schwartz, L. H., Helman, L. J., Reinke, D., Baker, L. H. & Wahl, R. L., May 1 2016, In : Journal of Nuclear Medicine. 57, 5, p. 735-740 6 p.

Research output: Contribution to journalArticle

Ewing's Sarcoma
Growth Factor Receptors
Fluorodeoxyglucose F18
Monoclonal Antibodies
Survival

Serum biomarkers for detection of head and neck squamous cell carcinoma

Mydlarz, W., Hennessey, P. T., Wang, H., Carvalho, A. L. & Califano, J. A., Jan 1 2016, In : Head and Neck. 38, 1, p. 9-14 6 p.

Research output: Contribution to journalArticle

Endothelin B Receptors
Biomarkers
Cyclin-Dependent Kinase Inhibitor p16
Serum
Methylation
2015
Castration
Androgen Receptors
Prostatic Neoplasms
Drug Therapy
Prostate-Specific Antigen

Comparing staging by positron emission tomography with contrast-enhanced computed tomography and by pathology in head and neck squamous cell carcinoma

Qualliotine, J. R., Mydlarz, W., Chan, J. Y., Zhou, X., Wang, H. & Agrawal, N., May 25 2015, In : Journal of Laryngology and Otology. 129, 12, p. 1213-1219 7 p.

Research output: Contribution to journalArticle

Positron-Emission Tomography
Tomography
Pathology
Neoplasms
Multivariate Analysis
Castration
Androgens
Prostatic Neoplasms
Testosterone
Androgen Receptors

Factors affecting the repeatability of gamma camera calibration for quantitative imaging applications using a sealed source

Anizan, N., Wang, H., Zhou, X. C., Wahl, R. L. & Frey, E., Feb 7 2015, In : Physics in Medicine and Biology. 60, 3, p. 1325-1337 13 p.

Research output: Contribution to journalArticle

Gamma Cameras
Calibration
Noise
Nuclear Medicine
Single-Photon Emission-Computed Tomography

Optimal definition of biological tumor volume using positron emission tomography in an animal model

Wu, I., Wang, H., Huso, D. & Wahl, R. L., Dec 1 2015, In : EJNMMI Research. 5, 1, 58.

Research output: Contribution to journalArticle

Tumor Burden
Positron-Emission Tomography
Animal Models
Neoplasms
Histology

Outlier analysis defines zinc finger gene family DNA methylation in tumors and saliva of head and neck cancer patients

Gaykalova, D., Vatapalli, R., Wei, Y., Tsai, H. L., Wang, H., Zhang, C., Hennessey, P. T., Guo, T., Tan, M., Li, R., Ahn, J., Khan, Z., Westra, W. H., Bishop, J. A., Zaboli, D., Koch, W. M., Khan, T., Ochs, M. F. & Califano, J. A., Nov 6 2015, In : PLoS One. 10, 11, e0142148.

Research output: Contribution to journalArticle

zinc finger motif
Zinc Fingers
squamous cell carcinoma
DNA methylation
DNA Methylation

PD-1 blockade in tumors with mismatch-repair deficiency

Le, D., Uram, J., Wang, H., Bartlett, B. R., Kemberling, H., Eyring, A. D., Skora, A. D., Luber, B. S., Azad, N., Laheru, D., Biedrzycki, B., Donehower, R. C., Zaheer, A., Fisher, G. A., Crocenzi, T. S., Lee, J. J., Duffy, S. M., Goldberg, R. M., De La Chapelle, A., Koshiji, M. & 15 others, Bhaijee, F., Huebner, T., Hruban, R. H., Wood, L. D., Cuka, N., Pardoll, A. M., Papadopoulos, N., Kinzler, K. W., Zhou, S., Cornish, T. C., Taube, J. M., Anders, R. A., Eshleman, J., Vogelstein, B. & Diaz, L. A., Jun 25 2015, In : New England Journal of Medicine. 372, 26, p. 2509-2520 12 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Colorectal Neoplasms
Neoplasms
Disease-Free Survival
Survival Rate

PD-L1 expression in melanocytic lesions does not correlate with the BRAF V600E mutation

Rodic, N., Anders, R. A., Eshleman, J., Lin, M-T., Xu, H., Kim, J. H., Beierl, K., Chen, S., Luber, B. S., Wang, H., LTopalian, S., Pardoll, A. M. & Taube, J. M., Feb 1 2015, In : Cancer immunology research. 3, 2, p. 110-115 6 p.

Research output: Contribution to journalArticle

Tumor-Infiltrating Lymphocytes
Melanoma
Mutation
Melanocytes
Cell Line

Repeatability of radiotracer uptake in normal abdominal organs with 111In-pentetreotide quantitative SPECT/CT

Rowe, S., Vicente, E., Anizan, N., Wang, H., Leal, J. P., Lodge, M., Frey, E. & Wahl, R. L., Jul 1 2015, In : Journal of Nuclear Medicine. 56, 7, p. 985-988 4 p.

Research output: Contribution to journalArticle

Single-Photon Emission-Computed Tomography
Kidney
Liver
Fluorodeoxyglucose F18
Single Photon Emission Computed Tomography Computed Tomography

Safety and immunologic correlates of Melanoma GVAX, a GM-CSF secreting allogeneic melanoma cell vaccine administered in the adjuvant setting

Lipson, E., Sharfman, W., Chen, S., McMiller, T. L., Pritchard, T. S., Salas, J. T., Sartorius-Mergenthaler, S., Freed, I., Ravi, S., Wang, H., Luber, B., Davis Sproul, J., Taube, J. M., Pardoll, A. M. & Topalian, S., Jul 5 2015, In : Journal of Translational Medicine. 13, 1, 214.

Research output: Contribution to journalArticle

Granulocyte-Macrophage Colony-Stimulating Factor
Melanoma
Vaccines
Safety
Biopsy

Tadalafil augments tumor specific immunity in patients with head and neck squamous cell carcinoma

Califano, J. A., Khan, Z., Noonan, K., Rudraraju, L., Zhang, Z., Wang, H., Goodman, S., Gourin, C., Ha, P. K., Fakhry, C., Saunders, J., Levine, M., Tang, M., Neuner, G., Richmon, J. D., Blanco, R. G. F., Agrawal, N., Koch, W. M., Marur, S., Weed, D. T. & 2 others, Serafini, P. & Borrello, I. M., Jan 1 2015, In : Clinical Cancer Research. 21, 1, p. 30-38 9 p.

Research output: Contribution to journalArticle

Immunity
Head and Neck Neoplasms
Neoplasms
Phosphodiesterase 5 Inhibitors
Type 5 Cyclic Nucleotide Phosphodiesterases

The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints

Llosa, N., Cruise, M., Tam, A., Wicks, E. C., Hechenbleikner, E. M., Taube, J. M., Blosser, R. L., Fan, H., Wang, H., Luber, B. S., Zhang, M., Papadopoulos, N., Kinzler, K. W., Vogelstein, B., Sears, C. L., Anders, R. A., Pardoll, A. M. & Housseau, F., 2015, In : Cancer Discovery. 5, 1, p. 43-51 9 p.

Research output: Contribution to journalArticle

Microsatellite Repeats
Colonic Neoplasms
Microsatellite Instability
Cytotoxic T-Lymphocytes
Colorectal Neoplasms

Tumor-specific expression and detection of a CEST reporter gene

Minn, I., Bar-Shir, A., Yarlagadda, K., Bulte, J. W., Fisher, P. B., Wang, H., Gilad, A. A. & Pomper, M. G., Aug 1 2015, In : Magnetic Resonance in Medicine. 74, 2, p. 544-549 6 p.

Research output: Contribution to journalArticle

Reporter Genes
Lysine
Neoplasms
Proteins
Molecular Imaging