Han-Sol Park

Research output

Research output per year 2011 2021 2022 2023 2023

• 21 Article
• 1 Review article

Research output per year

Research output per year

Search results

• 2023

  Spike-protein proteolytic antibodies in COVID-19 convalescent plasma contribute to SARS-CoV-2 neutralization

  McConnell, S. A., Sachithanandham, J., Mudrak, N. J., Zhu, X., Farhang, P. A., Cordero, R. J. B., Wear, M. P., Shapiro, J. R., Park, H. S., Klein, S. L., Tobian, A. A. R., Bloch, E. M., Sullivan, D. J., Pekosz, A. & Casadevall, A., Jul 20 2023, In: Cell Chemical Biology. 30, 7, p. 726-738.e4

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Neutralization 68%
  • Protein Hydrolysis 48%
  • Plasma 41%
  • Antibodies 37%

• The intersection of biological sex and gender in adverse events following seasonal influenza vaccination in older adults

  Shapiro, J. R., Seddu, K., Park, H. S., Lee, J. S., Creisher, P. S., Yin, A., Shea, P., Kuo, H., Li, H., Abrams, E., Leng, S. X., Morgan, R. & Klein, S. L., Dec 2023, In: Immunity and Ageing. 20, 1, 43.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Human Influenza 100%
  • Vaccination 86%
  • Influenza Vaccines 22%
  • Sex Characteristics 18%
  • Estradiol 17%

• Transfusing Convalescent Plasma as Post-Exposure Prophylaxis Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Double-Blinded, Phase 2 Randomized, Controlled Trial

  Shoham, S., Bloch, E. M., Casadevall, A., Hanley, D., Lau, B., Gebo, K., Cachay, E., Kassaye, S. G., Paxton, J. H., Gerber, J., Levine, A. C., Naeim, A., Currier, J., Patel, B., Allen, E. S., Anjan, S., Appel, L., Baksh, S., Blair, P. W., Bowen, A., & 36 othersBroderick, P., Caputo, C. A., Cluzet, V., Cordisco, M. E., Cruser, D., Ehrhardt, S., Forthal, D., Fukuta, Y., Gawad, A. L., Gniadek, T., Hammel, J., Huaman, M. A., Jabs, D. A., Jedlicka, A., Karlen, N., Klein, S., Laeyendecker, O., Lane, K., McBee, N., Meisenberg, B., Merlo, C., Mosnaim, G., Park, H. S., Pekosz, A., Petrini, J., Rausch, W., Shade, D. M., Shapiro, J. R., Robinson Singleton, J., Sutcliffe, C., Thomas, D. L., Yarava, A., Zand, M., Zenilman, J. M., Tobian, A. A. R. & Sullivan, D. J., Feb 1 2023, In: Clinical Infectious Diseases. 76, 3, p. E477-E486

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Post-Exposure Prophylaxis 100%
  • Severe Acute Respiratory Syndrome 88%
  • Coronavirus 60%
  • Randomized Controlled Trials 46%
  • Infections 13%
• 2022

  Adaptive immune responses in vaccinated patients with symptomatic SARS-CoV-2 Alpha infection

  Park, H. S., Shapiro, J. R., Sitaras, I., Woldemeskel, B. A., Garliss, C. C., Dziedzic, A., Sachithanandham, J., Jedlicka, A. E., Caputo, C. A., Rousseau, K. E., Thakar, M., Suwanmanee, S., Hauk, P., Aliyu, L., Majewska, N. I., Koley, S., Patel, B., Broderick, P., Mosnaim, G., Heath, S. L., & 18 othersSpivak, E. S., Shenoy, A., Bloch, E. M., Gniadek, T. J., Shoham, S., Casadevall, A., Hanley, D., Cox, A. L., Laeyendecker, O., Betenbaugh, M. J., Cramer, S. M., Mostafa, H. H., Pekosz, A., Blankson, J. N., Klein, S. L., Tobian, A. A. R., Sullivan, D. & Gebo, K. A., Mar 8 2022, In: JCI Insight. 7, 5, e155944.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Adaptive Immunity 69%
  • Neutralizing Antibodies 50%
  • Viruses 45%
  • Vaccination 40%

• Association of Frailty, Age, and Biological Sex with Severe Acute Respiratory Syndrome Coronavirus 2 Messenger RNA Vaccine–Induced Immunity in Older Adults

  Shapiro, J. R., Sitaras, I., Park, H. S., Aytenfisu, T. Y., Caputo, C., Li, M., Lee, J., Johnston, T. S., Li, H., Wouters, C., Hauk, P., Jacobsen, H., Li, Y., Abrams, E., Yoon, S., Kocot, A. J., Yang, T., Huang, Y., Cramer, S. M., Betenbaugh, M. J., & 7 othersDebes, A. K., Morgan, R., Milstone, A. M., Karaba, A. H., Pekosz, A., Leng, S. X. & Klein, S. L., Aug 15 2022, In: Clinical Infectious Diseases. 75, 1, p. S61-S71

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Frailty 88%
  • Immunity 63%
  • Messenger RNA 44%

• Greater Breadth of Vaccine-Induced Immunity in Females than Males Is Mediated by Increased Antibody Diversity in Germinal Center B Cells

  Ursin, R. L., Dhakal, S., Liu, H., Jayaraman, S., Park, H. S., Powell, H. R., Sherer, M. L., Littlefield, K. E., Fink, A. L., Ma, Z., Mueller, A. L., Chen, A. P., Seddu, K., Woldetsadik, Y. A., Gearhart, P. J., Larman, H. B., Maul, R. W., Pekosz, A. & Klein, S. L., Aug 2022, In: mBio. 13, 4

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Antibody Diversity 100%
  • Germinal Center 71%
  • Immunity 49%
  • B-Lymphocytes 46%
  • Vaccines 45%

• Sex-specific effects of age and body mass index on antibody responses to seasonal influenza vaccines in healthcare workers

  Kuo, H., Shapiro, J. R., Dhakal, S., Morgan, R., Fink, A. L., Liu, H., Westerbeck, J. W., Sylvia, K. E., Park, H. S., Ursin, R. L., Shea, P., Shaw-Saliba, K., Fenstermacher, K., Rothman, R., Pekosz, A. & Klein, S. L., Mar 8 2022, In: Vaccine. 40, 11, p. 1634-1642 9 p.

  Research output: Contribution to journal › Article › peer-review

  • influenza vaccines 100%
  • health care workers 85%
  • body mass index 82%
  • Influenza Vaccines 76%
  • vaccination 75%

• The immune phenotype of perinatal anxiety

  Sherer, M. L., Voegtline, K. M., Park, H. S., Miller, K. N., Shuffrey, L. C., Klein, S. L. & Osborne, L. M., Nov 2022, In: Brain, Behavior, and Immunity. 106, p. 280-288 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Anxiety 100%
  • Phenotype 83%
  • Postpartum Period 37%
  • Pregnancy 30%
  • Cytokines 24%
• 2021

  Auto-Antibody Production During Experimental Atherosclerosis in ApoE^-/- Mice

  Hutchinson, M. A., Park, H. S., Zanotti, K. J., Alvarez-Gonzalez, J., Zhang, J., Zhang, L., Telljohann, R., Wang, M., Lakatta, E. G., Gearhart, P. J. & Maul, R. W., Jul 9 2021, In: Frontiers in immunology. 12, 695220.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apolipoproteins E 100%
  • Antibody Formation 84%
  • Atherosclerosis 76%
  • Immunoglobulin M 52%
  • Antibodies 52%

• Delayed Rise of Oral Fluid Antibodies, Elevated BMI, and Absence of Early Fever Correlate with Longer Time to SARS-CoV-2 RNA Clearance in a Longitudinally Sampled Cohort of COVID-19 Outpatients

  Antar, A. A. R., Yu, T., Pisanic, N., Azamfirei, R., Tornheim, J. A., Brown, D. M., Kruczynski, K., Hardick, J. P., Sewell, T., Jang, M., Church, T., Walch, S. N., Reuland, C., Bachu, V. S., Littlefield, K., Park, H. S., Ursin, R. L., Ganesan, A., Kusemiju, O., Barnaba, B., & 24 othersCharles, C., Prizzi, M., Johnstone, J. R., Payton, C., Dai, W., Fuchs, J., Massaccesi, G., Armstrong, D. T., Townsend, J. L., Keller, S. C., Demko, Z. O., Hu, C., Wang, M. C., Sauer, L. M., Mostafa, H. H., Keruly, J. C., Mehta, S. H., Klein, S. L., Cox, A. L., Pekosz, A., Heaney, C. D., Thomas, D. L., Blair, P. W. & Manabe, Y. C., Jun 1 2021, In: Open Forum Infectious Diseases. 8, 6, ofab195.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Outpatients 58%
  • Fever 58%
  • Body Mass Index 55%

• Durable SARS-CoV-2 B cell immunity after mild or severe disease

  Ogega, C. O., Skinner, N. E., Blair, P. W., Park, H. S., Littlefield, K., Ganesan, A., Dhakal, S., Ladiwala, P., Antar, A. A. R., Ray, S. C., Betenbaugh, M. J., Pekosz, A., Klein, S. L., Manabe, Y. C., Cox, A. L. & Bailey, J. R., Apr 1 2021, In: Journal of Clinical Investigation. 131, 7, e145516.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Immunity 55%
  • B-Lymphocytes 52%
  • Protein Binding 48%
  • Coronavirus 36%
  3 Scopus citations

• Pregnancy alters interleukin-1 beta expression and antiviral antibody responses during severe acute respiratory syndrome coronavirus 2 infection

  Sherer, M. L., Lei, J., Creisher, P. S., Jang, M., Reddy, R., Voegtline, K., Olson, S., Littlefield, K., Park, H. S., Ursin, R. L., Ganesan, A., Boyer, T., Elsayed, N., Brown, D. M., Walch, S. N., Antar, A. A. R., Manabe, Y. C., Jones-Beatty, K., Golden, W. C., Satin, A. J., & 4 othersSheffield, J. S., Pekosz, A., Klein, S. L. & Burd, I., Sep 2021, In: American journal of obstetrics and gynecology. 225, 3, p. 301.e1-301.e14

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome 90%
  • Coronavirus 67%
  • Interleukin-1beta 66%
  • Antibody Formation 62%
  • Antiviral Agents 59%

• Self-Collected Oral Fluid Saliva Is Insensitive Compared with Nasal-Oropharyngeal Swabs in the Detection of Severe Acute Respiratory Syndrome Coronavirus 2 in Outpatients

  Ambulatory COVID Team, Feb 1 2021, In: Open Forum Infectious Diseases. 8, 2, ofaa648.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Nose 62%
  • Outpatients 58%
  • Gingival Crevicular Fluid 21%

• The Clinical Course of COVID-19 in the Outpatient Setting: A Prospective Cohort Study

  Ambulatory COVID Study Team, Feb 1 2021, In: Open Forum Infectious Diseases. 8, 2, ofab007.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Coronavirus 100%
  • Outpatients 59%
  • Hospitalization 58%
  • Cohort Studies 54%
  • Prospective Studies 50%
  3 Scopus citations
• 2020

  Androgen receptor signaling in the lungs mitigates inflammation and improves the outcome of influenza in mice

  Vom Steeg, L. G., Dhakal, S., Woldetsadik, Y. A., Park, H. S., Mulka, K. R., Reilly, E. C., Topham, D. J. & Klein, S. L., Jul 2020, In: PLoS pathogens. 16, 7, e1008506.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • androgen receptors 100%
  • influenza 90%
  • Influenza A virus 85%
  • Androgen Receptors 83%
  • Human Influenza 71%
  3 Scopus citations

• Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population

  Klein, S. L., Pekosz, A., Park, H. S., Ursin, R. L., Shapiro, J. R., Benner, S. E., Littlefield, K., Kumar, S., Naik, H. M., Betenbaugh, M. J., Shrestha, R., Wu, A. A., Hughes, R. M., Burgess, I., Caturegli, P., Laeyendecker, O., Quinn, T. C., Sullivan, D., Shoham, S., Redd, A. D., & 3 othersBloch, E. M., Casadevall, A. & Tobian, A. A. R., Nov 2 2020, In: Journal of Clinical Investigation. 130, 11, p. 6141-6150 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Coronavirus 100%
  • Antibody Formation 71%
  • Immunoglobulin G 60%
  • Hospitalization 58%
  • Neutralizing Antibodies 53%
  62 Scopus citations
• 2019

  B cells from young and old mice switch isotypes with equal frequencies after ex vivo stimulation

  Russell Knode, L. M., Park, H. S., Maul, R. W. & Gearhart, P. J., Nov 2019, In: Cellular Immunology. 345, 103966.

  Research output: Contribution to journal › Article › peer-review

  • B-Lymphocytes 100%
  • AICDA (activation-induced cytidine deaminase) 38%
  • B-Cell Antigen Receptors 33%
  • B-Lymphocyte Subsets 32%
  • Inbred C57BL Mouse 24%
  5 Scopus citations

• Generation of sRAGE^high transgenic mice to study inflammaging

  Peng, Y., Park, H. S., Tang, L. A., Horwitz, N. & Lin, L., Jan 1 2019, In: Frontiers in Bioscience - Landmark. 24, 3, p. 555-563 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Advanced Glycation End-Product 100%
  • Receptor for Advanced Glycation End Products 91%
  • Transgenic Mice 63%
  • Pathogen-Associated Molecular Pattern Molecules 56%
  • Ligands 39%
  5 Scopus citations
• 2017

  Protective role of endogenous plasmalogens against hepatic steatosis and steatohepatitis in mice

  Jang, J. E., Park, H. S., Yoo, H. J., Baek, I. J., Yoon, J. E., Ko, M. S., Kim, A. R., Kim, H. S., Park, H. S., Lee, S. E., Kim, S. W., Kim, S. J., Leem, J., Kang, Y. M., Jung, M. K., Pack, C. G., Kim, C. J., Sung, C. O., Lee, I. K., Park, J. Y., & 3 othersFernández-Checa, J. C., Koh, E. H. & Lee, K. U., Aug 2017, In: Hepatology. 66, 2, p. 416-431 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Plasmalogens 100%
  • Fatty Liver 68%
  • Non-alcoholic Fatty Liver Disease 46%
  • Peroxisome Proliferator-Activated Receptors 38%
  • Liver 33%
  33 Scopus citations
• 2016

  AGE-RAGE signal generates a specific NF-Κ B RelA "barcode" that directs collagen i expression

  Peng, Y., Kim, J. M., Park, H. S., Yang, A., Islam, C., Lakatta, E. G. & Lin, L., Jan 5 2016, In: Scientific reports. 6, 18822.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Collagen 100%
  • NF-kappa B 93%
  • Advanced Glycation End Products 52%
  • Post Translational Protein Processing 45%
  • Sugars 42%
  19 Scopus citations

• Statins increase mitochondrial and peroxisomal fatty acid oxidation in the liver and prevent non-alcoholic steatohepatitis in mice

  Park, H. S., Jang, J. E., Ko, M. S., Woo, S. H., Kim, B. J., Kim, H. S., Park, H. S., Park, I. S., Koh, E. H. & Lee, K. U., 2016, In: Diabetes and Metabolism Journal. 40, 5, p. 376-385 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Fatty Liver 100%
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors 91%
  • Fatty Acids 79%
  • Choline 50%
  • Methionine 48%
  34 Scopus citations
• 2011

  Time-dependent changes in lipid metabolism in mice with methionine choline deficiency-induced fatty liver disease

  Park, H. S., Jeon, B. H., Woo, S. H., Leem, J., Jang, J. E., Cho, M. S., Park, I. S., Lee, K. U. & Koh, E. H., Dec 2011, In: Molecules and cells. 32, 6, p. 571-577 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Choline Deficiency 100%
  • Choline 63%
  • Fatty Liver 63%
  • Methionine 61%
  • Lipid Metabolism 57%
  13 Scopus citations