Haig Kazazian

Professor

1965 …2020

Research output per year

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Research Output

1988

Restriction endonuclease mapping of six novel deletions of the factor VIII gene in hemophilia A

Youssoufian, H., Kasper, C. K., Phillips, D. G., Kazazian, H. H. & Antonarakis, S. E., Oct 1 1988, In : Human genetics. 80, 2, p. 143-148 6 p.

Research output: Contribution to journalArticle

The molecular basis of hemophilia A in man

Antonarakis, S. E. & Kazazian, H. H., Aug 1988, In : Trends in Genetics. 4, 8, p. 233-237 5 p.

Research output: Contribution to journalReview article

The spectrum of β-thalassaemia mutations in Sicily

Di Marzo, R., Dowling, C. E., Wong, C., Maggio, A. & Kazazian, H. H., 1988, In : British journal of haematology. 69, 3, p. 393-397 5 p.

Research output: Contribution to journalArticle

The varieties of mutation.

Kazazian, H. H. & Antonarakis, S. E., Jan 1 1988, In : Progress in medical genetics. 7, p. 43-67 25 p.

Research output: Contribution to journalReview article

βthalassemia in China: A systematic molecular characterization of βthalassemia mutations

Huang, S., Waber, P. G., Dowling, C. E., Wong, C., Antonarakis, S. E., Cai, R. L., Wang, M. Q., Lo, W. H. Y. & Kazazian, H. H., Jan 1 1988, In : Hemoglobin. 12, 5-6, p. 621-628 8 p.

Research output: Contribution to journalArticle

1987

A new mutation of IVS-1 of the human β globin gene causing β thalassemia due to abnormal splicing

Atweh, G. F., Wong, C., Reed, R., Antonarakis, S. E., Zhu, D., Ghosh, P. K., Maniatis, T., Forget, B. G. & Kazazian, H. H., Sep 23 1987, In : Blood. 70, 1, p. 147-151 5 p.

Research output: Contribution to journalArticle

Characterization of five partial deletions of the factor VIII gene

Youssoufian, H., Antonarakis, S. E., Aronis, S., Tsiftis, G., Phillips, D. G. & Kazazian, H. H., Aug 14 1987, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 11, p. 3772-3776 5 p.

Research output: Contribution to journalArticle

Characterization of β-thalassaemia mutations using direct genomic sequencing of amplified single copy DNA

Wong, C., Dowling, C. E., Saiki, R. K., Higuchi, R. G., Erlich, H. A. & Kazazian, H. H., Jan 1 1987, In : Nature. 330, 6146, p. 384-386 3 p.

Research output: Contribution to journalArticle

Globin gene structure and the nature of mutation.

Kazazian, H. H., 1987, In : Birth defects original article series. 23, 3, p. 77-92 16 p.

Research output: Contribution to journalReview article

Linkage analysis of neurofibromatosis

Kittur, S., Lubs, M. L., Bauer, M., Chakravarti, A. & Kazazian, H., Jan 1 1987, In : Journal of medical genetics. 24, 9, p. 526-527 2 p.

Research output: Contribution to journalArticle

Molecular characterization of beta-thalassemia major and beta-thalassemia intermedia in China and Southeast Asia.

Kazazian, H. H., Dowling, C. E., Waber, P. G., Huang, S. Z., Lo, W. H., Li, A., Tam, J. W., Kang, J. & Antonarakis, S. E., 1987, In : Progress in clinical and biological research. 251, p. 401-412 12 p.

Research output: Contribution to journalArticle

Molecular genetics of hemophilia A in man (factor VIII deficiency).

Antonarakis, S. E., Youssoufian, H. & Kazazian, H. H., Apr 1 1987, In : Molecular biology & medicine. 4, 2, p. 81-94 14 p.

Research output: Contribution to journalReview article

Mspl polymorphism in the 3′ flanking region of the human factor VIII gene

Youssoufian, H., Phillips, D. G., Kazazian, H. H. & Antonarakis, S. E., Aug 11 1987, In : Nucleic acids research. 15, 15, 1 p.

Research output: Contribution to journalArticle

Multipoint mapping studies of six loci on chromosome 11

Meyers, D. A., Beaty, T. H., Maestri, N. E., Kittur, S. D., Antonarakis, S. E. & Kazazian, H. H., Jan 1 1987, In : Human Heredity. 37, 2, p. 94-101 8 p.

Research output: Contribution to journalArticle

Report of the committee on the genetic constitution of chromosomes 10, 11 and 12

Kazazian, H. H. & Junien, C., Dec 1 1987, In : Cytogenetics and Cell Genetics. 46, 1-4, p. 188-212 25 p.

Research output: Contribution to journalArticle

The β-globin gene on the Chinese δβ-thalassemia chromosome carries a promoter mutation

Atweh, G. F., Zhu, X. X., Brickner, H. E., Dowling, C. H., Kazazian, H. H. & Forget, B. G., 1987, In : Blood. 70, 5, p. 1470-1474 5 p.

Research output: Contribution to journalArticle

Open Access
1986

Characterization of a spontaneous mutation to a β-thalassemia allele

Kazazian, H. H., Orkin, S. H., Boehm, C. D., Goff, S. C., Wong, C., Dowling, C. E., Newburger, P. E., Knowlton, R. G., Brown, V. & Donis-Keller, H., Nov 12 1986, In : American journal of human genetics. 38, 6, p. 860-867 8 p.

Research output: Contribution to journalArticle

Chinese (A)γ fetal hemoglobin: C to T substitution at position - 196 of the (A)γ gene promoter

Gelinas, R., Bender, M., Lotshaw, C., Waber, P., Kazazian, H. & Stamatoyannopoulos, G., 1986, In : Blood. 67, 6, p. 1777-1779 3 p.

Research output: Contribution to journalArticle

Open Access

Comparison of deficiency alleles of the β-globin and factor VIII:C genes: New lessons from a giant gene

Kazazian, H. H., Antonarakis, S. E., Youssoufian, H., Dowling, C. E., Phillips, D. G., Wong, C. & Boehm, C. D., Dec 1 1986, In : Cold Spring Harbor symposia on quantitative biology. 51, 1, p. 371-379 9 p.

Research output: Contribution to journalArticle

Concordance of a point mutation 5' to the (A)γ-globin gene with (A)γβ+ hereditary persistence of fetal hemoglobin in Greeks

Waber, P. G., Bender, M. A., Gelinas, R. E., Kattamis, C., Karaklis, A., Sofroniadou, K., Stamatoyannopoulos, G., Collins, F. S., Forget, B. G. & Kazazian, H. H., 1986, In : Blood. 67, 2, p. 551-554 4 p.

Research output: Contribution to journalArticle

Open Access

DNA analysis in genetic disorders.

Francomano, C. A. & Kazazian, H. H., 1986, In : Annual review of medicine. 37, p. 377-395 19 p.

Research output: Contribution to journalReview article

DNA polymorphic sites in the human apoAI-Ciii-AIV cluster: Taq I and ava I

Cohen, T., Karathanasis, S. K., Kazazian, H. H. & Antonarakis, S. E., Feb 25 1986, In : Nucleic acids research. 14, 4, p. 1924 1 p.

Research output: Contribution to journalArticle

Genetic analysis workshop IV: The 11p data sets

Meyers, D. A., Beaty, T. L., Antonarakis, S. E., Kazazian, H. & White, R., 1986, In : Genetic Epidemiology. 3, 1 S, p. 93-97 5 p.

Research output: Contribution to journalArticle

Multipoint mapping studies of the beta-globin, insulin, and c-Ha-ras-1 loci on 11p.

Meyers, D. A., Beaty, T. H., Maestri, N. E., Antonarakis, S. E. & Kazazian, H. H., Oct 1 1986, In : American journal of human genetics. 39, 4, p. 539-541 3 p.

Research output: Contribution to journalArticle

Recurrent mutations in haemophilia a give evidence for CpG mutation hotspots

Youssoufian, H., Kazazian, H. H., Phillips, D. G., Aronis, S., Tsiftis, G., Brown, V. A. & Antonarakis, S. E., Dec 1 1986, In : Nature. 324, 6095, p. 380-382 3 p.

Research output: Contribution to journalArticle

The same "TATA" box β-thalassemia mutation in Chinese and US blacks: another example of independent origins of mutation

Huang, S., Wong, C., Antonarakis, S. E., Ro-lien, T., Lo, W. H. Y. & Kazazian, H. H., Oct 1 1986, In : Human genetics. 74, 2, p. 162-164 3 p.

Research output: Contribution to journalArticle

The spectrum of β-thalassemia genes in China and southeast Asia

Kazazian, H. H., Dowling, C. E., Waber, P. G., Huang, S. & Lo, W. H., Dec 1 1986, In : Blood. 68, 4, p. 964-966 3 p.

Research output: Contribution to journalArticle

The William Allan Memorial Award presented to Yuet Wai Kan.

Kazazian, H. H., Jan 1 1986, In : American journal of human genetics. 38, 1, p. 1-3 3 p.

Research output: Contribution to journalArticle

Use of oligonucleotide hybridization in the characterization of a β(o)-thalassemia gene (β37 TGG→TGA) in a Saudi Arabian family

Boehm, C. D., Dowling, C. E., Waber, P. G., Giardina, P. J. & Kazazian, H. H., 1986, In : Blood. 67, 4, p. 1185-1188 4 p.

Research output: Contribution to journalArticle

Open Access
1985

A linkage map of three anonymous human DNA fragments and SOD-1 on chromosome 21.

Kittur, S. D., Antonarakis, S. E., Tanzi, R. E., Meyers, D. A., Chakravarti, A., Groner, Y., Phillips, J. A., Watkins, P. C., Gusella, J. F. & Kazazian, H. H., Sep 1985, In : The EMBO journal. 4, 9, p. 2257-2260 4 p.

Research output: Contribution to journalArticle

DNA polymorphism and molecular pathology of the human globin gene clusters

Antonarakis, S. E., Kazazian, H. H. & Orkin, S. H., May 1 1985, In : Human genetics. 70, 1, p. 95-99 5 p.

Research output: Contribution to journalComment/debate

DNA polymorphism and molecular pathology of the human globin gene clusters

Antonarakis, S. E., Kazazian, H. H. & Orkin, S. H., Jan 1 1985, In : Human genetics. 69, 1, p. 1-14 14 p.

Research output: Contribution to journalReview article

Evidence supporting a single origin of the β(C)-globin gene in blacks

Boehm, C. D., Dowling, C. E., Antonarakis, S. E., Honig, G. R. & Kazazian, H. H., Dec 1 1985, In : American journal of human genetics. 37, 4, p. 771-777 7 p.

Research output: Contribution to journalArticle

Gene probes: Application to prenatal and postnatal diagnosis of genetic disease

Kazazian, H. H., Dec 1 1985, In : Clinical chemistry. 31, 9, p. 1509-1513 5 p.

Research output: Contribution to journalArticle

Hemophilia A Detection of Molecular Defects and of Carriers by DNA Analysis

Antonarakis, S. E., Waber, P. G., Kittur, S. D., Patel, A. S., Kazazian, H. H., Mellis, M. A., Counts, R. B., Stamatoyannopoulos, G., Bowie, E. J. W., Fass, D. N., Pittman, D. D., Wozney, J. M. & Toole, J. J., Oct 3 1985, In : New England Journal of Medicine. 313, 14, p. 842-848 7 p.

Research output: Contribution to journalArticle

Huntington's disease: Two families with differing clinical features show linkage to the G8 probe

Folstein, S. E., Phillips, J. A., Meyers, D. A., Chase, G. A., Abbott, M. H., Franz, M. L., Waber, P. G., Kazazian, H. H., Conneally, P. M., Hobbs, W., Tanzi, R., Faryniarz, A., Gibbons, K. & Gusella, J., 1985, In : Science. 229, 4715, p. 776-779 4 p.

Research output: Contribution to journalReview article

Linkage map of the short arm of human chomosome 11: Location of the genes for catalase, calcitonin, and insulin-like growth factor II

Kittur, S. D., Hoppener, J. W. M., Antonarakis, S. E., Daniels, J. D., Meyers, D. A., Maestri, N. E., Jansen, M., Korneluk, R. G., Nelkin, B. D. & Kazazian, H. H., 1985, In : Proceedings of the National Academy of Sciences of the United States of America. 82, 15, p. 5064-5067 4 p.

Research output: Contribution to journalArticle

Linkage Map on Chromosome 21q and the Association of a DNA Haplotype with a Propensity to Nondisjunction and Trisomy 21

ANTONARAKIS, STYLIANOS. E., KITTUR, SMITA. D., METAXOTOU, CATERINA., BARTSOCAS, CHRISTOS., KITSIOU, SOPHIA., WATKINS, PAUL. C., PATEL, ACHYUT. S., WARREN, ANDREW. C., GUSELLA, JAMES. F., GRONER, YORAM., CHAKRAVARTI, ARAVINDA., MEYERS, DEBORAH. A. & KAZAZIAN, HAIG. H., Jun 1985, In : Annals of the New York Academy of Sciences. 450, 1, p. 95-107 13 p.

Research output: Contribution to journalArticle

Molecular pathology of the β-globin gene cluster

Kazazian, H. H., 1985, In : Trends in Neurosciences. 8, C, p. 192-200 9 p.

Research output: Contribution to journalArticle

PRENATAL DIAGNOSIS OF HAEMOPHILIA A BY FACTOR VIII GENE ANALYSIS

Antonarakis, S. E., Copeland, K. L., Carpenter, R. J., Carta, C. A., Hoyer, L. W., Caskey, C. T., Toole, J. J. & Kazazian, H. H., Jun 22 1985, In : The Lancet. 325, 8443, p. 1407-1409 3 p.

Research output: Contribution to journalArticle

Prenatal diagnosis of hemoglobinopathies by DNA analysis

Boehm, C., Kazazian, H. H. & Rowley, P. T., 1985, In : Critical Reviews in Oncology and Hematology. 4, 2, p. 155-167 13 p.

Research output: Contribution to journalArticle

Prenatal Diagnosis of Hemoglobinopathies by DNA Analysis

KAZAZIAN, HAIG. H., BOEHM, CORINNE. D. & DOWLING, CAROL. E., Jun 1985, In : Annals of the New York Academy of Sciences. 445, 1, p. 337-348 12 p.

Research output: Contribution to journalArticle

Report of the committee on the genetic constitution of chromosomes 10, 11, and 12

Grzeschik, K. H. & Kazazian, H., 1985, In : Birth Defects: Original Article Series. 21, 4, p. 179-205 27 p.

Research output: Contribution to journalArticle

Report of the committee on the genetic constitution of chromosomes 10, 11, and 12

Grzeschik, K. H. & Kazazian, H. H., Jan 1 1985, In : Cytogenetic and Genome Research. 40, 1-4, p. 179-205 27 p.

Research output: Contribution to journalArticle

Ring Chromosome 21: Characterization of DNA Sequences at Sites of Breakage and Reunion

KAZAZIAN, HAIG. H., ANTONARAKIS, STYLIANOS. E., WONG, CORINNE., TRUSKO, STEPHEN. P., Stetten, G., OLIVER, MARK., POTTER, MICHAEL. J., GUSELLA, JAMES. F. & WATKINS, PAUL. C., Jun 1985, In : Annals of the New York Academy of Sciences. 450, 1, p. 33-42 10 p.

Research output: Contribution to journalArticle

Sequences of G gamma, A gamma, and beta genes of the Greek (A gamma) HPFH mutant: evidence for a distal CCAAT box mutation in the A gamma gene.

Gelinas, R., Yagi, M., Endlich, B., Lotshaw, C., Kazazian, H. H. & Stamatoyannopoulos, G., Jan 1 1985, In : Progress in clinical and biological research. 191, p. 125-139 15 p.

Research output: Contribution to journalReview article

Thalassemia due to a mutation in the cleavage-polyadenylation signal of the human beta-globin gene.

Orkin, S. H., Cheng, T. C., Antonarakis, S. E. & Kazazian, H. H., Feb 1985, In : The EMBO journal. 4, 2, p. 453-456 4 p.

Research output: Contribution to journalArticle

Open Access

The nature of mutation

Kazazian, H. H., Jan 1 1985, In : Hospital practice. 20, 2, p. 55-69 15 p.

Research output: Contribution to journalReview article

β-Thalassemia in Chinese. Analysis of polymorphic restriction site haplotypes in the β-globin gene cluster

Huang, S. Z., Kazazian, H. H., Waber, P. G., Luo, H. Y., Cai, R. L. & Wang, M. Q., Dec 1 1985, In : Chinese medical journal. 98, 12, p. 881-886 6 p.

Research output: Contribution to journalArticle

1984

Base substitution at position -88 in a β-thalassemic globin gene. Further evidence for the role of distal promoter element ACACCC

Orkin, S. H., Antonarakis, S. E. & Kazazian, H. H., Jan 1 1984, In : Journal of Biological Chemistry. 259, 14, p. 8679-8681 3 p.

Research output: Contribution to journalArticle