Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Mycobacterium tuberculosis Medicine & Life Sciences
Peptidyl Transferases Medicine & Life Sciences
Tuberculosis Medicine & Life Sciences
Carbapenems Medicine & Life Sciences
Peptidoglycan Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Mycobacterium Medicine & Life Sciences
meropenem Medicine & Life Sciences

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Research Output 2003 2017

Combinations of avibactam and carbapenems exhibit enhanced potencies against drug-resistant Mycobacterium abscessus

Kaushik, A., Gupta, C., Fisher, S., Story-Roller, E., Galanis, C., Parrish, N. & Lamichhane, G. May 1 2017 In : Future Microbiology. 12, 6, p. 473-480 8 p.

Research output: Contribution to journalArticle

Carbapenems
Mycobacterium
Pharmaceutical Preparations
beta-Lactams
Infection

Computational model for the acylation step of the β-lactam ring: Potential application for L,D-transpeptidase 2 in mycobacterium tuberculosis

Fakhar, Z., Govender, T., Lamichhane, G., Maguire, G. E. M., Kruger, H. G. & Honarparvar, B. Jan 15 2017 In : Journal of Molecular Structure. 1128, p. 94-102 9 p.

Research output: Contribution to journalArticle

Peptidyl Transferases
Acylation
beta-Lactams
Carbapenems
Molecular orbitals

Differential flap dynamics in l,d-transpeptidase2 from mycobacterium tuberculosis revealed by molecular dynamics

Fakhar, Z., Govender, T., Maguire, G. E. M., Lamichhane, G., Walker, R. C., Kruger, H. G. & Honarparvar, B. 2017 In : Molecular BioSystems. 13, 6, p. 1223-1234 12 p.

Research output: Contribution to journalArticle

Carbapenems
meropenem
Molecular Dynamics Simulation
Mycobacterium tuberculosis
Ligands

Drug resistance mechanisms and novel drug targets for tuberculosis therapy

Islam, M. M., Hameed, H. M. A., Mugweru, J., Chhotaray, C., Wang, C., Tan, Y., Liu, J., Li, X., Tan, S., Ojima, I., Yew, W. W., Nuermberger, E., Lamichhane, G. & Zhang, T. Jan 20 2017 In : Journal of Genetics and Genomics. 44, 1, p. 21-37 17 p.

Research output: Contribution to journalReview article

Drug Resistance
Tuberculosis
Pharmaceutical Preparations
Multidrug-Resistant Tuberculosis
Mycobacterium tuberculosis

Inhibition of innate immune cytosolic surveillance by an M.Tuberculosis phosphodiesterase

Dey, R. J., Dey, B., Zheng, Y., Cheung, L. S., Zhou, J., Sayre, D., Kumar, P., Guo, H., Lamichhane, G., Sintim, H. O. & Bishai, W. R. Feb 1 2017 In : Nature Chemical Biology. 13, 2, p. 210-217 8 p.

Research output: Contribution to journalArticle

Phosphoric Diester Hydrolases
Interferon Type I
Tuberculosis
Mycobacterium Infections
Phosphodiesterase Inhibitors