Gyanu Lamichhane

ASSOCIATE PROFESSOR

20032018
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  • 5 Similar Profiles
Mycobacterium tuberculosis Medicine & Life Sciences
Peptidyl Transferases Medicine & Life Sciences
Carbapenems Medicine & Life Sciences
Tuberculosis Medicine & Life Sciences
Peptidoglycan Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Mycobacterium Medicine & Life Sciences
meropenem Medicine & Life Sciences

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Research Output 2003 2018

Have we realized the full potential of β-lactams for treating drug-resistant TB?

Story-Roller, E. & Lamichhane, G., Sep 1 2018, In : IUBMB Life. 70, 9, p. 881-888 8 p.

Research output: Contribution to journalReview article

beta-Lactams
Pharmaceutical Preparations
Anti-Bacterial Agents
Bacteria

Molecular insight on the non-covalent interactions between carbapenems and l,d-transpeptidase 2 from Mycobacterium tuberculosis: ONIOM study

Ntombela, T., Fakhar, Z., Ibeji, C. U., Govender, T., Maguire, G. E. M., Lamichhane, G., Kruger, H. G. & Honarparvar, B., May 29 2018, (Accepted/In press) In : Journal of Computer-Aided Molecular Design. p. 1-15 15 p.

Research output: Contribution to journalArticle

Peptidyl Transferases
tuberculosis
Carbapenems
Platelets
Mycobacterium tuberculosis

Combinations of avibactam and carbapenems exhibit enhanced potencies against drug-resistant Mycobacterium abscessus

Kaushik, A., Gupta, C., Fisher, S., Story-Roller, E., Galanis, C., Parrish, N. & Lamichhane, G., May 1 2017, In : Future Microbiology. 12, 6, p. 473-480 8 p.

Research output: Contribution to journalArticle

Carbapenems
Mycobacterium
Pharmaceutical Preparations
beta-Lactams
Infection

Computational model for the acylation step of the β-lactam ring: Potential application for L,D-transpeptidase 2 in mycobacterium tuberculosis

Fakhar, Z., Govender, T., Lamichhane, G., Maguire, G. E. M., Kruger, H. G. & Honarparvar, B., Jan 15 2017, In : Journal of Molecular Structure. 1128, p. 94-102 9 p.

Research output: Contribution to journalArticle

Peptidyl Transferases
Acylation
beta-Lactams
Carbapenems
Molecular orbitals

Differential flap dynamics in l,d-transpeptidase2 from mycobacterium tuberculosis revealed by molecular dynamics

Fakhar, Z., Govender, T., Maguire, G. E. M., Lamichhane, G., Walker, R. C., Kruger, H. G. & Honarparvar, B., 2017, In : Molecular BioSystems. 13, 6, p. 1223-1234 12 p.

Research output: Contribution to journalArticle

Carbapenems
meropenem
Molecular Dynamics Simulation
Mycobacterium tuberculosis
Ligands