Gyanu Lamichhane

ASSOCIATE PROFESSOR

20032019
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 8 Similar Profiles
Mycobacterium tuberculosis Medicine & Life Sciences
Peptidyl Transferases Medicine & Life Sciences
Tuberculosis Medicine & Life Sciences
Carbapenems Medicine & Life Sciences
Peptidoglycan Medicine & Life Sciences
Mycobacterium Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
beta-Lactams Medicine & Life Sciences

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Research Output 2003 2019

Inhibition mechanism of L,D-transpeptidase 5 in presence of the β-lactams using ONIOM method

Tolufashe, G. F., Sabe, V. T., Ibeji, C. U., Lawal, M. M., Govender, T., Maguire, G. E. M., Lamichhane, G., Kruger, H. G. & Honarparvar, B., Mar 1 2019, In : Journal of Molecular Graphics and Modelling. 87, p. 204-210 7 p.

Research output: Contribution to journalArticle

Peptidyl Transferases
acylation
beta-Lactams
Acylation
tuberculosis

Activities of dual combinations of antibiotics against multidrug-resistant nontuberculous mycobacteria recovered from patients with cystic fibrosis

Schwartz, M., Fisher, S., Story-Roller, E., Lamichhane, G. & Parrish, N. M., Oct 1 2018, In : Microbial Drug Resistance. 24, 8, p. 1191-1197 7 p.

Research output: Contribution to journalArticle

Nontuberculous Mycobacteria
Cystic Fibrosis
Anti-Bacterial Agents
Microbial Sensitivity Tests
Mycobacterium chelonae

Have we realized the full potential of β-lactams for treating drug-resistant TB?

Story-Roller, E. & Lamichhane, G., Sep 1 2018, In : IUBMB Life. 70, 9, p. 881-888 8 p.

Research output: Contribution to journalReview article

beta-Lactams
Pharmaceutical Preparations
Anti-Bacterial Agents
Bacteria

Inhibition of Mycobacterium tuberculosis L,D-Transpeptidase 5 by Carbapenems: MD and QM/MM Mechanistic Studies

Tolufashe, G. F., Halder, A. K., Ibeji, C. U., Lawal, M. M., Ntombela, T., Govender, T., Maguire, G. E. M., Lamichhane, G., Kruger, H. G. & Honarparvar, B., Dec 28 2018, In : ChemistrySelect. 3, 48, p. 13603-13612 10 p.

Research output: Contribution to journalArticle

Peptidyl Transferases
meropenem
Carbapenems
Molecular dynamics
Imipenem

Molecular insight on the non-covalent interactions between carbapenems and l,d-transpeptidase 2 from Mycobacterium tuberculosis: ONIOM study

Ntombela, T., Fakhar, Z., Ibeji, C. U., Govender, T., Maguire, G. E. M., Lamichhane, G., Kruger, H. G. & Honarparvar, B., May 29 2018, (Accepted/In press) In : Journal of Computer-Aided Molecular Design. p. 1-15 15 p.

Research output: Contribution to journalArticle

Peptidyl Transferases
tuberculosis
Carbapenems
Mycobacterium tuberculosis
Hydrogen bonds