Research Output 2001 2017

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2017

Detection and Quantification of Hydrogen Peroxide in Aqueous Solutions Using Chemical Exchange Saturation Transfer

Ryoo, D., Xu, X., Li, Y., Tang, J. A., Zhang, J., Van Zijl, P. C. M. & Liu, G. Jul 18 2017 In : Analytical Chemistry. 89, 14, p. 7758-7764 7 p.

Research output: Research - peer-reviewArticle

Saturation (materials composition)
Hydrogen Peroxide
Ion exchange
Nuclear magnetic resonance
Magnetic resonance

Detection of dynamic substrate binding using MRI

Yadav, N. N., Yang, X., Li, Y., Li, W., Liu, G. & Van Zijl, P. C. M. Dec 1 2017 In : Scientific Reports. 7, 1, 10138

Research output: Research - peer-reviewArticle

Protons
Magnetic Resonance Imaging
Water
Caffeine
Radio

GlucoCEST magnetic resonance imaging in vivo may be diagnostic of acute renal allograft rejection

Kentrup, D., Bovenkamp, P., Busch, A., Schuette-Nuetgen, K., Pawelski, H., Pavenstädt, H., Schlatter, E., Herrmann, K. H., Reichenbach, J. R., Löffler, B., Heitplatz, B., Van Marck, V., Yadav, N. N., Liu, G., van Zijl, P. C. M., Reuter, S. & Hoerr, V. Sep 1 2017 In : Kidney International. 92, 3, p. 757-764 8 p.

Research output: Research - peer-reviewArticle

Allografts
Magnetic Resonance Imaging
Kidney
Glucose
T-Lymphocytes

Monitoring tumor response to antivascular therapy using non-contrast intravoxel incoherent motion diffusion-weighted MRI

Shi, C., Liu, D., Xiao, Z., Zhang, D., Liu, G., Liu, G., Chen, H. & Luo, L. Jul 1 2017 In : Cancer Research. 77, 13, p. 3491-3501 11 p.

Research output: Research - peer-reviewArticle

Diffusion Magnetic Resonance Imaging
Neoplasms
Therapeutics
Non-Small Cell Lung Carcinoma
Perfusion

One-Component Supramolecular Filament Hydrogels as Theranostic Label-Free Magnetic Resonance Imaging Agents

Lock, L. L., Li, Y., Mao, X., Chen, H., Staedtke, V., Bai, R., Ma, W., Lin, R., Li, Y., Liu, G. & Cui, H. Jan 24 2017 In : ACS Nano. 11, 1, p. 797-805 9 p.

Research output: Research - peer-reviewArticle

Hydrogels
Magnetic resonance
Labels
Imaging techniques
Pharmaceutical Preparations
2016

CEST-MRI detects metabolite levels altered by breast cancer cell aggressiveness and chemotherapy response

Chan, K. W. Y., Jiang, L., Cheng, M., Wijnen, J. P., Liu, G., Huang, P., van Zijl, P. C. M., Mcmahon, M. T. & Glunde, K. 2016 (Accepted/In press) In : NMR in Biomedicine.

Research output: Research - peer-reviewArticle

Chemotherapy
Metabolites
Magnetic resonance imaging
Cells
Breast Neoplasms

CEST theranostics: Label-free MR imaging of anticancer drugs

Li, Y., Chen, H., Xu, J., Yadav, N. N., Chan, K. W. Y., Luo, L., McMahon, M. T., Vogelstein, B., Van Zijl, P. C. M., Zhou, S. & Liu, G. 2016 In : Oncotarget. 7, 6, p. 6369-6378 10 p.

Research output: Research - peer-reviewArticle

Pharmaceutical Preparations
Theranostic Nanomedicine
Neoplasms
gemcitabine
Folic Acid Antagonists

Developing imidazoles as CEST MRI pH sensors

Yang, X., Song, X., Ray Banerjee, S., Li, Y., Byun, Y., Liu, G., Bhujwalla, Z. M., Pomper, M. G. & McMahon, M. T. Jul 1 2016 In : Contrast Media and Molecular Imaging. 11, 4, p. 304-312 9 p.

Research output: Research - peer-reviewArticle

Imidazoles
Magnetic Resonance Imaging
Heterocyclic Compounds
Intravenous Administration
Hydrogen

Imaging the DNA alkylator melphalan by CEST MRI: An advanced approach to theranostics

Ngen, E. J., Bar-Shir, A., Jablonska, A., Liu, G., Song, X., Ansari, R., Bulte, J. W. M., Janowski, M., Pearl, M., Walczak, P. & Gilad, A. A. Sep 6 2016 In : Molecular Pharmaceutics. 13, 9, p. 3043-3053 11 p.

Research output: Research - peer-reviewArticle

Melphalan
Alkylating Agents
Magnetic Resonance Imaging
DNA
Theranostic Nanomedicine

Intravoxel incoherent motion diffusion weighted imaging in the assessment of the renal functional alternation in contrast-induced acute kidney injury models

Zhang, B., Chen, W., Liang, L., Liu, G., Chan, K. W. Y., Li, Y., Zheng, J., Liang, C. & Zhang, S. Mar 10 2016 In : Chinese Journal of Radiology (China). 50, 3, p. 180-185 6 p.

Research output: Research - peer-reviewArticle

Acute Kidney Injury
Kidney
Injections
Diatrizoate Meglumine
Vasodilator Agents

Label-free CEST MRI detection of citicoline-liposome drug delivery in ischemic stroke

Liu, H., Jablonska, A., Li, Y., Cao, S., Liu, D., Chen, H., Van Zijl, P. C. M., Bulte, J. W. M., Janowski, M., Walczak, P. & Liu, G. 2016 In : Theranostics. 6, 10, p. 1588-1600 13 p.

Research output: Research - peer-reviewArticle

Cytidine Diphosphate Choline
Liposomes
Stroke
Pharmaceutical Preparations
6-chloro-3,5-diaminopyrazine-3-carboxamide

On-resonance variable delay multipulse scheme for imaging of fast-exchanging protons and semisolid macromolecules

Xu, J., Chan, K. W. Y., Xu, X., Yadav, N., Liu, G. & van Zijl, P. C. M. 2016 (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Research - peer-reviewArticle

Protons
Water
Brain
Gray Matter
Creatine
2015
Blood Volume
Blood-Brain Barrier
Brain Neoplasms
Glucose
Area Under Curve

Establishing the lysine-rich protein CEST reporter gene as a CEST MR imaging detector for oncolytic virotherapy

Farrar, C. T., Buhrman, J. S., Liu, G., Kleijn, A., Lamfers, M. L. M., McMahon, M. T., Gilad, A. A. & Fulci, G. Jun 1 2015 In : Radiology. 275, 3, p. 746-754 9 p.

Research output: Research - peer-reviewArticle

Oncolytic Virotherapy
Reporter Genes
Lysine
Magnetic Resonance Imaging
Proteins

Label-free in vivo molecular imaging of underglycosylated mucin-1 expression in tumour cells

Song, X., Airan, R. D., Arifin, D. R., Bar-Shir, A., Kadayakkara, D. K., Liu, G., Gilad, A. A., Van Zijl, P. C. M., McMahon, M. T. & Bulte, J. W. M. Mar 30 2015 In : Nature Communications. 6, 6719

Research output: Research - peer-reviewArticle

Molecular imaging
Mucin-1
Labels
Tumors
Cells

To evaluate the damage of renal function in CIAKI rats at 3T: Using ASL and BOLD MRI

Chen, W. B., Liang, L., Zhang, B., Liu, C. L., Liu, H. J., Luo, H. Y., Zeng, Q. X., Liang, C. H., Liu, G. S. & Zhang, S. X. 2015 In : BioMed Research International. 2015, 593060

Research output: Research - peer-reviewArticle

Magnetic resonance imaging
Labeling
Rats
Blood
Oxygen

Using intravoxel incoherent motion MR imaging to study the renal pathophysiological process of contrast-induced acute kidney injury in rats: Comparison with conventional DWI and arterial spin labelling

Liang, L., Chen, W. B., Chan, K. W. Y., Li, Y. G., Zhang, B., Liang, C. H., Liu, G. S. & Zhang, S. X. Sep 15 2015 (Accepted/In press) In : European Radiology.

Research output: Research - peer-reviewArticle

Acute Kidney Injury
Kidney
Renal Circulation
Perfusion
Creatinine
2014

A diaCEST MRI approach for monitoring liposomal accumulation in tumors

Chan, K. W. Y., Yu, T., Qiao, Y., Liu, Q., Yang, M., Patel, H., Liu, G., Kinzler, K. W., Vogelstein, B., Bulte, J. W. M., Van Zijl, P. C. M., Hanes, J., Zhou, S. & McMahon, M. T. Apr 28 2014 In : Journal of Controlled Release. 180, 1, p. 51-59 9 p.

Research output: Research - peer-reviewArticle

Liposomes
Neoplasms
Tumor Necrosis Factor-alpha
barbituric acid
In Vitro Techniques

Human protamine-1 as an mri reporter gene based on chemical exchange

Bar-Shir, A., Liu, G., Chan, K. W. Y., Oskolkov, N., Song, X., Yadav, N. N., Walczak, P., McMahon, M. T., Van Zijl, P. C. M., Bulte, J. W. M. & Gilad, A. A. Jan 17 2014 In : ACS Chemical Biology. 9, 1, p. 134-138 5 p.

Research output: Research - peer-reviewArticle

Protamines
Genes
Reporter Genes
Magnetic resonance imaging
Arginine
Alginate
Magnetic resonance imaging
Magnetization
Capsules
alginic acid

Multiwalled nanotubes formed by catanionic mixtures of drug amphiphiles

Lin, Y. A., Cheetham, A. G., Zhang, P., Ou, Y. C., Li, Y., Liu, G., Hermida-Merino, D., Hamley, I. W. & Cui, H. Dec 23 2014 In : ACS Nano. 8, 12, p. 12690-12700 11 p.

Research output: Research - peer-reviewArticle

Amphiphiles
Nanotubes
Pharmaceutical Preparations
nanotubes
drugs
Magnetic resonance imaging
Water
Temperature
Protons
Fats

Vaginal Delivery of Paclitaxel via Nanoparticles with Non-Mucoadhesive Surfaces Suppresses Cervical Tumor Growth

Yang, M., Yu, T., Wang, Y. Y., Lai, S. K., Zeng, Q., Miao, B., Tang, B. C., Simons, B. W., Ensign, L. M., Liu, G., Chan, K. W. Y., Juang, C. Y., Mert, O., Wood, J., Fu, J., Mcmahon, M. T., Wu, T. C., Hung, C. F. & Hanes, J. 2014 In : Advanced healthcare materials. 3, 7, p. 1044-1052 9 p.

Research output: Research - peer-reviewArticle

Paclitaxel
Nanoparticles
Growth
Neoplasms
Tumors
2013

Metal ion sensing using ion chemical exchange saturation transfer 19F magnetic resonance imaging

Bar-Shir, A., Gilad, A. A., Chan, K. W. Y., Liu, G., Van Zijl, P. C. M., Bulte, J. W. M. & McMahon, M. T. Aug 21 2013 In : Journal of the American Chemical Society. 135, 33, p. 12164-12167 4 p.

Research output: Research - peer-reviewArticle

Chemical shift
Magnetic resonance
Metal ions
Ion exchange
Ions

MRI-detectable pH nanosensors incorporated into hydrogels for in vivo sensing of transplanted-cell viability

Chan, K. W. Y., Liu, G., Song, X., Kim, H., Yu, T., Arifin, D. R., Gilad, A. A., Hanes, J., Walczak, P., Van Zijl, P. C. M., Bulte, J. W. M. & McMahon, M. T. Mar 2013 In : Nature Materials. 12, 3, p. 268-275 8 p.

Research output: Research - peer-reviewArticle

Nanosensors
Hydrogels
Magnetic resonance
Cells
Imaging techniques
Bovine Serum Albumin
Liposomes
Artifacts
Contrast Media
Cerebrospinal Fluid

Nuts and bolts of chemical exchange saturation transfer MRI

Liu, G., Song, X., Chan, K. W. Y. & Mcmahon, M. T. Jul 2013 In : NMR in Biomedicine. 26, 7, p. 810-828 19 p.

Research output: Research - peer-reviewArticle

Magnetic resonance imaging
Imaging techniques
Processing
Technology Transfer
Molecular Imaging
Salicylic acid
Magnetic resonance imaging
Ion exchange
Protons
Water

Synthesis of a probe for monitoring HSV1-tk reporter gene expression using chemical exchange saturation transfer MRI

Bar-Shir, A., Liu, G., Greenberg, M. M., Bulte, J. W. M. & Gilad, A. A. 2013 In : Nature Protocols. 8, 12, p. 2380-2391 12 p.

Research output: Research - peer-reviewArticle

Viruses
Gene expression
Magnetic resonance imaging
Monitoring
5,6-dihydro-5-methylthymidine

Transforming thymidine into a magnetic resonance imaging probe for monitoring gene expression

Bar-Shir, A., Liu, G., Liang, Y., Yadav, N. N., McMahon, M. T., Walczak, P., Nimmagadda, S., Pomper, M. G., Tallman, K. A., Greenberg, M. M., Van Zijl, P. C. M., Bulte, J. W. M. & Gilad, A. A. Jan 30 2013 In : Journal of the American Chemical Society. 135, 4, p. 1617-1624 8 p.

Research output: Research - peer-reviewArticle

Magnetic resonance
Gene expression
Thymidine
Imaging techniques
Monitoring
2012

CEST phase mapping using a length and offset varied saturation (LOVARS) scheme

Song, X., Gilad, A. A., Joel, S., Liu, G., Bar-Shir, A., Liang, Y., Gorelik, M., Pekar, J. J., Van Zijl, P. C. M., Bulte, J. W. M. & McMahon, M. T. Oct 2012 In : Magnetic Resonance in Medicine. 68, 4, p. 1074-1086 13 p.

Research output: Research - peer-reviewArticle

Noise
Gliosarcoma
Contrast Sensitivity
Molecular Imaging
Gadolinium

Imaging in vivo extracellular pH with a single paramagnetic chemical exchange saturation transfer magnetic resonance imaging contrast agent

Liu, G., Li, Y., Sheth, V. R. & Pagel, M. D. Jan 2012 In : Molecular Imaging. 11, 1, p. 47-57 11 p.

Research output: Research - peer-reviewArticle

magnetic resonance
saturation
Contrast Media
Magnetic Resonance Imaging
Magnetic resonance

Improved pH measurements with a single PARACEST MRI contrast agent

Sheth, V. R., Liu, G., Li, Y. & Pagel, M. D. Jan 2012 In : Contrast Media and Molecular Imaging. 7, 1, p. 26-34 9 p.

Research output: Research - peer-reviewArticle

Contrast Media
Temperature
Therapeutic Uses
Magnetic Fields
Amides

In vivo multicolor molecular MR imaging using diamagnetic chemical exchange saturation transfer liposomes

Liu, G., Moake, M., Har-El, Y. E., Long, C. M., Chan, K. W. Y., Cardona, A., Jamil, M., Walczak, P., Gilad, A. A., Sgouros, G., Van Zijl, P. C. M., Bulte, J. W. M. & McMahon, M. T. Apr 2012 In : Magnetic Resonance in Medicine. 67, 4, p. 1106-1113 8 p.

Research output: Research - peer-reviewArticle

Molecular Imaging
Liposomes
Contrast Media
Glycogen
Lysine

MRI biosensor for protein kinase A encoded by a single synthetic gene

Airan, R. D., Bar-Shir, A., Liu, G., Pelled, G., McMahon, M. T., Van Zijl, P. C. M., Bulte, J. W. M. & Gilad, A. A. Dec 2012 In : Magnetic Resonance in Medicine. 68, 6, p. 1919-1923 5 p.

Research output: Research - peer-reviewArticle

Synthetic Genes
Biosensing Techniques
Cyclic AMP-Dependent Protein Kinases
Protein Kinases
Phosphorylation

Natural D -glucose as a biodegradable MRI contrast agent for detecting cancer

Chan, K. W. Y., McMahon, M. T., Kato, Y., Liu, G., Bulte, J. W. M., Bhujwalla, Z. M., Artemov, D. & Van Zijl, P. C. M. Dec 2012 In : Magnetic Resonance in Medicine. 68, 6, p. 1764-1773 10 p.

Research output: Research - peer-reviewArticle

Contrast Media
Glucose
Neoplasms
Hydroxyl Radical
Protons
2011

A self-calibrating PARACEST MRI contrast agent that detects esterase enzyme activity

Li, Y., Sheth, V. R., Liu, G. & Pagel, M. D. Jul 2011 In : Contrast Media and Molecular Imaging. 6, 4, p. 219-228 10 p.

Research output: Research - peer-reviewArticle

Esterases
Contrast Media
Biomarkers
Enzymes
Temperature

Monitoring enzyme activity using a diamagnetic chemical exchange saturation transfer magnetic resonance imaging contrast agent

Liu, G., Liang, Y., Bar-Shir, A., Chan, K. W. Y., Galpoththawela, C. S., Bernard, S. M., Tse, T., Yadav, N. N., Walczak, P., McMahon, M. T., Bulte, J. W. M., Van Zijl, P. C. M. & Gilad, A. A. Oct 19 2011 In : Journal of the American Chemical Society. 133, 41, p. 16326-16329 4 p.

Research output: Research - peer-reviewArticle

Enzyme activity
Magnetic resonance
Contrast Media
Imaging techniques
Monitoring

Multimodal imaging of sustained drug release from 3-D poly(propylene fumarate) (PPF) scaffolds

Choi, J., Kim, K., Kim, T., Liu, G., Bar-Shir, A., Hyeon, T., McMahon, M. T., Bulte, J. W. M., Fisher, J. P. & Gilad, A. A. Dec 10 2011 In : Journal of Controlled Release. 156, 2, p. 239-245 7 p.

Research output: Research - peer-reviewArticle

Multimodal Imaging
Pharmaceutical Preparations
poly(propylene fumarate)
Drug Liberation
Fumarates
2010
Contrast Media
Water
Plastics
High-Throughput Screening Assays
Magnetic Fields
2009

Paracest mri with improved temporal resolution

Liu, G., Ali, M. M., Yoo, B., Griswold, M. A., Tkach, J. A. & Pagel, M. D. Feb 2009 In : Magnetic Resonance in Medicine. 61, 2, p. 399-408 10 p.

Research output: Research - peer-reviewArticle

Molecular Imaging
Contrast Media
In Vitro Techniques

Using two chemical exchange saturation transfer magnetic resonance imaging contrast agents for molecular imaging studies

Ali, M. M., Liu, G., Shah, T., Flask, C. A. & Pagel, M. D. Jul 21 2009 In : Accounts of Chemical Research. 42, 7, p. 915-924 10 p.

Research output: Research - peer-reviewArticle

2007

Design and characterization of a new irreversible responsive PARACEST MRI contrast agent that detects nitric oxide

Liu, G., Li, Y. & Pagel, M. D. Dec 2007 In : Magnetic Resonance in Medicine. 58, 6, p. 1249-1256 8 p.

Research output: Research - peer-reviewArticle

Contrast Media
Nitric Oxide
Molecular Imaging
Amides
Amines
2004

Recent developments in the determination of urinary cancer biomarkers by capillary electrophoresis

Ma, Y., Liu, G., Du, M. & Stayton, I. Jun 2004 In : Electrophoresis. 25, 10-11, p. 1473-1484 12 p.

Research output: Research - peer-reviewArticle

Capillary electrophoresis
Tumor Biomarkers
Capillary Electrophoresis
Neoplasms
Biomarkers
Micellar Electrokinetic Capillary Chromatography
Polyamines
Cell Extracts
Catecholamines
Chromatography

The cytotoxicity and mechanisms of 1,2-naphthoquinone thiosemicarbazone and its metal derivatives against MCF-7 human breast cancer cells

Chen, J., Huang, Y. W., Liu, G., Afrasiabi, Z., Sinn, E., Padhye, S. & Ma, Y. May 15 2004 In : Toxicology and Applied Pharmacology. 197, 1, p. 40-48 9 p.

Research output: Research - peer-reviewArticle

Thiosemicarbazones
Cytotoxicity
Metals
Cells
Derivatives
2003

Separation and quantitation of short-chain coenzyme A's in biological samples by capillary electrophoresis

Liu, G., Chen, J., Che, P. & Ma, Y. Jan 1 2003 In : Analytical Chemistry. 75, 1, p. 78-82 5 p.

Research output: Research - peer-reviewArticle

Capillary electrophoresis
Coenzymes
Coenzyme A
High performance liquid chromatography
Metabolism
2002

Radiosensitization mechanism of riboflavin in vitro

Liu, G., Lu, C., Yao, S., Zhao, F., Li, Y., Meng, X., Gao, J., Cai, J., Zhang, L. & Chen, Z. 2002 In : Science in China. Series C, Life sciences / Chinese Academy of Sciences. 45, 4, p. 344-351 8 p.

Research output: Research - peer-reviewArticle

membrane
Riboflavin
In Vitro Techniques
riboflavin
microscopy

Research of radioprotection of EGCG

Liu, G., Yao, S., Ni, J., Zhao, F. & Meng, X. May 2002 In : Fushe Yanjiu yu Fushe Gongyi Xuebao/Journal of Radiation Research and Radiation Processing. 20, 2, p. 87 1 p.

Research output: Research - peer-reviewArticle