Gregory Carr

Assistant Professor

20082019
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where Gregory Carr is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Antidepressive Agents Medicine & Life Sciences
Catechol O-Methyltransferase Medicine & Life Sciences
Dopamine Medicine & Life Sciences
kappa Opioid Receptor Medicine & Life Sciences
Narcotic Antagonists Medicine & Life Sciences
Brain Medicine & Life Sciences
Schizophrenia Medicine & Life Sciences
Inbred WKY Rats Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2008 2019

Deletion of the vesicular monoamine transporter 1 (vmat1/slc18a1) gene affects dopamine signaling

Lohoff, F. W., Carr, G., Brookshire, B., Ferraro, T. N. & Lucki, I., Jun 1 2019, In : Brain research. 1712, p. 151-157 7 p.

Research output: Contribution to journalArticle

Vesicular Monoamine Transport Proteins
Dopamine
Frontal Lobe
Genes
Tyrosine 3-Monooxygenase

Development of a PC12 Cell Based Assay for Screening Catechol- O-methyltransferase Inhibitors

Zhang, G., Buchler, I. P., Depasquale, M., Wormald, M., Liao, G., Wei, H., Barrow, J. & Carr, G., Oct 16 2019, In : ACS Chemical Neuroscience. 10, 10, p. 4221-4226 6 p.

Research output: Contribution to journalArticle

PC12 Cells
Catechol O-Methyltransferase
Assays
Screening
Metabolites

Synthesis and Evaluation of Bicyclic Hydroxypyridones as Inhibitors of Catechol O-Methyltransferase

Ernst, G., Akuma, D., Au, V., Buchler, I. P., Byers, S., Carr, G. V., Defays, S., De León, P., Demaude, T., Depasquale, M., Durieu, V., Huang, Y., Jigorel, E., Kimos, M., Kolobova, A., Montel, F., Moureau, F., Poslusney, M., Swinnen, D., Vandergeten, M. C. & 5 others, Van Houtvin, N., Wei, H., White, N., Wood, M. & Barrow, J. C., Jan 1 2019, (Accepted/In press) In : ACS Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

Rats
Pyridones
Catechol O-Methyltransferase
Pharmacokinetics
Biomarkers

Optimization of 8-Hydroxyquinolines as Inhibitors of Catechol O-Methyltransferase

Buchler, I., Akuma, D., Au, V., Carr, G., De León, P., Depasquale, M., Ernst, G., Huang, Y., Kimos, M., Kolobova, A., Poslusney, M., Wei, H., Swinnen, D., Montel, F., Moureau, F., Jigorel, E., Schulze, M. S. E. D., Wood, M. & Barrow, J., Nov 8 2018, In : Journal of Medicinal Chemistry. 61, 21, p. 9647-9665 19 p.

Research output: Contribution to journalArticle

Oxyquinoline
Dopamine
Catalytic Domain
Quinolines
Catechol O-Methyltransferase

The dopamine D5 receptor is involved in working memory

Carr, G., Maltese, F., Sibley, D. R., Weinberger, D. & Papaleo, F., Oct 6 2017, In : Frontiers in Pharmacology. 8, OCT, 666.

Research output: Contribution to journalArticle

Dopamine D5 Receptors
Short-Term Memory
Pharmacology
Prefrontal Cortex
Knockout Mice