Gregg L Semenza

Professor

1984 …2019
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Fingerprint Dive into the research topics where Gregg L Semenza is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Hypoxia-Inducible Factor 1 Medicine & Life Sciences
Oxygen Medicine & Life Sciences
Vascular Endothelial Growth Factor A Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Homeostasis Medicine & Life Sciences
Cell Hypoxia Medicine & Life Sciences
Genes Medicine & Life Sciences
Hypoxia Medicine & Life Sciences

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Research Output 1984 2019

A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension

Dabral, S., Muecke, C., Valasarajan, C., Schmoranzer, M., Wietelmann, A., Semenza, G. L., Meister, M., Muley, T., Seeger-Nukpezah, T., Samakovlis, C., Weissmann, N., Grimminger, F., Seeger, W., Savai, R. & Pullamsetti, S. S., Dec 1 2019, In : Nature communications. 10, 1, 2130.

Research output: Contribution to journalArticle

Open Access
hypertension
hypoxia
Pulmonary Hypertension
Hypoxia-Inducible Factor 1
cancer

Editorial overview: Hypoxia

Sadek, H. A. & Semenza, G. L., Feb 1 2019, In : Current Opinion in Physiology. 7, p. iii-v

Research output: Contribution to journalEditorial

Hypoxia

Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature

Jiang, X., Tian, W., Tu, A. B., Pasupneti, S., Shuffle, E., Dahms, P., Zhang, P., Cai, H., Dinh, T. T., Liu, B., Cain, C., Giaccia, A. J., Butcher, E. C., Simon, M. C., Semenza, G. L. & Nicolls, M. R., Jan 22 2019, In : Circulation. 139, 4, p. 502-517 16 p.

Research output: Contribution to journalArticle

Microvessels
Maintenance
Angiopoietin-1
Blood Vessels
Hypoxia-Inducible Factor 1

Glutaminase 1 expression in colorectal cancer cells is induced by hypoxia and required for tumor growth, invasion, and metastatic colonization

Xiang, L., Mou, J., Shao, B., Wei, Y., Liang, H., Takano, N., Semenza, G. L. & Xie, G., Jan 1 2019, In : Cell Death and Disease. 10, 2, 40.

Research output: Contribution to journalArticle

Glutaminase
Colorectal Neoplasms
Growth
Neoplasms
Neoplasm Metastasis

HIF-1α is required for development of the sympathetic nervous system

Bohuslavova, R., Cerychova, R., Papousek, F., Olejnickova, V., Bartos, M., Görlach, A., Kolar, F., Sedmera, D., Semenza, G. L. & Pavlinkova, G., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 27, p. 13414-13423 10 p.

Research output: Contribution to journalArticle

Open Access
Hypoxia-Inducible Factor 1
Sympathetic Nervous System
Neurons
Chromaffin Cells
Gene Knockout Techniques