Research output per year
Research output per year
- 36 results
Search results
-
2023
Clinically relevant atovaquone-resistant human malaria parasites fail to transmit by mosquito
Balta, V. A., Stiffler, D., Sayeed, A., Tripathi, A. K., Elahi, R., Mlambo, G., Bakshi, R. P., Dziedzic, A. G., Jedlicka, A. E., Nenortas, E., Romero-Rodriguez, K., Canonizado, M. A., Mann, A., Owen, A., Sullivan, D. J., Prigge, S. T., Sinnis, P. & Shapiro, T. A., Dec 2023, In: Nature communications. 14, 1, 6415.Research output: Contribution to journal › Article › peer-review
Open Access -
Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness
Mok, S., Yeo, T., Hong, D., Shears, M. J., Ross, L. S., Ward, K. E., Dhingra, S. K., Kanai, M., Bridgford, J. L., Tripathi, A. K., Mlambo, G., Burkhard, A. Y., Ansbro, M. R., Fairhurst, K. J., Gil-Iturbe, E., Park, H., Rozenberg, F. D., Kim, J., Mancia, F., Fairhurst, R. M., & 4 others, Nov 10 2023, In: Science Advances. 9, 45, p. eadi2364Research output: Contribution to journal › Article › peer-review
Open Access -
2022
C-type lectin 4 regulates broad-spectrum melanization-based refractoriness to malaria parasites
Simões, M. L., Dong, Y., Mlambo, G. & Dimopoulos, G., Jan 2022, In: PLoS biology. 20, 1, e3001515.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Chemoprophylaxis vaccination with a Plasmodium liver stage autophagy mutant affords enhanced and long-lasting protection
Sahu, T., Gehrke, E. J., Flores-Garcia, Y., Mlambo, G., Romano, J. D. & Coppens, I., Dec 2021, In: npj Vaccines. 6, 1, 98.Research output: Contribution to journal › Article › peer-review
Open Access -
Plasmodium falciparum Pf77 and male development gene 1 as vaccine antigens that induce potent transmission-reducing antibodies
Tripathi, A. K., Oakley, M. S., Verma, N., Mlambo, G., Zheng, H., Meredith, S. M., Essuman, E., Puri, A., Skelton, R. A., Takeda, K., Majam, V., Quakyi, I. A., Locke, E., Morin, M., Miura, K., Long, C. A. & Kumar, S., Jun 9 2021, In: Science translational medicine. 13, 597, eabg2112.Research output: Contribution to journal › Article › peer-review
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2020
Plasmodium falciparum gametocyte culture and mosquito infection through artificial membrane feeding
Tripathi, A. K., Mlambo, G., Kanatani, S., Sinnis, P. & Dimopoulos, G., Jul 2020, In: Journal of Visualized Experiments. 2020, 161, p. 1-23 23 p., e61426.Research output: Contribution to journal › Article › peer-review
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2019
Generation of Transmission-Competent Human Malaria Parasites with Chromosomally-Integrated Fluorescent Reporters
McLean, K. J., Straimer, J., Hopp, C. S., Vega-Rodriguez, J., Small-Saunders, J. L., Kanatani, S., Tripathi, A., Mlambo, G., Dumoulin, P. C., Harris, C. T., Tong, X., Shears, M. J., Ankarklev, J., Kafsack, B. F. C., Fidock, D. A. & Sinnis, P., Dec 1 2019, In: Scientific reports. 9, 1, 13131.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
2018
A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission
Schleicher, T. R., Yang, J., Freudzon, M., Rembisz, A., Craft, S., Hamilton, M., Graham, M., Mlambo, G., Tripathi, A. K., Li, Y., Cresswell, P., Sinnis, P., Dimopoulos, G. & Fikrig, E., Dec 1 2018, In: Nature communications. 9, 1, 2908.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Aquaglyceroporin PbAQP is required for efficient progression through the liver stage of Plasmodium infection
Promeneur, D., Mlambo, G., Agre, P. & Coppens, I., Dec 1 2018, In: Scientific reports. 8, 1, 655.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Immunization with AgTRIO, a Protein in Anopheles Saliva, Contributes to Protection against Plasmodium Infection in Mice
Dragovic, S. M., Agunbiade, T. A., Freudzon, M., Yang, J., Hastings, A. K., Schleicher, T. R., Zhou, X., Craft, S., Chuang, Y. M., Gonzalez, F., Li, Y., Hrebikova, G., Tripathi, A., Mlambo, G., Almeras, L., Ploss, A., Dimopoulos, G. & Fikrig, E., Apr 11 2018, In: Cell Host and Microbe. 23, 4, p. 523-535.e5Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Long-acting injectable atovaquone nanomedicines for malaria prophylaxis
Bakshi, R. P., Tatham, L. M., Savage, A. C., Tripathi, A. K., Mlambo, G., Ippolito, M. M., Nenortas, E., Rannard, S. P., Owen, A. & Shapiro, T. A., Dec 1 2018, In: Nature communications. 9, 1, 315.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
Transcriptome analysis based detection of Plasmodium falciparum development in Anopheles stephensi mosquitoes
Oakley, M. S., Verma, N., Myers, T. G., Zheng, H., Locke, E., Morin, M. J., Tripathi, A. K., Mlambo, G. & Kumar, S., Dec 1 2018, In: Scientific reports. 8, 1, 11568.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2017
A no film slot blot for the detection of developing P. Falciparum oocysts in mosquitoes
Grabias, B., Verma, N., Zheng, H., Tripathi, A. K., Mlambo, G., Morin, M. J., Locke, E. & Kumar, S., Apr 2017, In: PloS one. 12, 4, 0174229.Research output: Contribution to journal › Article › peer-review
Open Access -
A novel gametocyte biomarker for superior molecular detection of the plasmodium falciparum infectious reservoirs
Essuman, E., Grabias, B., Verma, N., Chorazeczewski, J. K., Tripathi, A. K., Mlambo, G., Addison, E. A., Amoah, A. G. B., Quakyi, I., Oakley, M. S. & Kumar, S., Nov 15 2017, In: Journal of Infectious Diseases. 216, 10, p. 1264-1272 9 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Functional characterization of malaria parasites deficient in the K+ channel Kch2
Ellekvist, P., Mlambo, G., Kumar, N. & Klaerke, D. A., Nov 4 2017, In: Biochemical and Biophysical Research Communications. 493, 1, p. 690-696 7 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Immune regulation of plasmodium is anopheles species specific and infection intensity dependent
Simões, M. L., Mlambo, G., Tripathi, A., Dong, Y. & Dimopoulos, G., Sep 1 2017, In: mBio. 8, 5, e01631-17.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
2016
Functional genomic analyses of Enterobacter, Anopheles and Plasmodium reciprocal interactions that impact vector competence
Dennison, N. J., Saraiva, R. G., Cirimotich, C. M., Mlambo, G., Mongodin, E. F. & Dimopoulos, G., Aug 22 2016, In: Malaria journal. 15, 1, 425.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Molecular markers of radiation induced attenuation in intrahepatic plasmodium falciparum parasites
Oakley, M. S., Verma, N., Zheng, H., Anantharaman, V., Takeda, K., Gao, Y., Myers, T. G., Pham, P. T., Mahajan, B., Kumar, N., Sangweme, D., Tripathi, A. K., Mlambo, G., Aravind, L. & Kumar, S., Dec 2016, In: PloS one. 11, 12, e0166814.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Overexpression of Plasmodium berghei ATG8 by liver forms leads to cumulative defects in organelle dynamics and to generation of noninfectious merozoites
Voss, C., Ehrenman, K., Mlambo, G., Mishra, S., Kumar, K. A., Sacci, J. B., Sinnis, P. & Coppens, I., 2016, In: mBio. 7, 3, e00682-16.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
2015
A sensitive enhanced chemiluminescent-ELISA for the detection of Plasmodium falciparum circumsporozoite antigen in midguts of Anopheles stephensi mosquitoes
Grabias, B., Zheng, H., Mlambo, G., Tripathi, A. K. & Kumar, S., Jan 1 2015, In: Journal of Microbiological Methods. 108, p. 19-24 6 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
2014
Chromobacterium Csp_P Reduces Malaria and Dengue Infection in Vector Mosquitoes and Has Entomopathogenic and In Vitro Anti-pathogen Activities
Ramirez, J. L., Short, S. M., Bahia, A. C., Saraiva, R. G., Dong, Y., Kang, S., Tripathi, A., Mlambo, G. & Dimopoulos, G., Oct 1 2014, In: PLoS pathogens. 10, 10Research output: Contribution to journal › Article › peer-review
Open Access128 Scopus citations -
Exploring Anopheles gut bacteria for Plasmodium blocking activity
Bahia, A. C., Dong, Y., Blumberg, B. J., Mlambo, G., Tripathi, A., Benmarzouk-Hidalgo, O. J., Chandra, R. & Dimopoulos, G., Sep 2014, In: Environmental Microbiology. 16, 9, p. 2980-2994 15 p.Research output: Contribution to journal › Article › peer-review
Open Access77 Scopus citations -
Gametocytocidal screen identifies novel chemical classes with Plasmodium falciparum transmission blocking activity
Sanders, N. G., Sullivan, D. J., Mlambo, G., Dimopoulos, G. & Tripathi, A. K., Aug 26 2014, In: PloS one. 9, 8, e105817.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
2013
Functional evaluation of malaria Pfs25 DNA vaccine by in vivo electroporation in olive baboons
Kumar, R., Nyakundi, R., Kariuki, T., Ozwara, H., Nyamongo, O., Mlambo, G., Ellefsen, B., Hannaman, D. & Kumar, N., Jun 28 2013, In: Vaccine. 31, 31, p. 3140-3147 8 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
2012
Aberrant Sporogonic Development of Dmc1 (a Meiotic Recombinase) Deficient Plasmodium berghei Parasites
Mlambo, G., Coppens, I. & Kumar, N., Dec 21 2012, In: PloS one. 7, 12, e52480.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
2011
A proteogenomic analysis of Anopheles gambiae using high-resolution Fourier transform mass spectrometry
Chaerkady, R., Kelkar, D. S., Muthusamy, B., Kandasamy, K., Dwivedi, S. B., Sahasrabuddhe, N. A., Kim, M. S., Renuse, S., Pinto, S. M., Sharma, R., Pawar, H., Sekhar, N. R., Mohanty, A. K., Getnet, D., Yang, Y., Zhong, J., Dash, A. P., MacCallum, R. M., Delanghe, B., Mlambo, G., & 5 others, Nov 2011, In: Genome research. 21, 11, p. 1872-1881 10 p.Research output: Contribution to journal › Article › peer-review
Open Access46 Scopus citations -
2010
Functional immunogenicity of baculovirus expressing Pfs25, a human malaria transmission-blocking vaccine candidate antigen
Mlambo, G., Kumar, N. & Yoshida, S., Oct 8 2010, In: Vaccine. 28, 43, p. 7025-7029 5 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
2008
Critical role of a K+ channel in Plasmodium berghei transmission revealed by targeted gene disruption
Ellekvist, P., Maciel, J., Mlambo, G., Ricke, C. H., Colding, H., Klaerke, D. A. & Kumar, N., Apr 29 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 17, p. 6398-6402 5 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Murine model for assessment of Plasmodium falciparum transmission-blocking vaccine using transgenic Plasmodium berghei parasites expressing the target antigen Pfs25
Mlambo, G., Maciel, J. & Kumar, N., May 2008, In: Infection and immunity. 76, 5, p. 2018-2024 7 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Short report: A filter paper method for the detection of Plasmodium falciparum gametocytes by reverse transcription-polymerase chain reaction
Mlambo, G., Vasquez, Y., LeBlanc, R., Sullivan, D. & Kumar, N., Jan 2008, In: American Journal of Tropical Medicine and Hygiene. 78, 1, p. 114-116 3 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Transgenic rodent Plasmodium berghei parasites as tools for assessment of functional immunogenicity and optimization of human malaria vaccines
Mlambo, G. & Kumar, N., Nov 2008, In: Eukaryotic Cell. 7, 11, p. 1875-1879 5 p.Research output: Contribution to journal › Short survey › peer-review
Open Access11 Scopus citations -
2007
A modified Plasmodium falciparum growth inhibition assay (GIA) to assess activity of plasma from malaria endemic areas
Mlambo, G. & Kumar, N., Feb 2007, In: Experimental Parasitology. 115, 2, p. 211-214 4 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Analysis of genetic polymorphism in select vaccine candidate antigens and microsatellite loci in Plasmodium falciparum from endemic areas at varying altitudes
Mlambo, G., Sullivan, D., Mutambu, S. L., Soko, W., Mbedzi, J., Chivenga, J., Jaenisch, T., Gemperli, A. & Kumar, N., Jun 2007, In: Acta Tropica. 102, 3, p. 201-205 5 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
High prevalence of molecular markers for resistance to chloroquine and pyrimethamine in Plasmodium falciparum from Zimbabwe
Mlambo, G., Sullivan, D., Mutambu, S. L., Soko, W., Mbedzi, J., Chivenga, J., Gemperli, A. & Kumar, N., Sep 2007, In: Parasitology Research. 101, 4, p. 1147-1151 5 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
2006
Antibody responses to Plasmodium falciparum vaccine candidate antigens in three areas distinct with respect to altitude
Mlambo, G., Mutambu, S. L., Mduluza, T., Soko, W., Mbedzi, J., Chivenga, J., Lanar, D. E., Singh, S., Carucci, D., Gemperli, A. & Kumar, N., Nov 2006, In: Acta Tropica. 100, 1-2, p. 70-78 9 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
2003
Rifampicin and dexamethasone have similar effects on macrophage phagocytosis of zymosan, but differ in their effects on nitrite and TNF-α production
Mlambo, G. & Sigola, L. B., Apr 2003, In: International immunopharmacology. 3, 4, p. 513-522 10 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations