Giulio Agnetti

Assistant Professor

20052017
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Research Output 2005 2017

2017

Desmin loss and mitochondrial damage precede left ventricular systolic failure in volume overload heart failure

Guichard, J. L., Rogowski, M., Agnetti, G., Fu, L., Powell, P., Wei, C. C., Collawn, J. & Dell’Italia, L. J., 2017, In : American Journal of Physiology - Heart and Circulatory Physiology. 313, 1, p. H32-H45

Research output: Contribution to journalArticle

Desmin
Heart Failure
Fistula
Cardiac Myocytes
Mitochondrial Degradation
2016

Models of Heart Failure Based on the Cardiotoxicity of Anticancer Drugs

Mercurio, V., Pirozzi, F., Lazzarini, E., Marone, G., Rizzo, P., Agnetti, G., Tocchetti, C. G., Ghigo, A. & Ameri, P., Jun 1 2016, In : Journal of Cardiac Failure. 22, 6, p. 449-458 10 p.

Research output: Contribution to journalReview article

Heart Failure
Pharmaceutical Preparations
Anthracyclines
Second Primary Neoplasms
Antineoplastic Agents
2015

Alternatives to transplantation in the treatment of heart failure: New diagnostic and therapeutic insights

Nicolini, F., Piepoli, M. F., Agnetti, G. & Siniscalchi, G., 2015, In : BioMed Research International. 2015, 278163

Research output: Contribution to journalEditorial

Heart-Assist Devices
Treatment Failure
Heart Failure
Transplantation
Hemodynamics

Cofilin-2 phosphorylation and sequestration in myocardial aggregates: Novel pathogenetic mechanisms for idiopathic dilated cardiomyopathy

Subramanian, K., Gianni, D., Balla, C., Assenza, G. E., Joshi, M., Semigran, M. J., Macgillivray, T. E., Van Eyk, J. E., Agnetti, G., Paolocci, N., Bamburg, J. R., Agrawal, P. B. & Del Monte, F., Mar 31 2015, In : Journal of the American College of Cardiology. 65, 12, p. 1199-1214 16 p.

Research output: Contribution to journalArticle

Cofilin 2
Dilated Cardiomyopathy
Phosphorylation
Actin Depolymerizing Factors
Nemaline Myopathies

New Insights in the Diagnosis and Treatment of Heart Failure

Agnetti, G., Piepoli, M. F., Siniscalchi, G. & Nicolini, F., 2015, In : BioMed Research International. 2015, 265260

Research output: Contribution to journalReview article

Treatment Failure
Heart Failure
Heart Transplantation
Therapeutics
Acute Coronary Syndrome
2014

Cardiac resynchronization sensitizes the sarcomere to calcium by reactivating GSK-3?

Kirk, J. A., Holewinski, R. J., Kooij, V., Agnetti, G., Tunin, R. S., Witayavanitkul, N., De Tombe, P. P., Gao, W. D., Van Eyk, J. & Kass, D. A., Jan 2 2014, In : Journal of Clinical Investigation. 124, 1, p. 129-139 11 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Cardiac Resynchronization Therapy
Sarcomeres
Calcium
Myofibrils

Desmin modifications associate with amyloid-like oligomers deposition in heart failure

Agnetti, G., Halperin, V. L., Kirk, J. A., Chakir, K., Guo, Y., Lund, L., Nicolini, F., Gherli, T., Guarnieri, C., Caldarera, C. M., Tomaselli, G. F., Kass, D. A. & Van Eyk, J. E., 2014, In : Cardiovascular Research. 102, 1, p. 24-34 11 p.

Research output: Contribution to journalArticle

Desmin
Amyloid
Heart Failure
Cardiac Resynchronization Therapy
Post Translational Protein Processing

Protein post-translational modifications and misfolding: New concepts in heart failure

del Monte, F. & Agnetti, G., 2014, In : Proteomics - Clinical Applications. 8, 7-8, p. 534-542 9 p.

Research output: Contribution to journalReview article

Post Translational Protein Processing
Heart Failure
Protein Folding
Proteins
Proteomics
2012

Dephosphorylation of cardiac proteins in vitro - a matter of phosphatase specificity

Husberg, C., Agnetti, G., Holewinski, R. J., Christensen, G. & Van Eyk, J. E., Apr 2012, In : Proteomics. 12, 7, p. 973-978 6 p.

Research output: Contribution to journalArticle

Phosphoric Monoester Hydrolases
Phosphorylation
Proteins
Proteome
Alkaline Phosphatase
2011

Divide and Conquer: The application of organelle proteomics to heart failure

Agnetti, G., Husberg, C. & Van Eyk, J. E., Feb 18 2011, In : Circulation Research. 108, 4, p. 512-526 15 p.

Research output: Contribution to journalArticle

Organelles
Proteomics
Heart Failure
Post Translational Protein Processing
Technology

Modified Troponin I as a candidate marker for chronic heart failure a top-down perspective

Agnetti, G., Oct 2011, In : Circulation: Cardiovascular Genetics. 4, 5, p. 579-580 2 p.

Research output: Contribution to journalReview article

Troponin I
Heart Failure
2010

Modulation of mitochondrial proteome and improved mitochondrial function by biventricular pacing of dyssynchronous failing hearts

Agnetti, G., Kaludercic, N., Kane, L. A., Elliott, S. T., Guo, Y., Chakir, K., Samantapudi, D., Paolocci, N., Tomaselli, G. F., Kass, D. A. & Van Eyk, J. E., Feb 2010, In : Circulation: Cardiovascular Genetics. 3, 1, p. 78-87 10 p.

Research output: Contribution to journalArticle

Cardiac Resynchronization Therapy
Proteome
Mitochondria
Heart Failure
Adenosine Triphosphate
2009

American heart association scientific sessions 2009, november 14-18: Oral abstracts and posters

Anantharam, B., Bjørnstad, J., Agnetti, G., Chahal, N., Husberg, C., Louch, W. & Reilly, S., Dec 2009, In : Circulation. 120, 24

Research output: Contribution to journalArticle

American Heart Association
Posters
2008

Proteomic profiling of endothelin-1-stimulated hypertrophic cardiomyocytes reveals the increase of four different desmin species and α-B-crystallin

Agnetti, G., Bezstarosti, K., Dekkers, D. H. W., Verhoeven, A. J. M., Giordano, E., Guarnieri, C., Caldarera, C. M., Van Eyk, J. E. & Lamers, J. M. J., Jul 2008, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1784, 7-8, p. 1068-1076 9 p.

Research output: Contribution to journalArticle

alpha-Crystallin B Chain
Desmin
Endothelin-1
Cardiac Myocytes
Proteomics
2007

Proteomic technologies in the study of kinases: Novel tools for the investigation of PKC in the heart

Agnetti, G., Kane, L. A., Guarnieri, C., Caldarera, C. M. & Van Eyk, J. E., Jun 2007, In : Pharmacological Research. 55, 6, p. 511-522 12 p.

Research output: Contribution to journalArticle

Proteomics
Phosphotransferases
Technology
Post Translational Protein Processing
Proteins
2006

Optimization of paper bridge loading for 2-DE analysis in the basic pH region: Application to the mitochondrial subproteome

Kane, L. A., Yung, C. K., Agnetti, G., Neverova, I. & Van Eyk, J. E., Nov 2006, In : Proteomics. 6, 21, p. 5683-5687 5 p.

Research output: Contribution to journalArticle

Proteins
Gels
Mitochondria
Proton-Motive Force

Recent developments in proteomics: Implications for the study of cardiac hypertrophy and failure

Faber, M. J., Agnetti, G., Bezstarosti, K., Lankhuizen, I. M., Dalinghaus, M., Guarnieri, C., Caldarera, C. M., Helbing, W. A. & Lamers, J. M. J., Feb 2006, In : Cell Biochemistry and Biophysics. 44, 1, p. 11-29 19 p.

Research output: Contribution to journalReview article

Cardiomegaly
Proteomics
Heart Failure
Proteins
Rats
2005

Activation of glucose transport during simulated ischemia in H9c2 cardiac myoblasts is mediated by protein kinase C isoforms

Agnetti, G., Maraldi, T., Fiorentini, D., Giordano, E., Prata, C., Hakim, G., Muscari, C., Guarnieri, C. & Caldarera, C. M., Dec 5 2005, In : Life Sciences. 78, 3, p. 264-270 7 p.

Research output: Contribution to journalArticle

Cardiac Myoblasts
Protein Kinase C
Protein Isoforms
Ischemia
Chemical activation

Green tea modulation of inducible nitric oxide synthase in hypoxic/reoxygenated cardiomyocytes

Agnetti, G., Bordoni, A., Angeloni, C., Leoncini, E., Guarnieri, C., Caldarera, C. M., Biagi, P. L. & Hrelia, S., May 2005, In : Biochimie. 87, 5, p. 457-460 4 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type II
Tea
Cardiac Myocytes
Modulation
Dietary supplements