George Umanah

Assistant Professor

20082019
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Fingerprint Dive into the research topics where George Umanah is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
AMPA Receptors Medicine & Life Sciences
G-Protein-Coupled Receptors Chemical Compounds
Synucleins Medicine & Life Sciences
Mutation Medicine & Life Sciences
Fungal Proteins Medicine & Life Sciences
Dihydroxyphenylalanine Medicine & Life Sciences
Dopaminergic Neurons Medicine & Life Sciences
Ligands Medicine & Life Sciences

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Research Output 2008 2019

An IQSEC2 mutation associated with intellectual disability and autism results in decreased surface AMPA receptors

Rogers, E. J., Jada, R., Schragenheim-Rozales, K., Sah, M., Cortes, M., Florence, M., Levy, N. S., Moss, R., Walikonis, R. S., Palty, R., Shalgi, R., Lichtman, D., Kavushansky, A., Gerges, N. Z., Kahn, I., Umanah, G. & Levy, A. P., Feb 12 2019, In : Frontiers in Molecular Neuroscience. 12, 43.

Research output: Contribution to journalArticle

Open Access
AMPA Receptors
Autistic Disorder
Intellectual Disability
Mutation
Clustered Regularly Interspaced Short Palindromic Repeats

IQSEC2-Associated Intellectual Disability and Autism

Levy, N. S., Umanah, G., Rogers, E. J., Jada, R., Lache, O. & Levy, A. P., Jun 21 2019, In : International journal of molecular sciences. 20, 12

Research output: Contribution to journalReview article

Open Access
disabilities
AMPA Receptors
Autistic Disorder
Calmodulin
Intellectual Disability

A homozygous ATAD1 mutation impairs postsynaptic AMPA receptor trafficking and causes a lethal encephalopathy

Piard, J., Umanah, G., Harms, F. L., Abalde-Atristain, L., Amram, D., Chang, M., Chen, R., Alawi, M., Salpietro, V., Rees, M. I., Chung, S. K., Houlden, H., Verloes, A., Dawson, T. M., Dawson, V., Van Maldergem, L. & Kutsche, K., Mar 1 2018, In : Brain. 141, 3, p. 651-661 11 p.

Research output: Contribution to journalArticle

AMPA Receptors
Brain Diseases
Mutation
Adenosine Triphosphatases
Arthrogryposis

GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers

Kim, S., Yun, S. P., Lee, S., Umanah, G., Bandaru, V. V. R., Yin, X., Rhee, P., Karuppagounder, S., Kwon, S. H., Lee, H., Mao, X., Kim, D., Pandey, A., Lee, G., Dawson, V., Dawson, T. M. & Ko, H. S., Jan 23 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 4, p. 798-803 6 p.

Research output: Contribution to journalArticle

Synucleins
Glucosylceramidase
Gaucher Disease
Glycosphingolipids
Dopaminergic Neurons

Poly(ADP-ribose) drives pathologic a-synuclein neurodegeneration in Parkinson’s disease

Kam, T. I., Mao, X., Park, H., Chou, S. C., Karuppagounder, S., Umanah, G., Yun, S. P., Brahmachari, S., Panicker, N., Chen, R., Andrabi, S. A., Qi, C., Poirier, G. G., Pletnikova, O., Troncoso, J. C., Bekris, L. M., Leverenz, J. B., Pantelyat, A., Ko, H. S., Rosenthal, L. I. S. & 2 others, Dawson, T. M. & Dawson, V., Nov 2 2018, In : Science. 362, 6414, eaat8407.

Research output: Contribution to journalArticle

Synucleins
Poly Adenosine Diphosphate Ribose
Parkinson Disease
Adenosine
Poisons