George Capone

Research output

Research output per year 1979 2004 2009 2011 2015 2018 2020 2021 2023 2023

• 61 Article
• 11 Review article
• 3 Chapter
• 3 Comment/debate

Research output per year

Research output per year

Search results

• 2023

  Cardiometabolic risk in young adults with Down syndrome

  Manfredo, J., Capone, G., Yanek, L., McCarter, R., Zemel, B., Kelly, A. & Magge, S. N., Jul 2023, In: American Journal of Medical Genetics, Part A. 191, 7, p. 1758-1768 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Down Syndrome 100%
  • Young Adult 77%
  • Nutrition Surveys 70%
  • Blood Pressure 12%
  • Triglycerides 10%

• Cardiovascular Complications of Down Syndrome: Scoping Review and Expert Consensus

  Dimopoulos, K., Constantine, A., Clift, P., Condliffe, R., Moledina, S., Jansen, K., Inuzuka, R., Veldtman, G. R., Cua, C. L., Tay, E. L. W., Opotowsky, A. R., Giannakoulas, G., Alonso-Gonzalez, R., Cordina, R., Capone, G., Namuyonga, J., Scott, C. H., D'Alto, M., Gamero, F. J., Chicoine, B., & 6 othersGu, H., Limsuwan, A., Majekodunmi, T., Budts, W., Coghlan, G. & Broberg, C. S., Jan 31 2023, In: Circulation. 147, 5, p. 425-441 17 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Down Syndrome 100%
  • Heart Diseases 25%
  • Cardiovascular Diseases 23%
  • Endocrine System Diseases 21%
  • Geography 20%

• Children with Down syndrome who experience developmental skill loss, characterization, and phenomenology: A case series

  Bernad-Ripoll, S., O'Neill, M. & Capone, G. T., Dec 2023, In: American Journal of Medical Genetics, Part C: Seminars in Medical Genetics. 193, 4, e32077.

  Research output: Contribution to journal › Article › peer-review

  • Down Syndrome 100%
  • Autistic Disorder 63%
  • Communication 48%
  • Child 41%
  • Population Biological Variation 39%

• Immunotherapy responsiveness and risk of relapse in Down syndrome regression disorder

  Santoro, J. D., Spinazzi, N. A., Filipink, R. A., Hayati-Rezvan, P., Kammeyer, R., Patel, L., Sannar, E. A., Dwyer, L., Banerjee, A. K., Khoshnood, M., Jafarpour, S., Boyd, N. K., Partridge, R., Gombolay, G. Y., Christy, A. L., Real de Asua, D., del Carmen Ortega, M., Manning, M. A., Van Mater, H., Worley, G., & 6 othersFranklin, C., Stanley, M. A., Brown, R., Capone, G. T., Quinn, E. A. & Rafii, M. S., Dec 2023, In: Translational psychiatry. 13, 1, 276.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Down Syndrome 100%
  • Immunotherapy 84%
  • Recurrence 55%
  • Catatonia 46%
  • Autoimmunity 31%

• Psychopharmacological treatments in Down syndrome and autism spectrum disorder: State of the research and practical considerations

  Baumer, N. T. & Capone, G., Dec 2023, In: American Journal of Medical Genetics, Part C: Seminars in Medical Genetics. 193, 4, e32069.

  Research output: Contribution to journal › Review article › peer-review

  • Down Syndrome 100%
  • Autism Spectrum Disorder 99%
  • Therapeutics 15%
  • Pharmacology 12%
  • Behavioral Symptoms 11%
• 2022

  Assessment and Diagnosis of Down Syndrome Regression Disorder: International Expert Consensus

  Santoro, J. D., Patel, L., Kammeyer, R., Filipink, R. A., Gombolay, G. Y., Cardinale, K. M., Real de Asua, D., Zaman, S., Santoro, S. L., Marzouk, S. M., Khoshnood, M., Vogel, B. N., Tanna, R., Pagarkar, D., Dhanani, S., Ortega, M. D. C., Partridge, R., Stanley, M. A., Sanders, J. S., Christy, A., & 11 othersSannar, E. M., Brown, R., McCormick, A. A., Van Mater, H., Franklin, C., Worley, G., Quinn, E. A., Capone, G. T., Chicoine, B., Skotko, B. G. & Rafii, M. S., Jul 15 2022, In: Frontiers in Neurology. 13, 940175.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Down Syndrome 100%
  • Terminology 55%
  • Spinal Puncture 16%
  • Neuroimaging 12%
  • Datasets 10%

• Conducting clinical trials in persons with Down syndrome: summary from the NIH INCLUDE Down syndrome clinical trials readiness working group

  Baumer, N. T., Becker, M. L., Capone, G. T., Egan, K., Fortea, J., Handen, B. L., Head, E., Hendrix, J. E., Litovsky, R. Y., Strydom, A., Tapia, I. E. & Rafii, M. S., Dec 2022, In: Journal of Neurodevelopmental Disorders. 14, 1, 22.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Down Syndrome 100%
  • National Institutes of Health (U.S.) 99%
  • Clinical Trials 62%
  • Longevity 34%
  • Education 24%
• 2021

  Author Correction: Identifying genetic factors that contribute to the increased risk of congenital heart defects in infants with Down syndrome (Scientific Reports, (2020), 10, 1, (18051), 10.1038/s41598-020-74650-4)

  Trevino, C. E., Holleman, A. M., Corbitt, H., Maslen, C. L., Rosser, T. C., Cutler, D. J., Johnston, H. R., Rambo-Martin, B. L., Oberoi, J., Dooley, K. J., Capone, G. T., Reeves, R. H., Cordell, H. J., Keavney, B. D., Agopian, A. J., Goldmuntz, E., Gruber, P. J., O’Brien, J. E., Bittel, D. C., Wadhwa, L., & 6 othersCua, C. L., Moskowitz, I. P., Mulle, J. G., Epstein, M. P., Sherman, S. L. & Zwick, M. E., Dec 2021, In: Scientific reports. 11, 1, 15164.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Congenital Heart Defects 100%
  • Down Syndrome 89%

• Capturing cognitive and behavioral variability among individuals with Down syndrome: a latent profile analysis

  The Down Syndrome Cognition Project, Dec 2021, In: Journal of Neurodevelopmental Disorders. 13, 1, 16.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Down Syndrome 100%
  • Cognition 75%
  • Psychological Adaptation 73%
  • Autistic Disorder 47%
  • Behavioral Genetics 22%

• Co-occurring medical conditions in aging adults with Down syndrome

  Capone, G. & Chicoine, B., Jan 1 2021, The Neurobiology of Aging and Alzheimer Disease in Down Syndrome. Elsevier, p. 209-231 23 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Down Syndrome 100%
  • Spondylosis 65%
  • Neural Tube 59%
  • Psychological Adaptation 55%
  • Knee Osteoarthritis 52%

• Cross-sectional exploration of plasma biomarkers of alzheimer’s disease in down syndrome: Early data from the longitudinal investigation for enhancing down syndrome research (life-dsr) study

  Hendrix, J. A., Airey, D. C., Britton, A., Burke, A. D., Capone, G. T., Chavez, R., Chen, J., Chicoine, B., Costa, A. C. S., Dage, J. L., Doran, E., Esbensen, A., Evans, C. L., Faber, K. M., Foroud, T. M., Hart, S., Haugen, K., Head, E., Hendrix, S., Hillerstrom, H., & 26 othersKishnani, P. S., Krell, K., Ledesma, D. L., Lai, F., Lott, I., Ochoa-Lubinoff, C., Mason, J., Nicodemus-Johnson, J., Proctor, N. K., Pulsifer, M. B., Revta, C., Rosas, H. D., Rosser, T. C., Santoro, S., Schafer, K., Scheidemantel, T., Schmitt, F., Skotko, B. G., Stasko, M. R., Talboy, A., Torres, A., Wilmes, K., Woodward, J., Zimmer, J. A., Feldman, H. H. & Mobley, W., May 1 2021, In: Journal of Clinical Medicine. 10, 9, 1907.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Down Syndrome 100%
  • Alzheimer Disease 74%
  • Biomarkers 62%
  • tau Proteins 17%
  • Glial Fibrillary Acidic Protein 15%

• Pneumonia and respiratory infections in Down syndrome: A scoping review of the literature

  Santoro, S. L., Chicoine, B., Jasien, J. M., Kim, J. L., Stephens, M., Bulova, P. & Capone, G., Jan 2021, In: American Journal of Medical Genetics, Part A. 185, 1, p. 286-299 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Down Syndrome 100%
  • Respiratory Tract Infections 89%
  • Pneumonia 77%
  • National Library of Medicine (U.S.) 26%
  • Pandemics 20%
  4 Scopus citations
• 2020

  Co-occurring medical conditions in adults with Down syndrome: A systematic review toward the development of health care guidelines. Part II

  Capone, G., Stephens, M., Santoro, S., Chicoine, B., Bulova, P., Peterson, M., Jasien, J. & Smith, A. J., Jul 1 2020, In: American Journal of Medical Genetics, Part A. 182, 7, p. 1832-1845 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Down Syndrome 100%
  • Systematic Reviews 70%
  • Guidelines 61%
  • Delivery of Health Care 58%
  • Hip Dislocation 39%
  3 Scopus citations

• Current research approaches to down syndrome: Translational research perspectives

  Capone, G. T., 2020, In: American journal on intellectual and developmental disabilities. 25, 2, p. 93-96 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Translational Research 100%
  • Down Syndrome 83%
  • Translational Medical Research 69%
  • research approach 58%
  • Biomedical Research 21%

• Gynecologic Care in Women With Down Syndrome: Findings From a National Registry

  Smith, A. J. B., Applebaum, J., Tanner, E. J. & Capone, G. T., Sep 1 2020, In: Obstetrics and gynecology. 136, 3, p. 518-523 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Down Syndrome 100%
  • Registries 76%
  • Papanicolaou Test 22%
  • Early Detection of Cancer 18%
  • CI 22 14%

• Identifying genetic factors that contribute to the increased risk of congenital heart defects in infants with Down syndrome

  Trevino, C. E., Holleman, A. M., Corbitt, H., Maslen, C. L., Rosser, T. C., Cutler, D. J., Johnston, H. R., Rambo-Martin, B. L., Oberoi, J., Dooley, K. J., Capone, G. T., Reeves, R. H., Cordell, H. J., Keavney, B. D., Agopian, A. J., Goldmuntz, E., Gruber, P. J., O’Brien, J. E., Bittel, D. C., Wadhwa, L., & 5 othersCua, C. L., Mulle, J. G., Epstein, M. P., Sherman, S. L. & Zwick, M. E., Dec 1 2020, In: Scientific reports. 10, 1, 18051.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Atrioventricular Septal Defect 100%
  • Congenital Heart Defects 79%
  • Down Syndrome 70%
  • Whole Exome Sequencing 8%
  • Whole Genome Sequencing 8%
  1 Scopus citations

• Medical Care of Adults with down Syndrome: A Clinical Guideline

  Tsou, A. Y., Bulova, P., Capone, G., Chicoine, B., Gelaro, B., Harville, T. O., Martin, B. A., McGuire, D. E., McKelvey, K. D., Peterson, M., Tyler, C., Wells, M. & Whitten, M. S., Oct 20 2020, In: JAMA - Journal of the American Medical Association. 324, 15, p. 1543-1556 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Down Syndrome 100%
  • Guidelines 61%
  • Osteoporosis 18%
  • Cardiovascular Diseases 15%
  • Obesity 14%
  4 Scopus citations

• Opportunities, barriers, and recommendations in down syndrome research

  Hendrix, J. A., Amon, A., Abbeduto, L., Agiovlasitis, S., Alsaied, T., Anderson, H. A., Bain, L. J., Baumer, N., Bhattacharyya, A., Bogunovic, D., Botteron, K. N., Capone, G., Chandan, P., Chase, I., Chicoine, B., Cieuta-Walti, C., Deruisseau, L. R., Durand, S., Esbensen, A., Fortea, J., & 32 othersGiménez, S., Granholm, A. C., Mattie, L. J., Head, E., Hillerstrom, H., Jacola, L. M., Janicki, M. P., Jasien, J. M., Kamer, A. R., Kent, R. D., Khor, B., Lawrence, J. B., Lemonnier, C., Lewanda, A. F., Mobley, W., Moore, P. E., Nelson, L. P., Oreskovic, N. M., Osorio, R. S., Patterson, D., Rasmussen, S. A., Reeves, R. H., Roizen, N., Santoro, S., Sherman, S. L., Talib, N., Tapia, I. E., Walsh, K. M., Warren, S. F., White, A. N., Wong, G. W. & Yi, J. S., 2020, In: Translational Science of Rare Diseases. 5, 3-4, p. 99-129 31 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Down Syndrome 100%
  • Quality of Life 10%
  • Life Expectancy 7%
  • Research Design 6%
  • Health 3%

• Unexplained regression in Down syndrome: 35 cases from an international Down syndrome database

  Santoro, S. L., Cannon, S., Capone, G., Franklin, C., Hart, S. J., Hobensack, V., Kishnani, P. S., Macklin, E. A., Manickam, K., McCormick, A., Nash, P., Oreskovic, N. M., Patsiogiannis, V., Steingass, K., Torres, A., Valentini, D., Vellody, K. & Skotko, B. G., Apr 1 2020, In: Genetics in Medicine. 22, 4, p. 767-776 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Down Syndrome 100%
  • Databases 57%
  • Matched-Pair Analysis 25%
  • Iodide Peroxidase 24%
  • Autism Spectrum Disorder 19%
  2 Scopus citations
• 2019

  Characteristics Associated with Autism Spectrum Disorder Risk in Individuals with Down Syndrome

  The Down Syndrome Cognition Project, Sep 15 2019, In: Journal of Autism and Developmental Disorders. 49, 9, p. 3543-3556 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Down Syndrome 100%
  • Autism Spectrum Disorder 85%
  • autism 79%
  • Psychological Adaptation 37%
  • Group 9%
  10 Scopus citations
• 2018

  Analysis of copy number variants on chromosome 21 in down syndrome-associated congenital heart defects

  Rambo-Martin, B. L., Mulle, J. G., Cutler, D. J., Bean, L. J. H., Rosser, T. C., Dooley, K. J., Cua, C., Capone, G., Maslen, C. L., Reeves, R. H., Sherman, S. L. & Zwick, M. E., Jan 1 2018, In: G3: Genes, Genomes, Genetics. 8, 1, p. 105-111 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Atrioventricular Septal Defect 100%
  • Chromosomes, Human, Pair 21 88%
  • Congenital Heart Defects 79%
  • Down Syndrome 70%
  • African Americans 12%
  9 Scopus citations

• Associations between medical history, cognition, and behavior in youth with down syndrome: A report from the down syndrome cognition project

  Rosser, T. C., Edgin, J. O., Capone, G. T., Hamilton, D. R., Allen, E. G., Dooley, K. J., Anand, P., Strang, J. F., Armour, A. C., Frank-Crawford, M. A., Channell, M. M., Pierpont, E. I., Feingold, E., Maslen, C. L., Reeves, R. H. & Sherman, S. L., Nov 2018, In: American journal on intellectual and developmental disabilities. 123, 6, p. 514-528 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Down Syndrome 100%
  • Cognition 75%
  • Congenital Heart Defects 56%
  • Social Class 45%
  • Medical Records 39%
  10 Scopus citations

• Comparison of Aberrant Behavior Checklist profiles across Prader–Willi syndrome, Down syndrome, and autism spectrum disorder

  Salehi, P., Herzig, L., Capone, G., Lu, A., Oron, A. P. & Kim, S. J., Dec 2018, In: American Journal of Medical Genetics, Part A. 176, 12, p. 2751-2759 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Down Syndrome 100%
  • Autism Spectrum Disorder 99%
  • Checklist 93%
  • Genetic Databases 21%
  • Neurodevelopmental Disorders 9%
  6 Scopus citations

• Co-occurring medical conditions in adults with Down syndrome: A systematic review toward the development of health care guidelines

  for the Down Syndrome Medical Interest Group DSMIG-USA Adult Health Care Workgroup, Jan 2018, In: American Journal of Medical Genetics, Part A. 176, 1, p. 116-133 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Down Syndrome 100%
  • Systematic Reviews 70%
  • National Library of Medicine (U.S.) 67%
  • Guidelines 61%
  • Delivery of Health Care 58%
  39 Scopus citations

• Intellectual Disability and Psychotropic Medications

  Herzig, L., de Lacy, N., Capone, G. & Radesky, J., Sep 1 2018, In: Journal of developmental and behavioral pediatrics : JDBP. 39, 7, p. 591-593 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Self-Injurious Behavior 100%
  • intellectual disability 81%
  • Intellectual Disability 76%
  • medication 69%
  • father 63%

• Regression in adolescents and adults with down syndrome

  Chicoine, B. & Capone, G., Oct 29 2018, Physical Health of Adults with Intellectual and Developmental Disabilities. Springer International Publishing, p. 121-140 20 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
• 2017

  Outcome measures for clinical trials in down syndrome

  Esbensen, A. J., Hooper, S. R., Fidler, D., Hartley, S. L., Edgin, J., D'Ardhuy, X. L., Capone, G., Conners, F. A., Mervis, C. B., Abbeduto, L., Rafii, M., Krinsky-Mchale, S. J., Urv, T., Dykens, E., Esbenson, A., Hartlay, S., Keller, S. & Weir, S., May 2017, In: American journal on intellectual and developmental disabilities. 122, 3, p. 247-281 35 p.

  Research output: Contribution to journal › Article › peer-review

  • Down Syndrome 100%
  • Clinical Trials 86%
  • Developmental Disabilities 54%
  • Intellectual Disability 50%
  • Health Care Outcome Assessment 47%
  33 Scopus citations

• The Arizona cognitive test battery for down syndrome: Test-retest reliability & practice effects

  Edgin, J. O., Anand, P., Rosser, T., Pierpont, E. I., Figueroa, C., Hamilton, D., Huddleston, L., Mason, G., Spaǹo, G., Toole, L., Nguyen-Driver, M., Capone, G., Abbeduto, L., Maslen, C., Reeves, R. H. & Sherman, S., May 2017, In: American journal on intellectual and developmental disabilities. 122, 3, p. 215-234 20 p.

  Research output: Contribution to journal › Article › peer-review

  • Test-retest Reliability 100%
  • Down Syndrome 87%
  • test battery 78%
  • Battery 73%
  • Psychological Practice 65%
  16 Scopus citations
• 2016

  Erratum to: Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models [Genome Biol. 16, (2015) 263]

  Mendioroz, M., Do, C., Jiang, X., Liu, C., Darbary, H. K., Lang, C. F., Lin, J., Thomas, A., Abu-Amero, S., Stanier, P., Temkin, A., Yale, A., Liu, M. M., Li, Y., Salas, M., Kerkel, K., Capone, G., Silverman, W. P., Yu, Y. E., Moore, G., & 2 othersWegiel, J. & Tycko, B., Jun 9 2016, In: Genome biology. 17, 1, 123.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Guanfacine Use in Children with Down Syndrome and Comorbid Attention-Deficit Hyperactivity Disorder (ADHD) with Disruptive Behaviors

  Capone, G. T., Brecher, L. & Bay, M., Jul 1 2016, In: Journal of Child Neurology. 31, 8, p. 957-964 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Guanfacine 100%
  • Down Syndrome 66%
  • Attention Deficit Disorder with Hyperactivity 64%
  • Checklist 41%
  • Child 27%
  7 Scopus citations

• Safety and efficacy of rivastigmine in children with Down syndrome: A double blind placebo controlled trial

  Spiridigliozzi, G. A., Hart, S. J., Heller, J. H., Schneider, H. E., Baker, J. A., Weadon, C., Capone, G. T. & Kishnani, P. S., Jun 1 2016, In: American Journal of Medical Genetics, Part A. 170, 6, p. 1545-1555 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Rivastigmine 100%
  • Down Syndrome 70%
  • Placebos 47%
  • Safety 39%
  • Child 29%
  8 Scopus citations
• 2015

  Contribution of copy-number variation to Down syndrome-associated atrioventricular septal defects

  Ramachandran, D., Mulle, J. G., Locke, A. E., Bean, L. J. H., Rosser, T. C., Bose, P., Dooley, K. J., Cua, C. L., Capone, G. T., Reeves, R. H., Maslen, C. L., Cutler, D. J., Sherman, S. L. & Zwick, M. E., Jul 2 2015, In: Genetics in Medicine. 17, 7, p. 554-560 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Atrioventricular Septal Defect 100%
  • Down Syndrome 70%
  • Complete atrioventricular septal defect 21%
  • Viverridae 19%
  • Heart 17%
  18 Scopus citations

• Executive functions among youth with Down Syndrome and co-existing neurobehavioural disorders

  Pritchard, A. E., Kalback, S., Mccurdy, M. & Capone, G. T., Dec 1 2015, In: Journal of Intellectual Disability Research. 59, 12, p. 1130-1141 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Executive Function 100%
  • Down Syndrome 98%
  • Rating 32%
  • Metacognition 21%
  • Equipment and Supplies 17%
  14 Scopus citations

• Genome-wide association study of down syndrome-associated atrioventricular septal defects

  Ramachandran, D., Zeng, Z., Locke, A. E., Mulle, J. G., Bean, L. J. H., Rosser, T. C., Dooley, K. J., Cua, C. L., Capone, G. T., Reeves, R. H., Maslen, C. L., Cutler, D. J., Feingold, E., Sherman, S. L. & Zwick, M. E., 2015, In: G3: Genes, Genomes, Genetics. 5, 10, p. 1961-1971 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Atrioventricular Septal Defect 100%
  • Genome-Wide Association Study 71%
  • Down Syndrome 70%
  • Complete atrioventricular septal defect 26%
  • Chromosomes, Human, Pair 21 22%
  19 Scopus citations

• Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models

  Mendioroz, M., Do, C., Jiang, X., Liu, C., Darbary, H. K., Lang, C. F., Lin, J., Thomas, A., Abu-Amero, S., Stanier, P., Temkin, A., Yale, A., Liu, M. M., Li, Y., Salas, M., Kerkel, K., Capone, G., Silverman, W., Yu, Y. E., Moore, G., & 2 othersWegiel, J. & Tycko, B., Nov 25 2015, In: Genome biology. 16, 1, 263.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Down syndrome 100%
  • methylation 81%
  • aneuploidy 77%
  • Aneuploidy 73%
  • DNA methylation 72%
  44 Scopus citations
• 2013

  Adolescents and young adults with down syndrome presenting to a medical clinic with depression: Co-morbid obstructive sleep apnea

  Capone, G. T., Aidikoff, J. M., Taylor, K. & Rykiel, N., Sep 2013, In: American Journal of Medical Genetics, Part A. 161, 9, p. 2188-2196 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Down Syndrome 100%
  • Obstructive Sleep Apnea 98%
  • Young Adult 77%
  • Mood Disorders 37%
  • Dual (Psychiatry) Diagnosis 27%
  31 Scopus citations

• Down syndrome: Genes, model systems, and progress towards pharmacotherapies and clinical trials for cognitive deficits

  Busciglio, J., Capone, G., O'Byran, J. P. & Gardiner, K. J., 2013, In: Cytogenetic and Genome Research. 141, 4, p. 260-271 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Down Syndrome 100%
  • Clinical Trials 62%
  • Drug Therapy 56%
  • Genes 38%
  • Intellectual Disability 36%
  13 Scopus citations
• 2012

  A case-control comparison of lingual tonsillar size in children with and without down syndrome

  Sedaghat, A. R., Flax-Goldenberg, R. B., Gayler, B. W., Capone, G. T. & Ishman, S. L., May 1 2012, In: Laryngoscope. 122, 5, p. 1165-1169 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Down Syndrome 100%
  • Tongue 89%
  • Palatine Tonsil 49%
  • Child 41%
  • Spine 32%
  24 Scopus citations

• The role of hope in adaptation to uncertainty: The experience of caregivers of children with Down syndrome

  Truitt, M., Biesecker, B., Capone, G., Bailey, T. & Erby, L., May 2012, In: Patient Education and Counseling. 87, 2, p. 233-238 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Hope 100%
  • Down Syndrome 90%
  • Uncertainty 80%
  • Caregivers 74%
  • Child 37%
  41 Scopus citations
• 2011

  Adolescents and Young Adults With Down Syndrome Presenting to a Medical Clinic With Depression: Phenomenology and Characterization Using the Reiss Scales and Aberrant Behavior Checklist

  Capone, G. T., Aidikoff, J. M. & Goyal, P., Oct 2011, In: Journal of Mental Health Research in Intellectual Disabilities. 4, 4, p. 244-264 21 p.

  Research output: Contribution to journal › Article › peer-review

  • Dual (Psychiatry) Diagnosis 100%
  • Down Syndrome 97%
  • Checklist 91%
  • Young Adult 75%
  • Psychopathology 69%
  5 Scopus citations

• Autism spectrum disorder in Down syndrome: Cluster analysis of Aberrant Behaviour Checklist data supports diagnosis

  Ji, N. Y., Capone, G. T. & Kaufmann, W. E., Nov 2011, In: Journal of Intellectual Disability Research. 55, 11, p. 1064-1077 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Autism Spectrum Disorders 100%
  • Cluster Analysis 93%
  • Down Syndrome 93%
  • Autism Spectrum Disorder 70%
  • Checklist 66%
  37 Scopus citations

• Down syndrome: National conference on patient registries, research databases, and biobanks

  Oster-Granite, M. L., Parisi, M. A., Abbeduto, L., Berlin, D. S., Bodine, C., Bynum, D., Capone, G., Collier, E., Hall, D., Kaeser, L., Kaufmann, P., Krischer, J., Livingston, M., McCabe, L. L., Pace, J., Pfenninger, K., Rasmussen, S. A., Reeves, R. H., Rubinstein, Y., Sherman, S., & 5 othersTerry, S. F., SieWhitten, M., Williams, S., McCabe, E. R. B. & Maddox, Y. T., Sep 2011, In: Molecular genetics and metabolism. 104, 1-2, p. 13-22 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Kennedy Cyclization 100%
  • Down Syndrome 60%
  • Congresses 57%
  • Registries 46%
  • Industry 42%
  28 Scopus citations

• Pharmacotherapy for children with down syndrome

  Capone, G., Jan 1 2011, Neurocognitive Rehabilitation of Down Syndrome: The Early Years. Cambridge University Press, p. 96-116 21 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Down Syndrome 100%
  • intellectual disability 81%
  • Intellectual Disability 77%
  • Drug Therapy 48%
  • Child 35%
  4 Scopus citations
• 2010

  Development and validation of the Arizona Cognitive Test Battery for Down syndrome

  Edgin, J. O., Mason, G. M., Allman, M. J., Capone, G. T., DeLeon, I., Maslen, C., Reeves, R. H., Sherman, S. L. & Nadel, L., 2010, In: Journal of Neurodevelopmental Disorders. 2, 3, p. 149-164 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Down Syndrome 100%
  • Aptitude 18%
  • Benchmarking 14%
  • Genetic Variation 13%
  • Intellectual Disability 12%
  123 Scopus citations

• The emergence of pharmacotherapies for cognitive function in Down syndrome

  Capone, G. T., Dec 2010, In: American Journal of Medical Genetics, Part A. 152 A, 12, p. 3026-3027 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  3 Scopus citations

• Variation in folate pathway genes contributes to risk of congenital heart defects among individuals with Down syndrome

  Locke, A. E., Dooley, K. J., Tinker, S. W., Cheong, S. Y., Feingold, E., Allen, E. G., Freeman, S. B., Torfs, C. P., Cua, C. L., Epstein, M. P., Wu, M. C., Lin, X., Capone, G., Sherman, S. L. & Bean, L. J. H., Sep 2010, In: Genetic epidemiology. 34, 6, p. 613-623 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Atrioventricular Septal Defect 100%
  • Congenital Heart Defects 95%
  • Down Syndrome 84%
  • Folic Acid 80%
  • Single Nucleotide Polymorphism 57%
  56 Scopus citations
• 2009

  Obstructive sleep apnea in adults with Down syndrome

  Trois, M. S., Capone, G. T., Lutz, J. A., Melendres, M. C., Schwartz, A. R., Collop, N. A. & Marcus, C. L., Aug 15 2009, In: Journal of Clinical Sleep Medicine. 5, 4, p. 317-323 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Down Syndrome 100%
  • Obstructive Sleep Apnea 98%
  • Apnea 40%
  • Hypoventilation 12%
  • Morbidity 11%
  88 Scopus citations

• Postnatal diagnosis of Down syndrome: Synthesis of the evidence on how best to deliver the news

  Skotko, B. G., Capone, G. T. & Kishnani, P. S., 2009, In: Pediatrics. 124, 4, p. e751-e758

  Research output: Contribution to journal › Article › peer-review

  • Down Syndrome 100%
  • Parents 32%
  • Physicians 20%
  • Organizations 17%
  • Nonprofit Organizations 16%
  69 Scopus citations

• Prenatal diagnosis of down syndrome: How best to deliver the news

  Skotko, B. G., Kishnani, P. S. & Capone, G. T., Nov 2009, In: American Journal of Medical Genetics, Part A. 149, 11, p. 2361-2367 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Down Syndrome 100%
  • Prenatal Diagnosis 97%
  • Parents 54%
  • Physicians 45%
  • Organizations 40%
  59 Scopus citations

• The efficacy, safety, and tolerability of donepezil for the treatment of young adults with Down syndrome'

  Kishnani, P. S., Sommer, B. R., Handen, B. L., Seltzer, B., Capone, G. T., Spiridigliozzi, G. A., Heller, J. H., Richardson, S. & McRae, T., Aug 2009, In: American Journal of Medical Genetics, Part A. 149, 8, p. 1641-1654 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Donepezil 100%
  • Down Syndrome 76%
  • Young Adult 59%
  • Safety 43%
  • Placebos 25%
  40 Scopus citations