Research Output 1995 2018

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2018

Exposure– and Dose–response Analyses in Dose Selection and Labeling of FDA-approved Biologics

Ogasawara, K., Breder, C. D., Lin, D. H. & Alexander, G. C. Jan 1 2018 In : Clinical Therapeutics. 40, 1, p. 95-102.e2

Research output: Research - peer-reviewArticle

United States Food and Drug Administration
Biological Products
Pharmaceutical Preparations
Drug Evaluation
Licensure
2017

Association between direct-to-consumer advertising and testosterone testing and initiation in the United States, 2009-2013

Layton, J. B., Kim, Y., Alexander, G. C. & Emery, S. L. Mar 21 2017 In : JAMA - Journal of the American Medical Association. 317, 11, p. 1159-1166 8 p.

Research output: Research - peer-reviewArticle

Testosterone
Direct-to-Consumer Advertising
Serum
Southeastern United States
Insurance

Association between lithium use and risk of Alzheimer's disease

Cheng, C., Zandi, P., Stuart, E., Lin, C. H., Su, P. Y., Alexander, G. C. & Lan, T. H. Feb 1 2017 In : Journal of Clinical Psychiatry. 78, 2, p. e139-e145

Research output: Research - peer-reviewArticle

Lithium
Alzheimer Disease
National Health Programs
Bipolar Disorder
Dementia

Cardiovascular Risks of Exogenous Testosterone Use Among Men: A Systematic Review and Meta-Analysis

Alexander, G. C., Iyer, G., Lucas, E., Lin, D. & Singh, S. Mar 1 2017 In : American Journal of Medicine. 130, 3, p. 293-305 13 p.

Research output: Research - peer-reviewArticle

Testosterone
Meta-Analysis
Randomized Controlled Trials
Odds Ratio
Therapeutics

Evaluating the Impact of Prescription Fill Rates on Risk Stratification Model Performance

Chang, H. Y., Richards, T. M., Shermock, K. M., Dalpoas, S. E., Kan, H. J., Caleb Alexander, G., Weiner, J. P. & Kharrazi, H. Jan 1 2017 In : Medical Care. 55, 12, p. 1052-1060 9 p.

Research output: Research - peer-reviewArticle

Prescriptions
Costs and Cost Analysis
Risk Adjustment
Electronic Health Records
Medication Adherence

Impact of prescription drug monitoring programs (PDMPs) on opioid utilization among Medicare beneficiaries in 10 US States

Moyo, P., Simoni-Wastila, L., Griffin, B. A., Onukwugha, E., Harrington, D., Alexander, G. C. & Palumbo, F. 2017 (Accepted/In press) In : Addiction.

Research output: Research - peer-reviewArticle

Prescription Drugs
Drug Monitoring
Medicare
Opioid Analgesics
Prescriptions

Non-buprenorphine opioid utilization among patients using buprenorphine

Daubresse, M., Saloner, B., Pollack, H. A. & Alexander, G. C. 2017 (Accepted/In press) In : Addiction.

Research output: Research - peer-reviewArticle

Buprenorphine
Opioid Analgesics
Therapeutics
Prescriptions
Morphine

Patterns of Buprenorphine-Naloxone Treatment for Opioid Use Disorder in a Multistate Population

Saloner, B., Daubresse, M. & Caleb Alexander, G. Apr 13 2017 (Accepted/In press) In : Medical Care.

Research output: Research - peer-reviewArticle

Opioid Analgesics
Population
Therapeutics
Naloxone Drug Combination Buprenorphine
Logistic Models

Physician attitudes and experiences with Maryland's prescription drug monitoring program (PDMP)

Lin, D. H., Lucas, E., Murimi, I. B., Jackson, K., Baier, M., Frattaroli, S., Gielen, A. C., Moyo, P., Simoni-Wastila, L. & Alexander, G. C. Feb 1 2017 In : Addiction. 112, 2, p. 311-319 9 p.

Research output: Research - peer-reviewArticle

Prescription Drugs
Drug Monitoring
Physicians
Opioid Analgesics
Nonprescription Drugs

Prescription drug monitoring program design and function: A qualitative analysis

Rutkow, L., Smith, K. C., Lai, A. Y., Vernick, J. S., Davis, C. S. & Alexander, G. C. Nov 1 2017 In : Drug and Alcohol Dependence. 180, p. 395-400 6 p.

Research output: Research - peer-reviewArticle

Prescription Drugs
Drug Monitoring
Monitoring
State Government
Law Enforcement

Relationship between high-risk patients receiving prescription opioids and high-volume opioid prescribers

Chang, H. Y., Murimi, I. B., Jones, C. M. & Alexander, G. C. Jan 1 2017 (Accepted/In press) In : Addiction.

Research output: Research - peer-reviewArticle

Opioid Analgesics
Prescriptions
Morphine
Pharmacies
Benzodiazepines

The availability of pharmacies in the United States: 2007–2015

Qato, D. M., Zenk, S., Wilder, J., Harrington, R., Gaskin, D. & Alexander, G. C. Aug 1 2017 In : PLoS ONE. 12, 8, e0183172

Research output: Research - peer-reviewArticle

Pharmacies
Availability
drug therapy
Population
Prescriptions

Treatment of atrial fibrillation with warfarin among older adults with end stage renal disease

Tan, J., Bae, S., Segal, J. B., Zhu, J., Segev, D. L., Alexander, G. C. & McAdams-DeMarco, M. Dec 1 2017 In : Journal of Nephrology. 30, 6, p. 831-839 9 p.

Research output: Research - peer-reviewArticle

Warfarin
Atrial Fibrillation
Chronic Kidney Failure
Therapeutics
Dialysis
2016

Cardiovascular risks associated with clarithromycin

Iyer, G. & Alexander, G. C. Jan 14 2016 In : BMJ (Online). 352, i23

Research output: Research - peer-reviewArticle

Clarithromycin
Amoxicillin
Helicobacter Infections
Helicobacter pylori
Respiratory Tract Infections

Changes in prescription and over-the-counter medication and dietary supplement use among older adults in the United States, 2005 vs 2011

Qato, D. M., Wilder, J., Schumm, L. P., Gillet, V. & Alexander, G. C. Apr 1 2016 In : JAMA Internal Medicine. 176, 4, p. 473-482 10 p.

Research output: Research - peer-reviewArticle

Dietary Supplements
Prescriptions
Drug Interactions
Pharmaceutical Preparations
Independent Living

Editorialists' reply to Blake

Iyer, G. & Alexander, G. C. Mar 8 2016 In : BMJ (Online). 352, i1345

Research output: Research - peer-reviewArticle

Clarithromycin
Amoxicillin
Helicobacter Infections
Helicobacter pylori
Respiratory Tract Infections

Effect of Adherence to Oral Anticoagulants on Risk of Stroke and Major Bleeding Among Patients With Atrial Fibrillation

Yao, X., Abraham, N. S., Caleb Alexander, G., Crown, W., Montori, V. M., Sangaralingham, L. R., Gersh, B. J., Shah, N. D. & Noseworthy, P. A. 2016 In : Journal of the American Heart Association. 5, 2, p. 1-12 12 p.

Research output: Research - peer-reviewArticle

Anticoagulants
Atrial Fibrillation
Stroke
Hemorrhage
Warfarin

Effect of a "pill mill" law on opioid prescribing and utilization: The case of Texas

Lyapustina, T., Rutkow, L., Chang, H. Y., Daubresse, M., Ramji, A. F., Faul, M., Stuart, E. A. & Alexander, G. C. Feb 1 2016 In : Drug and Alcohol Dependence. 159, p. 190-197 8 p.

Research output: Research - peer-reviewArticle

Opioid Analgesics
Prescriptions
Confidence Intervals
Morphine
Pain Clinics

Effect of Prescription Drug Coupons on Statin Utilization and Expenditures: A Retrospective Cohort Study

Daubresse, M., Andersen, M., Riggs, K. R. & Alexander, G. C. 2016 (Accepted/In press) In : Pharmacotherapy.

Research output: Research - peer-reviewArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Prescription Drugs
Health Expenditures
Cohort Studies
Retrospective Studies

Effects of Televised Direct-to-Consumer Advertising for Varenicline on Prescription Dispensing in the United States, 2006-2009

Kim, Y., Kornfield, R., Shi, Y., Vera, L., Daubresse, M., Caleb Alexander, G. & Emery, S. May 1 2016 In : Nicotine and Tobacco Research. 18, 5, ntv198

Research output: Research - peer-reviewArticle

Prescriptions
Varenicline
Direct-to-Consumer Advertising
Safety
Tobacco Use Cessation
Benzodiazepines
Hospital Emergency Service
Hypnotics and Sedatives
Substance-Related Disorders
Age Groups
Nursing Homes
Analgesics
Pain
Prescriptions
Odds Ratio

How polypharmacy has become a medical burden worldwide

Barrett, K., Lucas, E. & Alexander, G. C. Jun 1 2016 In : Clinical Pharmacist. 8, 6

Research output: Research - peer-reviewArticle

Polypharmacy

Impact of HIE drug formularies on patient out-of-pocket costs

Andersen, M. S., Buttorff, C. & Alexander, G. C. Nov 1 2016 In : American Journal of Pharmacy Benefits. 8, 6, p. 220-226 7 p.

Research output: Research - peer-reviewArticle

Health Insurance Exchanges
Formularies
Health Expenditures
Pharmaceutical Preparations
Drugs
Prescription Drugs
Drug Monitoring
Opioid Analgesics
Interrupted Time Series Analysis
Time series analysis

Inappropriate Fentanyl Prescribing Among Nursing Home Residents in the United States

Fain, K. M., Castillo-Salgado, C., Dore, D. D., Segal, J. B., Zullo, A. R. & Alexander, G. C. 2016 (Accepted/In press) In : Journal of the American Medical Directors Association.

Research output: Research - peer-reviewArticle

Inappropriate Prescribing
Fentanyl
Nursing Homes
Opioid Analgesics
Pain

Maximizing the Post-Approval Safety of Flibanserin: A Role for Regulators, Clinicians, and Patients

Baksh, S. N., Gellad, W. F. & Alexander, G. C. Jan 21 2016 (Accepted/In press) In : Drug Safety. p. 1-6 6 p.

Research output: Research - peer-reviewArticle

United States Food and Drug Administration
Safety
flibanserin
Drug interactions
Labels

Prescribing patterns of novel anticoagulants within a statewide multispecialty practice

Efird, L. E., Chasler, J., Alexander, G. C. & McGuire, M. May 1 2016 In : American Journal of Pharmacy Benefits. 8, 3, p. 97-102 6 p.

Research output: Research - peer-reviewArticle

Anticoagulants
Prescribing
Atrial Fibrillation
Atrial fibrillation
Warfarin

Prescriptions, nonmedical use, and emergency department visits involving prescription stimulants

Chen, L. Y., Crum, R. M., Strain, E. C., Caleb Alexander, G., Kaufmann, C. & Mojtabai, R. Mar 1 2016 In : Journal of Clinical Psychiatry. 77, 3, p. e297-e304

Research output: Research - peer-reviewArticle

Prescriptions
Hospital Emergency Service
Surveys and Questionnaires
Methylphenidate
Therapeutics

Primary care physicians' knowledge and attitudes regarding prescription opioid abuse and diversion

Hwang, C. S., Turner, L. W., Kruszewski, S. P., Kolodny, A. & Caleb Alexander, G. Mar 4 2016 In : Clinical Journal of Pain. 32, 4, p. 279-284 6 p.

Research output: Research - peer-reviewArticle

Primary Care Physicians
Opioid Analgesics
Prescriptions
Physicians
Morbidity

Trends in prescribing of sedative-hypnotic medications in the USA: 1993–2010

Kaufmann, C. N., Spira, A. P., Alexander, G. C., Rutkow, L. & Mojtabai, R. Jun 1 2016 In : Pharmacoepidemiology and Drug Safety. 25, 6, p. 637-645 9 p.

Research output: Research - peer-reviewArticle

Hypnotics and Sedatives
Benzodiazepines
Sleep Wake Disorders
Health Care Surveys
Sleep Initiation and Maintenance Disorders

Using Certification to Promote Uptake of Real-World Evidence by Payers

Segal, J. B., Kallich, J. D., Oppenheim, E. R., Garrison, L. P., Iqbal, S. U., Kessler, M. & Alexander, G. C. Mar 1 2016 In : Journal of managed care & specialty pharmacy. 22, 3, p. 191-196 6 p.

Research output: Research - peer-reviewArticle

Certification
Observational Studies
Quality assurance
Organizations
Accreditation
2015

Adherence and HIV RNA suppression in the current era of highly active antiretroviral therapy

Viswanathan, S., Justice, A. C., Caleb Alexander, G., Brown, T. T., Gandhi, N. R., McNicholl, I. R., Rimland, D., Rodriguez-Barradas, M. C. & Jacobson, L. P. 2015 In : Journal of Acquired Immune Deficiency Syndromes. 69, 4, p. 493-498 6 p.

Research output: Research - peer-reviewArticle

Highly Active Antiretroviral Therapy
HIV
RNA
Veterans
Reverse Transcriptase Inhibitors

Adherence to a novel oral anticoagulant among patients with atrial fibrillation

Zhou, M., Chang, H. Y., Segal, J. B., Alexander, G. C. & Singh, S. 2015 In : Journal of Managed Care Pharmacy. 21, 11, p. 1054-1062 9 p.

Research output: Research - peer-reviewArticle

Anticoagulants
Atrial Fibrillation
Dabigatran
Therapeutics
Health

Comparative risk of gastrointestinal bleeding with dabigatran, rivaroxaban, and warfarin: Population based cohort study

Abraham, N. S., Singh, S., Caleb Alexander, G., Heien, H., Haas, L. R., Crown, W. & Shah, N. D. Apr 24 2015 In : BMJ (Online). 350, h1857

Research output: Research - peer-reviewArticle

Warfarin
Cohort Studies
Hemorrhage
Population
Rivaroxaban

Comparing employer-sponsored and federal exchange plans: Wide variations in cost sharing for prescription drugs

Buttorff, C., Andersen, M. S., Riggs, K. R. & Caleb Alexander, G. 2015 In : Health Affairs. 34, 3, p. 467-476 10 p.

Research output: Research - peer-reviewArticle

Cost Sharing
Prescription Drugs
Pharmaceutical Preparations
Health Insurance Exchanges
Names

Construct validity and factor structure of survey-based assessment of cost-related medication burden

Burcu, M., Alexander, G. C., Ng, X. & Harrington, D. Feb 2 2015 In : Medical Care. 53, 2, p. 199-206 8 p.

Research output: Research - peer-reviewArticle

Costs and Cost Analysis
Surveys and Questionnaires
Medication Adherence
Medicare
Pharmaceutical Preparations

Cost Containment and Patient Well-Being

Riggs, K. R. & Alexander, G. C. Jun 26 2015 In : Journal of General Internal Medicine. 30, 6, p. 701-702 2 p.

Research output: Research - peer-reviewArticle

Cost Control
Hospital Mortality
Teaching Hospitals
Length of Stay

Effect of direct-to-consumer advertising on asthma medication sales and healthcare use

Daubresse, M., Hutfless, S., Kim, Y., Kornfield, R., Qato, D. M., Huang, J., Miller, K., Emery, S. L. & Alexander, G. C. Jul 1 2015 In : American Journal of Respiratory and Critical Care Medicine. 192, 1, p. 40-46 7 p.

Research output: Research - peer-reviewArticle

Asthma
Delivery of Health Care
Direct-to-Consumer Advertising
Prescriptions
Hospital Emergency Service
Prescription Drugs
Drug Monitoring
Opioid Analgesics
Morphine
Prescriptions

Emergency department visits by children and adolescents for antipsychotic drug adverse events

Hampton, L. M., Daubresse, M., Chang, H. Y., Alexander, G. C. & Budnitz, D. S. Mar 1 2015 In : JAMA Psychiatry. 72, 3, p. 292-294 3 p.

Research output: Research - peer-reviewArticle

Postmarketing Product Surveillance
Drug-Related Side Effects and Adverse Reactions
Antipsychotic Agents
Hospital Emergency Service
Hospitalization

Evaluation of flibanserin science and advocacy at the FDA

Gellad, W. F., Flynn, K. E. & Alexander, G. C. Sep 1 2015 In : Journal of the American Medical Association. 314, 9, p. 869-870 2 p.

Research output: Research - peer-reviewArticle

How do payers respond to regulatory actions? The case of bevacizumab

Dusetzina, S. B., Ellis, S., Freedman, R. A., Conti, R. M., Winn, A. N., Chambers, J. D., Alexander, G. C., Huskamp, H. A. & Keating, N. L. Jul 1 2015 In : Journal of Oncology Practice. 11, 4, p. 313-318 6 p.

Research output: Research - peer-reviewArticle

Bevacizumab
Medicare
Breast Neoplasms
United States Food and Drug Administration
Lung Neoplasms

Impact of abuse-deterrent OxyContin on prescription opioid utilization

Hwang, C. S., Chang, H. Y. & Alexander, G. C. Feb 1 2015 In : Pharmacoepidemiology and Drug Safety. 24, 2, p. 197-204 8 p.

Research output: Research - peer-reviewArticle

Oxycodone
Opioid Analgesics
Prescriptions
Health
Marketing

Impact of Out-of-Pocket Spending Caps on Financial Burden of those with Group Health Insurance

Riggs, K. R., Buttorff, C. & Alexander, G. C. May 1 2015 In : Journal of General Internal Medicine. 30, 5, p. 683-688 6 p.

Research output: Research - peer-reviewArticle

Health Insurance
Health Expenditures
Delivery of Health Care
Surveys and Questionnaires
Health Insurance Exchanges

Most primary care physicians are aware of prescription drug monitoring programs, but many find the data difficult to access

Rutkow, L., Turner, L., Lucas, E., Hwang, C. & Caleb Alexander, G. 2015 In : Health Affairs. 34, 3, p. 484-492 9 p.

Research output: Research - peer-reviewArticle

Prescription Drugs
Drug Monitoring
Primary Care Physicians
Physicians
Surveys and Questionnaires

National trends in ambulatory oral anticoagulant use

Barnes, G. D., Lucas, E., Alexander, G. C. & Goldberger, Z. D. Dec 1 2015 In : American Journal of Medicine. 128, 12, p. 1300-1305e5

Research output: Research - peer-reviewArticle

Anticoagulants
Therapeutics
Warfarin
Atrial Fibrillation
Confidence Intervals

National trends in the ambulatory treatment of hypertension in the United States, 1997-2012

Zhou, M., Daubresse, M., Stafford, R. S. & Alexander, G. C. Mar 4 2015 In : PLoS One. 10, 3, e0119292

Research output: Research - peer-reviewArticle

hypertension
therapeutics
Hypertension
Therapeutics
Antihypertensive Agents

Prescription drug abuse: A national survey of primary care physicians

Hwang, C. S., Turner, L. W., Kruszewski, S. P., Kolodny, A. & Alexander, G. C. Feb 1 2015 In : JAMA Internal Medicine. 175, 2, p. 302-304 3 p.

Research output: Research - peer-reviewArticle

Prescription Drug Misuse
Attitude of Health Personnel
Prescription Drugs
Primary Care Physicians
Opioid Analgesics

Racial disparities in reaching the renal transplant waitlist: Is geography as important as race?

Saunders, M. R., Lee, H., Alexander, G. C., Tak, H. J., Thistlethwaite, J. R. & Ross, L. F. Jun 1 2015 In : Clinical Transplantation. 29, 6, p. 531-538 8 p.

Research output: Research - peer-reviewArticle

Geography
African Americans
Transplants
Kidney
Chronic Kidney Failure