Gehua Zhen

Instructor

20062018
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Research Output 2006 2018

Aberrant TGF-β activation in bone tendon insertion induces enthesopathy-like disease

Wang, X., Xie, L., Crane, J., Zhen, G., Li, F., Yang, P., Gao, M., Deng, R., Wang, Y., Jia, X., Fan, C., Wan, M. & Cao, X., Feb 1 2018, In : Journal of Clinical Investigation. 128, 2, p. 846-860 15 p.

Research output: Contribution to journalArticle

Achilles Tendon
Transforming Growth Factor beta
Tendons
Fibrocartilage
Mesenchymal Stromal Cells

Bone-targeted delivery of TGF-β type 1 receptor inhibitor rescues uncoupled bone remodeling in Camurati–Engelmann disease

Qin, Y., Tang, S., Zhen, G., Ding, Q., Ding, S. & Cao, X., Jan 1 2018, (Accepted/In press) In : Annals of the New York Academy of Sciences.

Research output: Contribution to journalArticle

Camurati-Engelmann Syndrome
Transforming Growth Factor beta1
Transforming Growth Factor beta Receptors
Bone Remodeling
Bone and Bones

Inhibition of overactive TGF-β attenuates progression of heterotopic ossification in mice

Wang, X., Li, F., Xie, L., Crane, J., Zhen, G., Mishina, Y., Deng, R., Gao, B., Chen, H., Liu, S., Yang, P., Gao, M., Tu, M., Wang, Y., Wan, M., Fan, C. & Cao, X., Dec 1 2018, In : Nature Communications. 9, 1, 551

Research output: Contribution to journalArticle

Heterotopic Ossification
osteogenesis
progressions
Transforming Growth Factor beta
mice

Long-term feasibility and biocompatibility of directly microsurgically implanted intrafascicular electrodes in free roaming rabbits

Zhen, G., Chen, H., Tsai, S. Y., Zhang, J., Chen, T. & Jia, X., Jan 1 2018, (Accepted/In press) In : Journal of Biomedical Materials Research - Part B Applied Biomaterials.

Research output: Contribution to journalArticle

Biocompatibility
Electrodes
Tissue
Prosthetics
Electron microscopy

Mechanically induced Ca2+ oscillations in osteocytes release extracellular vesicles and enhance bone formation

Morrell, A. E., Brown, G. N., Robinson, S. T., Sattler, R. L., Baik, A. D., Zhen, G., Cao, X., Bonewald, L. F., Jin, W., Kam, L. C. & Guo, X. E., Dec 1 2018, In : Bone Research. 6, 1, 6

Research output: Contribution to journalArticle

Osteocytes
Lysosomal-Associated Membrane Protein 1
Osteogenesis
Neomycin
Bone and Bones