Gary William Goldstein

Professor

1964 …2004
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Research Output 1964 2004

2004

Editorial introductions

Goldstein, G. W. & Chauvel, P. Y. Apr 2004 In : Current Opinion in Neurology. 17, 2

Research output: Contribution to journalArticle

Static encephalopathies become dynamic

Goldstein, G. W. Apr 2004 In : Current Opinion in Neurology. 17, 2, p. 93-94 2 p.

Research output: Contribution to journalArticle

Chronic Brain Damage
Learning Disorders
Brain Diseases
Cerebral Palsy
Intellectual Disability
2003

Development of the Blood-Brain Barrier

Laterra, J. & Goldstein, G. W. Dec 1 2003 Fetal and Neonatal Physiology: Third Edition. Saunders, Vol. 2-2, p. 1699-1706 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Blood-Brain Barrier
2002
AIDS-Related Complex
Electroshock
Protein Kinase C
Convulsants
Messenger RNA
2000

Immediate early gene expression in PC12 cells exposed to lead: Requirement for protein kinase C

Kim, K. A., Chakraborti, T., Goldstein, G. W. & Bressler, J. P. 2000 In : Journal of Neurochemistry. 74, 3, p. 1140-1146 7 p.

Research output: Contribution to journalArticle

Immediate-Early Genes
PC12 Cells
Gene expression
Protein Kinase C
Gene Expression
Rodentia
Neocortex
Vibrissae
Sensory Receptor Cells
Intelligence

Safety and efficacy of succimer in toddlers with blood lead levels of 20-44 μg/dL

Rogan, W. J. , Bornschein, R. L. , Chisolm J.J., J. , Damokosh, A. I. , Dockery, D. W. , Fay, M. E. , Jones, R. L. , Rhoads, G. G. , Ragan, N. B. , Salganik, M. , Schwarz, D. F. , Ware, J. H. , Wedeen, R. P. , Serwint, J. , Brophy, M. , Davoli, C. T. , Denckla, M. B. , Farfel, M. R. , Goldstein, G. W. , Rubin, J. & 32 others Berger, O., Dietrich, K. N., Wesolowski, C., Wilkins, S., Maynard-Wentzel, G., Mortensen, M. E., Adubato, S., Elsafty, M., Heenehan, M., Sheffet, A., Ty, A., Campbell, C., Gill, F. M., Guinn, J., Henretig, F., Knight, D., Radcliffe, J., Schwarz, D. F., Bowman, B. B., Gunter, E., Huff, D., Miller, D. T., Paschal, D. C., Bernstein, A. J., Kotlov, T. V., Angle, C. R., Faison, J., Gehlbach, S. H., Gray-Little, B., James, S. A., Moye, L. A. & Needleman, H. L. 2000 In : Pediatric Research. 48, 5, p. 593-599 7 p.

Research output: Contribution to journalArticle

Succimer
Safety
Placebos
Wounds and Injuries
Brain Diseases
1999

Increased AP-1 DNA binding activity in PC12 cells treated with lead

Chakraborti, T., Kim, K. A., Goldstein, G. G. & Bressler, J. P. 1999 In : Journal of Neurochemistry. 73, 1, p. 187-194 8 p.

Research output: Contribution to journalArticle

PC12 Cells
Transcription Factor AP-1
Protein Kinase C
DNA
Transcription

Molecular mechanisms of lead neurotoxicity

Dressier, J., Kim, K. A., Chakraborti, T. & Goldstein, G. 1999 In : Neurochemical Research. 24, 4, p. 595-600 6 p.

Research output: Contribution to journalArticle

Protein Kinase C
Blood
Learning
Calcium
Synapses
1998

Selective vulnerability of the developing brain to lead

Johnston, M. V. & Goldstein, G. W. 1998 In : Current Opinion in Neurology. 11, 6, p. 689-693 5 p.

Research output: Contribution to journalArticle

Aptitude
Paint
Environmental Exposure
Glutamate Receptors
Brain
1997

Induction of c-foS mRNA by lead in PC12 cells

Kim, K., Annadata, M., Goldstein, G. W. & Bressler, J. P. Apr 1997 In : International Journal of Developmental Neuroscience. 15, 2, p. 175-182 8 p.

Research output: Contribution to journalArticle

PC12 Cells
Messenger RNA
fos Genes
Cadmium Chloride
Immediate-Early Genes
1996

Benzene exposure, assessed by urinary trans, trans muconic acid, in urban children with elevated blood lead levels

Weaver, V. M., Davoli, C. T., Heller, P. J., Fitzwilliam, A., Peters, H. L., Sunyer, J., Murphy, S. E., Goldsiein, G. W. & Groopman, J. D. 1996 In : Environmental Health Perspectives. 104, 3, p. 318-323 6 p.

Research output: Contribution to journalArticle

Benzene
benzene
Blood
blood
Environmental Exposure

Distinct mechanisms of neurotransmitter release from PC 12 cells exposed to lead

Bressler, J. P., Belloni-Olivi, L., Forman, S. & Goldstein, G. W. 1996 In : Journal of Neuroscience Research. 46, 6, p. 678-685 8 p.

Research output: Contribution to journalArticle

Neurotransmitter Agents
Thapsigargin
Norepinephrine
Protein Kinase C
Acetates

Modulation of serine proteinases and metalloproteinases during morphogenic glial-endothelial interactions

Rao, J. S., Sawaya, R., Gokaslan, Z. L., Yung, W. K. A., Goldstein, G. W. & Laterra, J. Apr 1996 In : Journal of Neurochemistry. 66, 4, p. 1657-1664 8 p.

Research output: Contribution to journalArticle

Urokinase-Type Plasminogen Activator
Metalloproteases
Serine Proteases
Neuroglia
Collagenases

Phosphorylation of membrane proteins in erythrocytes treated with lead

Belloni-Olivi, L., Annadata, M., Goldstein, G. W. & Bressler, J. P. Apr 15 1996 In : Biochemical Journal. 315, 2, p. 401-406 6 p.

Research output: Contribution to journalArticle

Phosphorylation
Membrane Proteins
Erythrocytes
Protein Kinase C
Membranes
Sulfhydryl Compounds
Anions
Potassium
Erythrocytes
Sulfhydryl Reagents
1995

Enhanced endothelial cell adhesion of human cerebrospinal fluid lymphocytes

Elfont, R. M., Griffin, D. E. & Goldstein, G. W. Sep 1995 In : Annals of Neurology. 38, 3, p. 405-413 9 p.

Research output: Contribution to journalArticle

Cell Adhesion
Cerebrospinal Fluid
Endothelial Cells
Lymphocytes
Central Nervous System
1994

Blood-brain barrier in toxic encephalopathies

Goldstein, G. W. 1994 In : Neurobiology of Aging. 15, 2, p. 237-238 2 p.

Research output: Contribution to journalArticle

Neurotoxicity Syndromes
Brain Diseases
Blood-Brain Barrier
Cell Tracking
beta-Galactosidase
Microvessels
Lac Operon
Staining and Labeling

Endothelial cell implantation and survival within experimental gliomas

Lal, B., Indurti, R. R., Couraud, P. O., Goldstein, G. W. & Laterra, J. Oct 11 1994 In : Proceedings of the National Academy of Sciences of the United States of America. 91, 21, p. 9695-9699 5 p.

Research output: Contribution to journalArticle

Glioma
Cell Survival
Endothelial Cells
Brain Neoplasms
Neoplasms

Lead debate goes on [5]

Chisholm, J., Goldstein, G., Cory-Slechta, D., Weiss, B., Landrigan, P., Mushak, P., Needleman, H. L., Rice, D., Rosen, J., Silbergeld, E. & Harvey, B. 1994 In : Pediatrics. 94, 3, p. 408-410 3 p.

Research output: Contribution to journalArticle

Endothelial cells
Arachidonic Acid
Metabolism
Phospholipids
Ionomycin

Regulation of in vitro glia-induced microvessel morphogenesis by urokinase

Laterra, J., Indurti, R. R. & Goldstein, G. W. Feb 1994 In : Journal of Cellular Physiology. 158, 2, p. 317-324 8 p.

Research output: Contribution to journalArticle

Urokinase-Type Plasminogen Activator
Coculture Techniques
Microvessels
Morphogenesis
Neuroglia
1993

Dexamethasone reduces vascular density and plasminogen activator activity in 9L rat brain tumors

Wolff, J. E. A., Guerin, C., Laterra, J., Bressler, J., Indurti, R. R., Brem, H. & Goldstein, G. W. Feb 26 1993 In : Brain Research. 604, 1-2, p. 79-85 7 p.

Research output: Contribution to journalArticle

Plasminogen Activators
Brain Neoplasms
Dexamethasone
Blood Vessels
Growth

Evidence that lead acts as a calcium substitute in second messenger metabolism

Goldstein, G. W. 1993 In : NeuroToxicology. 14, 2-3, p. 97-102 6 p.

Research output: Contribution to journalArticle

Second Messenger Systems
Metabolism
Protein Kinase C
Calcium
Calmodulin

Plasminogen activation and astroglial-induced neural microvessel morphogenesis

Laterra, J., Indurti, R. R. & Goldstein, G. W. 1993 Advances in Experimental Medicine and Biology. Vol. 331, p. 189-199 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Plasminogen Activators
Plasminogen
Vascular Endothelium
Microcirculation
Microvessels
1992
Phosphatidylinositol Phosphates
Astrocytes
Endothelial Cells
Glucose
Type C Phospholipases

Formation and differentiation of brain capillaries.

Laterra, J., Wolff, J. E., Guerin, C. & Goldstein, G. W. 1992 In : NIDA research monograph. 120, p. 73-86 14 p.

Research output: Contribution to journalArticle

Blood-Brain Barrier
Astrocytes
Brain
Astrocytes
Protein Kinase C
Central Nervous System
Endothelial Cells
Phorbol Esters

Neurologic concepts of lead poisoning in children.

Goldstein, G. W. Jun 1992 In : Pediatric Annals. 21, 6, p. 384-388 5 p.

Research output: Contribution to journalArticle

Nervous System Lead Poisoning
Chelation Therapy
Lead Poisoning
Paint
Intestinal Absorption

Retinal microvessels express less gamma-glutamyl transpeptidase than brain microvessels

Belloni-Olivi, L., Brassier, J. P. & Goldstein, G. W. 1992 In : Current Eye Research. 11, 3, p. 203-211 9 p.

Research output: Contribution to journalArticle

gamma-Glutamyltransferase
Microvessels
Brain
Alkaline Phosphatase
Choroid Plexus

Steroid inhibition of neural microvessel morphogenesis in vitro: Receptor mediation and astroglial dependence

Wolff, J. E. A., Laterra, J. & Goldstein, G. W. Mar 1992 In : Journal of Neurochemistry. 58, 3, p. 1023-1032 10 p.

Research output: Contribution to journalArticle

Neural Inhibition
Endothelial cells
Microvessels
Morphogenesis
Steroids

Vascular differentiation and glucose transporter expression in rat gliomas: Effects of steroids

Guerin, C., Wolff, J. E. A., Laterra, J., Drewes, L. R., Brem, H. & Goldstein, G. W. May 1992 In : Annals of Neurology. 31, 5, p. 481-487 7 p.

Research output: Contribution to journalArticle

Facilitative Glucose Transport Proteins
Glioma
Blood Vessels
Steroids
Dexamethasone

Vascular expression of glucose transporter in experimental brain neoplasms

Guerin, C., Laterra, J., Drewes, L. R., Brem, H. & Goldstein, G. W. Feb 1992 In : American Journal of Pathology. 140, 2, p. 417-425 9 p.

Research output: Contribution to journalArticle

Experimental Neoplasms
Facilitative Glucose Transport Proteins
Brain Neoplasms
Blood Vessels
Microvessels

γ-glutamyl transpeptidase activity in brain microvessels exhibits regional heterogeneity

Wolff, J. E. A., Belloni-Olivi, L., Bressler, J. P. & Goldstein, G. W. Mar 1992 In : Journal of Neurochemistry. 58, 3, p. 909-915 7 p.

Research output: Contribution to journalArticle

gamma-Glutamyltransferase
Microvessels
Brain
Neocortex
Rats
1991

Astroglial-induced in vitro angiogenesis: Requirements for RNA and protein synthesis

Laterra, J. & Goldstein, G. W. Oct 1991 In : Journal of Neurochemistry. 57, 4, p. 1231-1239 9 p.

Research output: Contribution to journalArticle

Microvessels
Endothelial cells
RNA
Brain
Retina

Mechanisms of lead neurotoxicity

Bressler, J. P. & Goldstein, G. W. Feb 15 1991 In : Biochemical Pharmacology. 41, 4, p. 479-484 6 p.

Research output: Contribution to journalArticle

Brain
Endothelial cells
Blood-Brain Barrier
Protein Kinases
Endothelial Cells
1990

Astrocytes induce neural microvascular endothelial cells to form capillary-like structures in vitro

Laterra, J., Guerin, C. & Goldstein, G. W. Aug 1990 In : Journal of Cellular Physiology. 144, 2, p. 204-215 12 p.

Research output: Contribution to journalArticle

Endothelial cells
Astrocytes
Coculture Techniques
Endothelial Cells
Conditioned Culture Medium

Intellective functioning and strategy use in children with insulin-dependent diabetes mellitus.

Hagen, J. W., Barclay, C. R., Anderson, B. J., Feeman, D. J., Segal, S. S., Bacon, G. & Goldstein, G. W. Dec 1990 In : Child Development. 61, 6, p. 1714-1727 14 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
chronic illness
Parents
parents
Aptitude

Lead poisoning and brain cell function

Goldstein, G. W. 1990 In : Environmental Health Perspectives. 89, p. 91-94 4 p.

Research output: Contribution to journalArticle

Industrial poisons
Lead Poisoning
poisoning
Protein Kinases
brain

Myo-inositol transport into endothelial cells derived from nervous system microvessels

Kollros, P. E., Goldstein, G. W. & Betz, A. L. Mar 19 1990 In : Brain Research. 511, 2, p. 259-264 6 p.

Research output: Contribution to journalArticle

Inositol
Microvessels
Nervous System
Endothelial Cells
Central Nervous System
Adenine Nucleotides
Epoprostenol
Phosphatidylinositols
Endothelium
Prostaglandins F

The glucose transporter and blood-brain barrier of human brain tumors

Guerin, C., Laterra, J., Hruban, R. H., Brem, H., Drewes, L. R. & Goldstein, G. W. Dec 1990 In : Annals of Neurology. 28, 6, p. 758-765 8 p.

Research output: Contribution to journalArticle

Facilitative Glucose Transport Proteins
Blood-Brain Barrier
Brain Neoplasms
Astrocytoma
Capillary Permeability
1989

Lead contamination [18]

Markovac, J. & Goldstein, G. W. 1989 In : Nature. 337, 6207, p. 514 1 p.

Research output: Contribution to journalArticle

Use of intravenous immune globulin in the treatment of seizure disorders

Schwartz, S. A., Gordon, K. E., Johnston, M. V. & Goldstein, G. W. 1989 In : The Journal of Allergy and Clinical Immunology. 84, 4 PART 2, p. 603-607 5 p.

Research output: Contribution to journalArticle

Intravenous Immunoglobulins
Epilepsy
Seizures
Humoral Immunity
Therapeutics

Use of intravenous immune globulin in the treatment of seizure disorders

Schwartz, S. A., Gordon, K. E., Johnston, M. V. & Goldstein, G. W. 1989 In : The Journal of Allergy and Clinical Immunology. 84, 4 II SUPPL., p. 603-607 5 p.

Research output: Contribution to journalArticle

Intravenous Immunoglobulins
Epilepsy
Seizures
Humoral Immunity
Therapeutics
1988

Correspondence

Mullen, K. D., Szauter, K. M., McCullough, A. J., Lo, W. D., McNeely, D. L., Ennis, S. R., Goldstein, G. W., Betz, A. L., Henderson, J. M., Kutner, M. H., Warren, W. D., Terés, J., Myslobodsky, M. S., Baktir, G., Fisch, H. U., Karlaganis, G., Minder, C. & Bircher, J. 1988 In : Hepatology. 8, 2, p. 440-441 2 p.

Research output: Contribution to journalLetter

EEG abnormalities aid diagnosis of Rett syndrome

Garofalo, E. A., Drury, I. & Goldstein, G. W. 1988 In : Pediatric Neurology. 4, 6, p. 350-353 4 p.

Research output: Contribution to journalArticle

Rett Syndrome
Electroencephalography
Sleep
Seizures
Wakefulness
Endothelial cells
Blood-Brain Barrier
Cell Communication
Astrocytes
Endothelial Cells

Heparin inhibits the growth of astrocytes in vitro

Robertson, P. L. & Goldstein, G. W. May 3 1988 In : Brain Research. 447, 2, p. 341-345 5 p.

Research output: Contribution to journalArticle

Astrocytes
Heparin
Growth
Serum
Thymidine