Gabsang Lee

Associate Professor

20032020

Research output per year

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Research Output

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Article
2020

Inhibitory effect of therapeutic genes, cytosine deaminase and interferon-β, delivered by genetically engineered stem cells against renal cell carcinoma

Kim, G. S., Kim, S. M., Kim, S. U., Lee, G. & Choi, K. C., Jan 1 2020, In : Oncology reports. 43, 6, p. 2045-2052 8 p.

Research output: Contribution to journalArticle

Transcriptional landscape of myogenesis from human pluripotent stem cells reveals a key role of TWIST1 in maintenance of skeletal muscle progenitors

Choi, I. Y., Lim, H., Cho, H. J., Oh, Y., Chou, B. K., Bai, H., Cheng, L., Kim, Y. J., Hyun, S., Kim, H., Shin, J. H. & Lee, G., Feb 2020, In : eLife. 9, e46981.

Research output: Contribution to journalArticle

Open Access
2019

Characterization of canine adipose tissue-derived mesenchymal stem cells immortalized by SV40-T retrovirus for therapeutic use

Ayala-Cuellar, A. P., Kim, C. W., Hwang, K. A., Kang, J. H., Lee, G., Cho, J. & Choi, K. C., Jan 1 2019, In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Comparison of three congruent patient-specific cell types for the modelling of a human genetic Schwann-cell disorder

Mukherjee-Clavin, B., Mi, R., Kern, B., Choi, I. Y., Lim, H., Oh, Y., Lannon, B., Kim, K. J., Bell, S., Hur, J. K., Hwang, W., Che, Y. H., Habib, O., Baloh, R. H., Eggan, K., Brandacher, G., Hoke, A., Studer, L., Kim, Y. J. & Lee, G., Jan 1 2019, In : Nature Biomedical Engineering.

Research output: Contribution to journalArticle

GDF8 enhances SOX2 expression and blastocyst total cell number in porcine IVF embryo development

Yoon, J. D., Hwang, S. U., Kim, M., Lee, G., Jeon, Y. & Hyun, S. H., Apr 15 2019, In : Theriogenology. 129, p. 70-76 7 p.

Research output: Contribution to journalArticle

Neural induction of porcine-induced pluripotent stem cells and further differentiation using glioblastoma-cultured medium

Kim, E., Kim, M., Hwang, S. U., Kim, J., Lee, G., Park, Y. S. & Hyun, S. H., Jan 1 2019, (Accepted/In press) In : Journal of Cellular and Molecular Medicine.

Research output: Contribution to journalArticle

Role of Human-Induced Pluripotent Stem Cell-Derived Spinal Cord Astrocytes in the Functional Maturation of Motor Neurons in a Multielectrode Array System

Taga, A., Dastgheyb, R., Habela, C., Joseph, J., Richard, J. P., Gross, S. K., Lauria, G., Lee, G., Haughey, N. & Maragakis, N. J., Jan 1 2019, (Accepted/In press) In : Stem Cells Translational Medicine.

Research output: Contribution to journalArticle

Open Access

Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease

Kim, S., Kwon, S. H., Kam, T. I., Panicker, N., Karuppagounder, S. S., Lee, S., Lee, J. H., Kim, W. R., Kook, M., Foss, C. A., Shen, C., Lee, H., Kulkarni, S., Pasricha, P. J., Lee, G., Pomper, M. G., Dawson, V. L., Dawson, T. M. & Ko, H. S., Aug 21 2019, In : Neuron. 103, 4, p. 627-641.e7

Research output: Contribution to journalArticle

2018

GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers

Kim, S., Yun, S. P., Lee, S., Umanah, G., Bandaru, V. V. R., Yin, X., Rhee, P., Karuppagounder, S., Kwon, S. H., Lee, H., Mao, X., Kim, D., Pandey, A., Lee, G., Dawson, V., Dawson, T. M. & Ko, H. S., Jan 23 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 4, p. 798-803 6 p.

Research output: Contribution to journalArticle

Isolation and characterization of GFAP-positive porcine neural stem/progenitor cells derived from a GFAP-CreERT2 transgenic piglet

Kim, E., Hwang, S. U., Yoon, J. D., Kim, H., Lee, G. & Hyun, S. H., Nov 7 2018, In : BMC Veterinary Research. 14, 1, 1 p.

Research output: Contribution to journalArticle

Lysophosphatidic acid increases in vitro maturation efficiency via uPA-uPAR signaling pathway in cumulus cells

Hwang, S. U., Kim, K. J., Kim, E., Yoon, J. D., Park, K. M., Jin, M., Han, Y., Kim, M., Lee, G. & Hyun, S. H., Jun 1 2018, In : Theriogenology. 113, p. 197-207 11 p.

Research output: Contribution to journalArticle

Optimal electrical stimulation boosts stem cell therapy in nerve regeneration

Du, J., Zhen, G., Chen, H., Zhang, S., Qing, L., Yang, X., Lee, G., Mao, H. Q. & Jia, X., Oct 1 2018, In : Biomaterials. 181, p. 347-359 13 p.

Research output: Contribution to journalArticle

2017

Design of a high-Throughput human neural crest cell migration assay to indicate potential developmental toxicants

Nyffeler, J., Karreman, C., Leisner, H., Kim, Y. J., Lee, G., Waldmann, T. & Leist, M., 2017, In : Altex. 34, 1, p. 75-94 20 p.

Research output: Contribution to journalArticle

Role of the JNK pathway in varicella-zoster virus lytic infection and reactivation

Kurapati, S., Sadaoka, T., Rajbhandari, L., Shukla, P., Ali, M. A., Kim, Y. J., Lee, G., Cohen, J. I. & Venkatesan, A., Sep 1 2017, In : Journal of Virology. 91, 17, e00640-17.

Research output: Contribution to journalArticle

Zika virus directly infects peripheral neurons and induces cell death

Oh, Y., Zhang, F., Wang, Y., Lee, E. M., Choi, I. Y., Lim, H., Mirakhori, F., Li, R., Huang, L., Xu, T., Wu, H., Li, C., Qin, C. F., Wen, Z., Wu, Q. F., Tang, H., Xu, Z., Jin, P., Song, H., Ming, G. L. & 1 others, Lee, G., Sep 1 2017, In : Nature neuroscience. 20, 9, p. 1209-1212 4 p.

Research output: Contribution to journalArticle

2016

Capturing the biology of disease severity in a PSC-based model of familial dysautonomia

Zeltner, N., Fattahi, F., Dubois, N. C., Saurat, N., Lafaille, F., Shang, L., Zimmer, B., Tchieu, J., Soliman, M. A., Lee, G., Casanova, J. L. & Studer, L., Dec 1 2016, In : Nature Medicine. 22, 12, p. 1421-1427 7 p.

Research output: Contribution to journalArticle

Functional Coupling with Cardiac Muscle Promotes Maturation of hPSC-Derived Sympathetic Neurons

Oh, Y., Cho, G. S., Kim, M. J., Kim, Y. J., Kwon, C. & Lee, G., Jul 1 2016, In : Cell stem cell. 19, 1, p. 95-106 12 p.

Research output: Contribution to journalArticle

PLEKHG3 enhances polarized cell migration by activating actin filaments at the cell front

Nguyen, T. T. T., Park, W. S., Park, B. O., Kim, C. Y., Oh, Y., Kim, J. M., Choi, H., Kyung, T., Kim, C. H., Lee, G., Hahn, K. M., Meyer, T. & Heo, W. D., Sep 6 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 36, p. 10091-10096 6 p.

Research output: Contribution to journalArticle

2015

A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs

Choi, J., Lee, S., Mallard, W., Clement, K., Tagliazucchi, G. M., Lim, H., Choi, I. Y., Ferrari, F., Tsankov, A. M., Pop, R., Lee, G., Rinn, J. L., Meissner, A., Park, P. J. & Hochedlinger, K., Nov 1 2015, In : Nature biotechnology. 33, 11, p. 1173-1181 9 p.

Research output: Contribution to journalArticle

A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis

Laguesse, S., Creppe, C., Nedialkova, D. D., Prévot, P. P., Borgs, L., Huysseune, S., Franco, B., Duysens, G., Krusy, N., Lee, G., Thelen, N., Thiry, M., Close, P., Chariot, A., Malgrange, B., Leidel, S. A., Godin, J. D. & Nguyen, L., 2015, In : Developmental Cell. 35, 5, p. 553-567 15 p.

Research output: Contribution to journalArticle

Concordant but Varied Phenotypes among Duchenne Muscular Dystrophy Patient-Specific Myoblasts Derived using a Human iPSC-Based Model

Choi, I. Y., Lim, H. T., Estrellas, K., Mula, J., Cohen, T. V., Zhang, Y., Donnelly, C. J., Richard, J-P., Kim, Y. J., Kim, H., Kazuki, Y., Oshimura, M., Li, H. L., Hotta, A., Rothstein, J. D., Maragakis, N. J., Wagner, K. R. & Lee, G., Sep 9 2015, (Accepted/In press) In : Cell Reports.

Research output: Contribution to journalArticle

Dual-SMAD Inhibition/WNT Activation-Based Methods to Induce Neural Crest and Derivatives from Human Pluripotent Stem Cells

Chambers, S. M., Mica, Y., Lee, G., Studer, L. & Tomishima, M. J., Jan 1 2015, In : Methods in Molecular Biology. 1307, p. 329-343 15 p.

Research output: Contribution to journalArticle

2014

Efficient generation human induced pluripotent stem cells from human somatic cells with sendai-virus

Choi, I. Y., Lim, H. T. & Lee, G., Apr 23 2014, In : Journal of Visualized Experiments. 86

Research output: Contribution to journalArticle

Generation of multipotent induced neural crest by direct reprogramming of human postnatal fibroblasts with a single transcription factor

Kim, Y. J., Lim, H., Li, Z., Oh, Y., Kovlyagina, I., Choi, I. Y., Dong, X. & Lee, G., Jan 1 2014, In : Cell stem cell. 15, 4, p. 497-506 10 p.

Research output: Contribution to journalArticle

Profiling individual human embryonic stem cells by quantitative RT-PCR

Lim, H., Choi, I. Y. & Lee, G., Jan 1 2014, In : Journal of Visualized Experiments. 87, e51408.

Research output: Contribution to journalArticle

2013

Modeling Neural Crest Induction, Melanocyte Specification, and Disease-Related Pigmentation Defects in hESCs and Patient-Specific iPSCs

Mica, Y., Lee, G., Chambers, S. M., Tomishima, M. J. & Studer, L., Apr 25 2013, In : Cell Reports. 3, 4, p. 1140-1152 13 p.

Research output: Contribution to journalArticle

2012

Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors

Chambers, S. M., Qi, Y., Mica, Y., Lee, G., Zhang, X. J., Niu, L., Bilsland, J., Cao, L., Stevens, E., Whiting, P., Shi, S. H. & Studer, L., Jul 1 2012, In : Nature biotechnology. 30, 7, p. 715-720 6 p.

Research output: Contribution to journalArticle

Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cells

Zimmer, B., Lee, G., Balmer, N. V., Meganathan, K., Sachinidis, A., Studer, L. & Leist, M., Aug 1 2012, In : Environmental health perspectives. 120, 8, p. 1116-1122 7 p.

Research output: Contribution to journalArticle

Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression

Lee, G., Ramirez, C. N., Kim, H., Zeltner, N., Liu, B., Radu, C., Bhinder, B., Kim, Y. J., Choi, I. Y., Mukherjee-Clavin, B., Djaballah, H. & Studer, L., Dec 1 2012, In : Nature biotechnology. 30, 12, p. 1244-1248 5 p.

Research output: Contribution to journalArticle

2011

Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells

Papapetrou, E. P., Lee, G., Malani, N., Setty, M., Riviere, I., Tirunagari, L. M. S., Kadota, K., Roth, S. L., Giardina, P., Viale, A., Leslie, C., Bushman, F. D., Studer, L. & Sadelain, M., Jan 1 2011, In : Nature biotechnology. 29, 1, p. 73-81 9 p.

Research output: Contribution to journalArticle

miR-371-3 expression predicts neural differentiation propensity in human pluripotent stem cells

Kim, H., Lee, G., Ganat, Y., Papapetrou, E. P., Lipchina, I., Socci, N. D., Sadelain, M. & Studer, L., Jun 3 2011, In : Cell stem cell. 8, 6, p. 695-706 12 p.

Research output: Contribution to journalArticle

Modelling familial dysautonomia in human induced pluripotent stem cells

Lee, G. & Studer, L., Jul 4 2011, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 366, 1575, p. 2286-2296 11 p.

Research output: Contribution to journalArticle

2010

Derivation of neural crest cells from human pluripotent stem cells

Lee, G., Chambers, S. M., Tomishima, M. J. & Studer, L., Apr 2010, In : Nature protocols. 5, 4, p. 688-701 14 p.

Research output: Contribution to journalArticle

Efficient Derivation of Functional Floor Plate Tissue from Human Embryonic Stem Cells

Fasano, C. A., Chambers, S. M., Lee, G., Tomishima, M. J. & Studer, L., Apr 2 2010, In : Cell stem cell. 6, 4, p. 336-347 12 p.

Research output: Contribution to journalArticle

Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFΒ inhibition is Id1 dependent

James, D., Nam, H. S., Seandel, M., Nolan, D., Janovitz, T., Tomishima, M., Studer, L., Lee, G., Lyden, D., Benezra, R., Zaninovic, N., Rosenwaks, Z., Rabbany, S. Y. & Rafii, S., Feb 1 2010, In : Nature biotechnology. 28, 2, p. 161-166 6 p.

Research output: Contribution to journalArticle

2009

Amphiregulin promotes the proliferation of trophoblast cells during preimplantation development of porcine embryos

Lee, J. H., Lee, E., Biswas, D., Jeung, C. S., Lee, G. S., Hyun, S. H. & Jeung, E. B., Nov 1 2009, In : Theriogenology. 72, 8, p. 1023-1031 9 p.

Research output: Contribution to journalArticle

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs

Lee, G., Papapetrou, E. P., Kim, H., Chambers, S. M., Tomishima, M. J., Fasano, C. A., Ganat, Y. M., Menon, J., Shimizu, F., Viale, A., Tabar, V., Sadelain, M. & Studer, L., Sep 17 2009, In : Nature. 461, 7262, p. 402-406 5 p.

Research output: Contribution to journalArticle

Uterine expression of epidermal growth factor family during the course of pregnancy in pigs

Kim, Y. J., Lee, G. S., Hyun, S. H., Ka, H. H., Choi, K. C., Lee, C. K. & Jeung, E. B., Oct 1 2009, In : Reproduction in Domestic Animals. 44, 5, p. 797-804 8 p.

Research output: Contribution to journalArticle

2008

Forced expression of HoxB4 enhances hematopoietic differentiation by human embryonic stem cells

Lee, G. S., Kim, B. S., Sheih, J. H. & Moore, M. A. S., Jun 30 2008, In : Molecules and cells. 25, 4, p. 487-493 7 p.

Research output: Contribution to journalArticle

High-Throughput Screening Assay for the Identification of Compounds Regulating Self-Renewal and Differentiation in Human Embryonic Stem Cells

Desbordes, S. C., Placantonakis, D. G., Ciro, A., Socci, N. D., Lee, G., Djaballah, H. & Studer, L., Jun 5 2008, In : Cell stem cell. 2, 6, p. 602-612 11 p.

Research output: Contribution to journalArticle

Osteogenic potential of embryonic stem cells in tooth sockets

Kang, H. K., Roh, S., Lee, G., Hong, S. D., Kang, H. & Min, B. M., May 1 2008, In : International journal of molecular medicine. 21, 5, p. 539-544 6 p.

Research output: Contribution to journalArticle

2007

Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells

Lee, G., Kim, H., Elkabetz, Y., Al Shamy, G., Panagiotakos, G., Barberi, T., Tabar, V. & Studer, L., Dec 1 2007, In : Nature biotechnology. 25, 12, p. 1468-1475 8 p.

Research output: Contribution to journalArticle

Isolation and initial culture of porcine inner cell masses derived from in vitro-produced blastocysts

Kim, H. S., Son, H. Y., Kim, S., Lee, G. S., Park, C. H., Kang, S. K., Lee, B. C., Hwang, W. S. & Lee, C. K., Feb 1 2007, In : Zygote. 15, 1, p. 55-63 9 p.

Research output: Contribution to journalArticle

2006

Expression of leptin ligand and receptor and effect of exogenous leptin supplement on in vitro development of porcine embryos

Kim, H. S., Lee, G. S., Kim, J. H., Kang, S. K., Lee, B. C. & Hwang, W. S., Mar 1 2006, In : Theriogenology. 65, 4, p. 831-844 14 p.

Research output: Contribution to journalArticle

2005

Characterization of pig vasa homolog gene and specific expression in germ cell lineage

Lee, G. S., Kim, H. S., Lee, S. H., Kang, M. S., Kim, D. Y., Lee, C. K., Kang, S. K., Lee, B. C. & Hwang, W. S., Nov 1 2005, In : Molecular reproduction and development. 72, 3, p. 320-328 9 p.

Research output: Contribution to journalArticle

Effect of epidermal growth factor in preimplantation development of porcine cloned embryos

Lee, G. S., Kim, H. S., Hyun, S. H., Jeon, H. Y., Nam, D. H., Jeong, Y. W., Kim, S., Kim, J. H., Kang, S. K., Lee, B. C. & Hwang, W. S., May 1 2005, In : Molecular reproduction and development. 71, 1, p. 45-51 7 p.

Research output: Contribution to journalArticle

Embryotropic effect of glycosaminoglycans and receptors in development of porcine pre-implantation embryos

Kim, H. S., Lee, G. S., Hyun, S. H., Nam, D. H., Lee, S. H., Jeong, Y. W., Kim, S., Kim, J. H., Kang, S. K., Lee, B. C. & Hwang, W. S., Mar 1 2005, In : Theriogenology. 63, 4, p. 1167-1180 14 p.

Research output: Contribution to journalArticle

Embryotropic effect of insulin-like growth factor (IGF)-I and its receptor on development of porcine preimplantation embryos produced by in vitro fertilization and somatic cell nuclear transfer

Kim, S., Lee, G. S., Lee, S. H., Soo, H., Kim, Jeong, Y. W., Kim, J. H., Kang, S. K., Lee, B. C. & Hwang, W. S., Sep 1 2005, In : Molecular reproduction and development. 72, 1, p. 88-97 10 p.

Research output: Contribution to journalArticle

Production of transgenic cloned piglets from genetically transformed fetal fibroblasts selected by green fluorescent protein

Lee, G. S., Kim, H. S., Hyun, S. H., Lee, S. H., Jeon, H. Y., Nam, D. H., Jeong, Y. W., Kim, S., Kim, J. H., Han, J. Y., Ahn, C., Kang, S. K., Lee, B. C. & Hwang, W. S., Mar 1 2005, In : Theriogenology. 63, 4, p. 973-991 19 p.

Research output: Contribution to journalArticle

The analysis of telomere length and telomerase activity in cloned pigs and cows

Jeon, H. Y., Hyun, S. H., Lee, G. S., Kim, H. S., Kim, S., Jeong, Y. W., Kang, S. K., Lee, B. C., Han, J. Y., Ahn, C. & Hwang, W. S., Jul 1 2005, In : Molecular reproduction and development. 71, 3, p. 315-320 6 p.

Research output: Contribution to journalArticle